Inter- and intraclade neutralization of human immunodeficiency virus type 1: Genetic clades do not correspond to neutralization serotypes but partially correspond to gp120 antigenic serotypes

Journal of Virology

Volumn 70, Issue 1, 1996, Pages 427-444

  Moore, John P ^a   Cao, Yunzhen ^a   Leu, John ^a   Qin, Limo ^a   Korber, Bette ^b   David, D H O ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ARTICLE; GENETIC VARIABILITY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; SEROTYPE; VIRUS ISOLATION; VIRUS NEUTRALIZATION;

AMINO ACID SEQUENCE; ANTIBODIES, VIRAL; HIV ENVELOPE PROTEIN GP120; HIV SEROPOSITIVITY; HIV-1; HUMAN; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; SEROTYPING; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; VARIATION (GENETICS);

EID: 0029656045     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.1.427-444.1996     Document Type: Article

References (61)

1. Abimiku, A. G., T. L. Stern, A. Zwander, P. D. Markham, C. Calef, S. Kyari, W. C. Saxinger, R. C. Gallo, M. Robert-Guroff, and M. S. Reitz. 1994. Subgroup G HIV type 1 isolates from Nigeria AIDS Res. Hum. Retroviruses 10:1581-1583.
2. Anzala, O. A., N. J. D. Nagelkerke, J. J. Bwayo, D. Holton, S. Moses, E. N. Ngugi, J. O. Ndinya-Achola, and F. A. Plummer. 1995. Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection J. Infect. Dis. 171:686-689.
3. Baehman, M. H., E. L. Delwart, E. G. Shpaer, P. Lingenfelter, R. Singal, J. I. Mullins, and the WHO Network for HIV Isolation and Characterisation. 1994. Rapid genetic characterization of HIV type 1 strains from four World Health Organization-sponsored vaccine evaluation sites using a heterodupiex mobility assay. AIDS Res. Hum. Retroviruses 10:1345-1354.
4. Bobkov, A., R. Cheingsong-Popov, M. Garaev, A. Rzhaninova, P. Kaleebu, S. Beddows, M. H. Bachmann, J. I. Mullins, J. Louwagie, W. Janssens, G. van der Groen, F. McCutchan, and J. Weber. 1994. Identification of an env G subtype and heterogeneity of HIV-1 strains in the Russian Federation and Belarus. AIDS 8:1649-1655.
5. Cao, Y., L. Qin, L. Zhang, J. Safrit, and D. D. Ho. 1995. Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection. N. Engl. J. Med. 332:201-208.
6. Cheingsong-Popov, R., S. Lister, D. Callow, P. Kaleehu, S. Beddows, J. N. Weber, and the WHO Network for HIV Isolation and Characterisation. 1994. Serotyping HIV-1 through antibody binding to the V3 loop: relationship to viral genotype. AIDS Res Hum. Retroviruses 10:1379-1386
7. Cheng-Mayer, C., J. Homsy, L. A. Evans, and J. A. Levy. 1988 Identification of human immunodeficiency virus subtypes with distinct patterns of sensitivity to serum neutralization. Proc Natl. Acad Sci. USA 85:2815-2819.
8. Cohen, J. 1993. Jitters jeopardize AIDS vaccine trials Science 262:980-981.
9. Daar, E. S., X. L. Li, T. Moudgit, and D. D. Ho. 1990. High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates. Proc. Natl. Acad, Sci. USA 87:6574-6578.
10. Delwart, E. L., E. G. Shpaer, J. Louwagie, F. E. McCutchan, M. Grez, H. Rübsamen-Waigman, and J. I. Mullins. 1993 Genetic relationships determined by a DNA heteroduplex mobility assay: analysis of HIV-1 env genes. Science 262:1257-1261.
11. de Wolf, F., E. Hugervorst, J. Goudsmit, E.-M. Fenyö, H. Rubsamen-Waigmann, H. Holmes, B. Galvao-Castro, E. Karita, C. Wasi, S. D. K. Sempala, E. Baan, F. Zorgdrager, V. Lukashov, S. Osmanov, C. Kuiken, M. Cornelissen, and the WHO Network for HIV Isolation and Characterisation. 1994. Syncytium inducing (SI) and non-syncytium-induemg (NSI) capacity of human immunodeficiency virus type 1 (HIV-1) subtypes other than B: phenotypic and genotypic characteristics AIDS Res. Hum Retroviruses 10:1387-1400.
