Fas Ligand Expression and Function in Systemic Lupus Erythematosus

Journal of Immunology

Volumn 159, Issue 9, 1997, Pages 4628-4636

  McNally, Jeremy ^a   Yoo, Dae Hyun ^a,c   Drappa, Jörn ^a   Chu, Jai Li ^a   Yagita, Hideo ^b   Friedman, Steven M ^a   Elkon, Keith B ^d  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b JUNTENDO UNIVERSITY   (Japan)

^c Hanyang University   (South Korea)

^d HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; FASL PROTEIN, MOUSE; FASLG PROTEIN, HUMAN; MEMBRANE PROTEIN;

ANIMAL; ARTICLE; CD4+ T LYMPHOCYTE; CELL LINE; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MOUSE; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; FAS LIGAND PROTEIN; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE;

EID: 0031278436     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Suda, T., T. Okazaki, Y. Naito, T. Yokota, N. Arai, S. Ozaki, K. Nakao, and S. Nagata. 1995. Expression of the Fas ligand in cells of T cell lineage. J. Immunol. 154:3806.
2. Castro, J. E., J. A. Listman, B. A. Jacobson, Y. Wang, P. A. Lopez, S. Ju, P. W. Finn, and D. L. Perkins. 1996. Fas modulation of apoptosis during negative selection of thymocytes. Immunity 5:617.
3. Griffith, T. S., T. Brunner, S. M. Fletcher, D. R. Green, and T. A. Ferguson. 1995. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270: 1189.
4. Via, C. S., P. Nguyen, A. Shustov, J. Drappa, and K. B. Elkon. 1996. A major role for the Fas pathway in lymphoid depletion in acute graft versus host disease. J. Immunol. 157:5387.
5. Nagata, S. 1996. Fas ligand and immune evasion. Nat. Med. 2:1306.
6. Nagata, S., and P. Golstein. 1995. The Fas death factor. Science 267:1449.
7. Russell, J. H., B. Rush, C. Weaver, and R. Wang. 1993. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc. Natl. Acad. Sci. USA 90:4409.
8. Singer, G. G., and A. K. Abbas. 1994. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1:365.
9. Elkon, K. B., and A. Marshak-Rothstein. 1996. B cells in systemic autoimmune disease: recent insights from Fas-deficient mice and men. Curr. Opin. Immunol. 8:852.
10. Ashany, D., X. Song, E. Lacy, J. Nikolik-Zugic, S. M. Friedman, and K. B. Elkon. 1995. Lymphocytes delete activated macrophages through the Fas/ APO-1 pathway. Proc. Natl. Acad. Sci. USA 92:11225.
11. + T cells. Nature 376:181.
12. Rathmell, J. C., S. E. Townsend, J. C. Xu, R. A. Flavell, and C. C. Goodnow. 1996. Expansion or elimination of B cells in vivo: dual roles for CD40-and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 57:319.
13. Fisher, G. H., F. J. Rosenberg, S. E. Straus, J. K. Dale, L. A. Middelton, A. Y. Lin, W. Strober, M. J. Lenardo, and J. M. Puck. 1995. Dominant interfering Fas gene mutations impair apoptosis in a human lymphoproliferative syndrome. Cell 81:935.
14. Rieuv-Laucat, F., F. Le Deist, C. Hivroz, I. A. G. Roberts, K. M. Debatin, A. Fischer, and J. P. de Villartay. 1945. Mutations in Fas associated with human lymphoproliterative syndrome and autoimmunity. Science 268:1347.
15. Drappa, J., A. K. Vaishnaw, K. E. Sullivan, J. L. Chu, and K. B. Elkon. 1996. The Canale Smith syndrome: an inherited autoimmune disorder associated with detective lymphocyte apoptosis and mutations in the Fas gene. N. Engl. J. Med. 335:1643.
16. Wu, J., J. Wilson, J. He, L. Xiang, P. H. Schur, and J. D. Mountz. 1996. Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. J. Clin. Invest. 98:1107.
17. Stohl, W. 1995. Impaired polyclonal T cell cytolytic activity: a possible risk factor for systemic lupus erythematosus. Arthritis Rheum. 38:506.
18. Tan, E. M., A. S. Cohen, J. P. Fries, A. T. Masi, D. J. McShane, N. F. Rothfield, J. G. Schaller, N. Talal, and R. J. Winchester. 1982. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25:1271.
19. Arnett, F. C., S. M. Edsworth, D. A. Bloch, D. J. McShane, J. F. Fries, N. S. Cooper, L. A. Healey, S. R. Kaplan, M. H. Liang, H. S. Luthra, T. A. Medsger, Jr., and D. M. Mitchell. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31:315.
