Further evidence for a dopamine reuptake pharmacophore. The effect of N-methylation on threo-methylphenidate and its analogs

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 9, 1997, Pages 1213-1218

  Froimowitz, Mark ^a   Deutsch, Howard M ^b   Shi, Quing ^b   Wu, Kuo Ming ^a   Glaser, Robert ^c   Adin, Itay ^c   George, Clifford ^d   Schweri, Margaret M ^e  

^a Pharm Eco Laboratories Inc   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^d NAVAL RESEARCH LABORATORY   (United States)

^e MERCER UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; DOPAMINE TRANSPORTER; METHYLPHENIDATE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CALCULATION; CONTROLLED STUDY; CORPUS STRIATUM; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; IN VITRO STUDY; METHYLATION; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; STRUCTURE ACTIVITY RELATION; THEORY; X RAY CRYSTALLOGRAPHY;

EID: 0030952522     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00193-5     Document Type: Article

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