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Volumn 19, Issue 5-6, 1997, Pages 334-343

Evolving enzyme technology for pharmaceutical applications: Case studies

Author keywords

Biocatalysis; Biosynthesis; Carbacephem; Cephalosporin C; ECB antifungal agent; Tylosin

Indexed keywords

BETA LACTAM ANTIBIOTIC; CEPHALOSPORIN C; CEPHALOSPORIN DERIVATIVE; DEACETOXYCEPHALOSPORIN C; ECHINOCANDIN B; TYLOSIN;

EID: 0031470397     PISSN: 13675435     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jim.2900437     Document Type: Article
Times cited : (7)

References (31)
  • 1
    • 0025810296 scopus 로고
    • Deacetoxycephalosporin C hydroxylase of Streptomyces clavuligerus. Purification, characterization, bifunctionality, and evolutionary implication
    • Baker BJ, JE Dotzlaf and WK Yeh. 1991. Deacetoxycephalosporin C hydroxylase of Streptomyces clavuligerus. Purification, characterization, bifunctionality, and evolutionary implication. J Biol Chem 266: 5087-5093.
    • (1991) J Biol Chem , vol.266 , pp. 5087-5093
    • Baker, B.J.1    Dotzlaf, J.E.2    Yeh, W.K.3
  • 3
    • 0020654254 scopus 로고
    • Biosynthesis of the macrolide antibiotic tylosin: A preferred pathway from tylactone to tylosin
    • Baltz RH, ET Seno, J Stonesifer and GM Wild. 1982. Biosynthesis of the macrolide antibiotic tylosin: a preferred pathway from tylactone to tylosin. J Antibiotics 36: 131-141.
    • (1982) J Antibiotics , vol.36 , pp. 131-141
    • Baltz, R.H.1    Seno, E.T.2    Stonesifer, J.3    Wild, G.M.4
  • 4
    • 0024297217 scopus 로고
    • Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine: Macrocin O-methyltransferase from Streptomyces fradiae
    • Bauer NJ, AJ Kreuzman, JE Dotzlaf and WK Yeh. 1988. Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine: macrocin O-methyltransferase from Streptomyces fradiae. J Biol Chem 263: 15619-15625.
    • (1988) J Biol Chem , vol.263 , pp. 15619-15625
    • Bauer, N.J.1    Kreuzman, A.J.2    Dotzlaf, J.E.3    Yeh, W.K.4
  • 5
    • 0042538710 scopus 로고    scopus 로고
    • Discovery, purification, and properties of phthalyl amidase from Xanthobacter agilis
    • Briggs BS, AJ Kreuzman, C Whitesitt, WK Yeh and M Zmijewski. 1996. Discovery, purification, and properties of phthalyl amidase from Xanthobacter agilis. J Mol Catalysis 2: 53-69.
    • (1996) J Mol Catalysis , vol.2 , pp. 53-69
    • Briggs, B.S.1    Kreuzman, A.J.2    Whitesitt, C.3    Yeh, W.K.4    Zmijewski, M.5
  • 6
    • 0026710635 scopus 로고
    • Isolation of deacetoxycephalosporin C from fermentation broths of Penicillium chrysogenum transformants: Construction of a new fungal biosynthetic pathway
    • Cantwell CA, RJ Beckman, P Whiteman, SW Queener and EP Abraham. 1992. Isolation of deacetoxycephalosporin C from fermentation broths of Penicillium chrysogenum transformants: construction of a new fungal biosynthetic pathway. Proc R Soc Lond B 248: 283-289.
    • (1992) Proc R Soc Lond B , vol.248 , pp. 283-289
    • Cantwell, C.A.1    Beckman, R.J.2    Whiteman, P.3    Queener, S.W.4    Abraham, E.P.5
  • 9
    • 0023219813 scopus 로고
    • Copurification and characterization of deacetoxycephalosporin C synthetase/hydroxylase from Cephalosporium acremonium
    • Dotzlaf JE and WK Yeh. 1987. Copurification and characterization of deacetoxycephalosporin C synthetase/hydroxylase from Cephalosporium acremonium. J Bacteriol 169: 1611-1618.
    • (1987) J Bacteriol , vol.169 , pp. 1611-1618
    • Dotzlaf, J.E.1    Yeh, W.K.2
  • 10
    • 0024380165 scopus 로고
    • Purification and properties of deacetoxycephalosporin C synthase from recombinant Escherichia coli and its comparison with the native enzyme from Streptomyces clavuligerus
    • Dotzlaf JE and WK Yeh. 1989. Purification and properties of deacetoxycephalosporin C synthase from recombinant Escherichia coli and its comparison with the native enzyme from Streptomyces clavuligerus. J Biol Chem 264: 10219-10227.