12. Dumitrescu, O., M. L. Kalish, S. C. Kliks, C. I. Bandea, and J. A. Levy. 1994 Characterization of human immunodeficiency virus type 1 isolates from children in Romania' identification of a new envelope subtype. J. Infect Dis. 169:281-288.
13. Gao, F., L. Yue, S. Craig, C. L. Thornton, D. L. Robertson, F. E. McCutchan, J. A. Bradac, P. M. Sharp, B. H. Hahn, and the WHO Network for HIV Isolation and Characterisation. 1994. Genetic variation of HIV-1 in four WHO-sponsored vaccine evaluation sites: generation of functional envelope (gp160) clones representative of sequence subtypes A. B. C, and E. AIDS Res. Hum. Retroviruses 10:1359-1368.
14. Gürtler, L. G., P. H. Hauser, J. Eberle, A. von Braun, S. Knapp, L. Zekeng, J. M. Tsague, and L. Kaptue. 1994. A new subtype of human immunodefi ciency virus type I (MVP-5180) from Cameroon. J Virol 68:1581-1585.
15. Hahn, B. H. Personal communication.
16. Hanson, C. V. 1994. Measuring vaccine-induced HIV neutralization, report of a workshop. AIDS Res. Hum. Retroviruses 10:645-648.
17. Ichimura, H., S. C. Kliks, S. Visrutaratna, C.-Y. Ou, M. L. Kalish, and J. A. Levy. 1994 Biological, scrological. and genetic characterization of HIV-1 subtype E isolates from Thailand. AIDS Res. Hum. Retroviruses 10:263-269.
18. Kalish, M. L., C.-C. Luo, B. G. Weniger, K. Limpakarnjanarat, N. Young, C.-Y. Ou, and G. Schochetman. 1994. Early HIV type 1 strains in Thailand were not responsible for the current epidemic. AIDS Res. Hum. Retroviluses 10:1573-1576
19. Korber, B. T. M., E. E. Allen, A. D. Farmer, and G. L. Myers. 1995. Heterogeneity of HIV-1 and HIV-2. AIDS 9:S5-S18
20. Korber, B. T. M., K. MacInnes, R. Smith, and G. L. Myers. 1994. Mutational trends in V3 loop protein sequences observed in different genetic lineages of human immunodeficiency virus type 1. J. Virol. 68:6730-6744
21. Korber, B. T. M., S. Osmanov, J. Esparza, G. Myers, and the WHO Network for HIV Isolation and Characterisation. 1994. The World Health Organization Global Programme on AIDS proposal for standardization of HIV sequence nomenclature. AIDS Res Hum. Retroviruses 16:1355-1358
22. Kostrikis, L. G., E. Bagdades, Y. Cao, L. Zhang, D. Dimitriou, and D. D. Ho. 1995. Genetic analysis of human immunodeficiency virus type 1 strains from patients in Cyprus, identification of a new subtype designated subtype 1 J. Virol. 69:6122-6130.
23. Kostrikis, L. G., Y. Cao, H. Ngai, J. P. Moore, and D. D. Ho. 1996. Quantitative analysis of serum neutralization of human immunodeficiency virus type 1 from subtypes A. B. C. D. E. F. and I lack of direct correlation between neutralization serotypes and genetic subtypes and evidence for prevalent serum-dependent infectivity enhancement. J. Virol. 70:445-458
24. Koup, R. A., J. T. Safrit, Y. Cao, C. A. Andrews, G. McLeod, W. Borkowsky, C. Farthing, and D. D. Ho. 1994. Temporal association of cellular immune response with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68:4650-4655.
25. Louwagie, J., E. L. Delwart, J. I. Mullins, F. E. MeCutchan, G. Eddy, and D. S. Burke. 1994. Genetic analysis of HIV-1 isolates from Brazil reveals presence of two distinct genetic subtypes, AIDS Res. Hum. Retroviruses 10:561-567
26. Louwagie, J., W. Janssens, J. Mascola, L. Hevndrickx, P. Hegerich, G. van der Groen, F. E. McCutchan, and D. S. Burke. 1995. Genetic drversity of the envelope glycoprotein from human immunodeficiency viras type 1 isolates of African origin. J. Virol. 69:262-271.
27. Louwagie, J., F. McCutehan, M. Peeters, T. P. Brennan, E. Sanders-Bufll, G. Eddy, G. van der Groen, K. Fransen, G.-M. Gershy-Damet, R. DeLeys, and D. S. Burke. 1993. Comparison of gag genes from seventy international HIV-1 isolates provides evidence for multiple genetic subtypes. AIDS 7:769-780.
