-
1
-
-
0002941489
-
The neurofibrillary pathology of Alzheimer's disease
-
Edited by SB Prusiner, S DiMauro, RL Barchi. Boston, Butterworth Heineman Press
-
Goedert M, Trojanowski JQ, Lee VM-Y: The neurofibrillary pathology of Alzheimer's disease. The Molecular and Genetic Basis of Neurological Disease, ed. 2. Edited by SB Prusiner, S DiMauro, RL Barchi. Boston, Butterworth Heineman Press, 1997, pp 613-628
-
(1997)
The Molecular and Genetic Basis of Neurological Disease, Ed. 2.
, pp. 613-628
-
-
Goedert, M.1
Trojanowski, J.Q.2
Lee, V.M.-Y.3
-
2
-
-
0002275922
-
Implications of tau-rich neurofibrillary lesions for the pathobiology and diagnosis of Alzheimer's disease
-
Edited by S Appel. Mosby-Year Book, St. Louis
-
Trojanowski JQ, Clark CM, Schmidt ML, Aral H, Zhu C, Mawal-Dewan M, Lee VM-Y: Implications of tau-rich neurofibrillary lesions for the pathobiology and diagnosis of Alzheimer's disease. Current Neurology. Edited by S Appel. Mosby-Year Book, St. Louis, 1996, pp 93-113
-
(1996)
Current Neurology
, pp. 93-113
-
-
Trojanowski, J.Q.1
Clark, C.M.2
Schmidt, M.L.3
Aral, H.4
Zhu, C.5
Mawal-Dewan, M.6
Lee, V.M.-Y.7
-
3
-
-
0028170818
-
Cell biology of the amyloid -protein precursor and the mechanism of Alzheimer's disease
-
Selkoe DJ: Cell biology of the amyloid -protein precursor and the mechanism of Alzheimer's disease. Annu Rev Cell Biol 1994, 10:373-403
-
(1994)
Annu Rev Cell Biol
, vol.10
, pp. 373-403
-
-
Selkoe, D.J.1
-
4
-
-
0028833215
-
Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ
-
Lassmann H, Bancher C, Breitschopf H, Wegiel J, Bobinski M, Jellinger K, Wisniewski HM: Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ. Acta Neuropathol 1995, 89:35-41
-
(1995)
Acta Neuropathol
, vol.89
, pp. 35-41
-
-
Lassmann, H.1
Bancher, C.2
Breitschopf, H.3
Wegiel, J.4
Bobinski, M.5
Jellinger, K.6
Wisniewski, H.M.7
-
5
-
-
0029302244
-
Apoptosis in the brain
-
Dickson DW: Apoptosis in the brain. Am J Pathol 1995, 146:1040-1044
-
(1995)
Am J Pathol
, vol.146
, pp. 1040-1044
-
-
Dickson, D.W.1
-
6
-
-
0029417023
-
Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro
-
Busciglio J, Yankner BA: Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. Nature 1996, 378:776-779
-
(1996)
Nature
, vol.378
, pp. 776-779
-
-
Busciglio, J.1
Yankner, B.A.2
-
7
-
-
0029877684
-
Correlations between mental state and quantitative neuropathology in the Vienna longitudinal study on dementia
-
Bancher C, Jellinger K, Lassmann H, Fischer P, LebIhuber F: Correlations between mental state and quantitative neuropathology in the Vienna longitudinal study on dementia. Eur Arch Psychiatry Clih Neurosci 1996, 240:137-146
-
(1996)
Eur Arch Psychiatry Clih Neurosci
, vol.240
, pp. 137-146
-
-
Bancher, C.1
Jellinger, K.2
Lassmann, H.3
Fischer, P.4
Lebihuber, F.5
-
8
-
-
0029811105
-
Specific domains of β-amyloid from Alzheimer plaque elicit neuron killing in human microglia
-
Giulian D, Haverkamp LJ, Yu JH, Karshin W, Tom D, Li J, Kirkpatrick J, Kuo Y-M, Rohrer AE: Specific domains of β-amyloid from Alzheimer plaque elicit neuron killing in human microglia. J Neurosci 1996, 16:6021-6037
-
(1996)
J Neurosci
, vol.16
, pp. 6021-6037
-
-
Giulian, D.1
