Regulation of apoptosis by integrin receptors

Journal of Pediatric Hematology/Oncology

Volumn 19, Issue 6, 1997, Pages 541-545

  Malik, Rajesh K ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN;

ANCHORAGE INDEPENDENT GROWTH; APOPTOSIS; BINDING AFFINITY; CELL DEATH; CELL INTERACTION; CELL SURVIVAL; CELL TRANSFORMATION; CELL TYPE; EXTRACELLULAR MATRIX; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; HUMANS; INTEGRINS;

EID: 0031406579     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-199711000-00013     Document Type: Review

References (53)

1. Desimone DW. Adhesion and matrix in vertebrate development. Curr Opin Cell Biol 1994;6:747-51.
2. Meredith JE Jr, Fazeli B, Schwartz MA. The extracellular matrix as a cell survival factor. Mol Biol Cell 1993;4:953-61.
3. Frisch SM, Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 1994;124:619-26.
4. Stetler-Stevenson WG, Aznavoorian S, Liotta L. Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu Rev Cell Biol 1993;9:541-73.
5. Martins LM, Earnshaw WC. Apoptosis - alive and kicking in 1997. Trends Cell Biol 1997;7:111-4.
6. Nagata S. Apoptosis by death factor. Cell 1997;88:355-365.
7. Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-31.
8. Franke TF, Kaplan DR, and Cantley LC. PI-3K: Downstream AKTion blocks apoptosis. Cell 1997;88:435-7.
9. Reed JC, Miyashita T, Takayama S, et al. Bcl-2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy. J Cell Biochem 1996;60:23-32.
10. Dixit VM. Role of ICE-proteases in apoptosis. Adv Exp Med Biol 1996;406:113-7.
11. Hannun YA. Functions of ceramide in coordinating cellular responses to stress. Science 1996;274:1855-9.
12. Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992;69:11-25.
13. Turner CE, Burridge K. Transmembrane molecular assemblies in cell-extracellular matrix interactions. Curr Opin Cell Biol 1991;3:849-853.
14. Clark EA, Brugge JS. Integrins and signal transduction pathways:the road taken. Science 1995;268:233-9.
15. FAK, a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc Natl Acad Sci USA 1992;89:5192-6.
16. Schaller MD, Parsons JT. Focal adhesion kinase and associated proteins. Curr Opin Cell Biol 1994;6:705-10.
17. 2+-induced regulation of ion channel and MAP kinase functions. Nature 1995;376:737-45.
18. Sasaki H, Nagura K, Ishino M, et al. Cloning and characterization of cell adhesion kinase, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily. J Biol Chem 1995;270:21206-19.
19. FAK and paxillin bind to peptides mimicking beta integrin cytoplasmic domains. J Cell Biol 1995;130:1181-7.
20. src. Mol Cell Biol 1994;14:1680-8.
21. FAK. Mol Cell Biol 1994;14:147-55.
22. Schlaepfer DD, Hanks SK, Hunter T, et al. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 1994;372:786-91.
23. FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol Cell Biol 1995;15:2635-45.
24. FAK to cellular focal adhesions. J Cell Biol 1993;123:993-1005.
25. Hildebrand JD, Schaller MD, Parsons JT. Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase. Mol Biol Cell 1995;6:637-17.
26. Harte MT, Hildebrand JD, Burnham MR, et al. p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase. J Biol Chem 1996;271:13649-55.
27. Hildebrand JD, Taylor JM, Parsons JT. An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Mol Cell Biol 1996;16:3169-78.
28. Chen HC, Guan J-L. Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 1994;91:10148-52.
29. Wyllie AH, Kerr JFR, Currie AR. Cell death:the significance of apoptosis. Int Rev Cytol 1980;68:251-306.
