Genetics of APL and the molecular basis of retinoic acid treatment

International Journal of Cancer

Volumn 70, Issue 4, 1997, Pages 473-474

  Casini, Tullia ^a   Grignani, Francesco ^b   Pelicci, Pier G ^a,b  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b Policlinico Monieluce   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOIC ACID;

ACUTE MYELOBLASTIC LEUKEMIA; ARTICLE; HUMAN; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; DOWN-REGULATION; LEUKEMIA, PROMYELOCYTIC, ACUTE; NEOPLASM PROTEINS; NUCLEAR PROTEINS; ONCOGENE PROTEINS, FUSION; RECEPTORS, RETINOIC ACID; TRANSCRIPTION FACTORS; TRETINOIN; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0031025630     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970207)70:4<473::AID-IJC17>3.0.CO;2-G     Document Type: Article

References (22)

1. CHELBI-ALIX, M.K., PELICANO, L., QUIGNON, F., KOKEN, M.H.M., VENTURINI, L., STADLER, M., PAVLOVIC, J., DEGOS, L. and DE THE, H., Induction of the PML protein by interferons in normal and APL cells. Leukemia, 9, 2027-2033 (1995).
2. CHEN, Z., BRAND, N.J., CHEN, A., CHEN, S.-J., TONG, J.-H., WANG, Z.-Y., WAXMAN, S. and ZELENT, A., Fusion between a novel Krüppel-like zinc-finger gene and the retinoic acid receptor-α locus due to a variant t(11;17) translocation associated with acute promyelocytic leukemia. EMBO J., 12, 1161-1167 (1993).
3. DAWSON, M.I., ELSTNER, E., KIZAKI, M., CHEN, D.-L., PAKKALA, D.-L., KERNER, B. and KOEFFLER, H.P., Myeloid differentiation mediated through retinoic acid receptor/retinoic X receptor (RXR) not RXR/RXR pathway. Blood, 84, 446-152 (1996).
4. DOUCAS, V., ISHO, A.M., ROMO, A., JUGUILON, H., WEITZMAN, M.D., EVANS, R.M. and MAUL, G.G., Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure. Genes Develop., 10, 196-207 (1996).
5. DYCK, J.A., MAUL, G.G., MILLER, W.H., JR., DON CHEN, J., KAKIZUKA, A. and EVANS, R.M., A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein. Cell. 76, 333-343 (1994).
6. EVERETT, R.D. and MAUL, G.G., HSV-1 IE protein Vmw 110 causes redistribution of PML. EMBO J., 13, 5062-5069 (1994).
7. FLENGHI, L., FAGIOLI, M., TOMASSONI, L., PILERI, S., GAMBACORTI, M., PACINI, R., GRIGNANI, FR., CASINI, T., FERRUCCI, P.F., MARTELLI, M.F., PELICCI, P.G. and FALINI, B., Characterization of a new monoclonal antibody (PG-M3) directed against the aminoterminal portion of the PML gene product: immunocytochemical evidence for high expression of PML proteins on activated macrophases, endothelial cells, and epithelia. Blood, 85, 1871-1880 (1995).
8. GRIGNANI, T. and 14 OTHERS, Effects on differentiation by the promyelocytic leukemia PML/RARα protein depend on the fusion of the PML protein-dimerization and RARα DNA binding domains. EMBO J. (1996) (In press).
9. GRIGNANI, Fr., FAGIOLI, M., ALCALAY, M., LONGO, L., PANDOLFI, P.P., DONTI, E., BIONDI, A., LO COCO, F., GRIGNANI, F. and PELICCI, P.C., Acute promyelocytic leukemia: from genetics to treatment. Blood, 83, 10-25 (1994).
10. GRIGNANI, Fr., FERRUCCI, P.P., TESTA, U., TALAMO, G., FAGIOLI, M., ALCALAY, M., MENCARELLI, A., GRIGNANI, F., PESCHLE, C., NICOLETTI, I. and PELICCI, P.G., The acute promyelocytic leukaemia specific PML/RARa fustion protein inhibits differentiation and promotes survival of myeloid precursor cells. Cell, 74, 423-431 (1993).
11. KO, L.J. and PRIVES, C., p53: puzzle and paradigm. Genes Develop., 10, 1054-1072 (1996).
12. KOKEN, M.H.M., LINARES-CRUZ, G., QUIGNON, F., VIRON, A., CHELBI-ALIX, M.K., SBCZAK-THEPOT, J., JUHLIN, L., DEGOS, I., CALVO, F. and DE THÉ, H., The PML growth-suppressor has an altered expression in human oncogenesis. Oncogene, 10, 1315-1324 (1995).
13. LAVAU, C., MARCHIO, A., FAGIOLI, M., JANSEN, J., FALINI, B., LEBON, P., GROSVELD, F., PANDOLFI, P.P., PFLICCI, P.G. and DEJEAN, A., The acute promyelocytic leukaemia-associated PML gene is induced by Interferon. Oncogene, 11, 871-876 (1995).
14. LEVINE, A.J., The tumor suppressor genes. Ann. Rev. Biochem., 62, 623-651 (1993).
15. MU, Z.-M., CHIN, K.-V., LIU, J.-H., LOZANO, G. and CHANG, K.-S., PML, a growth suppressor disrupted in acute promyelocytic leukemia. Mol. cell. Biol., 6858-6867 (1994).
16. RAELSON, J.V., NERVI, C., ROSENAUER, A., MONOZAK, Y., PEARSON, M., PELICCI, P.G. and MILLER, W.H., JR., The PML/RARα oncoprotein is a direct molecular target of retinoic acid in acute promyelocytic leukemia cells. Blood (1996) (In press).
17. REDNER, R.L., RUSH, E.A., FAAS, S., RUDERT, W.A. and COREY, S.J., The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion. Blood, 87, 882-886 (1996).
18. ROGAIA, D., GRIGNANI, F., GRIGNANI, F., NICOLETTI, I. and PELICCI, P.G., The acute promyelocytic leukemia-specific PML/RARα fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of GM-CSF-dependent myeloid cells. Leukemia, 9, 1467-1472 (1995).
19. SZEKELY, L., POKROVSKAJA, K., JIANG, W.-Q., DE THÉ, H., RINGERTW, N. and KLEIN, G., The Epstein-Barr virus-encoded nuclear antigen EBNA-5 accumulates in PML-containing bodies. J. Virol., 70, 2562-2568 (1996).
20. TERRIS, B., BALDIN, V., DUBOIS, S., DEGOTT, C., FLEJOU, J.-F., HENIN, D. and DEJEAN, A., PML nuclear bodies are general targets for inflammation and cell proliferation. Cancer Res., 55, 1590-1597 (1995).
21. TSAI, S., BARTELMEZ, S., HEYMAN, R., DAMM, K., EVANS, R. and COLLINS, S., A mutated retinoic acid receptor-α exhibiting dominant-negative activity alters the lineage development of a multipotent hematopietic cell line. Genes Develop., 6, 2258-2269 (1992).
22. WEIS, K., RAMBAUD, S., LAVAU, C., JANSEN, J., CARCALHO, T., CARMOFONSECA, M., LAMOND, A. and DEJEAN, A., Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells. Cell, 76, 345-358 (1994).