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Volumn 66, Issue 1, 1996, Pages 105-113

Effects of protein kinase inhibitors on morphology and function of cultured bovine adrenal chromaffin cells: KN-62 inhibits secretory function by blocking stimulated Ca2+ entry

Author keywords

Adrenal chromaffin; Ca2+ influx; H 7; H 8; K 252a; KN 62; Secretion; Staurosporine

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; K 252A; N (2 METHYLAMINOETHYL) 5 ISOQUINOLINESULFONAMIDE; STAUROSPORINE;

EID: 0030070534     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.66010105.x     Document Type: Article
Times cited : (25)

References (55)
  • 1
    • 0027763496 scopus 로고
    • Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells
    • Ammala C., Eliasson L., Bokvist K., Larsson O., Ashcroft F. M., and Rorsman P. (1993) Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells. J. Physiol. (Lond.) 472, 665-688.
    • (1993) J. Physiol. (Lond.) , vol.472 , pp. 665-688
    • Ammala, C.1    Eliasson, L.2    Bokvist, K.3    Larsson, O.4    Ashcroft, F.M.5    Rorsman, P.6
  • 3
    • 0024348376 scopus 로고
    • Astrocyte morphology altered by 1-(5-isoquinolinylsulfonyl)-2-methyl-piperazine (H-7) and other protein-kinase inhibitors
    • Bedoy C. A. and Mobley P. L. (1989) Astrocyte morphology altered by 1-(5-isoquinolinylsulfonyl)-2-methyl-piperazine (H-7) and other protein-kinase inhibitors. Brain Res. 490, 243-254.
    • (1989) Brain Res. , vol.490 , pp. 243-254
    • Bedoy, C.A.1    Mobley, P.L.2
  • 4
    • 0026512998 scopus 로고
    • K-252a inhibits nerve growth factor-induced trk proto-oncogene tyrosine phosphorylation and kinase activity
    • Berg M. M., Sternberg D. W., Parada L. F., and Chao M. V. (1992) K-252a inhibits nerve growth factor-induced trk proto-oncogene tyrosine phosphorylation and kinase activity. J. Biol. Chem. 267, 13-16.
    • (1992) J. Biol. Chem. , vol.267 , pp. 13-16
    • Berg, M.M.1    Sternberg, D.W.2    Parada, L.F.3    Chao, M.V.4
  • 5
    • 0024424008 scopus 로고
    • Protein kinase C inhibitor H-7 alters the actin cytoskeleton of cultured cells
    • Birrell G. B., Hedberg K. K., and Griffith O. H. (1989) Protein kinase C inhibitor H-7 alters the actin cytoskeleton of cultured cells. J. Cell. Physiol. 141, 74-84.
    • (1989) J. Cell. Physiol. , vol.141 , pp. 74-84
    • Birrell, G.B.1    Hedberg, K.K.2    Griffith, O.H.3
  • 6
    • 0000854861 scopus 로고
    • Growth of a rat neuroblastoma cell line in serum-free supplemented medium
    • Bottenstein J. E. and Sato G. H. (1979) Growth of a rat neuroblastoma cell line in serum-free supplemented medium. Proc. Natl. Acad. Sci. USA 76, 514-517.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 514-517
    • Bottenstein, J.E.1    Sato, G.H.2
  • 7
    • 0026665566 scopus 로고
    • Characterization of histamine-induced catecholamine secretion from bovine adrenal medullary chromaffin cells
    • Bunn S. J. and Boyd T. L. (1992) Characterization of histamine-induced catecholamine secretion from bovine adrenal medullary chromaffin cells. J. Neurochem. 58, 1602-1610.
    • (1992) J. Neurochem. , vol.58 , pp. 1602-1610
    • Bunn, S.J.1    Boyd, T.L.2
  • 8
    • 0027258953 scopus 로고
    • Regulated exocytosis
    • Burgoyne R. D. and Morgan A. (1993) Regulated exocytosis. Biochem. J. 293, 305-316.
    • (1993) Biochem. J. , vol.293 , pp. 305-316
    • Burgoyne, R.D.1    Morgan, A.2
  • 9
    • 0026445719 scopus 로고
    • Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly
    • Burridge K , Turner C. E., and Romer L. H. (1992) Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J. Cell Biol. 119, 893-903.
    • (1992) J. Cell Biol. , vol.119 , pp. 893-903
    • Burridge, K.1    Turner, C.E.2    Romer, L.H.3
  • 10
    • 0028220675 scopus 로고
    • Staurosporine, K-252a, and K-252b stabilize calcium homeostasis and promote survival of CNS neurons in the absence of glucose
    • Cheng B., Barger S. W., and Mattson M. P. (1994) Staurosporine, K-252a, and K-252b stabilize calcium homeostasis and promote survival of CNS neurons in the absence of glucose. J. Neurochem. 62, 1319-1329.
