Biologically active fungal metabolites

Advances in Applied Microbiology

Volumn 44, Issue , 1997, Pages 1-80

  Pearce, C ^a  

^a MYCOsearch   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; ENZYME INHIBITOR; NATURAL PRODUCT;

BIODIVERSITY; BIOSYNTHESIS; DRUG ACTIVITY; FUNGUS; METABOLITE; NONHUMAN; ORGANIC CHEMISTRY; REVIEW; STRUCTURE ACTIVITY RELATION;

APUS APUS; FUNGI;

EID: 0030870059     PISSN: 00652164     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0065-2164(08)70459-3     Document Type: Review

References (196)

1. A.M. Ainsworth M.I. Chicarelli-Robinson B.R. Copp U. Fauth P.J. Hylands J.A. Holloway M. Latif G.B. O’Beirne N. Porter D.V. Renno M. Richards N. Robinson Xenovulene A, a novel GABA-benzodiazapine receptor binding compound produced by Acremonium strictum J. Antibiot. 48 1995 568 573
2. A.W. Alberts J. Chen G. Kuron V. Hunt J. Huff C. Hoffman J. Rothcock M. Lopez H. Joshua E. Harris A. Patchett R. Monaghan S. Currie E. Stapley G. Albers-Schonberg O. Hensens J. Hirshfield K. Hoogsteen J. Liesch J. Springer Mevinolin: A highly potent competitive inhibitor of hydroxymethylglutary-coenzyme A reductase and a cholesterol lowering agent Proc. Natl. Acad. Sci. U.S.A. 77 1980 3957 3961
3. M.G. Anderson T.B. Jarman R.W. Rickards Structures and absolute configurations of antibiotics of the oligosporon group from the nematode-trapping fungus Arthrobotrys oligospora J. Antibiot. 48 1995 391 398
4. T. Anke The antifungal strobilurins and their possible ecological role Can. J. Bot. 73 1995 S940 S945
5. T. Anke A. Werle S. Zapf R. Velten W. Steglich Favolon, a new antifungal triterpenoid from a Favolaschia species Antibiot. 48 1995 725 726
6. Anonymous First launch for Roche’s CellCept Scrip 2036 1995 19 (23 June)
7. F. Aragozzini P.L. Manachini R. Craveri B. Rindone C. Scolastico Isolation and structure determination of a new antifungal a-hydroxymethyl-a-amino acid Tetrahedron 28 1972 5493 5498
8. N. Arai K. Shiomi H. Tomoda N. Tabata D.J. Yang R. Masuma T. Kawakubo S. Omura Isochromophilones III–VI, inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium multicolor FO-3216 J. Antibiot. 48 1995 696 702
9. W. Ayer S. Miao Secondary metabolites of the Aspen fungus Stachybotrys cylindrospora Can. J. Chem. 71 1993 487 493
10. A. Baxter B.J. Fitzgerald J.L. Hutson A.D. McCarthy J.M. Motteram B.C. Ross M. Sapra M.A. Snowden N.S. Watson R.J. Williams C. Wright Squalestatin 1, a potent inhibitor of squalene synthase, which lowers serum cholesterol in vivo J. Biol. Chem. 276 1992 11705 11708
11. G.N. Belofsky J.B. Gloer D.T. Wicklow P.F. Dowd Antiinsectan alkaloids: Shearinines A-C and a new paxilline derivative from the ascostromata of Eupenicillium shearii Tetrahedron 51 1995 3959 3968
12. J.D. Bergstrom M.M. Kurtz D.J. Rew A.M. Amend J.D. Karkas R.G. Bostedao J.I. Germenhausen V.S. Bansal C. Dufresne F.L. VanMiddlesworth O.D. Hensens J.M. Liesch D.L. Zink K.E. Wilson J. Onishi J.A. Milligen G. Bills K.F. Bartizal W. Rozdilsky G.K. Abruzzo L. Kaplan M. Nallin R.G. Jenkins L. Huang M.S. Meinz L. Quinn R.W. Burg Y.L. Kong S. Mochales M. Mojena I. Martin F. Palaez M. Diez A.W. Alberts The zaragozic acids: A family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase Proc. Natl. Acad. Sci. U.S.A. 90 1993 80 84
13. J.D. Bergstrom C. Dufresne G. Bills M. Nallin-Omstead K. Byrne Discovery, biosynthesis, and mechanism of action of the zaragozic acids: Potent inhibitors of squalene synthase Annu. Rev. Microbiol. 49 1995 607 639
14. G. Bills F. Pelaez J.D. Polishook M.T. Diez-Matas G. Harris W.H. Clapp C. Dufresne K.M. Byrne M. Nallin-Omstead R.G. Jenkins M. Mojena L. Huang J.D. Bergstrom Distribution of zaragozic acids (squalestatins) among filamentous ascomycetes Mycol. Res. 98 1994 733 739
15. R.K. Boyd A.J. McAleess A. Taylor J.A. Walker Isolation of new isocyanide metabolites of Trichoderma hamatum as their ( n -5-pentamthylcyclopentadienyl)- or ( n -5-ethyltetramethylcyclopentadienyl)-di-μ-thiocyana-to-rhodium complexes J. Chem. Soc, Perkin Trans 1 1991 1461 1465
16. S. Brandage S. Josephson A. Mahlen L. Morch S. Vallen (-)-Decylcitric acid and (+)-isocitric acid as metabolites from Penicillium spiculisporum —a correction Acta. Chem. Scan. B30 1976 177 187
17. D. Brewer E.J. Gabe A.E. Hanson A. Taylor Isonitrile acids from cultures of the fungus Trichoderma hamatum J. Chem. Soc., Chem. Commun. 1979 1061 1062
18. A.J. Brown T.C. Smale T.J. King R. Hasenkamp R.H. Thompson Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum. J. Chem. Soc, Perkin Trans 1 1976 1165 1170
19. M.E. Bushell The process physiology of secondary metabolite production S. Baumberg I.S. Hunter P.M. Rhodes Microbial Products: New Approaches” 1989 Cambridge Univ. Press Cambridge
20. A.D. Buss R.D. Waigh Natural products as leads for new pharmaceuticals M.E. Wolff Burger’s Medicinal Chemistry and Drug Discovery 5th ed Principles and Practice” 1 1995 Wiley New York 983 1034
21. K.M. Byrne B.H. Arison M. Nallin-Omstead L. Kaplan Biosynthesis of zaragozic acid Org. Chem. 58 1993 1019 1024
22. T.-B. Chen D.D. Weimer Corymbotins A-I: Highly oxidized kolovane derivatives from Casearia corymbosa J. Nat. Prod. 54 1991 1612 1618
