Angiogenesis by fibroblast growth factor 4 is mediated through an autocrine up-regulation of vascular endothelial growth factor expression

Cancer Research

Volumn 57, Issue 24, 1997, Pages 5590-5597

  Deroanne, Christophe F ^a   Hajitou, Amin ^a   Calberg Bacq, Claire M ^a   Nusgens, Betty V ^a   Lapière, Charles M ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; MATRIX METALLOPROTEINASE; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; DOSE RESPONSE; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; TUMOR VASCULARIZATION;

ANIMALS; CELLS, CULTURED; COLLAGEN; CULTURE MEDIA; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 3; FIBROBLAST GROWTH FACTORS; HUMANS; LYMPHOKINES; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; PHENOTYPE; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0031457364     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Yamasaki, M., Miyake, A., Tagashari, S., and Itoh, N. Structure and expression of the rat mRNA encoding a novel member of the fibroblast growth factor family. J. Biol. Chem., 271: 15918-15921, 1996
2. Smallwood, P. M., Munoz-Sanjuan, I., Tong, P., Macke, J. P., Hendry, S. H., Gilbert, D. J., Copeland, N. G., Jenkins, N. A., and Nathans, J. Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc. Natl. Acad. Sci. USA, 93: 9850-9857, 1996.
3. Coulier, F., Pontarotti, P., Roubin, R., Hartung, H., Goldfarb, M., and Birnbaum, D. Of worms and men: an evolutionary perspective on the fibroblast growth factor (FGF) and FGF receptor families. J. Mol. Evol., 44: 43-56, 1997.
4. Mason, I. J. The ins and outs of fibroblast growth factors. Cell, 78: 547-552, 1994.
5. Friesel, R. E., and Maciag, T. Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction. FASEB J., 9: 919-925, 1995.
6. Goldfarb, M. Functions of fibroblast growth factors in vertebrate development. Cytokine Growth Factor Rev., 7: 311-325, 1996.
7. Basilico, C., and Moscatelli, D. The FGF family of growth factors and oncogenes. Adv. Cancer Res., 59: 115-165, 1992.
8. Dickson, C., Smith, R., Brookes, S., and Peters, G. Tumorigenesis by mouse mammary tumor virus: proviral activation of a cellular gene in the common integration region int-2. Cell, 37: 529-536, 1984.
9. Peters, G., Brookes, S., Smith, R., Placzeck, M.. and Dickson, C. The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors. Proc. Natl. Acad. Sci. USA, 86: 5678-5682, 1989.
10. Clausse, N., Smith, R., Calberg-Bacq, C. M., Peters, G., and Dickson, C. Mouse mammary tumor virus activates Fgf-3/int-2 less frequently in tumors from virgin than from parous mice. Int. J. Cancer, 55: 157-163, 1993.
11. Murakami, A., Tanaka, H., and Matsuzama, A. Association of hst gene expression with metastatic phenotype in mouse mammary tumors. Cell Growth Differ., 1: 225-231, 1990.
12. Shackleford, G., Macarthur, C., Kwan, H., and Varmus, H. Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-I transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4. Proc. Natl. Acad. Sci. USA, 90: 740-744, 1993.
13. Günzburg, W. H., Salmons, B., Schalaeffli, A., Moritz-Legrand, S., Jones, W., Sarkar, N. H., and Ullrich, R. Expression of the oncogenes mil and ras abolishes the in vivo differentiation of the mammary epithelial cells. Carcinogenesis (Lond.), 9: 1849-1856, 1988.
14. Hajitou, A., and Calberg-Bacq, C-M. Fibroblast growth factor 3 is tumorigenic for mouse mammary cells orthotopically implanted in nude mice. Int. J. Cancer, 63: 702-709, 1995.
15. Hanahan, D., and Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86: 353-364, 1996.
16. D'Amore, P. A., and Shima, D. T. Tumor angiogenesis: a physiological process or genetically determined? Cancer Metastasis Rev., 15: 205-212, 1996.
17. Montesano, R., and Orci, L. Tumor-promoting phorbol esters induce angiogenesis in vitro, Cell, 42: 469-477, 1985.
18. 1 phase of the cell cycle. Cancer Res., 54: 2073-2076, 1994.
