Food carotenoids and cancer prevention: An overview of current research

Trends in Food Science and Technology

Volumn 8, Issue 12, 1997, Pages 406-413

  Astorg, Pierre ^a  

^a CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; EPIDEMIOLOGY; FOOD PRODUCTS; FRUITS; RESEARCH; VITAMINS;

BETA CAROTENE; CANCER PREVENTION; FOOD CAROTENOIDS; VITAMIN A;

NUTRITION;

EID: 0031463843     PISSN: 09242244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-2244(97)01092-3     Document Type: Review

References (65)

1. Straub, O. (1987) Key to Carotenoids (2nd edn), pp. 1-296, Birkhäuser Verlag, Basel, Switzerland
2. Armstrong, G.A. and Hearst, J.E. (1996) 'Genetics and Molecular Biology of Carotenoid Biosynthesis' in FASEB J. 10, 228-237
3. Demmig-Adams, B., Gilmore, A.M. and Adams, W.W., III (1996) 'In Vivo Functions of Carotenoids in Higher Plants' in FASEB J. 10, 403-412
4. Britton, G. (1995) 'Structure and Properties of Carotenoids in Relation to Function' in FASEB J. 9, 1551-1558
5. Palozza, P. and Krinsky, N.I. (1992) 'Antioxidant Effects of Carotenoids In Vivo and In Vitro: An Overview' in Methods Enzymol. 213, 403-420
6. Rice-Evans, C., Sampson, J., Bramley, P. and Holloway, D. (1997) 'Commentary: Why Do We Expect Carotenoids to be Antioxidants In Vivo?' in Free Radic. Res. 26, 381-398
7. Mordi, R.C. et al. (1993) 'Oxidative Degradation of β-Carotene and β-Apo-8′-carotenal' in Tetrahedron 49, 911-928
8. Mangels, A.R., Holden, J.M., Beecher, G.R., Forman, M.R. and Lanza, E. (1993) 'Carotenoids in Fruits and Vegetables: An Evaluation of Analytic Data' in J. Am. Diet. Assoc. 93, 284-296
9. Khachik, F. et al. (1997) 'Identification, Quantification, and Relative Concentrations of Carotenoids and Their Metabolites in Human Milk and Serum' in Anal. Chem. 64, 2111-2122
10. Parker, R.S. (1996) 'Absorption, Metabolism and Transport of Carotenoids' in FASEB J. 10, 542-551
11. Devery, J. and Milborrow, B.V. (1994) 'β-Carotene-15,15′-Dioxygenase (EC 1.13.11.21) Isolation Reaction Mechanism and an Improved Assay Procedure' in Br. J. Nutr. 72, 397-414
12. Duszka, C. et al. (1996) 'Rat Intestinal β-Carotene Dioxygenase Activity is Located Primarily in the Cytosol of Mature Jejunal Enterocytes' in J. Nutr. 126, 2550-2556
13. Moon, R.C., Mehta, R.G. and Rao, K.V.N. (1994) 'Retinoids and Cancer in Experimental Animals' in The Retinoids (2nd edn) (Sporn, M., Roberts, A. and Goodman, D., eds), pp. 327-371, Academic Press
14. Mayne, S.T., Graham, S. and Zheng, T. (1991) 'Dietary Retinol: Prevention or Promotion of Carcinogenesis in Humans?' in Cancer Causes Control 2, 443-450
15. Campbell, D.R. et al. (1994) 'Plasma Carotenoids as Biomarkers of Vegetable and Fruit Intake' in Cancer Epidemiol. Biomarkers Prev. 3, 493-500
16. Peto, R., Doll, R., Buckley, J.D. and Sporn, M.B. (1981) 'Can β-Carotene Materially Reduce Lung Cancer Rates?' in Nature 290, 201-209
17. Sun, Y. (1990) 'Free Radicals, Antioxidant Enzymes, and Carcinogenesis' in Free Radic. Biol. Med. 8, 583-599
18. Ziegler, R.G. (1991) 'Vegetables, Fruits, and Carotenoids and the Risk of Cancer' in Am. J. Clin. Nutr. 53(Suppl.), 251S-259S
19. Ziegler, R.G., Mayne, S.T. and Swanson, C.A. (1996) 'Nutrition and Lung Cancer' in Cancer Causes Control 7, 157-177
20. Ziegler, R.G. et al. (1992) 'Does β-Carotene Explain Why Reduced Cancer Risk is Associated with Vegetable and Fruit Intake?' in Cancer Res. 52(Suppl.), 2060S-2066S
21. Van Poppel, G. and Goldbohm, A. (1995) 'Epidemiologic Evidence for β-Carotene and Cancer Prevention' in Am. J. Clin. Nutr. 62(Suppl.), 1393S-1402S
22. Block, G., Patterson, B. and Subar, A. (1992) 'Fruit, Vegetables, and Cancer Prevention: A Review of the Epidemiologic Evidence' in Nutr. Cancer 18, 1-29