23. W.S. Chen C.S. Lazar M. Poenie R.Y. Tsien G.N. Gill M.G. Rosenfeld Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor Nature 328 1987 820 823
24. K.K. Chexal Ch. Tamm J. Clardy K. Hirotsu Gilmaniellin and dechlorogilmaniellin, two novel dimeric oxaphenalenones Helv. Chim. Acta 62 1979 1785 1803
25. M. Chu I. Truumees I. Gunnarsson W.R. Bishop W. Kreutner A. Horan M.G. Patel V.P. Gullo M.S. Puar A novel class of platelet activating factor antagonists from a Phoma sp J. Antibiot. 46 1993 554 563
26. M. Chu I. Truumees M. Patel C. Blood P.R. Das M.S. Puar Sch 50673 and Sch 50676, two novel antitumor fungal metabolites J. Antibiot. 48 1995 329 331
27. M. Chu I. Truumees M.L. Rothofsky M. Patel F. Gentile P.R. Das M.S. Puar S.L. Lin Inhibition of c-fos proto-oncogene induction by Sch 52900 and Sch 52901, novel diketopiperazines produced by Gliocladium sp J. Antibiot. 48 1995 1440 1445
28. J.M. Clough The strobilurins, oudemansins, and myxothiazols, fungicidal derivatives of β-methoxyacrylic acid Nat. Prod. Rep. 10 1993 565 574
29. P.W. Clutterbuck H. Raistrick M.L. Rintoul Studies in the biochemistry of micro-organisms, Part XVI: On the production from Glucose by Penicillium spiculisporum Lehman of a new polybasic fatty acid, C17H2806 (the lactone of γ hydroxy-βδ-dicarboxypentadecoic acid) Trans. Roy. Soc. B220 1931 301 330
30. R.J. Cole R.H. Cox Handbook of Toxic Fungal Metabolites 1981 Academic Press New York
31. N. Connors R. Prevoznak T. Brix A. Seeley R. Gbewonyo R. Greasham P. Salmon Effects of medium sterilization on the production of zaragozic acid by the fungus Leptodontidium elatius J. Ind. Microbiol. 15 1995 503 508
32. S.J. Coval M.S. Puar D.W. Phife J.S. Terracciano M. Patel SCH57404, an antifungal agent possessing the rare sodaricin skeleton and a tricyclic sugar moiety J. Antibiot. 48 1995 1171 1172
33. 2 inhibitors J. Nat. Prod. 59 1996 977 979
34. C.-B. Cui H. Kakeya G. Okada R. Onose M. Ubukata I. Takahashi K. Isono H. Osada Tryprostatins A and B, novel mammalian cell cycle inhibitors produced by Aspergillus flavus J. Antibiot. 48 1995 1382 1384
35. W.L. Current J. Tang C. Boylan P. Watson D. Zeckner W. Turner M. Rodriguez C. Dixon D. Ma J.A. Radding Glucan biosynthesis as a target for antifungals: The echinocandin class of antifungal agents K.G. Dixon L.G. Copping D.W. Holloman Antifungal Agents: Discovery and Mode of Action 1995 BioScientific Publishers Oxford, UK 143 160
36. H.G. Cutler E. Ammerman J.P. Springer Diverse but specific biological activities of four natural products from three fungi H.G. Cutler Biologically Active Natural Products: Potential Use in Agriculture American Chemical Society Symposium Series 380 1988 American Chemical Society Washington, DC 79 90
37. M.J. Dawson J.E. Farthing P.S. Marshall R.F. Middleton M.J. O’Neill A. Shuttleworth C. Stylli R.M. Tait P.M. Taylor H.G. Wildman A.D. Buss D. Langley M.V. Hayes The squalestatins, novel inhibitors of squalene synthase produced by a species of Phoma, I: Taxonomy, fermentation, isolation, physicochemical properties and biological activity J. Antibiot. 45 1992 639 647
38. M. Debono The echinocandins: Fungicides targeted to the fungal cell wall Expert Opin. Invest. Drugs 3 1994 65 82
39. M. Debono Echinocandin lipopeptide antifungal agents: New agents and recent chemical modification studies Expert Opin. Ther. Pat. 5 1995 771 786
40. A.L. Demain Regulation of secondary metabolism D.B. Finklestein C. Ball Biotechnology of Filamentous Fungi: Technology and Products 1992 Butterworth-Heinemann Boston
41. K. Dornberger W. Ihn M. Ritzau U. Grafe B. Schlegel W.F. Fleck Chrysospermins, new peptaibol antibiotics from Apiocrea chrysospermin Ap101 J. Antibiot. 48 1995 977 989
42. M. Dreyfus E. Harri H. Hofmann H. Kobel W. Pache H. Tscherter Cyclosporine A and C, new metabolites from Trichoderma polysporum (Link et Pers.) Rifai Eur. J. Appl. Microbiol. 3 1976 125 133
43. C. Dufresne E.T. Turner-Jones M. Nallin-Omstead J.D. Bergstrom K.E. Wilson Novel zaragozic acids from Leptodontidium elatius J. Nat. Prod. 59 1996 52 54
44. J.A. Elix V.K. Jayanthi C.C. Leznoff 2,4-di-O-methylgyrophoric acid and 2,4,5-tri-O-methylhiascic acid. New tridepsides from Parmelia damaziana Aust. J. Chem. 34 1981 1757 1761
45. A. Endo Monacolin K, a new hypocholesterolemic agent produced by a Monascus species J. Antibiot. 32 1979 852 854
46. A. Endo M. Kuroda Y. Tsujita ML-236A, ML-236B and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinum J. Antibiot. 29 1976 1346 1348
47. M. Engler T. Anke D. Klostermeyer W. Steglich Hydroxystrobilurin A, a new antifungal E-β-methoxyacrylate from a Pterula species J. Antibiot. 48 1995 884 885
48. T. Fehr W. Acklin Die Isolierung zweier neuartiger Indol-derivate aus dem Mycel von Claviceps paspali Stevens et Hall Helv. Chim. Acta 49 1966 1907 1919
49. S.C. Fields L. Mireles-Lo B.C. Gerwick Hydroxycornexistin: A new phytotoxin from Paecilomyces variotii J. Nat. Prod. 59 1996 698 700
50. A. Fleming History and Development of Penicillin 1946 Butterworth London 1 23
51. A. Fredenhagen P. Hug H. Sauter H.H. Peter Paeciloquinones A, B, C, D and F: New potent inhibitors of protein kinase produced by Paecilomyces carneus , II: Characterization and structure determination J. Antibiot. 48 1995 199 204