19. Jaffe, E. A., Nachman, R. L., Becker, C. G., and Minick, C. R. Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J. Clin. Invest., 52: 2745-2756, 1973.
20. Deroanne, C. F., Colige, A. C., Nusgens, B. V., and Lapière, C. M. Modulation of expression and assembly of vinculin during in vitro fibrillar collagen-induced angiogenesis and its reversal, Exp. Cell Res., 224: 215-223, 1996.
21. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
22. Towbin, H., Staehelin, T., and Gordon, J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA, 76: 4350-4354, 1979.
23. Souttou, B., Gamby, C., Crepin, M., and Hamelin, R. Tumoral progression of human breast epithelial cells secreting FGF2 and FGF4. Int. J. Cancer, 68: 675-681, 1996.
24. Chirgwin, J. M., Przybyla, A. E., Mac Donald, R. J., and Rutter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18: 5294-5299, 1979.
25. Lambert, C. A., Soudant, P. E., Nusgens, B. V., and Lapière, C. M. Pretranslational regulation of extracellular matrix macromolecules and collagenase expression in fibroblasts by mechanical forces. Lab. Invest., 66: 444-451, 1992.
26. Angel, P., Poting, A., Mallik, U., Rahmsdorf, H. J., Schorpp, M., and Herrlich, P. Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts. Mol. Cell. Biol., 6: 1760-1767, 1986.
27. Docherty, A. J. P., Lyons, L., Smith, B. J., Wright, E. M., Stephens, P. E., and Harris, T. J. R. Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature (Lond.), 318: 66-69, 1985.
28. r 72,000 type IV collagenase in human colonic adenocarcinoma. Cancer Res., 51: 439-444, 1991.
29. Stetler-Stevenson, W. G., Krutsch, H. C., and Liotta, L. Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family. J. Biol. Chem., 264: 17374-17378, 1989.
30. Wernert, N., Raes, M. B., Lassalle, P., Dehouck, M-P., Gosselin, B., and Stehelin, D. C-ets1 proto-oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in humans. Am. J. Pathol., 140: 119-127, 1992.
31. Vandenbunder, B., Pardanaud, L., Jaffredo, T., Mirabel, M. A., and Stehelin, D. Complementary patterns of expression of c-ets1, c-myb, and c-myc in the blood forming system of the chick embryo. Development (Camb.), 107: 265-274, 1989.
32. Iwasaka, C., Tanaka, K., Abe, M., and Sato, Y. Ets-1 regulates angiogenesis by inducing the expression of urokinase-type plasminogen activator and matrix metalloproteinase-1 and the migration of vascular endothelial cells. J. Cell. Physiol., 169: 522-531, 1996.
33. Jouanneau, J., Moens, G., Montesano, R., and Thiery J-P. Fgf-1 but not Fgf-4 secreted by carcinoma cells promotes in vitro and in vivo angiogenesis and rapid tumor proliferation. Growth Factors, 12: 37-47, 1995.
34. Adams, L. M., Ethier, S. P., and Ullrich, R. L. Enhanced in vitro proliferation and in vivo tumorigenic potential of mammary epithelium from BALB/c mice exposed in vivo to γ-radiation and/or 7,12-dimethylbenz(a)anthracene. Cancer Res., 47: 4425-4431, 1987.
35. Mc Leskey, S. W., Kurebayashi, J., Honig, S. F., Zwiebel, J., Lippman, M. E., Dickson, R. B., and Kern, F. G. Fibroblast growth factor 4 transfection of MCF-7 cells produces cell lines that are tumorigenic and metastatic in ovariectomized or tamoxifen-treated athymic nude mice. Cancer Res., 53: 2168-2177, 1993.
36. Rak, J., Filmus, J., Finkenzeller, G., Grugel, S., Marmé, D., and Kerbel, R. S. Oncogenes as inducers of tumor angiogenesis. Cancer Metastasis Rev., 14: 263-277, 1995.
37. Delli Bovi, P., and Basilico, C. Isolation of a rearranged human transforming gene following transfection of Kaposi sarcoma DNA. Proc. Natl. Acad. Sci. USA, 84: 5660-5664, 1987.