30. Howlett AR, Bailey N, Damsky C, et al. Cellular growth and survival are mediated by β1 integrins in normal human breast epithelium but not in breast carcinoma. J Cell Sci 1995;108:1945-57.
31. Aoshiba K, Rennard SI, Spurzem JR. Cell-matrix and cell-cell interactions modulate apoptosis of bronchial epithelial cells. Am J Physiol 1997;16:L28-L37.
32. Ropke C, Gladstone P, Nielsen M, et al. Apoptosis following interleukin-2 withdrawal from T cells: evidence for a regulatory role of CD18 (beta 2-integrin) molecules. Tissue Antigens 1996;48:127-35.
33. Watson WG, Rotstein OD, Nathens AB, et al. Neutrophil apoptosis is modulated by endothelial transmigration and adhesion molecule engagement. J Immunol 1997;158:945-53.
34. + T cell growth and apoptosis. J Immunol 1996;157:2916-23.
35. Ng TTC, Kanner SB, Humphries MJ, et al. The integrin-triggered rescue of T lymphocyte apoptosis is blocked in HIV-1-infected individuals. J Immunol 1997;158:2984-99.
36. Hoyt DG, Rusnak JM, Mannix RJ, et al. Integrin activation suppresses etoposide-induced DNA strand breakage in cultured murinc tumor-derived endothelial cells. Cancer Res 1996;56:4146-9.
37. Obrien V, Frisch SM, Juliano RL. Expression of the integrin alpha-5 subunit in HT29 colon carcinoma cells suppresses apoptosis triggered by serum deprivation. Exp Cell Res 1996;224:208-13.
38. Strater J, Wedding U, Barth TFE, et al. Rapid onset of apoptosis in vitro follows disruption of beta 1-integrin/matrix interactions in human colonic crypt cells. Gastroeneterology 1996;110:1776-84.
39. Saelman EUM, Keely PJ, Santorr SA. Loss of MDCK cell α2β1 integrin expression results in reduced cyst formation, failure of hepatocyte growth factor/scatter factor-induced branching morphogenesis, and increased apoptosis. J Cell Sci 1995;108:3531-40.
40. Montgomery AMP, Reisfeld RA, Cheresh DA. Integrin αvβ3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci USA 1994;91:8856-60.
41. Brooks PC, Montgomery AMP, Rosenfeid M, et al. Integrin alpha v, beta 3 antogonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994;79:1157-64.
42. Wary KK, Mainiero F, Isakoff SJ, et al. The adaptor protein She couples a class of integrins to the control of cell cycle progression. Cell 1996;87:733-43.
43. Frisch SM, Vuori K, Ruoslahti E, et al. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 1996;134:793-9.
44. Hungerford JE, Compton MT, Matter ML, et al. Inhibition of pp125(FAK) in cultured fibroblasts results in apoptosis. J Cell Biol 1996;135:1383-90.
45. Xu L-H, Owens LV, Sturge GC, et al. Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells. Cell Growth Differ 1996;7:413-8.
46. FAK during c-Myc-induced apoptosis is suppressed by integrin signalling. Oncogene 1996;12: 2689-96.
47. Zhang Z, Vuori K, Reed JC, et al. The α5β1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. Proc Natl Acad Sci USA 1995;92:6161-5.
48. Boudreau N, Sympson CJ, Werb Z, et al. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 1995;267:891-3.
49. WAF1/CIP1 expression by vascular cell integrin αvβ3 during angiogenesis. J Clin Invest 1996;98:426-33.
50. Xia Z, Dickens M, Raingeaud J, et al. Opposing Effect of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995;270: 1326-31.
51. Westwick JK, Bielawska AE, Dbaibo G, et al. Ceramide activates the stress-activated protein kinases. J Biol Chem 1995;270:22689-92.
52. Frisch SM, Vuori K, Kelaita D, et al. A role for Jun-N-terminal kinase in anoikis: suppression by Bcl-2 and crmA. J Cell Biol 1996;135:1377-82.
53. Khwaja A, Rodriguez-Viciana P, Wennstrom S, et al. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J 1997;16:2783-93.