52. A. Fredenhagen H. Mett T. Meyer E. Buchdunger U. Regenass B. Roggo F. Petersen Protein tyrosine kinase and protein kinase c inhibition by fungal anthraquinones related to emodin J. Antibiot. 48 1995 1355 1358
53. T. Fujita K. Inoue S. Yamamoto T. Ikumoto S. Sasaki R. Toyama K. Chiba Y. Hoshino T. Okumoto Fungal metabolites, Part 11: A potent immunosuppressive activity found in Isaria sinclarii metabolite J. Antibiot. 47 1994 208 215
54. T. Fujita N. Hamamichi M. Kiuchi K. Masatoshi T. Matsuzaki Y. Kitao K. Inoue R. Hirose M. Yoneta S. Sasaki K. Chiba Determination of absolute configuration and biological activity of new immunosuppressants, mycestericins D, E, F and G J. Antibiot. 49 1996 846 853
55. M. Fujiwara T. Okuda S. Masuda Y. Shiomi C. Miyamoto Y. Sekine M. Takoe M. Fujiwara Fermentation, isolation and characterization of isonitrile antibiotics Agric. Biol. Chem. 46 1982 1803 1809
56. L.L. Gallo S.B. Clark S. Meyers G.V. Vahouny Cholesterol absorption in rat intestine: Role of cholesterol esterase and acyl coenzyme A:cholesterol acyltransferase J. Lipid Res 25 1984 604 612
57. S. Gatenbeck A. Mahlen A metabolic variation in Penicillium spiculisporum Lehman, I: Production of (+) and (−) decylcitric acids Acta. Chem. Scan. 22 1968 2613 2616
58. D.R. Gehlert Subtypes of receptors for neuropeptide Y: Implication for targeting of therapeutics Life Sci. 55 1994 551 562
59. J.B. Gibbs RasC-terminal processing enzymes: New drug targets? Cell 65 1991 1 4
60. J.B. Gloer The chemistry of fungal antagonism and defence Can. J. Bot. 73 1995 S1265 S1274
61. J.B. Gloer Antiinsectan natural products from fungal sclerotia Accounts Chem. Res. 28 1995 343 350
62. J.B. Gloer Applications of fungal ecology in the search for new bioactive natural products The Mycota 1996 In press
63. Goodman and Gilman’s the Pharmacological Basis of Therapeutics A. Goodman Gilman L.S. Goodman T.W. Rall F. Murad 7th ed 1985 Macmillan New York 1298 1299
64. C. Goulard S. Hlimi S. Rebuffat B. Bodo Trichorzins HA and MA, antibiotic peptides from Trichoderma harzianum , I: Fermentation, isolation and biological properties J. Antibiot. 48 1995 1248 1253
65. U. Grafe W. Ihn M. Ritzau W. Schade C. Stengel B. Schlegel W.F. Fleck W. Kunkel A. Hartl W. Gutsche Helioferins; Novel antifungal lipopeptides from Mycogone rosea: Screening, isolation, structures and biological properties J. Antibiot. 48 1995 126 133
66. L. Grundemar R. Hakanson Neuropeptide Y effector systems: Perspectives for drug development Trends Pharm. Sci. 15 1994 155 159
67. G.H. Harris K. Hoogsteen K.C. Silverman S.L. Raghoobar G.F. Bills R.B. Lingham J.L. Smith H.W. Dougherty C. Cascales F. Pelaez Isolation and structure determination of pycnidone, a novel bistropolone stromelysin inhibitor from a Phoma sp Tetrahedron 49 1993 2139 2144
68. R. Hashimoto K. Takahashi K. Hamano T. Mori A. Nakagawa New method for screening the melanin biosynthesis inhibitor by using the larval haemolymph of the silkworm, Bombyx mori , and the inhibitory activity of trichoviridin Biosci. Biotech. Biochem. 58 1994 1725 1726
69. R. Hashimoto S. Takehashi K. Hamano A. Nakagawa A new melanin biosynthesis inhibitor, melanoxadin from fungal metabolite by using the larval haemolymph of the silkworm, Bombyx mori J. Antibiot. 48 1995 1052 1054
70. K. Hasumi K. Tachikawa K. Sakai S. Murakawa N. Yoshikawa S. Kumazawa A. Endo Competitive inhibition of squalene synthetase by squalestatin, 1 J. Antibiot. 46 1993 689 691
71. D.L. Hawksworth The fungal dimension of biodiversity: Magnitude, significance, and conservation Mycol. Res. 95 1991 641 655
72. M. Hayashi Y.-P. Kim H. Hiraoka M. Natori S. Takamatsu T. Kawakubo R. Masuma K. Komiyama S. Omura Macrosphelide, a novel inhibitor of cell-cell adhesion molecules, I: Taxonomy, fermentation, isolation and biological activities J. Antibiot. 48 1995 1435 1439
73. S. Hlimi S. Rebuffat C. Goulard S. Duchamp B. Bodo Trichorzins HA and MA, antibiotic peptides from Trichoderma harzianum , II: Sequence determination J. Antibiot. 48 1995 1254 1261
74. J.E. Hochlowski D.N. Whittern A. Buko L. Alder J. McAlpine Fusacandins A and B; Novel antifungal antibiotics of the papuolacandin class from Fusarium sambucinum , II: Isolation and structural elucidation J. Antibiot. 48 1995 614618
75. X.-H. Huang H. Tomoda H. Nishida R. Masuma S. Omura Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis , I: Production, isolation and biological properties J. Antibiot. 48 1995 1 4
76. X.-H. Huang H. Nishida H. Tomoda N. Tabata K. Shiomi D.-J. Yang H. Takayanagi S. Omura Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis , II: Structure elucidation of terpendoles A, B C and D J. Antibiot. 48 1995 5 11
77. M. Ihara T. Fukuroda T. Saeki M. Nishikibe K. Kojiri H. Suda M. Yano An endothelin receptor (ETa) antagonist isolated from Streptomyces misakiensis Biochem. Biophys. Res. Commun. 178 1991 132 137
78. T. Ishimaru S. Tsuboya T. Saijo Tetracyclic compounds, their manufacture with Penicillium or Metarrizium , and inflammation inhibitors containing the tetracyclic compounds 1994 Jpn. Pat. 0640995A.
