Enzymatic synthesis of diastereospecific carbacephem intermediates using serine hydroxymethyltransferase

Journal of Industrial Microbiology and Biotechnology

Volumn 19, Issue 5-6, 1997, Pages 369-377

  Kreuzman, A J ^a   Zock, J M ^a   Dotzlaf, J E ^a   Vicenzi, J T ^a   Queener, S W ^a   Yeh, W K ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Carbacephem; Chemo enzymatic synthesis; Diastereospecificity; PLP; Serine hydroxymethyltransferase

Indexed keywords

CARBACEPHEM DERIVATIVE; GLYCINE HYDROXYMETHYLTRANSFERASE;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; ENZYME SPECIFICITY; ESCHERICHIA COLI; NONHUMAN; PARTIAL DRUG SYNTHESIS; PROTEIN EXPRESSION; RABBIT; REACTION ANALYSIS; STEREOSPECIFICITY;

ANIMALS; CEPHALOSPORINS; GLYCINE HYDROXYMETHYLTRANSFERASE; KINETICS; RABBITS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 0031468279     PISSN: 13675435     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jim.2900395     Document Type: Article

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