Cloning and characterization of a murine brain specific gene Bpx and its human homologue lying within the Xic candidate region

Human Molecular Genetics

Volumn 5, Issue 1, 1996, Pages 41-49

  Rougeulle, Claire ^a   Avner, Philip ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; CIS ACTING ELEMENT;

ANIMAL TISSUE; ARTICLE; CENTROMERE; CHROMOSOME XQ; GENETIC CONSERVATION; HUMAN; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; X CHROMOSOME INACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BRAIN CHEMISTRY; CHROMOSOME MAPPING; CLONING, MOLECULAR; DOSAGE COMPENSATION, GENETIC; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES; HOMEODOMAIN PROTEINS; HUMANS; MALE; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; RNA, MESSENGER; RNA, UNTRANSLATED; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSCRIPTION FACTORS; X CHROMOSOME;

ANIMALIA; MURINAE;

EID: 0030049413     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/5.1.41     Document Type: Article

References (38)

1. Rastan, S. (1994) X chromosome inactivation and the Xist gene. Curr. Opin. Genet. Dev , 4, 292-297.
2. Russell, L.B. (1983) X-autosome translocations in the mouse. Their characterization and use as tools to investigate gene inactivation and gene action. In Sandberg A.A. (ed.) Cytogenetics of the Mammalian X Chromosome, Part A: Basic Mechanisms of X Chromosome Behaviour. A.R. Lass, New York, pp. 205-250
3. Therman, E. and Sarto, G.E. (1983) Inactivation centre on the human X chromosome. In Sandberg A.A. (ed.) Cytogenetics of the Mammalian X Chromosome, Part A: Basic Mechanisms of X Chromosome Behaviour. A.R. Liss, New York, 315-325.
4. Lyon, M.F , Searle, A.G., Ford, C.E. and Ohno, S. (1964) A mouse translocation suppressing sex-linked variegation. Cytogenetics, 3, 306-323.
5. Rastan, S. and Robertson, E.J. (1985) X-chromosome deletions in embryo-derived (EK) cell lines associated with lack of X-chromosome inactivation. J. Embryol. Exp. Morph., 90, 379-388.
6. Brown, C.J., Lafreniere, R.G., Powers, V.E., Sebastio, G., Ballabio, A., Pettigrew, A.L., Ledbetter, D.H., Levy, E., Craig, I.W. and Willard H.F (1991) Localization of the X inactivation centre on the human X chromosome in Xq13. Nature, 349, 82-84.
7. Leppig, K.A., Brown, C.J., Bressler, S.L., Gustashaw, K., Pagon, R.A., Willard, H.F. and Disteche, C.M. (1993) Mapping of the distal boundary of the X-inactivation center in a rearranged X chromosome from a female expressing XIST. Hum. Mol. Genet., 2, 883-887.
8. Brown, S.D.M. (1991) The X-inactivation center and mapping of the mouse X chromosome. Genome Anal , 2, 73-97.
9. Lafrenière, R.G., Carrel, L. and Willard, H.F. (1994) A novel transmembrane transporter encoded by the XPCT gene in Xq13.2. Hum. Mol. Genet., 3, 1133-1139.
10. Brown, C.J., Ballabio, A., Rupert, J.L., Lafrenière, R.G., Grompe, M., Tonlorenzi, R. and Willard, H.F. (1991) A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature, 349, 38-44.
11. Brockdorff, N., Ashworth, A., Kay, G.F., Cooper, P., Smith, S., McCabe, V.M., Norris, D.P., Penny, G.D., Patel, D. and Rastan, S. (1991) Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome. Nature, 351, 329-331.
12. Borsani, B., Tonlorenzi, R., Simmler, M.-C., Daodolo, L., Arnaud, D., Capra, V , Grompe, M., Pizzuti, A., Muzni, D., Lawrence, C., Willard, H.F., Avner, P. and Ballabio, A. (1991) Characterization of a murine gene expressed from the inactive X chromosome Nature, 351, 325-329.
13. Brockdorff, N., Ashworth, A., Kay, G.F., McCabe, V.M., Norris, D.P., Cooper, P.J., Swift, S. and Rastan, S. (1992) The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell, 71, 515-526.
14. Brown, C J., Hendrich, B.D., Rupert, J L., Lafrenière, R.G., Xing, Y., Lawrence, R.G. and Willard, H.F. (1992) The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell, 71, 527-542.
15. Kay, G.F., Penny, G.D., Patel, D., Ashworth, A., Brockdorff, N. and Rastan, S. (1993) Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation. Cell, 72, 171-182.