    • (1989) J Biol Chem , vol.264 , pp. 10219-10227
    • Dotzlaf, J.E.1    Yeh, W.K.2
  • 12
    • 0027312713 scopus 로고
    • Purification and properties of NADPH-dependent tylosin reductase from Streptomyces fradiae
    • Huang SL, TC Hassell and WK Yeh. 1993. Purification and properties of NADPH-dependent tylosin reductase from Streptomyces fradiae. J Biol Chem 268: 18987-18993.
    • (1993) J Biol Chem , vol.268 , pp. 18987-18993
    • Huang, S.L.1    Hassell, T.C.2    Yeh, W.K.3
  • 13
    • 0022019449 scopus 로고
    • Deacetoxycephalosporin C synthetase and deacetoxycephalosporin C hydroxylase are two separate enzymes in Streptomyces clavuligerus
    • Jensen SE, DWS Westlake and S Wolfe. 1985. Deacetoxycephalosporin C synthetase and deacetoxycephalosporin C hydroxylase are two separate enzymes in Streptomyces clavuligerus. J Antibiot Tokyo 38: 263-265.
    • (1985) J Antibiot Tokyo , vol.38 , pp. 263-265
    • Jensen, S.E.1    Westlake, D.W.S.2    Wolfe, S.3
  • 14
    • 0025956841 scopus 로고
    • Cloning and sequencing of the β-lactam hydroxylase gene (cefF) from Streptomyces clavuligerus: Gene duplication may have led to separate hydroxylase and expandase activities in Actinomyces
    • Kovacevic S and JR Miller. 1991. Cloning and sequencing of the β-lactam hydroxylase gene (cefF) from Streptomyces clavuligerus: gene duplication may have led to separate hydroxylase and expandase activities in Actinomyces. J Bacteriol 173: 398-400.
    • (1991) J Bacteriol , vol.173 , pp. 398-400
    • Kovacevic, S.1    Miller, J.R.2
  • 15
    • 0024535307 scopus 로고
    • Cloning, characterization, and expression in Escherichia coli of Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase
    • Kovacevic S, BJ Weigel, MB Tobin, TD Ingolia and JR Miller. 1989. Cloning, characterization, and expression in Escherichia coli of Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase. J Bacteriol 171: 754-760.
    • (1989) J Bacteriol , vol.171 , pp. 754-760
    • Kovacevic, S.1    Weigel, B.J.2    Tobin, M.B.3    Ingolia, T.D.4    Miller, J.R.5
  • 16
    • 0023768504 scopus 로고
    • Two distinctive O-methyltransferases catalyzing penultimate and terminal reactions of macrolide antibiotic (tylosin) biosynthesis: Substrate specificity, enzyme inhibition and kinetic mechanism
    • Kreuzman AJ, JR Turner and WK Yeh. 1988. Two distinctive O-methyltransferases catalyzing penultimate and terminal reactions of macrolide antibiotic (tylosin) biosynthesis: substrate specificity, enzyme inhibition and kinetic mechanism. J Biol Chem 263: 15626-15633.
    • (1988) J Biol Chem , vol.263 , pp. 15626-15633
    • Kreuzman, A.J.1    Turner, J.R.2    Yeh, W.K.3
  • 17
    • 26844472963 scopus 로고
    • Purification and properties of cell-associated echinocandin B deacylase from Actinoplanes utahensis
    • Chicago, IL
    • Kreuzman AJ and WK Yeh. 1990. Purification and properties of cell-associated echinocandin B deacylase from Actinoplanes utahensis. In: Abstracts of The ASM Conference on Biotechnology, p 10, Chicago, IL.
    • (1990) Abstracts of the ASM Conference on Biotechnology , pp. 10
    • Kreuzman, A.J.1    Yeh, W.K.2
  • 18
    • 0031468279 scopus 로고    scopus 로고
    • Enzymatic synthesis of diastereospecific carbacephem intermediates using serine hydroxymethyltransferase
    • Kreuzman AJ, JM Zock, JT Vicenzi, JE Dotzlaf, SW Queener and WK Yeh. 1997. Enzymatic synthesis of diastereospecific carbacephem intermediates using serine hydroxymethyltransferase. J Ind Microbiol 19: 369-377.
    • (1997) J Ind Microbiol , vol.19 , pp. 369-377
    • Kreuzman, A.J.1    Zock, J.M.2    Vicenzi, J.T.3    Dotzlaf, J.E.4    Queener, S.W.5    Yeh, W.K.6
  • 19
    • 0029670577 scopus 로고    scopus 로고
    • Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents
    • Moore J and FH Arnold. 1996. Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents. Nat Biotech 14: 458-467.
