Localization and expression analysis of a novel conserved brain expressed transcript, Brx/BRX, lying within the Xic/XIC candidate region

Mammalian Genome

Volumn 8, Issue 10, 1997, Pages 760-766

  Simmler, Marie Christine ^a,c   Heard, Edith ^a   Rougeulle, Claire ^a   Cruaud, Corinne ^b   Weissenbach, Jean ^b   Avner, Philip ^a  

^a INSTITUT PASTEUR   (France)

^b GÉNÉTHON   (France)

^c ECOLE NATIONALE VÉTÉRINAIRE D ALFORT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; RODENTIA;

EID: 0031259838     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900561     Document Type: Article

References (31)

1. Aaronson JS, Eckman B, Blevins RA, Borkowski JA, Myerson J, Imran S, Elliston KO (1996) Toward the development of a gene index to the human genome: an assessment of the nature of high-throughput EST sequence data. Genome Res 6, 829-845
2. Bione S, Tamanini F, Maestrini E, Tribioli C, Poustka A, Torri G, Rivella S, Toniolo D (1993) Transcriptional organization of a 450-kb region of the human X chromosome in Xq28. Proc Natl Acad Sci USA 90, 10977-10981
3. Bonaldo MF, Lennon G, Soares MB (1996) Normalization and subtraction: two approaches to facilitate gene discovery. Genome Res 6, 791-806
4. Borsani B, Tonlorenzi R, Simmler M-C, Dandolo L, Arnaud D, Capra V, Grompe M, Pizzuti A, Muzni D, Lawrence C, Willard HF, Avner P, Ballabio A (1991) Characterization of a murine gene expressed from the inactive X chromosome. Nature 351, 325-329
5. Brockdorff N, Ashworth A, Kay GF, Cooper P, Smith S, McCabe VM, Norris DP, Penny GD, Patel D. Rastan S (1991) Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome. Nature 351, 329-331
6. Brown CJ, Lafrenière RG, Powers VE, Sebastio G, Ballabio A, Pettigrew AL, Ledbetter DH, Levy E, Craig IW, Willard HF (1991) Localization of the X inactivation centre on the human X chromosome in Xq13. Nature 349, 82-84
7. Chambers DM, Abbott CM (1996) Isolation and mapping of novel mouse brain cDNA clones containing trinucleotide repeats and demonstration of novel alleles in recombinant inbred strains. Genome Res 6, 715-723
8. Charlesworth B, Sniegowski P, Stephan W (1994) The evolutionary dynamics of repetitive DNA in eukaryotes. Nature 371, 215-220
9. Chen EY, Zollo M, Mazzarella R, Ciccodicola A, Chen C, Zuo L, Heiner C, Burough F, Repetto M, Schlessinger D, D'Urso M (1996) Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci. Hum Mol Genet 5, 659-668
10. Church GM, Gilbert W (1984) Genomic sequencing. Proc Natl Acad Sci USA 81, 1991-1995
11. Fahrner K, Hogan BLM, Flavell RA (1987) Transcription of H-2 and Qa genes in embryonic and adult mice. EMBO J 6, 1265-1271
12. Gibbons RJ, Picketts DJ, Higgs DR (1996) Syndromal mental retardation due to mutations in a regulator of gene expression. Hum Mol Genet 4, 1705-1709
13. Heard E, Avner P, Rothstein R (1994) Creation of a deletion series of mouse YACs covering a 500 kb region around Xist. Nucleic Acids Res 22, 1830-1837
14. Hieter P, Bassett EB, Valle D (1996) The yeast genome - a common currency. Nature Genet 13, 253-254
15. Hillier L, Lennon G, Becker M, Bonaldo MF, Chiapelli B, Chissoe S, Dietrich N, DuBuque T, Favello A, Gish W, Hawkins M, Hultman M, Kucaba T, Lacy M, Le N, Le Mardis E, Moore B, Morris M, Parsons J, Prange C, Rifkin L, Rohlfing T, Schellenberg K, Soares MB, Tan F, Thierry-Mieg J, Trevaskis E, Underwood K, Wohldman P, Waterston R, Wilson R, Marra M (1996) Generation and analysis of 280,000 human Expressed Sequence Tags. Genome Res 6, 807-828
16. Horn JH, Ashworth A (1995) A member of the Caudal family homeobox genes maps to the X-inactivation centre region of the mouse and human X chromosomes. Hum Mol Genet 4, 1041-1047
17. Lafrenière RG, Brown CJ, Rider S, Chelly J, Taillon-Miller P, Chinault AC, Monaco AP, Willard HF (1993) A 2.6 Mb YAC contig of the human X inactivation center region in Xq13: physical linkage of the RPS4X, PHKA1, XIST and DXS128E genes. Hum Mol Genet 2, 1105-1115
18. Lee JT, Strauss WM, Dausman JA, Jaenisch R (1996) A 450kb transgene displays properties of the mammalian X-inactivation center. Cell 86, 83-94
19. Lennon G, Auffray C, Polymeropoulos M, Soares MB (1996) The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. Genomics 33, 151-152
20. Leppig KA, Brown CJ, Bressler SL, Gustashaw K, Pagon RA, Willard HF, Disteche CM (1993) Mapping of the distal boundary of the X-inactivation center in a rearranged X chromosome from a female expressing XIST. Hum Mol Genet 2, 883-887
21. Lyon MF (1992) Some milestones in the history of X-chromosome inactivation. Annu Rev Genet 26, 17-28
22. Lyon MF, Rastan S, Brown SDM (1996) Chromosomal variants. In Genetics Variants and Strains of the Laboratory Mouse, (Oxford: Oxford University Press) Vol 2 pp 1452-1511
23. Marahrens Y, Panning B, Dausman J, Strauss W, Jaenish R (1997) Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev 11, 156-166
24. Mitchell MJ, Woods DR, Tucker PK, Opp JS, Bishop CE (1991) Homology of a candidate spermatogenic gene from the mouse Y chromosome to the ubiquitin-activating enzyme E1. Nature 354, 483-486
25. Neri G, Chiurazzi P, Arena JF, Lubs HA (1994) XLMR genes: update 1994. Am J Med Genet 51, 542-549
26. Penny GG, Kay GF, Sheardown SA, Rastan S, Brockdorff N (1996) Requirement for Xist in X chromosome inactivation. Nature 379, 131-137
27. Rougeulle C, Avner P (1996) Cloning and characterization of a murine brain specific gene Bpx and its human homologue within the Xic candidate region. Hum Mol Genet 5, 41-49
28. Rougeulle C, Colleaux L, Dujon B, Avner P (1994) Generation and characterization of an ordered lambda clone array for the 460kb region surrounding the murine Xist sequence. Mamm Genome 5, 416-423
29. Schwartz CE (1993) Invited editorial: X-linked mental retardation: in pursuit of a gene map. Am J Hum Genet 52, 1025-1031
30. Simmler MC, Cunningham DB, Clerc P, Vermat T, Caudron B, Cruaud C, Pawlak A, Szpirer C, Weissenbach J, Claverie JM, Avner P (1996) A 94kb genomic sequence 3′ to the murine Xist gene reveals an AT rich region containing a new testis specific gene Tsx. Hum Mol Genet 5, 1713-1726
31. Xu Y, Mural RJ, Uberbacher EC (1994) Constructing gene models from accurately-predicted exons: an application of dynamic programming. Comp Appl Biosci 10, 613-623