23. Le Marchand, L. et al. (1993) 'Intake of Specific Carotenoids and Lung Cancer Risk' in Cancer Epidemiol. Biomarkers Prev. 2, 183-187
24. Ziegler, R.G. et al. (1996) 'The Importance of α-Carotene, β-Carotene, and Other Phytochemicals in the Etiology of Lung Cancer' in J. Natl. Cancer Inst. 88, 612-615
25. Giovanucci, E. et al. (1995) 'Increase of Carotenoids and Retinol in Relation to Risk of Prostate Cancer' in J. Natl. Cancer Inst. 87, 1767-1776
26. Gerster, H. (1997) 'The Potential Role of Lycopene for Human Health' in J. Am. Coll. Nutr. 16, 109-126
27. Steinmetz, K.A., Potter, J.D. and Folsom, A.R. (1993) 'Vegetables, Fruits, and Lung Cancer in the Iowa Women's Health Study' in Cancer Res. 53, 536-543
28. Mayne, S.T. (1997) 'Antioxidant Nutrients and Cancer Incidence and Mortality: An Epidemiologic Perspective' in Adv. Pharmacol. 38, 657-675
29. Krinsky, N.I. (1991) 'Effects of Carotenoids in Cellular and Animal Systems' in Am. J. Clin. Nutr. 53(Suppl.), 238S-246S
30. Gerster, H. (1993) 'Anticarcinogenic Effects of Common Carotenoids' in Int. J. Vitam. Nutr. Res. 63, 93-121
31. Alabaster, O., Tang, Z.C., Frost, A. and Shivapurkar, N. (1995) 'Effect of β-Carotene and Wheat Bran Fiber on Colonic Aberrant Crypt and Tumor Formation in Rats Exposed to Azoxymethane and High Dietary Fat' in Carcinogenesis 16, 127-132
32. Nagasawa, H., Mitamura, T., Sakamoto, S. and Yamamoto, K. (1995) 'Effect of Lycopene on Spontaneous Mammary Tumor Development in SHN Virgin Mice' in Anticancer Res. 15, 1173-1178
33. Tanaka, T. et al. (1995) 'Chemoprevention of Rat Oral Carcinogenesis by Naturally Occuring Xanthophylls Astaxanthin and Canthaxanthin' in Cancer Res. 55, 4059-4064
34. Astorg, P., Gradelet, S., Bergès, R. and Suschetet, M. (1997) 'Dietary Lycopene Decreases the Initiation of Liver Preneoplastic Foci by Diethylnitrosamine in the Rat' in Nutr. Cancer 29, 60-68
35. Gerster, H. (1995) 'β-Carotene, Vitamin E and Vitamin C in Different Stages of Experimental Carcinogenesis' in Eur. J. Clin. Nutr. 49, 155-168
36. Murakoshi, M. et al. (1992) 'Potent Preventive Action of α-Carotene Against Carcinogenesis: Spontaneous Liver Carcinogenesis and Promoting Stage of Lung and Skin Carcinogenesis in Mice are Suppressed More Effectively by α-Carotene Than by β-Carotene' in Cancer Res. 52, 6583-6587
37. Krinsky, N.I. (1993) 'Micronutrients and Their Influence on Mutagenicity and Malignant Transformation' in Ann. New York Acad. Sci. 686, 229-242
38. Krinsky, N.I. (1994) 'Carotenoids and Cancer: Basic Research Studies' in Natural Antioxidants in Human Health and Disease (Frei, B., ed.), pp. 239-261, Academic Press
39. Gradelet, S. et al. (1996) 'Effects of Canthaxanthin, Astaxanthin, Lycopene and Lutein on Liver Xenobiotic-metabolizing Enzymes in the Rat' in Xenobiotica 26, 49-63
40. Gradelet, S., Leclerc, J., Siess, M-H. and Astorg, P. (1996) 'β-Apo-8′-Carotenal, But Not β-Carotene, is a Strong Inducer of Liver Cytochromes P450 1A1 and 1A2 in Rat' in Xenobiotica 26, 909-919
41. Gradelet, S. et al. (1997) 'Ah Receptor-dependent CYP1A Induction by two Carotenoids, Canthaxanthin and β-Apo-8′-Carotenal, with no Affinity for the TCDD Binding Site' in Biochem. Pharmacol. 54, 307-315
42. Levy, J. et al. (1995) 'Lycopene is a More Potent Inhibitor of Human Cancer Cell Proliferation Than Either β-Carotene or α-Carotene' in Nutr. Cancer 24, 257-266
43. Bertram, J.S. (1993) 'Cancer Prevention by Carotenoids: Mechanistic Studies in Cultured Cells' in Carotenoids in Human Health (Canfield, L.M., Krinsky, N.I. and Olson, J.A., eds), pp. 177-191, New York Academy of Sciences, New York, NY, USA
44. Nikawa, T. et al. (1995) 'Efficacy of All-trans-β-Carotene, Canthaxanthin, and All-trans-, 9-cis-, and 4-Oxoretinoic Acids in Inducing Differentiation of an F9 Embryonal Carcinoma RARβ-lacZ Reporter Cell Line' in Arch. Biochem. Biophys. 316, 665-672