    • (1996) Nat Biotech , vol.14 , pp. 458-467
    • Moore, J.1    Arnold, F.H.2
  • 22
    • 0020320421 scopus 로고
    • S-Adenosyl-L-methionine: Macrocin O-methyltransferase activities in a series of Streptomyces fradiae mutants that produce different levels of macrolide antibiotic tylosin
    • Seno ET and RH Baltz. 1982. S-Adenosyl-L-methionine: macrocin O-methyltransferase activities in a series of Streptomyces fradiae mutants that produce different levels of macrolide antibiotic tylosin. Antimicrob Agents Chemother 21: 756-763.
    • (1982) Antimicrob Agents Chemother , vol.21 , pp. 756-763
    • Seno, E.T.1    Baltz, R.H.2
  • 24
    • 0018790274 scopus 로고
    • Toluene dioxygenase: Purification of iron-surfur protein by affinity chromatography
    • Subramaman V, TN Liu, WK Yeh and DT Gibson. 1979. Toluene dioxygenase: purification of iron-surfur protein by affinity chromatography. Biochem Biophys Res Commun 91: 1131-1139.
    • (1979) Biochem Biophys Res Commun , vol.91 , pp. 1131-1139
    • Subramaman, V.1    Liu, T.N.2    Yeh, W.K.3    Gibson, D.T.4
  • 25
    • 0019429534 scopus 로고
    • Purification and properties of NADH-ferredoxinTOL reductase: A component of toluene dioxygenase from Pseudomonas putida
    • Subramanian V, TN Liu, WK Yeh, M Narro and DT Gibson. 1981. Purification and properties of NADH-ferredoxinTOL reductase: a component of toluene dioxygenase from Pseudomonas putida. J Biol Chem 256: 2723-2730.
    • (1981) J Biol Chem , vol.256 , pp. 2723-2730
    • Subramanian, V.1    Liu, T.N.2    Yeh, W.K.3    Narro, M.4    Gibson, D.T.5
  • 26
    • 0021895134 scopus 로고
    • Purification and properties of ferredoxinTOL: A component of toluene dioxygenase from Pseudomonas putida F1
    • Subramanian V, TN Liu, WK Yeh, CM Serdar, LP Wacket and DT Gibson. 1985. Purification and properties of ferredoxinTOL: a component of toluene dioxygenase from Pseudomonas putida F1. J Biol Chem 260: 2355-2363.
    • (1985) J Biol Chem , vol.260 , pp. 2355-2363
    • Subramanian, V.1    Liu, T.N.2    Yeh, W.K.3    Serdar, C.M.4    Wacket, L.P.5    Gibson, D.T.6
  • 27
    • 0024358924 scopus 로고
    • Purification and properties of isopenicillin N epimerase from Streptomyces clavuligerus
    • Usui S and CA Yu. 1989. Purification and properties of isopenicillin N epimerase from Streptomyces clavuligerus. Biochim Biophys Acta 999: 78-85.
    • (1989) Biochim Biophys Acta , vol.999 , pp. 78-85
    • Usui, S.1    Yu, C.A.2
  • 28
    • 0019120488 scopus 로고
    • Evolutionary divergence of coselected β-ketoadipate enol-lactone hydrolases in Acinetobacter calcoaceticus
    • Yeh WK, P Flether and LN Ornston. 1980. Evolutionary divergence of coselected β-ketoadipate enol-lactone hydrolases in Acinetobacter calcoaceticus. J Biol Chem 255: 6342-6346.
    • (1980) J Biol Chem , vol.255 , pp. 6342-6346
    • Yeh, W.K.1    Flether, P.2    Ornston, L.N.3
  • 29
    • 0027082943 scopus 로고
    • Enzymes for epimenzation of isopenicillin N, ring expansion of penicillin N, and 3′-hydroxylation of deacetoxycephalosporin C: Function, evolution, refolding and enzyme engineering
    • Yeh WK, SK Ghag and SW Queener. 1992. Enzymes for epimenzation of isopenicillin N, ring expansion of penicillin N, and 3′-hydroxylation of deacetoxycephalosporin C: function, evolution, refolding and enzyme engineering. Ann NY Acad Sci 672: 396-408.
    • (1992) Ann NY Acad Sci , vol.672 , pp. 396-408
    • Yeh, W.K.1    Ghag, S.K.2    Queener, S.W.3
  • 31
    • 0025612892 scopus 로고
    • Potential industrial use of cephalosporin biosynthetic enzymes and genes
    • Yeh WK and SW Queener. 1990. Potential industrial use of cephalosporin biosynthetic enzymes and genes. Ann NY Acad Sci 613: 128-141.
    • (1990) Ann NY Acad Sci , vol.613 , pp. 128-141
    • Yeh, W.K.1    Queener, S.W.2


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