Haverkamp, L.J.2
Yu, J.H.3
Karshin, W.4
Tom, D.5
Li, J.6
Kirkpatrick, J.7
Kuo, Y.-M.8
Rohrer, A.E.9
-
9
-
-
0029117593
-
Sulfonated dyes attenuate the toxic effects of β-amyloid in a structure-specific fashion
-
Pollak SJ, Sadler IIJ, Hawtin SR, Tailor VJ, Shearman MS: Sulfonated dyes attenuate the toxic effects of β-amyloid in a structure-specific fashion. Neurosci Lett 1995, 197:211-214
-
(1995)
Neurosci Lett
, vol.197
, pp. 211-214
-
-
Pollak, S.J.1
Iij, S.2
Hawtin, S.R.3
Tailor, V.J.4
Shearman, M.S.5
-
10
-
-
0028982103
-
The toxicity in vitro of β-amyloid protein
-
Iversen LL, Mortishire-Smith RJ, Pollak SJ, Shearman MS: The toxicity in vitro of β-amyloid protein. Biochem J 1995,311:1-16
-
(1995)
Biochem J
, vol.311
, pp. 1-16
-
-
Iversen, L.L.1
Mortishire-Smith, R.J.2
Pollak, S.J.3
Shearman, M.S.4
-
11
-
-
33847478414
-
Amyloid fibril toxicity and tau hyperphos-phorylation in Alzheimer's diseasecell culture and animal models
-
Yankner BA: Amyloid fibril toxicity and tau hyperphos-phorylation in Alzheimer's disease: cell culture and animal models. ISN Satellite Meeting 1995, pp 62-66
-
(1995)
ISN Satellite Meeting
, pp. 62-66
-
-
Yankner, B.A.1
-
12
-
-
0021867264
-
The structure, biochemical properties and immunogenicity of neurofilament peripheral regions are determined by phosphorylation
-
Garden MJ, Schlaepfer WW, Lee VM-Y: The structure, biochemical properties and immunogenicity of neurofilament peripheral regions are determined by phosphorylation. J Biol Chem 1985, 260:9805-9817
-
(1985)
J Biol Chem
, vol.260
, pp. 9805-9817
-
-
Garden, M.J.1
Schlaepfer, W.W.2
Lee, V.M.-Y.3
-
13
-
-
0022512277
-
Structural similarities and differences between neurofilament proteins from five different species as revealed by monoclonal antibodies
-
Lee VM-Y, Garden MJ, Schlaepfer WW: Structural similarities and differences between neurofilament proteins from five different species as revealed by monoclonal antibodies. J Neurosci 1986, 6:2179-2186
-
(1986)
J Neurosci
, vol.6
, pp. 2179-2186
-
-
Lee, V.M.-Y.1
Garden, M.J.2
Schlaepfer, W.W.3
-
14
-
-
0022642328
-
Novel monoclonal antibodies provide evidence for the in situ existence of a non-phosphorylated form of the largest neurofilament subunit
-
Lee VM-Y, Garden MJ, Trojanowski JQ: Novel monoclonal antibodies provide evidence for the in situ existence of a non-phosphorylated form of the largest neurofilament subunit. J Neurosci 1986, 6:850-858
-
(1986)
J Neurosci
, vol.6
, pp. 850-858
-
-
Lee, V.M.-Y.1
Garden, M.J.2
Trojanowski, J.Q.3
-
15
-
-
0021330771
-
Monoclonal antibodies to gel excised glial filament protein and their reactivity with other intermediate filaments
-
Lee VM-Y, Page CD, Wu H-L, Schlaepfer WW: Monoclonal antibodies to gel excised glial filament protein and their reactivity with other intermediate filaments. J Neurochem 1984, 42:25-32
-
(1984)
J Neurochem
, vol.42
, pp. 25-32
-
-
Lee, V.M.-Y.1
Page, C.D.2
Wu, H.-L.3
Schlaepfer, W.W.4
-
16
-
-
0027308924
-
Abnormal tau phosphorylation at ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
-
Bramble GT, Goedert M, Jakes R, Merrick SE, Trojanowski JQ, Lee VM-Y: Abnormal tau phosphorylation at ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding. Neuron 1993, 10:1089-1099