    • (1994) J. Neurochem. , vol.62 , pp. 1319-1329
    • Cheng, B.1    Barger, S.W.2    Mattson, M.P.3
  • 11
    • 0028870428 scopus 로고
    • K-252a induces tyrosine phosphorylation of the focal adhesion kinase and neurite outgrowth in human neuroblastoma SH-SY5Y cells
    • Coco Maroney A., Lipfert L., Forbes M. E., Glicksman M. A., Neff N. T., Siman R., and Dionne C. A. (1995) K-252a induces tyrosine phosphorylation of the focal adhesion kinase and neurite outgrowth in human neuroblastoma SH-SY5Y cells. J. Neurochem. 64, 540-549.
    • (1995) J. Neurochem. , vol.64 , pp. 540-549
    • Coco Maroney, A.1    Lipfert, L.2    Forbes, M.E.3    Glicksman, M.A.4    Neff, N.T.5    Siman, R.6    Dionne, C.A.7
  • 12
    • 0025335514 scopus 로고
    • Differentiation to a neuronal phenotype in bovine chromaffin cells is repressed by protein kinase C and is not dependent on c-fos oncoproteins
    • Demeneix B. A., Kley N., and Loeffler J. P. (1990) Differentiation to a neuronal phenotype in bovine chromaffin cells is repressed by protein kinase C and is not dependent on c-fos oncoproteins. DNA Cell Biol. 9, 335-345.
    • (1990) DNA Cell Biol. , vol.9 , pp. 335-345
    • Demeneix, B.A.1    Kley, N.2    Loeffler, J.P.3
  • 13
    • 0009663357 scopus 로고
    • A multiple comparison procedure for comparing several treatments with a control
    • Dunnett C. W. (1955) A multiple comparison procedure for comparing several treatments with a control. J. Am. Stat. Assoc. 50, 1096-1121.
    • (1955) J. Am. Stat. Assoc. , vol.50 , pp. 1096-1121
    • Dunnett, C.W.1
  • 14
    • 0025060837 scopus 로고
    • Regulation of the epidermal growth factor receptor by growth-modulating agents: Effects of staurosporine, a protein kinase inhibitor
    • Friedman B., Fujiki H., and Rosner M. R. (1990) Regulation of the epidermal growth factor receptor by growth-modulating agents: effects of staurosporine, a protein kinase inhibitor. Cancer Res. 50, 533-538.
    • (1990) Cancer Res. , vol.50 , pp. 533-538
    • Friedman, B.1    Fujiki, H.2    Rosner, M.R.3
  • 15
    • 0024166194 scopus 로고
    • Characterization of receptor tyrosine-speciflc protein kinases by the use of inhibitors. Staurosporine is a 100-times more potent inhibitor of insulin receptor than IGF-I receptor
    • Fujita-Yamaguchi Y. and Kathuria S. (1988) Characterization of receptor tyrosine-speciflc protein kinases by the use of inhibitors. Staurosporine is a 100-times more potent inhibitor of insulin receptor than IGF-I receptor. Biochem. Biophys. Res. Commun. 157, 955-962.
    • (1988) Biochem. Biophys. Res. Commun. , vol.157 , pp. 955-962
    • Fujita-Yamaguchi, Y.1    Kathuria, S.2
  • 16
    • 0027402975 scopus 로고
    • Synaptic vesicle phosphoproteins and regulation of synaptic function
    • Greengard P., Valtorta F., Benfenati F., and Czernik A. J. (1993) Synaptic vesicle phosphoproteins and regulation of synaptic function. Science 259, 780-785.
    • (1993) Science , vol.259 , pp. 780-785
    • Greengard, P.1    Valtorta, F.2    Benfenati, F.3    Czernik, A.J.4
  • 17
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • Hanks S. K., Quinn A. M., and Hunter T. (1988) The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 241, 42-52.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 19
    • 0025335601 scopus 로고
    • Staurosporine induces dissolution of microfilament bundles by a protein kinase C-independent pathway
    • Hedberg K. K., Birrell G. B., Habliston D. L., and Griffith O. H. (1990) Staurosporine induces dissolution of microfilament bundles by a protein kinase C-independent pathway. Exp. Cell Res. 188, 199-208.
