Crystal structure of the complex of the variable domain of antibody D1.3 and turkey egg white lysozyme: A novel conformational change in antibody CDR-L3 selects for antigen

Journal of Molecular Biology

Volumn 257, Issue 5, 1996, Pages 889-894

  Braden, Bradford C ^a   Fields, Barry A ^a   Ysern, Xavier ^b   Goldbaum, Fernando A ^a,c   Dall'Acqua, William ^a   Schwarz, Frederick P ^a   Poljak, Roberto J ^a   Mariuzza, Roy A ^a  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c Instituto de Estudios de la Inmunidad Humoral   (Argentina)

Author keywords

Antibody antigen interaction; CDR conformation; Monoclonal antibody; Protein structure; X ray diffraction

Indexed keywords

ANTIGEN; GLUTAMINE; HISTIDINE; IMMUNOGLOBULIN LIGHT CHAIN; LYSOZYME; MONOCLONAL ANTIBODY; SERINE; TRYPTOPHAN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; TURKEY (BIRD);

AVES; MELEAGRIS GALLOPAVO; MURINAE;

EID: 0029870875     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0209     Document Type: Editorial

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