-
(1993)
Neuron
, vol.10
, pp. 1089-1099
-
-
Bramble, G.T.1
Goedert, M.2
Jakes, R.3
Merrick, S.E.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
17
-
-
0027236786
-
Alzheimer disease A68 proteins injected into rat brain induce codeposits of β-amyloid, ubiquitin and a1-antichymotrypsin
-
Shin R-W, Bramblett GT, Lee VM-Y, Trojanowski JQ: Alzheimer disease A68 proteins injected into rat brain induce codeposits of β-amyloid, ubiquitin and a1-antichymotrypsin. Proc Natl Acad Sci USA 1993, 90:68256828
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 68256828
-
-
Shin, R.-W.1
Bramblett, G.T.2
Lee, V.M.-Y.3
Trojanowski, J.Q.4
-
18
-
-
0026501888
-
Hydrofluoric acid-treated TPHF proteins display the same biochemical properties as normal T
-
Greenberg SG, Davies P, Schein JD, Binder LI: Hydrofluoric acid-treated TPHF proteins display the same biochemical properties as normal T. J Biol Chem 1992, 267:564-569
-
(1992)
J Biol Chem
, vol.267
, pp. 564-569
-
-
Greenberg, S.G.1
Davies, P.2
Schein, J.D.3
Binder, L.I.4
-
19
-
-
0026611728
-
Immunological and conformational characterization of a phosphorylated immunodominant epitope on the paired helical filaments found in Alzheimer's disease
-
Lang E, Szendrei Gl, Lee VM-Y, Otvos L Jr: Immunological and conformational characterization of a phosphorylated immunodominant epitope on the paired helical filaments found in Alzheimer's disease. Biochem Biophys Res Commun 1992, 187:783-790
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 783-790
-
-
Lang, E.1
Szendrei, G.2
Lee, V.M.-Y.3
Otvos Jr., L.4
-
20
-
-
0025904444
-
A68: A major subunit of paired helical filaments and derivatized forms of normal tau
-
Lee VM-Y. Balin BJ, Otvos L Jr, Trojanowski JQ: A68: a major subunit of paired helical filaments and derivatized forms of normal tau. Science 1991, 251:675-678
-
(1991)
Science
, vol.251
, pp. 675-678
-
-
Lee, V.M.-Y.1
Balin, B.J.2
Otvos Jr., L.3
Trojanowski, J.Q.4
-
21
-
-
0029664624
-
Amyloids β40 and 042 are generated intracellularly in cultured human neurons, and their secretion increases with maturation
-
Turner RS, Suzuki N, Chyung AS, Younkin SG, Lee VM-Y: Amyloids β40 and 042 are generated intracellularly in cultured human neurons, and their secretion increases with maturation. J Biol Chem 1996, 271: 8966-8970
-
(1996)
J Biol Chem
, vol.271
, pp. 8966-8970
-
-
Turner, R.S.1
Suzuki, N.2
Chyung, A.S.3
Younkin, S.G.4
Lee, V.M.-Y.5
-
22
-
-
0028630738
-
Plaque-associated neuronal proteinsa recurrent motif in neuritic amyloid deposits throughout diverse cortical areas of the Alzheimer's disease brain
-
Schmidt ML, DiDario AG, Otvos L Jr, Hoshi N, Kant A, Lee VM-Y, Trojanowski JQ: Plaque-associated neuronal proteins: a recurrent motif in neuritic amyloid deposits throughout diverse cortical areas of the Alzheimer's disease brain. Exp Neurol 1994, 130:311-322
-
(1994)
Exp Neurol
, vol.130
, pp. 311-322
-
-
Schmidt, M.L.1
Didario, A.G.2
Otvos Jr., L.3
Hoshi, N.4
Kant, A.5
Lee, V.M.-Y.6
Trojanowski, J.Q.7
-
23
-
-
0023916455
-
Bai C, Grundke-lqbal I, Currie JR, Wisniewski HMProduction and characterization of monoclonal antibodies reactive to synthetic cerebrovascular amyloid peptide
