Biological evaluation of99mTc-labeled cyclic glycoprotein IIb/IIIa receptor antagonists in the canine arteriovenous shunt and deep vein thrombosis models: Effects of chelators on biological properties of [99mTc]chelator-peptide conjugates

Bioconjugate Chemistry

Volumn 7, Issue 2, 1996, Pages 203-208

  Barrett, John A ^a   Damphousse, David J ^a   Heminway, Stuart J ^a   Liu, Shuang ^a   Scott Edwards, D ^a   Looby, Richard J ^a   Carroll, Timothy R ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHELATION; DISEASES; GLYCOPROTEINS; PEPTIDES; PLATELETS;

ARTERIOVENOUS SHUNT; BIOLOGICAL EVALUATION; BIOLOGICAL PROPERTIES; CONDITION; DEEP VEIN THROMBOSIS; GLYCOPROTEIN IIB/IIIA RECEPTOR; IMAGING AGENT; MODELING EFFECTS; POST INJECTION; RECEPTOR ANTAGONISTS;

BLOOD VESSELS;

CHELATING AGENT; CYCLIC (ARGINYL GLYCYL ASPARTYL PHENYLALANYL LYSYL); CYCLIC (ARGINYL-GLYCYL-ASPARTYL-PHENYLALANYL-LYSYL); CYCLOPEPTIDE; DIAGNOSTIC AGENT; FIBRINOGEN; FIBRINOGEN RECEPTOR; PERTECHNETIC ACID TC 99M; SERUM ALBUMIN;

ANIMAL; ARTERIOVENOUS SHUNT; ARTICLE; CHEMICAL STRUCTURE; DOG; DRUG ANTAGONISM; FEMALE; ISOTOPE LABELING; MALE; METABOLISM; SCINTISCANNING; THROMBOCYTE; THROMBOPHLEBITIS; THROMBOSIS;

ANIMALS; ARTERIOVENOUS SHUNT, SURGICAL; BLOOD PLATELETS; CHELATING AGENTS; DOGS; FEMALE; FIBRINOGEN; ISOTOPE LABELING; MALE; MOLECULAR STRUCTURE; PEPTIDES, CYCLIC; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; SERUM ALBUMIN; SODIUM PERTECHNETATE TC 99M; THROMBOPHLEBITIS; THROMBOSIS;

EID: 0030091203     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc9500960     Document Type: Article

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