Convenient, nonradioactive, heteroduplex-based methods for identifying recurrent mutations in the BRCA1 and BRCA2 genes

Diagnostic Molecular Pathology

Volumn 6, Issue 4, 1997, Pages 229-237

  Mansukhani, Mahesh M ^a   Nastiuk, Kent L ^a   Hibshoosh, Hanina ^a   Kularatne, Piyumika ^a   Russo, Donna ^a   Krolewski, John J ^a  

^a The New York Presbyterian Hospital   (United States)

Author keywords

BRCA1 185delAG, BRCA2 6174delT; Breast cancer; Cancer predisposition; Heteroduplex analysis; Mutation detection; PCR

Indexed keywords

HETERODUPLEX;

ALLELE; ARTICLE; BREAST CANCER; CANCER SUSCEPTIBILITY; DNA DETERMINATION; FEMALE; GENE DELETION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; JEW; ONCOGENE; OVARY CANCER; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK ASSESSMENT;

ALLELES; BRCA2 PROTEIN; BREAST NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENE AMPLIFICATION; GENES, BRCA1; HUMANS; LOSS OF HETEROZYGOSITY; MICROSCOPY, FLUORESCENCE; MUTATION; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION FACTORS;

EID: 0031444211     PISSN: 10529551     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019606-199708000-00007     Document Type: Article

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