20. Bombardier, C., D. Gladman, M. Urowitz, D. Caron, C. Chang, and the Committee on Prognosis Studies in SLE. 1992. Derivation of the SLEDAI: a disease activity index for lupus patients. Arthritis Rheum. 35:630.
21. Mysler, E., P. Bini, J. Drappa, P. Ramos, S. M. Friedman, P. H. Krammer, and K. B. Elkon. 1994. The APO-1/Fas protein in human systemic lupus erythematosus. J. Clin. Invest. 93:1029.
22. Kayagaki, N., A. Kawasaki, T. Ebata, T. Ohmoto, S. Ikeda, S. Inoue, K. Yoshino, and H. Yagita. 1995. Metalloproteinase mediated release of human Fas ligand. J. Exp. Med. 182:1777.
23. + T cells correlates with CD4 counts and clinical stage of disease. Clin. Exp. Imnumol. 97:68.
24. Schattner, E., K. B. Elkon, D. H. Yoo, J. Tumang, M. K. Crow, and S. M. Friedman. 1995. CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway. J. Exp. Med. 182:1557.
25. Walsh, C. M., A. A. Glass, V. Chiu, and W. R. Clark. 1994. The role of the Fas lytic pathway in a perforin-less CTL hybridoma. J. Immunol. 153:2506.
26. Kataoka, T., N. Shinohara, H. Takayama, K. Takaku, S. Kondo, S. Yonehara, and K. Nagai. 3996. Concanamycin A, a powerful tool for characterization and estimation of contribution of perform-and Fas-based lytic pathways in cell-mediated cytotoxicity. J. Immunol. 156:3678.
27. Stohl, W. 1992. Impaired generation of polyclonal T cell-mediated cytolytic activity despite normal polyclonal T cell proliferation in systemic lupus erythematosus. Clin. Immunol. Immunopathol. 63:163.
28. Zheng, L., G. Fisher, R. E. Miller, J. Peschon, D. H. Lynch, and M. J. Lenardo. 1995. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature 377:348.
29. Rensing-Ehl, A., K. Frei, R. Flury, B. Matiba, S. M. Mariani, M. Weller, P. Aebischer, P. H. Krammer, and A. Fontana. 1995. Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo. Eur. J. Immunol. 25:2253.
30. Tanaka, M., T. Suda, K. Haze, N. Nakamura, K. Sato, F. Kimura, K. Motoyoshi, M. Mizuki, S. Tagawa, S. Ohga, K. Hatake, A. H. Drummond, and S. Nagata. 1996. Fas ligand in human serum. Nat. Med. 2:317.
31. Cohen, P. L., and R. A. Eisenberg. 1991. lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 9:243.
32. Desai-Mehta, A., L. Lu, R. Ramsey-Goldman, and S. K. Datta. 1996. Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production. J. Clin. Invest. 97:2063.
33. Koshy, M., D. Berger, and M. K. Crow. 1996. Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes. J. Clin. Invest. 98:826.
34. + T and non-T cells in systemic lupus erythematosus following in vitro polyclonal T cell stimulation. Arthritis Rheum. 39:1840.
35. Llorente, L., W. Zou, Y. Levy, Y. Richaud-Patin, J. Wijdenes, J. Alcocer-Varela, B. Morel-Fourrier, J.-C. Brouet, D. Alarcon-Segovia, P. Galanaud, and D. Emilie. 1995. Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus. J. Exp. Med. 181:839.
36. Gourley, M. F., S. Lee, and D. K. Klinman. 1996. Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of interleukin-10: interferon-gamma-secreting cells in the peripheral blood. Arthritis Rheum. 39:379.
37. Dayal, A. K., and G. M. Kammer. 1996. The T cell enigma in lupus. Arthritis Rheum. 39:23.
38. Tsokos, G. C., B. Kovacs, P. P. Sfikakis, S. Theocharis, S. Vogelgesang, and C. S. Via. 1996. Defective antigen-presenting cell function in patients with systemic lupus erythematosus. Arthritis Rheum. 39:600.
39. Garcia-Cozar, F. J., I. J. Molina, M. J. Cuadrado, M. Marubayashi, J. Pena, and M. Santamaria. 1996. Defective B7 expression on antigen-presenting cells underlying T cell activation abnormalities in systemic lupus erythematosus (SLE) patients. Clin. Exp. Immunol. 104:72.
40. Marrack, P., and J. Kappler. 1990. The staphylococcal enterotoxins and their relatives. Science 248:705.
41. Kayagaki, N., N. Yamaguchi, F. Nagao, S. Matsuo, H. Maeda, K. Okumura, and H. Yagita. 1997. Polymorphism of murine fas ligand that affects the biological activity. Proc. Natl. Acad. Sci. USA 94:3914.