79. M. Jackson D.J. Frost J.P. Karwowski P.E. Humphrey S.K. Dahod W.S. Choi K. Brandt L.-H. Malmberg R.R. Rasmussen M.H. Scherr R.K. Flamm S. Kadam J.B. McAlpine Fusacandins A and B: Novel antifungal antibiotics of the papuolacandin class from Fusarium sambucinum , I: Identity of the producing organism, fermentation and biological activity J. Antibiot. 48 1995 608 613
80. H. Jayasuriya N.M. Koonchanok R.L. Geahlen J.L. McLaughlin C.-J. Chang Emodin, a protein tyrosine kinase inhibitor from Polygonum cuspidatum J. Nat. Prod. 55 1992 696 698
81. D.H. Jennings The Physiology of Fungal Nutrition 1995 Cambridge Univ Press, Cambridge
82. T.S. Jeong S.U. Kim B.M. Kwon K.H. Son Y.K. Kim M.U. Choi S.H. Bok GERI-BP001, a new inhibitor of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus F37 Tetrahedron Lett. 35 1994 3356 3570
83. T.-S. Jeong S.-U. Kim K.-H. Son B.-M. Kwon Y.-K. Kim M.-U. Choi S.-H. Bok GERI-BP001 compounds, new Inhibitors of acyl-CoA:cholesterol acyltransferase from Aspergillus fumigatus F37, I: Production, isolation, and physico-chemical and biological properties J. Antibiot. 48 1995 751 756
84. M.I. Johnson D.F. Hoth Present status and future prospects for HIV therapies Science 260 1993 1286 1293
85. T. Kagamizono E. Nishino K. Matsumoto A. Kawashima M. Kishimoto N. Sakai B.-M. He Z.-X. Chen T. Adachi S. Morimoto K. Hanada Bassiatin, a new platelet aggregation inhibitor produced by Beauveria bassiana K-717 J. Antibiot. 48 1995 1407 1412
86. H. Kaise M. Shinohara W. Miyazaki T. Izawa M. Nakano M. Sugawara K. Sugiura Structure of K-76, a complement inhibitor produced by Stachybotrys complementi nov. Sp. K-76 J. Chem. Soc., Chem. Commun. 1979 726 727
87. H. Kakeya I. Takahashi G. Okada K. Isono H. Osada Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, produced by a marine fungus J. Antibiot. 48 1995 733 735
88. K. Katagiri K. Sato S. Hayakawa T. Matsushima H. Minato Verticillin A, a new antibiotic from Verticillium sp J. Antibiot. 23 1970 420 422
89. Y.K. Kim H. Tomoda H. Nishida T. Sunazuka R. Obata S. Omura Pryripropenes, novel inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus , II: Structure elucidation of pyripropenes A, B, C, and D J. Antibiot. 47 1994 154 162
90. D. Kluepfel J. Bagli H. Baker M.-P. Charest A. Kudelski S.N. Segal C. Vezina Myriocin, a new antifungal antibiotic from Myriococcum albomyces J. Antibiot. 25 1972 109 115
91. H. Kobayashi R. Sunaga K. Furihata N. Morisaki S. Iwasaki Isolation and structure of an antifungal antibiotic, fusarielin A, and related compounds produced by a Fusarium sp J. Antibiot. 48 1995 42 52
92. K. Kodukula M. Arcuri J. Qian-Cutrone R.M. Hugill S.E. Lowe D.M. Pirnik Y.-Z. Shu P.B. Fernandes R. Seethala BMS-192548, a tetracyclic binding inhibitor of neuropeptide Y Receptors, from Aspergillus niger WB2346, I: Taxonomy, fermentation, isolation and biological activity J. Antibiot. 48 1995 1055 1059
93. S.B. Krasnoff D.M. Gibson G.N. Belofsky K.B. Gloer J.B. Gloer New destruxins from the entomopathogenic fungus Aschersonia sp J. Nat. Prod. 59 1996 485 489
94. P. Kulanthaivel Naturally occurring protein kinase C inhibitors Nancy Mulford Natural Products: Rapid Utilization of Sources for Drug Discovery and Development Biomedical Library Series 1995 International Business Communications Southborough, MA
95. P. Kulanthaivel Y.F. Hallock C. Boros S.M. Hamilton W.P. Janzen M. Ballas C.R. Loomis J.B. Jiang B. Katz J.R. Steiner J. Clardy Balanol: A novel and potent inhibitor of protein kinase C from the fungus Verticillium balanoides J. Am. Chem. Soc. 115 1993 6452 6453
96. M.-S. Kuo D.A. Yurek S.A. Mizsak V.P. Marshall W.F. Liggett J.I. Cialdella A.L. Laborde J.A. Shelly S.E. Thiesdell Production, isolation, and identification of dihydroepiepoformin as an IL-1 receptor antagonistic component in Penicillium patulum J. Antibiot. 48 1995 888 890
97. A.R. Lax H.S. Shepherd Tentoxin: A cyclic tetrapeptide having potential herbicidal usage H.G. Cutler Biologically Active Natural Products: Potential Use in Agriculture American Chemical Society Symposium Series 380. 1988 American Chemical Society Washington, DC 24 34
98. H.A. Lechevalier Production of the same antibiotics by members of different genera of microorganisms D. Perlman Advances in Applied Microbiology Vol. 19 1975 Academic Press New York 25 45
99. C.H. Lee H. Koshino M.C. Chung H.J. Lee Y.H. Kho MR304A, a new melanin synthesis inhibitor produced by Trichoderma harzianum J. Antibiot. 48 1995 1168 1170
100. K.H. Ling C.-K. Yang F.-T. Peng Territrems, tremorgenic mycotoxins of Aspergillus terreus Appl. Environ. Microbiol. 37 1979 355 357
101. K.H. Ling H.-H. Liou C.-M. Yang C.-K. Yang Isolation, chemical structure, acute toxicity, and some physicochemical properties of territrem C from Aspergillus terreus Appl. Environ. Microbiol. 47 1984 98 100
