Apoptosis and increased generation of reactive oxygen species in down’s syndrome neurons in vitro

Nature

Volumn 378, Issue 6559, 1995, Pages 776-779

  Busciglio, Jorge ^a   Yankner, Bruce A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE; CATALASE; LIPID; SCAVENGER;

APOPTOSIS; DOWN SYNDROME; IN VITRO STUDY; NERVE CELL; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; FETUS; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; PRIORITY JOURNAL;

ALZHEIMER DISEASE; ANTIOXIDANTS; APOPTOSIS; CELL DIFFERENTIATION; CELLS, CULTURED; CEREBRAL CORTEX; CYCLOHEXIMIDE; DACTINOMYCIN; DOWN SYNDROME; FLUORESCEINS; FREE RADICAL SCAVENGERS; HUMANS; LIPID PEROXIDATION; NERVE DEGENERATION; NEURONS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

LETHRINIDAE;

EID: 0029417023     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/378776a0     Document Type: Article

References (26)

1. Coyle, J. T., Oster-Granite, M. L. & Gearhart, J. D. Brain Res. Bull. 16, 773-787 (1986).
2. Colon, E. J. Neuropediatrics 3, 362-376 (1972).
3. Marin-Padilla, M. Brain Res. 44, 625-629 (1972).
4. Takashima S., Becker, L. E., Armstrong, D. & Chen, T. Brain Res. 225, 1-21 (1981).
5. Ross, M. H., Galaburda, A. M. & Kemper, T. L. Neurology 34, 909-916 (1984).
6. Wisniewski, K. E., Laure-Kamionowska, M., Connell, F. & Wen, G. Y. The Neurobiology of Down Syndrome 29-44 (Raven, New York, 1986).
7. Becker, L, Mito, T., Takashima, S. & Onodera, K. Prog. din. biol. Res. 373, 133-152 (1991).
8. Mann, D. M. A. Mech. Ageing Dev. 43, 99-136 (1988).
9. Lai, F. & Williams, R. S. Arch. Neurol. 46, 849-853 (1989).
10. Busciglio, J., Yeh, J. & Yankner, B. A. J. Neurochem. 61, 1565-1568 (1993).
11. Wyllie, A. H., Kerr, F. F. R. & Currie, A. R. Int. Rev. Cytol. 68, 251-306 (1980).
12. Brooksbank, B. W. L. & Balazs, R. Dev. Brain Res. 16, 37-44 (1984).
13. Kedziora, J. & Bartosz, G. Free Rad. Biol. Med. 4, 317-330 (1988).
14. Cathcart, R., Schwiers, E. & Ames, B. N. Analyt. Biochem. 134, 111-116 (1983).
15. Bass, D. A. et al. J. Immun. 130, 1910-1917 (1983).
16. Royall, J. A. & Ischiropoulus, H. Arch. Biochem. Biophys. 302, 348-355 (1993).
17. Hedley, D. & Chow, S. Cytometry 13, 686-692 (1992).
18. Kane, D. J. et al. Science 262, 1274-1277 (1993).
19. Greenlund, L. J. S., Deckwerth, T. L. & Johnson, E. M. Jr Neuron 14, 303-315 (1995).
20. Koh, J.-Y., Gwag, B. J., Lobner, D. & Choi, D. W. Science 268, 573-575 (1995).
21. Jacobson, M. D. & Raff, M. C. Nature. 374, 814-816 (1995).
22. Shimizu, S. et al. Nature 374, 811-813 (1995).
23. Petit, T. L, LeBoutillier, J. C., Alfano, D. P. & Becker, L. E. Expl Neurol. 83, 13-23 (1984).
24. Smith C. D. et al. Proc natn. Acad. Sei. U.S.A. 88, 10540-10543 (1991).
25. Mecocci, P., Mac Garvey, U. & Beal, M. F. Ann. Neurol. 36, 747-751 (1994).
26. Busciglio, J., Gabuzda, D. H., Matsudaira, P. & Yankner, B. A. Proc. natn. Acad. Sei. U.S.A. 90, 2092-2096 (1993).