Kurasoins a and b, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. II. Structure elucidation and total synthesis

Journal of Antibiotics

Volumn 49, Issue 9, 1996, Pages 886-889

  Uchida, Ryuji ^a   Shiomi, Kazuro ^a   Sunazuka, Toshiaki ^b   Inokoshi, Junji ^b   Nishizawa, A I ^b   Hirose, Tomoyasu ^b   Tanaka, Haruo ^b   Iwai, Yuzuru ^a   Omura, Satoshi ^a  

^a KITASATO INSTITUTE   (Japan)

^b KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

KURASOIN A; KURASOIN B; PROTEIN FARNESYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; DRUG SYNTHESIS; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; HYPHOMYCETES; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0029860827     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.886     Document Type: Article

References (2)

1. UCHIDA, R.; K. SHIOMI, J. INOKOSHI, R. MASUMA, T. KAWAKUBO, H. TANAKA, Y. IWAI & S. ŌMURA: Kurasoins A and B. new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. I. Producing strain, fermentation, isolation, and biological Activities. J. Antibiotics 49: 932-934, 1996
2. BASHA, A.; M. LIPTON & S. T. WEINREB: A mild, general method for conversion of esters to amides. Tetrahedron Lett. 48: 4171-4174, 1977