28. Mascola, J. R., J. Louwagie, F. E. McCutehan, C. L. Fischer, P. A. Hegerich, K. F. Wagner, A. K. Fowler, J. G. McNeil, and D. S. Burke. 1994. Two antigenically distinct subtypes of HIV-1: viral genotype predicts neutralization serotype. J. Infect Dis. 169:48-54.
29. Matthews, T. J. 1994. Dilemma of neutralization resistance of HIV-1 field isolates and vaccine development. AIDS Res. Hum. Retroviruses 10:631-632.
30. McCutehan, F. E., P. A. Hegerich, T. P. Brennan, P. Phanuphak, P. Singharaj, A. Jugsudee, P. W. Berman, A. M. Gray, A. K. Fowler, and D. S. Burke. 1992 Genetic variants of HIV-1 in Thailand. AIDS Res. Hum. Retroviruses 8:1887-1895.
31. Moore, J. P. 1993. The reactivities of HIV-1 + human sera with solid-phase V3 loop peptides can be poor predictors of their reactivities with V3 loops on native gp120 molecules. AIDS Res. Hum. Retroviruses 9:209-219.
32. Moore, J. P., Y. Cao, U. D. Ho, and R. A. Koup. 1994. Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1. J. Virol. 68:5142-5155.
33. Moore, J. P., Y. Cao, L. Qing, Q. J. Sattentau, J. Pyati, R. Koduri, J. Robinson, C. F. Barbas III, D. R. Burton, and D. D. Ho. 1995. Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120. J. Virol. 69:101-109.
34. Moore, J. P., and D. D. Ho. 1993. Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 arc highly prevalent in sera of infected humans J. Virol. 67:863-875.
35. Moore, J. P., and D. D. Ho. 1995. HIV-1 neutralization: the consequence of viral adaptation to growth on transformed T-cells. AIDS 9:S117-S136.
36. Moore, J. P., F. E. McCutehan, S.-W. Poon, J. Mascola, J. Liu, Y. Cao, and D. D. Ho. 1994. Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies. J. Virol. 68:8350-8364.
37. Moore, J. P., A. Trkola, B. Korber, L. J. Bouts, J. A. Kessler II, F. E. McCutehan, J. Mascola, D. D. Ho, J. Robinson, and A. J. Conley. 1995 A human monoclonal antibody to a complex epitope in the V3 region of human immunodeficiency virus type 1 has broad reactivity within and outside clade B. J. Virol. 69:122-130.
38. Moore, J. P., H. Yoshiyama, D. D. Ho, J. E. Robinson, and J. Sodroski. 1993. Antigenic variation in gp120s from molecular clones of HIV-1 LAT. AIDS Res. Hum Retioviruses 9:1179-1187.
39. Morgado, M. G., E. C. Sabino, E. G. Shpaer, V. Bongertz, L. Brigido, M. D. C. Guimaraes, E. A. Castilho, B. Galvao-Castro, J. I. Mullins, R. M. Hendry, and A. Mayer. 1994. V3 region polymorphisms in HIV-1 from Brazil: prevalence of subtype B strains divergent from North American/ European prototype and detection of subtype F. AIDS Res Hum. Retroviruses, 10:569-576.
40. Myers, G. 1994. HIV. between past and future. AIDS Res. Hum. Relroviruses 10:1317-1324.
41. Myers, G., B. Korber, J. A. Berzofsky, R. F. Smith, and G. N. Pavlakis. 1994. Human retroviruses and AIDS. A compilation and analysis of nucleic acid and amino acid sequences. Los Alamos National Laboratory, Los Alamos, N.Mex
42. Ou, C.-Y., Y. Takebe, B. G. Weniker, C.-C. Luo, M. L. Kalish, W. Auwanit, S. Yamazaki, H. D. Gayle, N. L. Young, and G. Schochetman. 1993. Independent introduction of two major HIV-1 genotypes into distinct high-risk populations in Thailand Lancet 341:1171-1174.
43. Pau, C.-P., M. Kai, D. L. Holloman-Candal, C.-C. Luo, M. L. Kalish, G. Schochetman, B. Byers, J. R. George, and the WHO Network for HIV Isolation and Characterisation. 1994. Antigenic variation and serotyping of HIV-1 from four WHO-sponsored HIV vaccine sites. AIDS Res. Hum. Retroviruses 10:1369-1378.
44. Potts, K. E., M. L. Kalish, T. Lott, G. Orloff, C.-C. Luo, M. A. Bernard. C. B. Alves, R. Badaro, J. Suleiman, O. Ferreira, G. Scbochetman, W. D. Johnson, Jr., C.-Y. Ou, J. L. Ho, and the Brazilian Collaborative AIDS Research Group. 1993. Genetic heterogeneity of the V3 region of the HIV-1 envelope glycoprotein in Brazil AIDS 7:1191-1197.