102. S.M. Mandala R.A. Thornton B.R. Frommer J.E. Curotto W. Rozdilsky M.B. Kurtz R.A. Giacobbe G.F. Bills M.A. Cabello I. Martin F. Pelaez G.H. Harris The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporomiella australis. Producing organism, fermentation, isolation, and biological activity J. Antibiot. 48 1995 349 356
103. V.P. Marshall S.J. McWethy J.M. Sirotti J.I. Cialdella The effect of neutral resins on the fermentation production of rubradirin J. Ind. Microbiol. 5 1990 283 287
104. J.F. Martin G. Revilla D.M. Zanca M.J. Lopez-Nieto Carbon catabolite regulation of penicillin and cephalosporin biosynthesis H. Umezawa A.L. Demain T. Hata C.R. Hutchinson Trends in Antibiotic Research: Genetics, Biosynthesis, Actions and New Substances 1982 Japan Antibiotics Research Association Tokyo
105. R. Masuma N. Tabata H. Tomoda K. Haneda Y. Iwai S. Omura Arohynapenes, new anticoccidial agents produced by Penicillium sp J. Antibiot. 47 1994 46 53
106. K. Matsumoto K. Nagashima T. Kamigauchi Y. Kawamura Y. Yasuda K. Ishi N. Uotani T. Sato H. Nakai Y. Terui J. Kikuchi Y. Ikenisi T. Yoshida T. Kato H. Itazaki Salfredins, new aldose reductase inhibitors produced by Crucibulum sp. RF-3817, 1: Fermentation, isolation and structures of salfredins J. Antibiot. 48 1995 439 446
107. K. Matsuzaki H. Ikeda R. Masuma H. Tanaka S. Omura Isochromophilones I and II, novel inhibitors against gpl20-CD4 binding produced by Penicillium multicolor FO-2338, I: Screening, taxonomy, fermentation, isolation and biological activity J. Antibiot. 48 1995 703 707
108. K. Matsuzaki H. Tanaka S. Omura Isochromophilones I and II, novel inhibitors against gp120-CD4 binding produced by Penicillium multicolor FO-2338, II: Structure elucidation J. Antibiot. 48 1995 708 713
109. F. Mayerl Q. Gao S. Huang S.E. Klohr J.A. Matson D.R. Gustavson D.M. Pirnik R.L. Berry C. Fairchild W.C. Rose Eupenifeldin, a novel cytotoxic bistropolone from Eupenicillium brefeldianum J. Antibiot. 46 1993 1082 1088
110. F. Mayerl X. Huang Q. Gao Fermentation manufacture of 1, H-cycloundeca[1,2-β:5,6-β′]bis-cyclohepta(b)pyran derivatives as antitumor agents 1994 U.S. Pat. 5284866A
111. R.F. Middletown G. Foster R.J.P. Cannell P.J. Sidebottom N.L. Taylor D. Noble M. Todd M.J. Dawson G.C. Lawrence Novel squalestatins produced by biotransformation J. Antibiot. 48 1995 311 316
112. R.F. Miller S. Huang Isolation and structure of sorrentanone: A new tetrasubstituted quinone from Penicillium chrysogenum J. Antibiot. 48 1995 520 521
113. S. Miyata N. Ohhata H. Murai Y. Masui M. Ezaki S. Takase M. Nishikawa S. Kiyota M. Okuhara M. Kohsaka WS009A and B, new endothelin receptor antagonists isolated from Streptomyces sp. no. 89009 J. Antibiot. 45 1992 1029 1040
114. U. Mocek L. Schultz T. Buchan C. Baek L. Fretto J. Nzerem L. Sehl U. Sinha Isolation and structure elucidation of five new asterriquinones from Aspergillus, Humicola and Botryotrichum species J. Antibiot. 49 1996 854 859
115. T. Morino M. Nishimoto A. Masuda S. Fujita T. Nishikiori S. Saito NK374200, a novel insecticidal agent from Talaromyces , found by physico-chemical screening J. Antibiot. 48 1995 1509 1510
116. M. Nakajima K. Itoi Y. Takamatsu S. Sato Y. Furukawa K. Furuya T. Honma J. Kadotani M. Kosaza T. Haneishi Cornexistin: A new fungal metabolite with herbicidal activity J. Antibiot. 44 1991 1065 1072
117. M. Nakamura Y. Ito K. Ogawa Y. Michisuji S.-I. Sato M. Takada M. Hayashi S. Yaginuma S. Yamamoto Stachybocins, novel endothelin receptor antagonists, produced by Stachybotrys sp. M6222, I: Taxonomy, fermentation, isolation and characterization J. Antibiot. 48 1995 1389 1395
118. Y. Nishizuka The molecular heterogeneity of protein kinase C and its implication for cellular regulation Nature 334 1988 661 665
119. S. Nokoe J. Furukawa U. Sanakawa S. Shibata Isolation, structure and synthesis of hirsutene, a precursor hydrocarbaon of coriolin biosynthesis Tetrahedron Lett. 17 1976 195 198
120. K. Nozawa S. Nakajima K. Kawai S. Udagawa Y. Horie M. Yamazaki Novel indoloditerpenes, emindoles, and related compounds from Fmericelia spp. Chem. Nat Prod., 29th Symp 1987 Sapporo Japan 637 643
121. O. Nozawa T. Okazaki N. Sakai T. Komurasaki K. Hanada S. Morimoto Z.-X. Chen B.-M. He K. Mizoue A novel bioactive δ-Lactone FD-211: Taxonomy, isolation and characterization J. Antibiot. 48 1995 113 118
122. T. Ogawa K. Ando Y. Aotani K. Shinoda T. Tanaka E. Tsukuda M. Yoshida Y. Matsuda RES-1214-1 and -2, novel non-peptide endothelin type a receptor antagonists produced by Pestalotiopsis sp J. Antibiot. 48 1995 1401 1406
123. K. Ogawa M. Nakamura M. Hayashi S. Yaginuma S. Yamamoto K. Furihata K. Shin-Ya H. Seto Stachybocins, novel endothelin receptor antagonists, produced by Stachybotrys sp. M6222, II: Structure determination of stachybocins A, B and C J. Antibiot. 48 1995 1396 1400
