Synthesis, evaluation and Tc-99m complexation of a hydrazinonicotinyl conjugate of a GP IIb/IIIa antagonist cyclic peptide for the detection of deep vein thrombosis

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 8, 1997, Pages 955-960

  Rajopadhye, Milind ^a   Harris, Thomas D ^a   Yu, Karmine ^a   Glowacka, Danuta ^a   Damphousse, Paul R ^a   Barrett, John A ^a   Heminway, Stuart J ^a   Edwards, D Scott ^a   Carroll, Timothy R ^a  

^a Du Pont Merck Pharmaceutical Company   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPEPTIDE; DMP 757; FIBRINOGEN RECEPTOR ANTAGONIST; RP 444; TECHNETIUM 99M; TECHNETIUM COMPLEX; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DOG; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; THROMBOCYTE; THROMBUS;

EID: 0030901407     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00083-8     Document Type: Article

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25. 50 values were calculated by fitting the percent inhibition values to a regression line.