16. Horn, J. H. and Ashworth, A. (1995) A member of the Caudal family homeobox genes maps to the X-inactivation centre region of the mouse and human X chromosomes. Hum. Mol. Genet., 4, 1041-1047.
17. Rougeulle, C., Colleaux, L., Dujon, B. and Avner, P. (1994) Generation and characterisation of an ordered lambda clone array for the 460 kb region surrounding the murine Xist sequence. Mammal. Genome, 5, 416-423.
18. Kozak, M. (1984) Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res., 12, 857-872.
19. Heard, E., Simmler, M.-C., Larin, Z., Rougeulle, C., Courtier, B., Lehrach, H. and Avner, P. (1993) Physical mapping and YAC contig analysis of the region surrounding Xist on the mouse X chromosome. Genomics, 15, 559-569.
20. Simon, H.-U., Mills, G.B., Kozlowski, M., Hogg, D., Branch, D., Ishimi, Y. and Siminovitch, K.A. (1994) Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation. Biochem. J., 297, 389-397.
21. Kato, K. (1990) A collection of cDNA clones with specific expression patterns in mouse brain. Eur. J. Neurosci., 2, 704-711.
22. Ishimi, Y. and Kikuchi, A. (1991) Identification and molecular cloning of yeast homolog of nucleosome assembly protein I which facilitates nucleosome assembly in vitro. J. Biol. Chem., 266, 7025-7029.
23. Schmidt-Zachmann, M.S., Hügle-Dörr, B. and Franke, W.W. (1987) A constitutive nucleolar protein identified as a member of the nucleopasmin family. EMBO J., 6, 1881-1890.
24. Dingwall, C. and Laskey, R. A. (1991) Nuclear targeting sequences-a consensus? Trends BioSci., 16, 478-481.
25. Caput, D., Beutler, B., Hartog, K., Thayer, R., Brown-Shimer, S. and Cerami, A. (1986) Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl Acad. Sci. USA, 83, 1670-1674.
26. Agulnik, A.I., Mitchell, M.J., Mattei, M.-G., Borsani, G., Avner, P.R., Lerner, J.L. and Bishop, C.E. (1994) A novel X gene with a widely transcribed Y homologue escapes X-inactivation in mouse and human. Hum. Mol. Genet., 3, 879-884.
27. Lafreniere, R.G., Brown, C.J., Rider, S., Chelly, J., Taillon-Miller, P., Chinault, A.C., Monaco, A.P. and Willard, H.F. (1993) 2.6 Mb YAC contig of the human X inactivation center region in Xq13: physical linkage of the RPS4X, PHKA1, XIST and DXS128E genes. Hum. Mol. Genet., 2, 1105-1115.
28. Torres, M. and Sanchez, L. (1989) The scute (T4) gene acts as a numerator element of the X:A signal that determines the state of activity of Sex-lethal in Drosophila. EMBO J., 8, 3079-3086.
29. Cline, T.W. (1993) The Drosophila sex determination signal: how does flies count to two. Trends Genet., 9, 385-390.
30. Douville, P.J., Atanasoski, S., Tobler, A., Fontana, A. and Schwab, M.E. (1994) The brain-specific POU-box gene Brn4 is a sex-linked transcription factor located on the human and mouse X chromosomes. Mammal. Genome, 5, 180-182.
31. Shashidharan, P., Michaelidis, T.M., Robakis, N.K., Kresoval, A., Papamatheakis, J. and Plaitakis, A. (1994) Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene. J. Biol. Chem., 269, 16 971-16 976.
32. Sargent, C.A., Young, C., Marsh, S., Ferguson-Smith, M.A. and Affara, N.A. (1994) The glycerol kinase gene family: structure of the Xp gene and related intronless retroposons. Hum. Mol. Genet., 3, 5317-1324.
33. Robertson, N G., Pomponio, R.J., Mutter, G.L. and Morton, C.C. (1991) Testis-specific expression of the human MYCL2 gene Nucleic Acids Res., 19, 3129-3137.
34. Gecz, J., Pollard, H., Consalez, G., Villard, L., Stayton, C., Millasseau, P., Khrestchatisky, M and Fontes, M. (1994) Cloning and expression of the murine homologue of a putative human X-linked nuclear protein gene closely linked to PGK1 in Xq13.3. Hum. Mol. Genet., 3, 39-44.
35. Schwartz, C.E. (1993) Invited editorial: X-linked mental retardation: in pursuit of a gene map. Am. J. Hum. Genet., 52, 1025-1031.
36. Feinberg, A.P and Vogelstein, B. (1983) A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem., 132, 6-13.
37. Church, G.M. and Gilbert, W. (1984) Genomic sequencing. Proc. Natl Acad. Sci. USA, 81, 1991-1995.
38. Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.