    • (1990) Exp. Cell Res. , vol.188 , pp. 199-208
    • Hedberg, K.K.1    Birrell, G.B.2    Habliston, D.L.3    Griffith, O.H.4
  • 20
    • 0024379721 scopus 로고
    • Barium ions enter chromaffin cells via voltage-dependent calcium channels and induce secretion by a mechanism independent of calcium
    • Heldman E., Levine M., Raveh L., and Pollard H. B. (1989) Barium ions enter chromaffin cells via voltage-dependent calcium channels and induce secretion by a mechanism independent of calcium. J. Biol. Chem. 264, 7914-7920.
    • (1989) J. Biol. Chem. , vol.264 , pp. 7914-7920
    • Heldman, E.1    Levine, M.2    Raveh, L.3    Pollard, H.B.4
  • 23
    • 0026739478 scopus 로고
    • Protein kinase C and calmodulin kinase are required for endothelin-stimulated atrial natriuretic factor secretion from primary atrial myocytes
    • Irons C. E., Sei C. A., Hidaka H., and Glembotski C. C. (1992) Protein kinase C and calmodulin kinase are required for endothelin-stimulated atrial natriuretic factor secretion from primary atrial myocytes. J. Biol. Chem. 267, 5211-5216.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5211-5216
    • Irons, C.E.1    Sei, C.A.2    Hidaka, H.3    Glembotski, C.C.4
  • 25
    • 0025194852 scopus 로고
    • 2+-calmodulin-dependent protein kinase II inhibitor on GABA release in cerebrospinal fluid of the rat
    • 2+-calmodulin-dependent protein kinase II inhibitor on GABA release in cerebrospinal fluid of the rat. J. Pharmacol. Exp. Ther. 254, 598-602.
    • (1990) J. Pharmacol. Exp. Ther. , vol.254 , pp. 598-602
    • Ishikawa, N.1    Hashiba, Y.2    Hidaka, H.3
  • 26
    • 0027295172 scopus 로고
    • Stimulatory effects of protein kinase C and calmodulin kinase II on N-methyl-D-aspartate receptor/channels in the postsynaptic density of rat brain
    • Kitamura Y., Miyazaki A., Yamanaka Y., and Nomura Y. (1993) Stimulatory effects of protein kinase C and calmodulin kinase II on N-methyl-D-aspartate receptor/channels in the postsynaptic density of rat brain J. Neurochem. 61, 100-109.
    • (1993) J. Neurochem. , vol.61 , pp. 100-109
    • Kitamura, Y.1    Miyazaki, A.2    Yamanaka, Y.3    Nomura, Y.4
  • 27
    • 0026595294 scopus 로고
    • K-252 compounds: Modulators of neurotrophin signal transduction
    • Knüsel B. and Hefti F. (1992) K-252 compounds: modulators of neurotrophin signal transduction. J. Neurochem. 59, 1987-1996.
    • (1992) J. Neurochem. , vol.59 , pp. 1987-1996
    • Knüsel, B.1    Hefti, F.2
  • 28
    • 0025316036 scopus 로고
    • Antiplatelet effects of chelerythrine chloride isolated from Zanthoxylum simulans
    • Ko F. N., Chen I. S., Wu S. J., Lee L. G., Haung T. F., and Teng C. M. (1990) Antiplatelet effects of chelerythrine chloride isolated from Zanthoxylum simulans. Biochim. Biophys. Acta 1052, 360-365.
    • (1990) Biochim. Biophys. Acta , vol.1052 , pp. 360-365
    • Ko, F.N.1    Chen, I.S.2    Wu, S.J.3    Lee, L.G.4    Haung, T.F.5    Teng, C.M.6
  • 31
    • 0026761502 scopus 로고
    • Time-dependent inhibition of stimulated adrenal catecholamine release by staurosporine
    • Maurer J. A. and McKay D. B. (1992) Time-dependent inhibition of stimulated adrenal catecholamine release by staurosporine. J. Neurochem. 59, 1578-1580.
    • (1992) J. Neurochem. , vol.59 , pp. 1578-1580
    • Maurer, J.A.1    McKay, D.B.2
  • 32
    • 0027953598 scopus 로고
    • Staurosporine-induced reduction of secretory function in cultured bovine adrenal chromaffin cells
    • Maurer J. A. and McKay D. B. (1994) Staurosporine-induced reduction of secretory function in cultured bovine adrenal chromaffin cells. Eur. J. Pharmacol. 253, 115-124.
