메뉴 건너뛰기




Volumn 38, Issue 3, 1997, Pages 205-211

Kainate-induced DNA damage and p53 immunoreactivity in the rat hippocampus: Protection with melatonin

Author keywords

Apoptosis; Hippocampus; Kainic acid; Melatonin

Indexed keywords

CELL DNA; EXCITOTOXIN; GLUTAMATE RECEPTOR AGONIST; KAINIC ACID; MELATONIN; PINEAL BODY HORMONE; PROTEIN P53;

EID: 0030930748     PISSN: 03539504     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (6)

References (37)
  • 1
    • 0028955117 scopus 로고
    • Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity
    • Giusti P, Gusella M, Lipartiti M, Milani D, Zhu W, Vicini S, et al. Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity. Exp Neurol 1995;131:39-46.
    • (1995) Exp Neurol , vol.131 , pp. 39-46
    • Giusti, P.1    Gusella, M.2    Lipartiti, M.3    Milani, D.4    Zhu, W.5    Vicini, S.6
  • 2
    • 0030218902 scopus 로고    scopus 로고
    • Protective effect of melatonin against hippocampal DNA damage induced by intraperitoneal administration of kainate to rats
    • Uz T, Giusti P, Franceschini D, Kharlamov A, Manev H. Protective effect of melatonin against hippocampal DNA damage induced by intraperitoneal administration of kainate to rats. Neuroscience 1996;73:631-6.
    • (1996) Neuroscience , vol.73 , pp. 631-636
    • Uz, T.1    Giusti, P.2    Franceschini, D.3    Kharlamov, A.4    Manev, H.5
  • 4
    • 0030136147 scopus 로고    scopus 로고
    • In vitro and in vivo protection against kainate-induced excitotoxicity by melatonin
    • Giusti P, Franceschini D, Petrone M, Manev H, Floreani M. In vitro and in vivo protection against kainate-induced excitotoxicity by melatonin. J Pineal Res 1996;20:226-31.
    • (1996) J Pineal Res , vol.20 , pp. 226-231
    • Giusti, P.1    Franceschini, D.2    Petrone, M.3    Manev, H.4    Floreani, M.5
  • 5
    • 0029082155 scopus 로고
    • Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions
    • Melchiorri D, Reiter RJ, Sewerynek E, Chen LD, Nistico G. Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions. FASEB J 1995;9:1205-10.
    • (1995) FASEB J , vol.9 , pp. 1205-1210
    • Melchiorri, D.1    Reiter, R.J.2    Sewerynek, E.3    Chen, L.D.4    Nistico, G.5
  • 6
    • 0027968017 scopus 로고
    • Pineal function during aging: Attenuation of the melatonin rhythm and its neurobiological consequences
    • Reiter RJ. Pineal function during aging: attenuation of the melatonin rhythm and its neurobiological consequences. Acta Neurobiol Exp 1994;54 Suppl:31-9.
    • (1994) Acta Neurobiol Exp , vol.54 , Issue.SUPPL. , pp. 31-39
    • Reiter, R.J.1
  • 7
    • 0014887088 scopus 로고
    • Actions of several antihelminthics and insecticides on rat cortical neurons
    • Shinozaki H, Konishi S. Actions of several antihelminthics and insecticides on rat cortical neurons. Brain Res 1970;24:368-71.
    • (1970) Brain Res , vol.24 , pp. 368-371
    • Shinozaki, H.1    Konishi, S.2
  • 8
    • 0016230519 scopus 로고
    • Kainic acid: A powerful neurotoxic analogue of glutamate
    • Olney JVV, Rhee V, Ho OL. Kainic acid: a powerful neurotoxic analogue of glutamate. Brain Res 1974;77:507-512.
    • (1974) Brain Res , vol.77 , pp. 507-512
    • Olney, J.V.V.1    Rhee, V.2    Ho, O.L.3
  • 9
    • 0018100593 scopus 로고
    • In situ injection of kainic acid: A new method for selectively lesioning neuronal cell bodies while sparing axons of passage
    • Coyle JT, Molliver MR, Kuhar MJ. In situ injection of kainic acid: a new method for selectively lesioning neuronal cell bodies while sparing axons of passage. J Comp Neurol 1978;180:301-18.
    • (1978) J Comp Neurol , vol.180 , pp. 301-318
    • Coyle, J.T.1    Molliver, M.R.2    Kuhar, M.J.3
  • 10
    • 0019472821 scopus 로고
    • Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline and pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy
    • Ben-Ari Y, Tremblay E, Richie D, Ghilini G, Naquet R. Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline and pentetrazole: metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy. Neuroscience 1981;6:1361-91.
    • (1981) Neuroscience , vol.6 , pp. 1361-1391
    • Ben-Ari, Y.1    Tremblay, E.2    Richie, D.3    Ghilini, G.4    Naquet, R.5