124. S. Omura K. Tanaka H. Ikeda R. Masuma Isochromophilones I and II, novel inhibitors against gp120-CD4 binding from Penicillium sp J. Antibiot. 46 1993 1908 1911
125. S. Omura H. Tomoda Y.K. Kim H. Nishida Pryripropenes, highly potent inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus J. Antibiot. 46 1993 1168 1169
126. S. Omura F. Kuno K. Otoguro T. Sunazuka K. Shiomi R. Masuma Y. Iwai Arisugarcin, a novel and selective inhibitor of acetylcholinesterase from Penicillium sp. FO-4259 J. Antibiot. 48 1995 745 746
127. L. Pairet S.K. Wrigley I. Chetland E.E. Reynolds M.A. Hayes J. Holloway A.M. Ainsworth W. Katzer X.-M. Cheng D.J. Hupe P. Charlton A.M. Doherty Azaphilones with endothelin receptor binding activity produced by Penicillium sclerotiorum: Taxonomy, fermentation, isolation, structure elucidation and biological activity J. Antibiot. 48 1995 913 923
128. C.J. Pearce Discovering novel bioactive compounds from fungi Nancy Mulford Natural Products: Rapid Utilization of Sources for Drug Discovery and Development Biomedical Library Series 1995 International Business Communications Southborough, MA 1.72 1.94
129. C.J. Pearce G.T. Carter J. Neitsche D.B. Borders M. Greenstein W.M. Maiese The effect of methylation inhibitors on citreamicin biosynthesis in Micromonospora citrea J. Antibiot. 44 1991 1247 1251
130. C.J. Pearce R.R. West G.T. Carter The effect of sinefungin on the biosynthesis of ganefromycin. Structures of ganefromycins delta 1–4 Tetrahedron Lett 36 1995 1809 1812
131. F. Petersen A. Fredenhagen H. Mett N.B. Lydon R. Delmendo H.-B. Jenny H.H. Peter Paeciloquinones A, B, C, D, E and F: New potent inhibitors of protein tyrosine kinases produced by Paecilomyces carneus , I: Taxonomy, fermentation, isolation and biological activity J. Antibiot. 48 1995 191 198
132. M. Pulici F. Sugawara H. Koshino J. Uzawa S. Yoshida E. Lobkovsky J. Clardy A new isodrimeninol from Pestalotiopsis sp J. Nat. Prod. 59 1996 47 48
133. J. Qian-Cutrone S. Huang L.-P. Chang D.M. Pirnik S.E. Klohr R.A. Dalterio R. Hugill S. Lowe M. Alam K. Kadow Harziphilone and fleephilone, two new HIV REV/RRE binding inhibitors produced by Trichoderma harzianum J. Antibiot. 49 1996 990 997
134. J. Qian-Cutrone S. Huang J. Trimble H. Li P.-F. Lin M. Alam S.E. Klohr K. Kadow Niruriside, a new HIV/RRE binding inhibitor from Phyllanthus niruri J. Nat. Prod. 59 1996 196 199
135. P.L. Roach I.J. Clifton V. Fulop K. Harlos G.J. Barton J. Hajdu I. Anderson C.J. Schofield J.E. Baldwin Crystal structure of isopenicillin synthase is the first from a new structural family of enzymes Nature 375 1995 700 704
136. Y. Saito K. Nakao M. Mukoyama H. Imur Increased plasma endothelin level in patients with essential hypertension JV Engl. J. Med. 322 1989 205
137. K. Sakai K. Watanabe K. Masuda M. Tsuji K. Hasumi A. Endo Isolation, characterization and biological activities of novel triprenylphenols as pancreatic cholesterol esterase inhibitors produced by Stachybotrys sp. F-1839 J. Antibiot. 48 1995 447 456
138. S. Sakamura A. Ichihara T. Yoshihara Toxins of phytopathogenic microorganisms: Structural diversity and physiological activity H.G. Cutler Biologically Active Natural Products: Potential Use in Agriculture American Chemical Society Symposium Series 380 1988 American Chemical Society Washington, DC 57 64
139. S. Sakemi T. Inagaki K. Kaneda H. Hirai E. Iwata T. Sakakibara Y. Yamauchi M. Norcia L.M. Wondrack J.A. Sutcliffe N. Kojima CJ-12,371 and CJ-12,372, two novel DNA gyrase inhibitors. Fermentation, isolation, structural elucidation and biological activities J. Antibiot. 48 1995 134 142
140. S. Sakuda Y. Otsubo Y. Yamada Structure of patulodin, a new azaphilone epoxide, produced by Penicillium urticae J. Antibiot. 48 1995 85 86
141. J.J. Sanglier G. Baumann M. Dreyfus T. Fehr R. Traber M.H. Scrierber Immunosuppressants of microbial origin Microbial Metabolites Developments in Industrial Microbiology Series 32 1990 Wm. C. Brown Publishers Dubuque, IA 1 28
142. R. Sarges Aldose reductase inhibitors: Structure–activity relationship and therapeutic potential Adv. Drug Res. 18 1989 139 175
143. S. Sasaki R. Hashimoto M. Kiuchi K. Inoue T. Ikumoto R. Hirose K. Chiba Y. Hoshino T. Okumoto T. Fujita Fungal metabolites, Part 14: Novel potent immunosuppressants, mycestericins, produced by Mycelia Sterilia J. Antibiot. 47 1994 420 433
144. G. Schlingmann R.R. West L. Milne C.J. Pearce G.T. Carter Diepoxins, novel fungal metabolites with antibiotic activity Tetrahedron Lett. 34 1993 7225 7228
145. G. Schlingmann L. Milne C.J. Pearce D.B. Borders M. Greenstein W.M. Maiese G.T. Carter Isoaltion, characterization and structure of a new allenic polyene antibiotic produced by fungus LL-07 F275 J. Antibiot. 48 1995 375 379
146. C. Shinohara K. Hasumi W. Hatsumi A. Endo Staplabin, a novel fungal triprenylphenol which stimulates the binding of plasminogen to fibrin and U937 cells J. Antibiot. 49 1996 961 966