-
Kirn KS, Miller DL, Sapienza VJ, Chen CJ. Bai C, Grundke-lqbal I, Currie JR, Wisniewski HM: Production and characterization of monoclonal antibodies reactive to synthetic cerebrovascular amyloid peptide. Neurosci Res Commun 1988, 2:121-130
-
(1988)
Neurosci Res Commun
, vol.2
, pp. 121-130
-
-
Kirn, K.S.1
Miller, D.L.2
Sapienza, V.J.3
Chen, C.J.4
-
24
-
-
0025013745
-
Detection and quantitation of amyloid β peptide with 2 monoclonal antibodies
-
Kim KS, Wen GY, Bancher C, Chen CMJ, Sapienza VJ, Hong H, Wisniewski HM: Detection and quantitation of amyloid β peptide with 2 monoclonal antibodies. Neurosci Res Commun 1990, 9:113-122
-
(1990)
Neurosci Res Commun
, vol.9
, pp. 113-122
-
-
Kim, K.S.1
Wen, G.Y.2
Bancher, C.3
Cmj, C.4
Sapienza, V.J.5
Hong, H.6
Wisniewski, H.M.7
-
25
-
-
0025289562
-
Large amounts of neocortical β/A4 deposits without neuritic plaques nor tangles in a psy-. chometrically assessed, nondemented person
-
Delaere P, Duyckaerts C, Masters CL, Beyreuther K, Piette F, Hauw JJ: Large amounts of neocortical β/A4 deposits without neuritic plaques nor tangles in a psy-. chometrically assessed, nondemented person. NeurosciLett 1990, 116:87-93
-
(1990)
NeurosciLett
, vol.116
, pp. 87-93
-
-
Delaere, P.1
Duyckaerts, C.2
Masters, C.L.3
Beyreuther, K.4
Piette, F.5
Hauw, J.J.6
-
26
-
-
0026512066
-
Identification of normal and pathologic aging in prospectively studied nondemented elderly humans
-
Dickson DW, Crystal HA, Mattiace LA, Masur DM, Blau A, Davies P, Yen S-H, Aronson MK: Identification of normal and pathologic aging in prospectively studied nondemented elderly humans. Neurobiol Aging 1991, 13:179-189
-
(1991)
Neurobiol Aging
, vol.13
, pp. 179-189
-
-
Dickson, D.W.1
Crystal, H.A.2
Mattiace, L.A.3
Masur, D.M.4
Blau, A.5
Davies, P.6
Yen, S.-H.7
Aronson, M.K.8
-
27
-
-
0030004466
-
Convergence of Lewy bodies and neurofibrillary tangles in amygdala neurons of Alzheimer's disease and Lewy body disorders
-
Schmidt ML, Martin JA, Lee VM-Y, Trojanowski JQ: Convergence of Lewy bodies and neurofibrillary tangles in amygdala neurons of Alzheimer's disease and Lewy body disorders. Acta Neuropathol 1996, 91:475-481
-
(1996)
Acta Neuropathol
, vol.91
, pp. 475-481
-
-
Schmidt, M.L.1
Martin, J.A.2
Lee, V.M.-Y.3
Trojanowski, J.Q.4
-
28
-
-
0029971280
-
Neurofibrillary tangles in progressive supranuclear palsy contain the same epitopes identified in Alzheimer's disease PHF-tau
-
Schmidt ML, Huang R, Martin JA, Henley J, MawalDewan M, Hurtig HI, Lee VM-Y, Trojanowski JQ: Neurofibrillary tangles in progressive supranuclear palsy contain the same epitopes identified in Alzheimer's disease PHF-tau. J Neuropathol Exp Neurol 1996, 55: 534-539
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 534-539
-
-
Schmidt, M.L.1
Huang, R.2
Martin, J.A.3
Henley, J.4
Mawaldewan, M.5
Hurtig, H.I.6
Lee, V.M.-Y.7
Trojanowski, J.Q.8
-
30
-
-
0028853478
-
DiFiglia M, McKee AC, MacDonald M, Gusella JF, Landwhermeyer GB, Bird ED, Richardson EP Jr, Hedley-Whyte ETAn improved approach to prepare human brain for research
-
