Determination of DNA sequences required for regulated Mycobacterium tuberculosis RecA expression in response to DNA-damaging agents suggests that two modes of regulation exist

Journal of Bacteriology

Volumn 179, Issue 11, 1997, Pages 3509-3518

  Movahedzadeh, Farahnaz ^a   Colston, M Joseph ^a   Davis, Elaine O ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; BINDING SITE; CONSENSUS SEQUENCE; DNA DAMAGE; DNA DETERMINATION; DNA FLANKING REGION; DNA SEQUENCE; ESCHERICHIA COLI; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE MAPPING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RECA GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; START CODON; TRANSCRIPTION INITIATION;

BACILLUS SUBTILIS; ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0030958621     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.179.11.3509-3518.1997     Document Type: Article

References (60)

1. Bashyam, M. D., D. Kaushal, S. K. Dasgupta, and A. K. Tyagi. 1996. A study of the mycobacterial transcriptional apparatus: identification of novel features in promoter elements. J. Bacteriol. 178:4847-4853.
2. Bayles, K. W., E. W. Brunskill, J. J. Iandolo, L. L. Hruska, S. Huang, P. A. Pattee, B. K. Smiley, and R. E. Yasbin. 1994. A genetic and molecular characterization of the recA gene from Staphylococcus aureus. Gene 147:13-20.
3. Bertrand-Burggraf, E., S. Hurstel, M. Daune, and M. Schnarr. 1987. Promoter properties and negative regulation of the uvrA gene by the LexA repressor and its amino-terminal DNA binding domain. J. Mol. Biol. 193: 293-302.
4. Brent, R., and M. Ptashne. 1981. Mechanism of action of the lexA gene product. Proc. Natl. Acad. Sci. USA 78:4204-4208.
5. Brosius, J. 1984. Plasmid vectors for the selection of promoters. Gene 27:151-160.
6. Brosius, J. 1989. Superlinkers in cloning and expression vectors. DNA 8:759-777.
7. Cheo, D. L., K. W. Bayles, and R. E. Yasbin. 1991. Cloning and characterization of DNA damage-inducible promoter regions from Bacillus subtilis. J. Bacteriol. 173:1696-1703.
8. Cheo, D. L., K. W. Bayles, and R. E. Yasbin. 1993. Elucidation of regulatory elements that control damage induction and competence induction of the Bacillus subtilis SOS system. J. Bacteriol. 175:5907-5915.
9. Clark-Curtiss, J. E., W. R. Jacobs, M. A. Docherty, L. R. Ritchie, and R. Curtiss. 1985. Molecular analysis of DNA and construction of genomic libraries of Mycobacterium leprae. J. Bacteriol. 161:1093-1102.
10. Colston, M. J., and E. O. Davis. 1994. The ins and outs of protein splicing elements. Mol. Microbiol. 12:359-363.
11. Das Gupta, S. K., M. D. Bashyam, and A. K. Tyagi. 1993. Cloning and assessment of mycobacterial promoters by using a plasmid shuttle vector. J. Bacteriol. 175:5186-5192.
12. Davis, E. O., S. G. Sedgwick, and M. J. Colston. 1991. Novel structure of the recA locus of Mycobacterium tuberculosis implies processing of the gene product. J. Bacteriol. 173:5653-5662.
13. Davis, E. O., P. J. Jenner, P. C. Brooks, M. J. Colston, and S. G. Sedgwick. 1992. Protein splicing in the maturation of M. tuberculosis recA protein: a mechanism for tolerating a novel class of intervening sequence. Cell 71:201-210.
14. Davis, E. O., H. S. Thangaraj, P. C. Brooks, and M. J. Colston. 1994. Evidence of selection for protein introns in the RecAs of pathogenic mycobacteria. EMBO J. 13:699-703.
15. Doukhan, L., M. Predich, G. Nair, O. Dussurget, I. Mandic-Mulec, S. T. Cole, D. R. Smith, and I. Smith. 1995. Genomic organization of the mycobacterial sigma gene cluster. Gene 165:67-70.
16. Favre, D., and J.-F. Viret. 1990. Nucleotide sequence of the recA gene of Bordetella pertussis. Nucleic Acids Res. 18:4243.
17. Fernandez de Henestrosa, A. R., S. Calero, and J. Barbe. 1991. Expression of the recA gene of Escherichia coli in several species of gram-negative bacteria. Mol. Gen. Genet. 226:503-506.