45. Rübsamen-Waigmann, H., H. von Briesen, H. Holmes, A. Björndal, B. Korber, R. Esser, S. Ranjbar, P. Tomlinson, B. Galvao-Castro, E. Karita, S. Sempala, C. Wasi, S. Osmanoz, E. M. Fenyö, and the WHO Network for HIV Isolation and Characterisation. 1994. Standard conditions of virus isolation reveal biological variability of HIV-1 in different regions of the world AIDS Res. Hum. Retroviruses 10:1401-1408.
46. Sattentau, Q. J., and J. P. Moore. 1995. Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the glycoprotein gp120 oligomer. J. Exp. Med. 182:185-196.
47. Schrager, L. K., J. M. Young, M. G. Fowler, B. J. Mathieson, and S. H. Vermund. 1994. Long-term survivors of HIV-1 infection: definitions and research challenges. AIDS 8(Suppl. 1):S95-S108.
48. Sharp, P. M., D. L. Robertson, F. Gao, and B. H. Hahn. 1994. Origins and diversity of human immunodeficiency viruses. AIDS 8(Suppl. 1):S27-S42.
49. Trkola, A., A. Females, H. Yuan, B. Korber, P. J. Maddon, G. Allaway, H. Katinger, C. F. Barbas III, D. R. Burton, D. D. Ho, and J. P. Moore. 1995 Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IsG J. Virol. 69:6609-6617
50. Trkola, A., D. D. Ho, J. P. Moore, and R. I. Connor. Unpublished data
51. VanCott, T. C., F. R. Bethke, A. W. Artenstein, F. E. McCutchan, J. G. McNeil, J. R. Mascola, R. R. Redfield, and D. L. Birx. 1994 Serotyping international HIV-1 isolates by V3 peptides and whole gp160 proteins using BIAcore. Methods 6:188-198.
52. Vanden Haesevelde, M., J.-L. Cecourt, R. J. De Leys, B. Vanderborght, G. van der Groen, H. van Heuverswijn, and E. Saman. 1994. Genomic cloning and complete sequence analysis of a highly divergent African human immunodeficiency virus isolate. J. Virol. 68:1586-1590.
53. Weber, J. N., E.-M. Fenyö, P. L. Nara, and the WHO Network for HIV Isolation and Characterisation. Neutralisation serotypes of HIV-1 field isolates are not predicted by genetic subtypes. Submitted for publication
54. Weiss, R. A., P. R. Clapham, J. N. Weber, A. G. Datgleish, L. A. Lasky, and P. W. Berman. 1986 Variable and conserved neutralisation antigens of HIV Nature (London) 324:572-575.
55. Weniger, B. G., K. Limpakarnjanarat, K. Ungchusak, S. Thanprasertsuk, K. Choopanya, S. Vanichseni, T. Uneklabh, P. Thongcharoen, and C. Wasi. 1991. The epidemiology of HIV infection and AIDS in Thailand. AIDS 5 (Suppl. 2):S71-S86.
56. WHO Network for HIV Isolation and Characterisation. 1994. HIV-1 variation in WHO-sponsored vaccine-evaluation sites: genetic screening, sequence analysis and preliminary biological characterization of selected viral strains. AIDS Res. Hum Retroviruses 10:1327-1344
57. Wrin, T., L. Crawford, L. Sawyer, P. Weber, H. W. Sheppard, and C. V. Hanson. 1994. Neutralizing antibody response to autologous and heterologous isolates of human immunodeficiency virus J. Acquired Immune Defic. Syndr 7:211-219
58. M recombinant gp120 vaccine serum, which fails to neutralize primary isolates of HIV-1, does not antagonize neutralization by antibodies from infected individuals. AIDS 8:1822-1623.
59. Yahi, N., J. Fantini, I. Hirsch, and J.-C. Chermann. 1992. Structural variability of env and gag gene products from a highly cytopathic strain of HIV-1 Arch. Virol 125:287-298.
60. Zhong, P., M. Peeters, W. Janssens, K. Fransen, L. Heyndrickx, G. Vanham, B. Willems, P. Piot, and G. van der Groeu. 1995. Correlation between genetic and biological properties of biologically cloned HIV type 1 viruses representing subtypes A, B, and D AIDS Res. Hum. Retroviruses 11:239-248
61. Zolla-Pazner, S., J. O'Leary, S. Burda, M. K. Gorny, M. Kim, J. Masiola, and F. McCutchan. 1995. Serolypmg of primary human immunodeticiency virus type 1 isolates from diverse geographic locations by flow cytometry. J. Virol 69:3807-3815.