Vonsattel JP, Aizawa H, Ge P. DiFiglia M, McKee AC, MacDonald M, Gusella JF, Landwhermeyer GB, Bird ED, Richardson EP Jr, Hedley-Whyte ET: An improved approach to prepare human brain for research. J Neuropathol Exp Neurol 1995, 54:42-56
-
(1995)
J Neuropathol Exp Neurol
, vol.54
, pp. 42-56
-
-
Vonsattel, J.P.1
Aizawa, H.2
Ge, P.3
-
31
-
-
0025345913
-
Relative abundance of tau and neurofilament epitopes in hippocampal neurofibrillary tangles
-
Schmidt ML, Lee VM-Y, Trojanowski JQ: Relative abundance of tau and neurofilament epitopes in hippocampal neurofibrillary tangles. Am J Pathol 1990, 136: 1069-1075
-
(1990)
Am J Pathol
, vol.136
, pp. 1069-1075
-
-
Schmidt, M.L.1
Lee, V.M.-Y.2
Trojanowski, J.Q.3
-
32
-
-
0025905505
-
Comparative epitope analysis of neuronal cytoskeletal proteins in Alzheimer's disease senile plaque neurites and neuropil threads
-
Schmidt ML, Lee VM-Y, Trojanowski JQ: Comparative epitope analysis of neuronal cytoskeletal proteins in Alzheimer's disease senile plaque neurites and neuropil threads. Lab Invest 1991, 64:352-357
-
(1991)
Lab Invest
, vol.64
, pp. 352-357
-
-
Schmidt, M.L.1
Lee, V.M.-Y.2
Trojanowski, J.Q.3
-
33
-
-
0029087813
-
Chemical and immunological heterogeneity of fibrillar amyloid in plaques of Alzheimer's disease and Down's syndrome brains revealed by confocal microscopy
-
Schmidt ML, Robinson KA, Lee VM-Y, Trojanowski JQ: Chemical and immunological heterogeneity of fibrillar amyloid in plaques of Alzheimer's disease and Down's syndrome brains revealed by confocal microscopy. Am J Pathol 1995, 147:503-515
-
(1995)
Am J Pathol
, vol.147
, pp. 503-515
-
-
Schmidt, M.L.1
Robinson, K.A.2
Lee, V.M.-Y.3
Trojanowski, J.Q.4
-
34
-
-
0027945346
-
Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau
-
Matsuo ES, Shin R-W, Billingsley ML, Van de Voorde A, O'Connor M, Trojanowski JQ, Lee VM-Y: Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau. Neuron 1994, 13:989-1002
-
(1994)
Neuron
, vol.13
, pp. 989-1002
-
-
Matsuo, E.S.1
Shin, R.-W.2
Billingsley, M.L.3
Van De Voorde, A.4
O'Connor, M.5
Trojanowski, J.Q.6
Lee, V.M.-Y.7
-
35
-
-
0029823961
-
Identification of phosphorylation sites in PHF-TAU from patients with Guam amyotrophic lateral sclerosis/Parkinsonism-dementia complex
-
Mawal-Dewan M, Schmidt ML, Baiin B, Perl DP, Lee VM-Y, Trojanowski JQ: Identification of phosphorylation sites in PHF-TAU from patients with Guam amyotrophic lateral sclerosis/Parkinsonism-dementia complex. J Neuropathol Exp Neurol 1996, 55:10511059
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 10511059
-
-
Mawal-Dewan, M.1
Schmidt, M.L.2
Baiin, B.3
Perl, D.P.4
Lee, V.M.-Y.5
Trojanowski, J.Q.6
-
36
-
-
0026578425
-
Regions with abundant neurofibrillary pathology in human brain exhibit a selective reduction in levels of binding-competent T and accumulations of abnormal r-isoforms (A68 proteins)
-
Bramblett GT, Trojanowski JQ, Lee VM-Y: Regions with abundant neurofibrillary pathology in human brain exhibit a selective reduction in levels of binding-competent T and accumulations of abnormal r-isoforms (A68 proteins). Lab Invest 1992, 66:212-222
-
(1992)
Lab Invest
, vol.66
, pp. 212-222
-
-
Bramblett, G.T.1
Trojanowski, J.Q.2
Lee, V.M.-Y.3
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