147. K. Shiomi R. Uchida J. Inokoshi H. Tanaka Y. Iwai S. Omura Adrastins A-C, new protein farnesyltransferase inhibitors, produced by Penicillium sp. FO-3929 Tetrahedron Lett 37 1996 1265 1268
148. H. Shiozawa M. Takahashi T. Takatsu T. Kinoshita K. Tanazawa T. Hosoya K. Furuya S. Takahashi K. Furihata H. Seto Trachyspic acid, a new metabolite produced by Talaromyces trachyspermus , that inhibits tumor cell heparinase: Taxonomy of the producing strain, fermentation, isolation, structural elucidation and biological activity J. Antibiot. 48 1995 357 362
149. Y.-Z. Shu J. Qian-Cutrone S.E. Klohr S. Huang BMS-192548, a tetracyclic binding inhibitor of neuropeptide Y receptors, from Aspergillus niger WB2346, II: Physico-chemical properties and structural characterization J. Antibiot. 48 1995 1060 1065
150. P.J. Sidebottom R.M. Highcock S.J. Lane P.A. Procopiou N.S. Watson The squalestatins, novel inhibitors of squalene synthase produced by a species of Phoma , II: Structural elucidation J. Antibiot. 45 1992 648 658
151. S.B. Singh E.T. Jones M.A. Goetz G.F. Bills M. Nallin-Omstead R.G. Jenkins R.B. Lingham K.C. Silverman J.B. Gibbs Fusidienol: A novel inhibitor of ras farnesyl-protein transferase from Fusidium griseum Tetrahedron Lett. 35 1994 4693 4696
152. S.B. Singh B.A. Katz R.B. Lingham I. Martin K.C. Silverman Inhibitors of farnesyl-protein transferase 1994 U.S. Pat. 5436263-A-950725
153. D.R. Sliskovic A.D. White Therapeutic potential of ACAT inhibitors as lipid lowering and antiatherosclerotic agents Trends Pharm. Sci. 12 1991 194 199
154. M. Stadler H. Anke W.R. Arendholz F. Hansske U. Anders O. Sterner K.E. Berquist Lachnumon and lachnumol A, new metabolites with nematocidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst, I: Producing organism, fermentation, isolation and biological activities J. Antibiot. 46 1993 961 967
155. M. Stadler H. Anke O. Sterner K.E. Berquist Lachnumon and lachnumol a, new metabolites with nematocidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst, II: Structural elucidation J. Antibiot. 46 1993 968 972
156. M. Stadler O. Sterner H. Anke New biologically active compounds from the nematode-trapping fungus Arthrobotrys oligospora Fresen Z. Naturforsch. C48 1993 843 850
157. M. Stadler H. Anke O. Sterner Metabolites with nematocidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst, III: Production of novel isocoumarin derivatives, isolation, and biological activities J. Antibiot. 48 1995 261 266
158. M. Stadler H. Anke O. Sterner New metabolites with nematocidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst, IV: Structure determination of novel isocoumarin derivatives J. Antibiot. 48 1995 267 270
159. M. Stadler H. Anke O. Sterner Metabolites with nematocidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst, V: Production, isolation and biological activities of bromine-containing mycorrhizin and lachnumon derivatives and four additional new bioactive metabolites J. Antibiot. 48 1995 149 153
160. M. Stadler H. Anke R. Shan O. Stemer New metabolites with nematocidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst, VI: Structure determination of non-halogenated metabolites structurally related to mycorrhizin J. Antibiot. 48 1995 154 157
161. M. Stadler H. Anke O. Sterner New metabolites with nematocidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst, VII: Structure determination of brominated lachnumon and mycorrhizin A derivatives J. Antibiot. 48 1995 158 161
162. A. Stierle G. Strobel D. Stierle Taxol and taxane production by Taxomyces andreanae , an endophytic fungus of Pacific Yew Science 260 1993 214 216
163. M. Sugano A. Sato Y. Iijima T. Oshima K. Furuya H. Kuwano H. Hanazawa Phomactin A: A novel PAF antagonists from a marine fungus Phoma sp J. Am. Chem. Soc. 113 1991 5463 5464
164. M. Sugano A. Sato Y. Iijima K. Furuya H. Kuwano T. Hata Phomactins E, F, and G: New phomactin-group PAF antagonists from a marine fungus Phoma sp J. Antibiot. 48 1995 1188 1190
165. W.K. Summers L.V. Majovski G.M. Marsh K. Tachiki A. Kling Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type N. Engl. J. Med. 315 1986 1241 1245
166. N. Tabata H. Tomoda Y. Iwai S. Omura Arohynapene D, a new anticoccidial agent produced by Penicillium sp. FO-2295 J. Antibiot. 48 1995 83 84
167. N. Tabata H. Tomoda R. Masuma Y. Iwai S. Omura Fudecalone, a new anticoccidial agent produced by Penicillium sp. FO-2030 J. Antibiot. 48 1995 53 58
168. H. Takeshima Antiviral agents S. Omura The Search for Bioactive Compounds from Microorganisms 1992 Springer-Verlag New York
169. Y. Tanaka Fermentation processes in screening for new bioactive substances S. Omura The Search for Bioactive Compounds from Microorganisms 1992 Springer-Verlag New York
170. Y. Tanaka K. Matsuzaki C.-L. Zhong H. Yoshida T. Kawkubo R. Masuma H. Tanaka S. Omura Dechlorogeodin and its new dihydro derivatives, fungal metabolites with herbicidal activity J. Antibiot. 49 1996 1056 1059