18. Gassel, M., and J. C. Alonso. 1989. Expression of the recE gene during induction of the SOS response in Bacillus subtilis recombination-deficient strains. Mol. Microbiol. 3:1269-1276.
19. Gonzalez-y-Merchand, J. A., M. J. Colston, and R. A. Cox. 1996. The rRNA operons of Mycobacterium smegmatis and Mycobacterium tuberculosis: comparison of promoter elements and of neighbouring upstream genes. Microbiology (Reading) 142:667-674.
20. Haijema, B. J., D. van Sinderen, K. Winterling, J. Kooistra, G. Venema, and L. W. Hamoen. 1996. Regulated expression of the dinR and recA genes during competence development and SOS induction in Bacillus subtilis. Mol. Microbiol. 22:75-85.
21. Haseltine, W. A. 1983. Ultraviolet light repair and mutagenesis revisited. Cell 33:13-17.
22. Holmes, D. S., and M. Quigley. 1981. A rapid boiling method for the preparation of bacterial plasmids. Anal. Biochem. 114:193-197.
23. Iyer, V. N., and W. Szybalski. 1963. A molecular mechanism of mitomycin action: linking of complementary DNA strands. Proc. Natl. Acad. Sci. USA 50:355-365.
24. Iyer, V. N., and W. Szybalski. 1964. Mitomycins and porfiromycin: chemical mechanism of activation and cross-linking of DNA. Science 145:55-68.
25. Jackson, M., F.-X. Baerthet, I. Otal, J. Rauzier, C. Martin, B. Gicquel, and C. Guilhot. 1996. The Mycobacterium tuberculosis purine biosynthetic pathway: isolation and characterisation of the purC and purL genes. Microbiology (Reading) 142:2439-2447.
26. Kenney, T. J., and G. Churchward. 1996. Genetic analysis of the Mycobacterium smegmatis rpsL promoter. J. Bacteriol. 178:3564-3571.
27. Lewis, L. K., M. E. Jenkins, and D. W. Mount. 1992. Isolation of DNA damage-inducible promoters in Escherichia coli: regulation of polB (dinA), dinG, and dinH by LexA repressor. J. Bacteriol. 174:3377-3385.
28. Lin, K. C., and D. Shiuan. 1995. A simple method for DNaseI footprinting analysis. J. Biochem. Biophys. Methods 30:85-89.
29. Little, J. W. 1984. Autodigestion of LexA and phage lambda repressors. Proc. Natl. Acad. Sci. USA 81:1375-1379.
30. Little, J. W. 1991. Mechanism of specific LexA cleavage: autodigestion and the role of RecA coprolease. Biochimie 73:411-422.
31. Little, J. W., and D. W. Mount. 1982. The SOS regulatory system of Escherichia coli. Cell 29:11-22.
32. Little, J. W., D. W. Mount, and C. R. Yanisch-Perron. 1981. Purified LexA protein is a repressor of the recA and lex.4 genes. Proc. Natl. Acad. Sci. USA 78:4199-4203.
33. Liu, Y., A. Chatterjee, and A. K. Chatterjee. 1994. Nucleotide sequence, organization and expression of rdgA and rdgB genes that regulate pectin lyase production in the plant pathogenic bacterium Erwinia carotovora subsp. carotovora in response to DNA-damaging agents. Mol. Microbiol. 14:999-1010.
34. Lovett, C. M., Jr., K. C. Cho, and T. M. O'Gara. 1993. Purification of an SOS repressor from Bacillus subtilis. J. Bacteriol. 175:6842-6849.
35. Matsui, H., Y. Sano, H. Ishihara, and T. Shinomiya. 1993. Regulation of pyocin genes in Pseudomonas aeruginosa by positive (prtN) and negative (prtR) regulatory genes. J. Bacteriol. 175:1257-1263.
36. McEvoy, J. L., H. Murata, and A. K. Chatterjee. 1992. Genetic evidence for an activator required for induction of pectin lyase in Erwinia carotovora subsp. carotovora by DNA-damaging agents. J. Bacteriol. 174:5471-5474.
37. Miller, R. V., and T. A. Kokjohn. 1990. General microbiology of recA: environmental and evolutionary significance. Annu. Rev. Microbiol. 44:365-394.
38. Movahedzadeh, F., M. J. Colston, and E. O. Davis. 1997. Characterisation of Mycobacterium tuberculosis LexA: recognition of a Cheo (Bacillus-type SOS) box. Microbiology (Reading) 143:929-936.
39. Nakazawa, T., M. Kimoto, and M. Abe. 1990. Cloning, sequencing, and transcriptional analysis of the recA gene of Pseudomonas cepacia. Gene 94:83-88.