38. Talarico, D., and Basilico, C. The kFGF/hst oncogene induces transformation through an autocrine mechanism that requires extracellular stimulation of the mitogenic pathway. Mol. Cell. Biol., 11: 1138-1145, 1991.
39. Yoshida, T., Ishimura, K., Sakamoto, H., Yokota, J., Hirohashi, S., Igarashi, K., Sudo, K., and Terada, M. Angiogenic activity of the recombinant hst-1 protein. Cancer Lett., 83: 261-268, 1994.
40. Kurebayashi, J., McLeskey, S. W., Johnson, D. J., Lippman, M. E., Dickson, R. B., and Kern, F. G. Quantitative demonstration of spontaneous metastasis by MCF-7 human breast cancer cells cotransfected with fibroblast growth factor 4 and LacZ. Cancer Res., 53: 2178-2187, 1993.
41. Miyagawa, K., Sakamoto, H., Yoshida, T., Yamashita, Y., Mitsui, Y., Furusawa, M., Maeda, S., Takaku, F., Sugimura, T., and Terada, M. hst-1 transforming protein: expression in silkworm cells and characterization as a novel heparin-binding growth factor. Oncogene, 3: 383-389, 1988.
42. Delli Bovi, P., Curatola, A. M., Newman, K. N., Sato, Y., Moscatelli, D., Hewick, R. M., Rifkin, D., and Basilico, C. Processing, secretion and biological properties of a novel growth factor of the fibroblast growth factor family with oncogenic potentialities. Mol. Cell. Biol., 8: 2933-2941, 1988.
43. Thomas, K. A. Vascular endothelial growth factor, a potent and selective angiogenic agent. J. Biol. Chem., 271: 603-606, 1996.
44. Arbiser, J. L., Moses, M. A., Fernandez, C. A., Ghiso, N., Cao, Y., Klauber, N., Frank, D., Brownlee, M., Flynn, E., Parangi, S., Byers, H. R., and Folkman, J. Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways. Proc. Natl. Acad. Sci. USA, 94: 861-866, 1997.
45. Larcher, F., Robles, A. I., Duran, H., Murillas, R., Quintanilla, M., Cano, A., Conti, C. J., and Jorcano, J. L. Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels. Cancer Res., 56: 5391-5396, 1996.
46. Kolch, W., Martiny-Baron, G., Kieser, A., and Marme, D. Regulation of the expression of the VEGF/VPF and its receptors: role in tumor angiogenesis. Breast. Cancer Res. Treat., 36: 139-155, 1995.
47. Goto, F., Goto, K., Weindel, K., and Folkman, J. Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gel. Lab. Invest., 69: 491-493, 1993.
48. Unemori, E. N., Ferrara, N., Bauer, E. A., and Amento, E. P. Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J. Cell. Physiol., 153: 557-562, 1992.
49. Fisher, C., Gilbertson-Beadling, S., Powers, E. A., Petzold, G., Poorman, R., and Mitchell M. A. Interstitial collagenase is required for angiogenesis in vitro. Dev. Biol., 162: 499-510, 1994.
50. Wernert, N., Gilles, F., Fafeur, V., Bouali, F., Raes, M. B., Pyke, C., Dupressoir, T., Seitz, G., Vandenbunder, B., and Stehelin, D. Stromal expression of c-Etsl transcription factor correlates with tumor invasion. Cancer Res., 54: 5683-5688, 1994.
51. Seymour, L. W., Shoaibi, M. A., Martin, A., Ahmed, A., Elvin, P., Kerr. D. J., and Wakelam, M. J. Vascular endothelial growth factor stimulates protein kinase C-dependent phospholipase D activity in endothelial cells. Lab. Invest., 75: 427-437, 1996.
52. Guthridge, M. A., Seldin, M., and Basilico, C. Induction of expression of growth-related genes by FGF-4 in mouse fibroblasts. Oncogene, 12: 1267-1278, 1996.
53. Omitz, D. M., Xu. J.. Colvin, J. S., McEwen, D. G., Mac-Arthur, C. A., Coulier, F., Gao, G., and Goldfarb, M. Receptor specificity of the fibroblast growth factor family. J. Biol. Chem., 271: 15292-15297, 1996.