    • (1994) Eur. J. Pharmacol. , vol.253 , pp. 115-124
    • Maurer, J.A.1    McKay, D.B.2
  • 33
    • 0028981624 scopus 로고
    • Staurosporine affects calcium homeostasis in cultured bovine adrenal chromaffin cells
    • Maurer J. A., Wenger B. W., Guan Z., Stokes B. T., and McKay D. B. (1995) Staurosporine affects calcium homeostasis in cultured bovine adrenal chromaffin cells. Eur. J. Pharmacol. 288, 163-172.
    • (1995) Eur. J. Pharmacol. , vol.288 , pp. 163-172
    • Maurer, J.A.1    Wenger, B.W.2    Guan, Z.3    Stokes, B.T.4    McKay, D.B.5
  • 34
    • 0021137090 scopus 로고
    • ++ uptake and catecholamine secretion from adrenal chromaffin cells by taxol and vinblastine
    • ++ uptake and catecholamine secretion from adrenal chromaffin cells by taxol and vinblastine. J. Pharmacol. Exp. Ther. 231, 102-108.
    • (1984) J. Pharmacol. Exp. Ther. , vol.231 , pp. 102-108
    • McKay, D.B.1    Schneider, A.S.2
  • 35
    • 0024507037 scopus 로고
    • Microfilament-associated, local degranulation of rat peritoneal mast cells
    • Mio M. and Tasaka K. (1989) Microfilament-associated, local degranulation of rat peritoneal mast cells. Int. Arch. Appl Immunol. 88, 369-371.
    • (1989) Int. Arch. Appl Immunol. , vol.88 , pp. 369-371
    • Mio, M.1    Tasaka, K.2
  • 36
    • 0025026423 scopus 로고
    • 2+-dependent exocytosis in digitonin-permeabilized bovine adrenal chromaffin cells
    • 2+-dependent exocytosis in digitonin-permeabilized bovine adrenal chromaffin cells. Biochem. J. 271, 571-574.
    • (1990) Biochem. J. , vol.271 , pp. 571-574
    • Morgan, A.1    Burgoyne, R.D.2
  • 37
    • 0023258497 scopus 로고
    • Staurosporine inhibits tyrosine-specific protein kinase activity of rous sarcoma virus transforming protein p60
    • Nakano H., Kobayashi E., Takahashi I., Tamaoki T., Kuzuu Y., and Iba H. (1987) Staurosporine inhibits tyrosine-specific protein kinase activity of rous sarcoma virus transforming protein p60. J. Antibiot. (Tokyo) 40, 706-708.
    • (1987) J. Antibiot. (Tokyo) , vol.40 , pp. 706-708
    • Nakano, H.1    Kobayashi, E.2    Takahashi, I.3    Tamaoki, T.4    Kuzuu, Y.5    Iba, H.6
  • 39
    • 0027093254 scopus 로고
    • Staurosporine-induced neunte outgrowth in PC12 cells is independent of protein kinase C inhibition
    • Rasouly D., Rahamim E., Lester D., Matsuda Y., and Lazarovici P. (1992) Staurosporine-induced neunte outgrowth in PC12 cells is independent of protein kinase C inhibition. Mol. Pharmacol. 42, 35-43.
    • (1992) Mol. Pharmacol. , vol.42 , pp. 35-43
    • Rasouly, D.1    Rahamim, E.2    Lester, D.3    Matsuda, Y.4    Lazarovici, P.5
  • 40
    • 0028081945 scopus 로고
    • Neurites induced by staurosporine in PC12 cells are resistant to colchicine and express high levels of tau proteins
    • Rasouly D., Rahamim E., Ringel I., Ginzburg I., Murakata C., Matsuda Y., and Lazarovici P. (1993) Neurites induced by staurosporine in PC12 cells are resistant to colchicine and express high levels of tau proteins. Mol. Pharmacol. 45, 29-35.
    • (1993) Mol. Pharmacol. , vol.45 , pp. 29-35
    • Rasouly, D.1    Rahamim, E.2    Ringel, I.3    Ginzburg, I.4    Murakata, C.5    Matsuda, Y.6    Lazarovici, P.7
  • 41
    • 0024394417 scopus 로고
    • Staurosporine, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases
    • Rüegg U. T. and Burgess G. M. (1989) Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. Trends Pharmacol. Sci. 10, 218.
    • (1989) Trends Pharmacol. Sci. , vol.10 , pp. 218
    • Rüegg, U.T.1    Burgess, G.M.2
  • 42
    • 0022929859 scopus 로고
    • 2+ (calmodulin)-dependent protein kinase II by an autophosphorylation mechanism
    • 2+ (calmodulin)-dependent protein kinase II by an autophosphorylation mechanism. J. Biol. Chem. 261, 8581-8584.