45. Acevedo, P. and Bertram, J. (1995) 'Liarozole Potentiates the Chemopreventive Activity of and the Up-regulation of Gap Junctional Communication and Connexin 43 Expression by Retinoic Acid and β-Carotene in 10T1/2 Cells' in Carcinogenesis 16, 2215-2222
46. Hanusch, M., Stahl, W., Schulz, W. and Sies, H. (1995) 'Induction of Gap-junctional Communication by 4-Oxoretinoic Acid Generated From Its Precursor Canthaxanthin' in Arch. Biochem. Biophys. 317, 423-428
47. Schwartz, J.L., Flynn, E. and Shklar, G. (1990) 'The Effects of Carotenoids on the Antitumor Immune Response In Vivo and In Vitro with Hamster and Mouse Immune Effectors' in Micronutrients and Immune Functions (Bendich, A. and Chandra, R.K., eds), pp. 92-109, New York Academy of Sciences, New York, NY, USA
48. Bendich, A. (1996) 'Antioxidant Vitamins and Human Immune Response' in Vitam. Horm. 52, 35-62
49. Meyers, D.G. (1996) 'The Safety of Antioxidant Vitamins' in Arch. Intern. Med. 156, 925-935
50. Mayne, S.T. (1996) 'β-Carotene, Carotenoids, and Disease Prevention in Humans' in FASEB J. 10, 690-701
51. Mayne, S.T., Handelman, G.J. and Beecher, G. (1996) 'β-Carotene and Lung Cancer Promotion in Heavy Smokers - A Plausible Relationship?' in J. Natl. Cancer Inst. 88, 1513-1515
52. Blot, W.J. et al. (1993) 'Nutrition Intervention Trials in Linxian, China: Supplementation with Specific Vitamin/Mineral Combinations, Cancer Incidence, and Disease-specific Mortality in the General Population' in J. Natl. Cancer Inst. 85, 1483-1491
53. The Alpha Tocopherol, Beta Carotene Cancer Prevention Study Group (1994) 'The Effect of Vitamin E and Beta Carotene on the Incidence of Lung Cancer and Other Cancers in Male Smokers' in New Engl. J. Med. 330, 1029-1035
54. Albanes, D. et al. (1996) 'α-Tocopherol and β-Carotene Supplements and Lung Cancer Incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: Effects of Base-line Characteristics and Study Compliance' in J. Natl. Cancer Inst. 88, 1560-1570
55. Omenn, G.S. et al. (1996) 'Effects of a Combination of Beta Carotene and Vitamin A on Lung Cancer and Cardiovascular Disease' in New Engl. J. Med. 334, 1150-1155
56. Omenn, G.S. et al. (1996) 'Risk Factors for Lung Cancer and for Intervention Effects in CARET, the Beta-carotene and Retinol Efficacy Trial' in J. Natl. Cancer Inst. 88, 1550-1559
57. Hennekens, C.H. et al. (1996) 'Lack of Effect of Long-term Supplementation with Beta Carotene on the Incidence of Malignant Neoplasms and Cardiovascular Disease' in New Engl. J. Med. 334, 1146-1149
58. Olson, J.A. (1996) 'Benefits and Liabilities of Vitamin A and Carotenoids' in J. Nutr. 126(Suppl.), 1208S-1212S
59. Kostic, D., White, W.S. and Olson, J.A. (1995) 'Intestinal Absorption, Serum Clearance, and Interactions Between Lutein and β-Carotene When Administered to Human Adults in Separate or Combined Oral Doses' in Am. J. Clin. Nutr. 62, 604-610
60. Gerster, H. (1995) 'Intermediate Cancer Biomarkers and Their Use in β-Carotene Studies in Humans' in Int. J. Vitam. Nutr. Res. 66, 3-18
61. Nishino, H. (1995) 'Cancer Chemoprevention by Natural Carotenoids and Their Related Compounds' in J. Cell. Biochem. 22, 231-235
62. Stahl, W. and Sies, H. (1996) 'Lycopene: A Biologically Important Carotenoid for Humans?' in Arch. Biochem. Biophys. 336, 1-9
63. Khachik, F., Beecher, G.R. and Smith, J.C., Jr (1995) 'Lutein, Lycopene, and Their Oxidative Metabolites in Chemoprevention of Cancer' in J. Cell. Biochem. 22(Suppl.), 236-246
64. Loft, S. and Poulsen, H.E. (1996) 'Cancer Risk and Oxidative DNA Damage in Man' in J. Mol. Med. 74, 297-312
65. Kelloff, G.J. et al. (1997) 'New Agents for Cancer Chemoprevention' in J. Cell. Biochem. 265, 1-28