40. Perler, F. B., E. O. Davis, G. E. Dean, F. S. Gimble, W. E. Jack, N. Neff, C. J. Noren, J. Thorner, and M. Belfort. 1994. Protein splicing elements: inteins and exteins - a definition of terms and recommended nomenclature. Nucleic Acids Res. 22:1125-1127.
41. Pogson, C. A., C. P. Simmons, R. A. Strugnell, and A. L. M. Hodgson. 1996. Cloning and manipulation of the Corynebacterium pseudotuberculosis recA gene for live vaccine vector development. FEMS Microbiol. Lett. 142:139-145.
42. Predich, M., L. Doukhan, G. Nair, and I. Smith. 1995. Characterization of RNA polymerase and two sigma-factor genes from Mycobacterium smegmatis. Mol. Microbiol. 15:355-366.
43. Ranes, M. G., J. Rauzier, M. Lagranderie, M. Gheorghiu, and B. Gicquel. 1990. Functional analysis of pAL5000, a plasmid from Mycobacterium fortuitum: construction of a "mini" mycobacterium-Escherichia coli shuttle vector. J. Bacteriol. 172:2793-2797.
44. Raymond-Denise, A., and N. Guillen. 1992. Expression of the Bacillus subtilis dinR and recA genes after DNA damage and during competence. J. Bacteriol. 174:3171-3176.
45. Revel-Viravau, V., Q. C. Truong, N. Moreau, V. Jarlier, and W. Sougakoff. 1996. Sequence analysis, purification, and study of inhibition by 4-quinolones of the DNA gyrase from Mycobacterium smegmatis. Antimicrob. Agents Chemother. 40:2054-2061.
46. Rosenberg, M., and D. Court. 1979. Regulatory sequences involved in the promotion and termination of RNA transcription. Annu. Rev. Genet. 13: 319-353.
47. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
48. Schnarr, M., P. Oertel-Buchheit, M. Kazmaier, and M. Granger-Schnarr. 1991. DNA binding properties of the LexA repressor. Biochimie 73:423-431.
49. Snapper, S. B., L. Lugosi, A. Jekkel, R. E. Melton, T. Kieser, B. R. Bloom, and W. R. Jacobs. 1988. Lysogeny and transformation in mycobacteria: stable expression of foreign genes. Proc. Natl. Acad. Sci. USA 85:6987-6991.
50. Stolt, P., and N. G. Stoker. 1996. Functional definition of regions necessary for replication and incompatibility in the Mycobacterium fortuitum plasmid pAL5000. Microbiology (Reading) 142:2795-2802.
51. Stover, C. K., V. F. de-la-Cruz, T. R. Fuerst, J. E. Burlein, L. A. Benson, L. T. Bennett, G. P. Bansal, J. F. Young, M. H. Lee, G. F. Hatfull, S. B. Snapper, R. G. Barletta, W. R. Jacobs, and B. R. Bloom. 1991. New use of BCG for recombinant vaccines. Nature 351:456-460.
52. Strohl, W. R. 1992. Compilation and analysis of DNA sequences associated with apparent streptomycete promoters. Nucleic Acids Res. 20:961-974.
53. Sugino, A., C. L. Peebles, K. N. Kreuzer, and N. R. Cozzarelli. 1977 Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. Proc. Natl. Acad. Sci. USA 74:4767-4771.
54. Takiff, H. E., M. Cimino, M. C. Musso, T. Weisbrod, R. Martinez, M. B. Delgado, L. Salazar, B. R. Bloom, and W. R. Jacobs, Jr. 1996. Efflux pump of the proton antiporter family confers low-level fluoroquinolone resistance in Mycobacterium smegmatis. Proc. Natl. Acad. Sci. USA 93:362-366.
55. van den Berg, E. A., R. H. Geerse, H. Pannekoek, and P. van de Putte. 1983. In vivo transcription of the E. coli uvrB gene: both promoters are inducible by UV. Nucleic Acids Res. 11:4355-4363.
56. Walker, G. C. 1984. Mutagenesis and inducible responses to deoxyribonueleic acid damage in Escherichia coli. Microbiol. Rev. 48:60-93.
57. Weisemann, J. M., and G. M. Weinstock. 1991. The promoter of the recA gene of Eschirichia coli. Biochimie 73:457-470.
58. Weisemann, J. M., C. Funk, and G. M. Weinstock. 1984. Measurement of in vivo expression of the recA gene of Escherichia coli by using lacZ gene fusions. J. Bacteriol. 160:112-121.
59. Yanisch-Perron, C., J. Vieira, and J. Messing. 1985. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33:103-119.
60. Zhao, X. J., and K. McEntee. 1990. DNA sequence analysis of the recA genes from Proteus vulgaris, Erwinia crotovora, Shigella flexneri and Escherichia coli B/r. Mol. Gen. Genet. 222:369-376.