    • (1986) J. Biol. Chem. , vol.261 , pp. 8581-8584
    • Schworer, C.M.1    Colbran, R.J.2    Soderling, T.R.3
  • 43
    • 0025194183 scopus 로고
    • 2+/phospholipid-dependent protein kinase in catecholamine secretion from bovine adrenal medullary chromaffin cells
    • 2+/phospholipid-dependent protein kinase in catecholamine secretion from bovine adrenal medullary chromaffin cells. Biochem. Pharmacol. 40, 1505-1513.
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 1505-1513
    • Tachikawa, E.1    Takahashi, S.2    Kashimoto, T.3    Kondo, Y.4
  • 45
    • 5244302264 scopus 로고
    • The role of microfilaments in the degranulation and histamine release from mast cells
    • Hatase O. and Wang J. H., eds, Elsevier Science Publishers, New York
    • Tasaka K., Mio M., and Akagi M. (1989) The role of microfilaments in the degranulation and histamine release from mast cells, in Bioinformatics: Information Transduction and Processing Systems from Cell to Whole Body (Hatase O. and Wang J. H., eds), p. 195. Elsevier Science Publishers, New York.
    • (1989) Bioinformatics: Information Transduction and Processing Systems from Cell to Whole Body , pp. 195
    • Tasaka, K.1    Mio, M.2    Akagi, M.3
  • 46
    • 0025610723 scopus 로고
    • Activation of protein kinase C is not required for exocytosis from bovine adrenal chromaffin cells
    • TerBush D. R. and Holz R. W. (1990) Activation of protein kinase C is not required for exocytosis from bovine adrenal chromaffin cells. J. Biol. Chem. 265, 21179-21184.
    • (1990) J. Biol. Chem. , vol.265 , pp. 21179-21184
    • TerBush, D.R.1    Holz, R.W.2
  • 47
    • 0025122947 scopus 로고
    • Mimicry and inhibition of nerve growth factor effects: Interactions of staurosporine, forskolin, and K252a in PC12 cells and normal rat chromaffin cells in vitro
    • Tischler A. S., Ruzicka L. A., and Perlman R. L. (1990) Mimicry and inhibition of nerve growth factor effects: interactions of staurosporine, forskolin, and K252a in PC12 cells and normal rat chromaffin cells in vitro. J. Neurochem. 55, 1159-1165.
    • (1990) J. Neurochem. , vol.55 , pp. 1159-1165
    • Tischler, A.S.1    Ruzicka, L.A.2    Perlman, R.L.3
  • 49
    • 0026583886 scopus 로고
    • Cytoskeleton and molecular mechanisms in neurotransmitter release by neurosecretory cells
    • Trifaró J.-M., Vitale M. L., and Rodriguez Del Castillo A. (1992) Cytoskeleton and molecular mechanisms in neurotransmitter release by neurosecretory cells. Eur. J. Pharmacol. 225, 83-104.
    • (1992) Eur. J. Pharmacol. , vol.225 , pp. 83-104
    • Trifaró, J.-M.1    Vitale, M.L.2    Rodriguez Del Castillo, A.3
  • 50
    • 0024455554 scopus 로고
    • Neunte outgrowth from mouse neuroblastoma and cerebellar cells induced by the protein-kinase inhibitor H-7
    • Tsuda M., Ono K., Katayama N., Yamagata Y., Kikuchi K., and Tsuchiya T. (1989) Neunte outgrowth from mouse neuroblastoma and cerebellar cells induced by the protein-kinase inhibitor H-7. Neurosci. Lett. 105, 241-245.
    • (1989) Neurosci. Lett. , vol.105 , pp. 241-245
    • Tsuda, M.1    Ono, K.2    Katayama, N.3    Yamagata, Y.4    Kikuchi, K.5    Tsuchiya, T.6
  • 52
    • 0025840196 scopus 로고
    • Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin
    • Vitale M. L., Rodriguez Del Castillo A., Tchakarov L., and Trifaró J.-M. (1991) Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin. J. Cell Biol. 113, 1057-1067.
    • (1991) J. Cell Biol. , vol.113 , pp. 1057-1067
    • Vitale, M.L.1    Rodriguez Del Castillo, A.2    Tchakarov, L.3    Trifaró, J.-M.4
  • 53
    • 0026799405 scopus 로고
    • Inactivation of the sarcoplasmic reticulum channel by protein kinase
    • Wang J. and Best P. M. (1992) Inactivation of the sarcoplasmic reticulum channel by protein kinase. Nature 359, 739-741.
    • (1992) Nature , vol.359 , pp. 739-741
    • Wang, J.1    Best, P.M.2


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