Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches

Seminars in Immunology

Volumn 8, Issue 3, 1996, Pages 141-150

  Tumas Brundage, Kathleen ^a   Vora, Kalpit A ^a   Giusti, Angela M ^a,b   Manser, Tim ^a  

^a THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

^b R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

3' IgH enhancer; Homologous recombination; Hypermutation; V(H) promoter

Indexed keywords

CIS ACTING ELEMENT;

ANTIBODY STRUCTURE; ARTICLE; CHIMERA; GENETIC RECOMBINATION; IMMUNOGENETICS; IMMUNOGLOBULIN VARIABLE REGION; MOUSE; NONHUMAN; PROMOTER REGION; SOMATIC MUTATION; TRANSGENE;

EID: 0029996999     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.1996.0018     Document Type: Article

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