Myeloid differentiation mediated through retinoic acid receptor/retinoic X receptor (RXR) not RXR/RXR pathway

Blood

Volumn 84, Issue 2, 1994, Pages 446-452

  Dawson, Marcia I ^b   Elstner, Elena ^b   Kizaki, Masahiro ^b   Chen, Dan Lin ^b   Pakkala, Seppo ^b   Kerner, Berit ^b   Koeffler, H Phillip ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

4 [2 METHYL (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 NAPHTHALENYL) 1 PROPEN 1 YL]BENZOIC ACID; 4 [2 METHYL 1 (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 NAPHTHYL) 1 PROPENYL]BENZOIC ACID; RETINOIC ACID; RETINOIC ACID BINDING PROTEIN; RETINOID; SR 3961; TAMIBAROTENE; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN HL 60; COLONY FORMATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA; MYELOPOIESIS; PRIORITY JOURNAL; TRANSACTIVATION;

EID: 0028306799     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v84.2.446.bloodjournal842446     Document Type: Article

References (41)

1. Koeffler HP: Induction of differentiation of human acute myelogenous leukemia cells: Therapeutic implications. Blood 62:709, 1983
2. Brietman TR, Collins SJ, Keene BR: Terminal differentiation of human promyelocytic leukemia cells in primary culture in response to retinoic acid. Blood 57:1000, 1981
3. Honma Y, Fujita Y, Kasukabe T, Hozumi M, Sampi K, Sakurai M, Tsushima S, Nomura H: Induction of differentiation of human acute non-lymphocytic leukemia cells in primary culture by inducers of differentiation of human myeloid leukemia cell line HL-60. Eur J Cancer Clin Oncol 19:251, 1983
4. Douer D, Koeffler HP: Retinoic acid: Inhibition of the clonal growth of human myeloid leukemia cells. J Clin Invest 69:277, 1982
5. Flynn PJ, Miller WJ, Weisdorf DJ, Arthur D, Banning R, Branda R: Retinoic acid treatment of acute promyelocytic leukemia: In vitro and in vivo observations. Blood 62:1211, 1983
6. Nilsson B: Probable in vivo induction of differentiation by retinoic acid of promyelocytes in acute promyelocytic leukemia. Br J Haematol 57:365, 1984
7. Daenen S, Vallenga E, van Dobbenburgh OA, Halie MR: Retinoic acid as antileukemic therapy in a patient with acute promyelocytic leukemia and aspergillus pneumonia. Blood 67:559, 1986
8. Fontana JA, Rogers JS, Durham JP: The role of 13-cis-retinoic acid in the remission induction of a patient with acute promyelocytic leukemia. Cancer 57:209, 1986
9. Huang M, Ye Y, Chen S, Chai J, Lu J, Xhoa L, Gu L, Wang Z: Use of all-trans-retinoic acid in the treatment of the acute promyelocytic leukemia. Blood 72:567, 1988
10. Castaigne S, Chomienne C, Daniel MT, Ballerini P, Berger R, Fenaux P, Degos L: All-trans-retinoic acid as a differentiation therapy for acute promyelocytic leukemia: 1 Clinical results. Blood 76:1704, 1990
11. Warrell RP Jr, Frankel SR, Miller WH Jr, Scheinberg DA, Itri LM, Hittelman WN, Vyas R, Andreeff M, Tafuri A, Jakubowski A, Gabrilove J, Gordon MS, Dmitrovsky E: Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). N Engl J Med 324:1385, 1991
12. Lotan R: Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells. Biochem Biophys Acta 605:33, 1980
13. Maden M: Vitamin A and pattern formation in the regenerating limb. Nature 295:672, 1982
14. Thaller C, Eichele G: Identification and spatial distribution of retinoids in the developing chick limb bud. Nature 327:625, 1987
15. Wolbach SB, Howe PR: Tissue changes following deprivation of fat soluble A vitamin. J Exp Med 42:753, 1925
16. Hodges RE, Sauberlich HE, Canham JE, Wallace DL, Rucker RB, Mejia LA, Mohanram M: Hematopoietic studies in vitamin A deficiency. Am J Clin Nutr 31:876, 1978
17. Mejia LA, Hodges RE, Rucker RB: Clinical signs of anemia in vitamin A-deficient rats. Am J Clin Nutr 32:1439, 1979
18. Douer D, Koeffler HP: Retinoic acid enhances colony-stimulating factor-induced clonal growth of normal human myeloid progenitor cells in vitro. Exp Cell Res 138:193, 1982
19. Tobler A, Dawson MI, Koeffler HP: Retinoids: Structure-function relationship in normal and leukemic hematopoiesis in vitro. J Clin Invest 78:303, 1986
20. Chytil F, Ong DE: in Sporn MB, Roberts AB, Goodman DS (eds): The Retinoids, vol 2. New York, NY, Academic, 1984, p 89
21. Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM: A nuclear receptor that identifies a novel retinoic acid response pathway. Nature 345:224, 1990
22. Levin AA, Sturzenbecker LJ, Kazmer S, Bosakowski T, Huselton C, Allenby G, Speck J, Kratzeisen C, Rosenberger M, Lovey A, Grippo JF: 9-cis retinoic acid steroisomer binds and activates the nuclear receptor RXRβ. Nature 355:359, 1992
23. Heyman RA, Mangelsdorf DF, Dyck JA, Stein RB, Eichele G, Evans RM, Thaller C: 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell 68:397, 1992
24. Sakashita A, Kizaki M, Pakkala S, Schiller G, Pakkala S, Tsuruoka N, Toraosaki R, Dawson M, Cameron J, Koeffler HP: 9-cis-retinoic acid: Effects on normal and leukemic hematopoiesis in vitro. Blood 81:1009, 1993
25. Kizaki M, Ikeda Y, Tanosaki R, Nakajima H, Morikawa M, Sakashita A, Koeffler HP: Effects of novel retinoic acid compound, 9-cis-retinoic acid, on proliferation, differentiation, and expression of RARβ and RXRβ RNA by HL-60 cells. Blood 82:3592, 1994
26. Yu VC, Delsert C, Andersen B, Holloway JM, Devary OV, Naar AM, Kim SY, Boutin JM, Glass CK, Rosenfeld MG: RXR beta: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell 67:1251, 1991
27. Zhang XK, Hoffmann B, Tran PB, Graupner G, Pfahl M: Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature 355:441, 1992
28. Leid M, Kastner P, Lyons R, Nakshatri H, Saunders M, Zacharewski T, Chen JY, Staub A, Gamier JM, Mader S: Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell 68:377, 1992
29. 3 signalling. Nature 355:446, 1992
30. Bugge TH, Pohl J, Lonnoy O, Stunnenberg HG: RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors. EMBO J 11:1409, 1992
31. Marks MS, Hallenbeck PL, Nagata T, Segars JH, Appella E, Nikodem VM, Ozato K: H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes. EMBO J 11:1419, 1992
32. Hermann T, Hoffmann B, Zhang XK, Tran P, Pfahl M: Heterodimeric receptor complexes determine 3,5,3′-triiodothyronine and retinoid signaling specificities. Mol Endocrinol 6:1153, 1992
33. Zhang XK, Lehmann J, Hoffmann B, Dawson MI, Cameron J, Graupner G, Hermann T, Tran P, Pfahl M: Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature 358:587, 1992
34. Lehmann JM, Jong L, Fanjul A, Cameron JF, Lu XP, Haefner P, Dawson MI, Pfahl M: Retinoids selective for retinoid X receptor response pathways. Science 258:1944, 1993
35. Collins SJ, Gallo RC, Gallagher RE: Continuous growth and differentiation of human myeloid leukemic cells in suspension culture. Nature 270:347, 1977
36. Dawson MI, Hobbs PD, Derdzinski KA, Chao W, Franking G, Loew GH, Jetten AM, Napoli JL, Williams JB, Sani BP, Willer JJ Jr, Schiff LJ: Effect of structural modifications in the C7-C11 region of the retinoid skeleton on biological activity in a series of aromatic retinoids. J Med Chem 32:1504, 1989
37. Maignan J, Lang G, Malle G, Restle S, Shroot B: (CIRD). Nouveux derives bicycliques aromatiques, leur procede de preparation et leur utilization en medicine humaine et veterinaire et en cosmetique. French Patent 2,601,670, January 22, 1988
38. Munker R, Norman AW, Koeffler HP: Vitamin D compounds: Effect on clonal proliferation and differentiation of human myeloid cells. J Clin Invest 78:424, 1986
39. Chao WR, Rudd CJ, Costa E, Jong L, Hobbs PD, Lehmann JM, Pfahl M, Lombardo A, Ely KA, Quick T, Dawson MI: Effects of nuclear receptor-selective retinoids on epidermal cells in the presence of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Mechanism of Action of Retinoids, Vitamin D, and Steroid Hormones. American Association of Cancer Research, Banff, Alberta, Canada, March 15-21, 1993
40. Davies P, Nagy L, Thomazy V, Gil D, Chandraratna R: Studies on the role of retinoid receptors in the induction of gene expression, differentiation and cell death in human promyelocytic leukemic (HL-60) cells. Mechanism of Action of Retinoids, Vitamin D, and Steroid Hormones. American Association of Cancer Research, Banff, Alberta, Canada, March 15-21, 1993
41. Robertson KA, Emami B, Mueller L, Collins SJ: Multiple members of the retinoic acid receptor family are capable of mediating the granulocytic differentiation of HL-60 cells. Mol Cell Biol 3743, 1992