Thrombus imaging using technetium-99m-labeled high-potency GPIIb/IIIa receptor antagonists. Chemistry and initial biological studies

Journal of Medicinal Chemistry

Volumn 39, Issue 7, 1996, Pages 1372-1382

  Pearson, Daniel A ^a   Lister James, John ^a   McBride, William J ^a   Wilson, David M ^a   Martel, Lawrence J ^a   Civitello, Edgar R ^a   Dean, Richard T ^a  

^a Chemistry Department   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHELATING AGENT; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ANTAGONIST; P 280; P 748; RADIOISOTOPE; SYNTHETIC PEPTIDE; TECHNETIUM 99M; TECHNETIUM COMPLEX; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; BINDING AFFINITY; DEEP VEIN THROMBOSIS; DIAGNOSTIC IMAGING; DOG; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; NONHUMAN; NUCLEAR MEDICINE; PEPTIDE SYNTHESIS; RADIOISOTOPE DIAGNOSIS; RECEPTOR BINDING; THROMBOEMBOLISM; THROMBOSIS;

AMINO ACID SEQUENCE; ANIMALS; CHELATING AGENTS; DOGS; FEMORAL VEIN; HUMANS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OLIGOPEPTIDES; ORGANOTECHNETIUM COMPOUNDS; PEPTIDES, CYCLIC; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; TECHNETIUM COMPOUNDS; THROMBOSIS;

EID: 0029925434     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950112e     Document Type: Article

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