Effects of an inhibitor of cathepsin L on bone resorption in thyroparathyroidectomized and ovariectomized rats

Bone

Volumn 20, Issue 5, 1997, Pages 465-471

  Millest, A J ^a   Breen, S A ^a   Loveday, B E ^a   Clarkson, P N ^a   Simpson, C A ^a   Waterton, J C ^a   Johnstone, D ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Bone; Cathepsin, proteinase, thyroparathyroidectomized, ovariectomized; Computed tomography; Rat

Indexed keywords

4 [2 (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 NAPHTHYL) 1 PROPENYL]BENZOIC ACID ETHYL ESTER; ACETYLLEUCYLLEUCYLNORLEUCINOL; ALENDRONIC ACID; AROTINOID; CATHEPSIN L; COLLAGEN; CYSTEINE PROTEINASE; INCADRONIC ACID; PROTEINASE INHIBITOR; SALCATONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE ATROPHY; BONE DENSITY; BONE MINERAL; COLLAGEN DEGRADATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORTICAL BONE; DRUG EFFICACY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FEMALE; HYPERCALCEMIA; INTRAPERITONEAL DRUG ADMINISTRATION; LONGITUDINAL STUDY; MALE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; OVARIECTOMY; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; THYROPARATHYROIDECTOMY;

ANIMALS; BENZOATES; BONE RESORPTION; CATHEPSINS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DISEASE MODELS, ANIMAL; ENDOPEPTIDASES; FEMALE; HUMANS; HYPERCALCEMIA; LEUPEPTINS; MALE; OSTEOPOROSIS; OVARIECTOMY; OVARY; PARATHYROID GLANDS; PARATHYROIDECTOMY; RATS; RATS, WISTAR; RETINOIDS; THYROID GLAND; THYROIDECTOMY;

EID: 0030949702     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(97)00014-8     Document Type: Article

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