171. M.R. TePaske Isolation and structure determination of antiinsectan metabolites from the sclerotia of aspergillus species 1991 Department of Chemistry, University of Iowa Ph.D. Thesis
172. J.S. Tkacz Glucan biosynthesis in fungi and its inhibition J.A. Sutcliffe N.H. Georgo-papadakou Emerging Targets in Antibacterial and Antifungal Chemotherapy 1992 Chapman and Hall New York 495 523
173. H. Tomoda Y.K. Kim H. Nishida R. Masuma S. Omura Pyripropenes, novel inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus , I: Production, isolation and biological properties J. Antibiot. 47 1994 148 153
174. H. Tomoda N. Tabata D.-J. Yang H. Takayanagi H. Nishida S. Omura Pyripropenes, novel ACAT inhibitors produced by Aspergillus fumigatus , III: Structure elucidation of pyripyropenes E to L J. Antibiot. 48 1995 495 503
175. H. Tomoda M. Ito N. Tabata R. Masuma Y. Yamaguchi S. Omura Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942, I: Production, isolation and biological properties J. Antibiot. 48 1995 937 941
176. H. Tomoda N. Tabata M. Ito S. Omura Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942, II: Structure elucidation of amidepsines A, B and C J. Antibiot. 48 1995 942 947
177. H. Tomoda N. Tabata D.-J. Yang H. Takayanagi S. Omura Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis , III: Production, isolation and structure elucidation of new components J. Antibiot. 48 1995 793 804
178. H. Tomoda Y. Yamaguchi N. Tabata N. Kobayashi R. Masuma T. Tanaka S. Omura Amidepsine E, an inhibitor of diacylglycerol acyltransferase produced by Humicola sp. FO-5969 J. Antibiot. 49 1996 929 931
179. W.B. Turner Fungal Metabolites 1971 Academic Press New York
180. W.B. Turner D.C. Aldridge Fungal Metabolites, II 1983 Academic Press London
181. R. Uchida K. Shiomi J. Inokoshi R. Masuma T. Kawakubo H. Tanaka Y. Iwai S. Omura Kuraosins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684, I: Producing strain, fermentation, isolation, and biological activities J. Antibiot. 49 1996 932 934
182. R. Uchida K. Shiomi T. Sunazuka J. Inokoshi A. Nishizawa T. Hirose H. Tanaka Y. Iwai S. Omura Kuraosins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684, II: Structure elucidation and total synthesis J. Antibiot. 49 1996 932 934
183. P.R. Vagelos Are prescription drug prices high? Science 252 1991 1080 1084
184. D. Van Der Pyl J. Inokoshi K. Shiomi H. Yang H. Takeshima S. Omura Inhibition of famesyl-protein transferase by gliotoxon and acetylgliotoxin J. Antibiot. 45 1992 1802 1805
185. D. Van Der Pyl P. Cans J.J. Debernard F. Herman Y. Lelievre L. Tahraoui M. Vuilhorgne J. Leboul RPR113228, a novel farnesyl-protein transferase inhibitor produced by Chrysosporium lobatum J. Antibiot. 48 1995 736 737
186. T. Watanabe N. Suzuki N. Shimamoto M. Fujino A. Imada Endothelin in myocardial infarction Nature 344 1990 114
187. H.A. Weber J.B. Gloer Preussomerins A-F: Novel antifungal metabolites from the coprophilous fungus Preussia isomera Cain J. Org. Chem. 56 1991 4355 4360
188. H.A. Weber N.C. Baenziger J.B. Gloer Structure of preussomerin A: An unusual new antifungal metabolite from the coprophilous fungus Preussia isomera J. Am. Chem. Soc. 112 1990 6718 6719
189. E.D. Weinberg Antifungal agents M.E. Wolff Burger’s Medicinal Chemistry and Drug Discovery 5th ed Therapeutic Agents 2 1996 Wiley New York 637 652
190. R.R. West J. Van Ness A.-M. Varming B. Rassing S. Biggs S. Gasper P.A. McKernan J. Piggott ZG-1494α, a novel platelet-activating factor acetyltransferase inhibitor from Penicillium rubrum: Isolation, structure elucidation and biological activity J. Antibiot. 49 1996 967 973
191. A.C. Whyte J.B. Gloer J.A. Scott D. Malloch Cercophorins A-C: Novel antifungal and cytotoxic metabolites from the coprophilus fungus Cercophora areolata J. Nat. Prod. 59 1996 765 769
192. K.A. Wood D.A. Kau S.K. Wrigley R. Beneyto D.V. Renno A.M. Ainsworth J. Penn D. Hill J. Killacky P. Depledge Novel β-methoxyacrylates of the 9-methoxystrobilurin and oudemansin classes produced by the basidiomycetes Favolaschia pustulosa J. Nat. Prod. 59 1996 646 649
193. J.C. Wu Mycophenolate mofetil: Molecular mechanism of action Perspect. Drug Discovery Des 2 1994 185 204 [This review also contains a brief history, with references, of the discovery of mycophenolic acid.]
194. S. Zapf A. Werle T. Anke D. Klostermeyer B. Steffan W. Steglich 9-Methoxystrobilurine-Bindeglieder zwischen Strobilurinen and Oudemansinen Angew. Chem. 107 1995 255 257
195. S. Zapf M. Hobfeld H. Anke R. Velten W. Steglich Darlucins A and B, new isocyanide antibiotics from Sphaerellopsis filum (Darluca filum) J. Antibiot. 48 1995 36 41
196. W. Zopf Zur Kenntnis der Infektions-Krankheiten neiderer Tiere und Pflanzen Nova Acta Leopold Carol 52 1888 314 376