  • 11
    • 0019501929 scopus 로고
    • Kainic acid-induced limbic motor seizures: Metabolic, behavioral, electroencephalographic and neuropathological correlates
    • Lothman EW, Collins RC. Kainic acid-induced limbic motor seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates. Brain Res 1981;218:299-318.
    • (1981) Brain Res , vol.218 , pp. 299-318
    • Lothman, E.W.1    Collins, R.C.2
  • 12
    • 0028917654 scopus 로고
    • Oxygen free radicals in rat limbic structures after kainate-induced seizures
    • Bruce AJ, Baudry M. Oxygen free radicals in rat limbic structures after kainate-induced seizures. Free Radic Biol Med 1995;18:993-1002.
    • (1995) Free Radic Biol Med , vol.18 , pp. 993-1002
    • Bruce, A.J.1    Baudry, M.2
  • 13
    • 0027251608 scopus 로고
    • Oxidative stress induced by glutamate receptor agonists
    • Bondy SC, Lee DK. Oxidative stress induced by glutamate receptor agonists. Brain Res 1993;610:229-33.
    • (1993) Brain Res , vol.610 , pp. 229-233
    • Bondy, S.C.1    Lee, D.K.2
  • 14
    • 0028118703 scopus 로고
    • Trolox attenuates cortical neuronal injury induced by iron, ultraviolet light, glucose deprivation, or AMPA
    • Chow HS, Lynch JJ, Rose K, Choi DW. Trolox attenuates cortical neuronal injury induced by iron, ultraviolet light, glucose deprivation, or AMPA. Brain Res 1994;639:102-8.
    • (1994) Brain Res , vol.639 , pp. 102-108
    • Chow, H.S.1    Lynch, J.J.2    Rose, K.3    Choi, D.W.4
  • 16
    • 0028087976 scopus 로고
    • p53 induction is associated with neuronal damage in the central nervous system
    • Sakhi S, Bruce A, Sun N, Tocco G, Baudry M. p53 induction is associated with neuronal damage in the central nervous system. Proc Natl Acad Sci USA 1994;91:7525-9.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7525-7529
    • Sakhi, S.1    Bruce, A.2    Sun, N.3    Tocco, G.4    Baudry, M.5
  • 17
    • 0027931560 scopus 로고
    • DNA fragmentation in rat brain after intraperitoneal administration of kainate
    • Filipowski RK, Hetman M, Kaminska B, Kaczmarek L. DNA fragmentation in rat brain after intraperitoneal administration of kainate. Neuroreport 1994;5:1538-40.
    • (1994) Neuroreport , vol.5 , pp. 1538-1540
    • Filipowski, R.K.1    Hetman, M.2    Kaminska, B.3    Kaczmarek, L.4
  • 18
    • 0029077393 scopus 로고
    • NMDA and kainate induce internucleosomal DNA cleavage associated with both apoptotic and necrotic cell death in the neonatal rat brain
    • Van Lookeren Campagne M, Lucassen PJ, Vermeulen JP, Balázs R. NMDA and kainate induce internucleosomal DNA cleavage associated with both apoptotic and necrotic cell death in the neonatal rat brain. Eur J Neurosci 1995;7:1627-40.
    • (1995) Eur J Neurosci , vol.7 , pp. 1627-1640
    • Van Lookeren Campagne, M.1    Lucassen, P.J.2    Vermeulen, J.P.3    Balázs, R.4
  • 19
    • 0029867466 scopus 로고    scopus 로고
    • Nuclear accumulation of p53 protein following kainic acid-induced seizures
    • Sakhi S, Sun N, Wing LL, Mehta P, Schreiber SS. Nuclear accumulation of p53 protein following kainic acid-induced seizures. Neuroreport 1996;7:493-6.
    • (1996) Neuroreport , vol.7 , pp. 493-496
    • Sakhi, S.1    Sun, N.2    Wing, L.L.3    Mehta, P.4    Schreiber, S.S.5
  • 20
    • 0028057773 scopus 로고
    • Kainic acid seizures in the rat
    • Sperk G. Kainic acid seizures in the rat. Prog Neurobiol 1994;42:1-32.
    • (1994) Prog Neurobiol , vol.42 , pp. 1-32
    • Sperk, G.1
  • 22
    • 0028567078 scopus 로고
    • Photochemical brain injury in rats triggers DNA fragmentation, p53, and HSP72
    • Manev H, Kharlamov A, Amstrong DM. Photochemical brain injury in rats triggers DNA fragmentation, p53, and HSP72. Neuroreport 1994;5:2661-4.
    • (1994) Neuroreport , vol.5 , pp. 2661-2664
    • Manev, H.1    Kharlamov, A.2    Amstrong, D.M.3
  • 23
    • 0029897378 scopus 로고    scopus 로고
    • In vivo protection against kainate-induced apoptosis by the pineal hormone melatonin: Effect of exogenous melatonin and circadian rhythm
    • Manev H, Uz T, Kharlamov A, Cagnoli CM, Franceschini D, Giusti P. In vivo protection against kainate-induced apoptosis by the pineal hormone melatonin: effect of exogenous melatonin and circadian rhythm. Restorative Neurology and Neuroscience 1996;9:251-6.
    • (1996) Restorative Neurology and Neuroscience , vol.9 , pp. 251-256
    • Manev, H.1    Uz, T.2    Kharlamov, A.3    Cagnoli, C.M.4    Franceschini, D.5    Giusti, P.6
  • 24
    • 0029088484 scopus 로고
    • Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator
    • Tsirka SE, Gualandris A, Amaral DG, Strickland S. Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature 1995;377:340-4.
    • (1995) Nature , vol.377 , pp. 340-344
    • Tsirka, S.E.1    Gualandris, A.2    Amaral, D.G.3    Strickland, S.4
  • 25
    • 0017755164 scopus 로고
    • Epileptogenic action of intraventricularly injected melatonin antibody
    • Fariello RG, Bubenik GA, Brown GM, Grota LJ. Epileptogenic action of intraventricularly injected melatonin antibody. Neurology 1977; 27:567-70.
    • (1977) Neurology , vol.27 , pp. 567-570
    • Fariello, R.G.1    Bubenik, G.A.2    Brown, G.M.3    Grota, L.J.4
  • 26
    • 0014343501 scopus 로고
    • EEG and convulsive threshold changes produced by pineal extract administra-tion
    • Rolánd E, Antón-Tay F. EEG and convulsive threshold changes produced by pineal extract administra-tion. Brain Res 1968;11:238-45.
    • (1968) Brain Res , vol.11 , pp. 238-245
    • Rolánd, E.1    Antón-Tay, F.2
  • 27
    • 0015376906 scopus 로고
    • Attempts to characterize the convulsive response of parathyroidectomized rats to pineal gland removal
    • Reiter RJ, Morgan WW. Attempts to characterize the convulsive response of parathyroidectomized rats to pineal gland removal. Physiol Behav 1972;9:203-8.
    • (1972) Physiol Behav , vol.9 , pp. 203-208
    • Reiter, R.J.1    Morgan, W.W.2
  • 28
    • 10544255343 scopus 로고    scopus 로고
    • Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats
    • Manev H, Uz T, Kharlamov A, Jin J-Y. Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats. FASEB J 1996;10:1546-51.
    • (1996) FASEB J , vol.10 , pp. 1546-1551
    • Manev, H.1    Uz, T.2    Kharlamov, A.3    Jin, J.-Y.4
  • 29
    • 0030272509 scopus 로고    scopus 로고
    • Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation
    • Hughes PE, Alexi T, Yoshida T, Schreiber SS, Knusel B. Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation. Neuroscience 1996;74:1143-60.
    • (1996) Neuroscience , vol.74 , pp. 1143-1160
    • Hughes, P.E.1    Alexi, T.2    Yoshida, T.3    Schreiber, S.S.4    Knusel, B.5
  • 30
    • 0029127992 scopus 로고
    • Selective neuronal vulnerability in the hippocampus - A role for gene expression?
    • Schreiber SS, Baudry M. Selective neuronal vulnerability in the hippocampus - a role for gene expression? Trends in Neurosciences 1995;18:446-51.
    • (1995) Trends in Neurosciences , vol.18 , pp. 446-451
    • Schreiber, S.S.1    Baudry, M.2
  • 31
    • 0029001403 scopus 로고
    • Upregulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain
    • Gillardon F, Wickert H, Zimmermann M. Upregulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain. Neurosci Lett 1995;192:85-8.
    • (1995) Neurosci Lett , vol.192 , pp. 85-88
    • Gillardon, F.1    Wickert, H.2    Zimmermann, M.3
  • 33
    • 0028075436 scopus 로고
    • Dynamic changes in the composition of the AP-1 transcription factor DNA-binding activity in rat brain following kainate-induced seizures and cell death
    • Kaminska B, Filipkowski RK, Zurkowska G, Lason W, Przewlocki R, Kaczmarek L. Dynamic changes in the composition of the AP-1 transcription factor DNA-binding activity in rat brain following kainate-induced seizures and cell death. Eur J Neurosci 1994;6:1558-66.
    • (1994) Eur J Neurosci , vol.6 , pp. 1558-1566
    • Kaminska, B.1    Filipkowski, R.K.2    Zurkowska, G.3    Lason, W.4    Przewlocki, R.5    Kaczmarek, L.6
  • 35
    • 0029295723 scopus 로고
    • Melatonin protects neurons from singlet oxygen-induced apoptosis
    • Cagnoli CM, Atabay C, Kharlamov E, Manev H. Melatonin protects neurons from singlet oxygen-induced apoptosis. J Pineal Res 1995;18:222-6.
    • (1995) J Pineal Res , vol.18 , pp. 222-226
    • Cagnoli, C.M.1    Atabay, C.2    Kharlamov, E.3    Manev, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.