Entire polyprotein-ORF sequences of Japanese GBV-C/HGV isolates: Implications for new genotypes

Hepatology Research

Volumn 8, Issue 2, 1997, Pages 139-148

  Takahashi, Kazuaki ^a   Hijikata, Minako ^a   Hino, Kunihiko ^b   Mishiro, Shunji ^a  

^a Shinagawa ku   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

GBV C HGV; Genotype; Polyprotein ORF; Viral RNA genome

Indexed keywords

VIRUS RNA;

ARTICLE; CLINICAL ARTICLE; GENE INSERTION; GENOTYPE; HEPATITIS G VIRUS; HEPATITIS VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; JAPAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHYLOGENY; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; VIRUS ISOLATION;

EID: 0030867801     PISSN: 09284346     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1386-6346(97)00063-6     Document Type: Article

References (16)

1. Muerhoff AS, Simons JN, Leary TP, et al. Sequence heterogeneity within the 5′-terminal region of the hepatitis GB virus C genome and evidence for genotypes. J Hepatol 1996;25:379-84.
2. Takahashi K, Hijikata M, Aoyama K, et al. Characterization of GBV-C/HGV viral genome: comparison among different isolates for a ∼ 2 kb-sequence that covers entire E1 and most of 5′UTR and E2. Int Hep Commun 1997;6:253-63.
3. Pickerng JM, Thomas HC, Karajiannis P. Genetic diversity between hepatitis G virus isolates: analysis of nucleotide variation in the NS-3 and putative 'core' peptide genes. J Gen Virol 1997;78:53-60.
4. Linnen J, Wages J, Zhang-Keck ZY, et al. Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent. Science 1996;271:505-8.
5. Simons JN, Leary TP, Dawson GJ, et al. Isolation of novel virus-like sequences associated with human hepatitis. Nat Med 1995;1:564-9.
6. Leary TP, Muerhoff AS, Simons JN, et al. Sequence and genomic organization of GBV-C: a novel member of the Flaviviridae associated with human non-A-E hepatitis. J Med Virol 1996;48:60-7.
7. Erker JC, Simons JN, Muerhoff AS, et al. Molecular cloning and characterization of a GB virus C isolate from a patient with non-A-E-hepatitis. J Gen Virol 1996;77:2713-20.
8. Shao L, Shinzawa H, Ishikawa K, et al. Sequence of hepatitis G virus isolated from a Japanese patient with non-A-E hepatitis: amplification and cloning by long reverse transcription-PCR. Biochem Biophys Res Commun 1996;228:785-91.
9. Simons JN, Desai SM, Schultz DE, et al. Translation initiation in GB viruses A and C: evidence for internal ribosome entry and implications for genome organization. J Virol 1996;70:6126-35.
10. Okamoto H, Mishiro S. Genetic heterogeneity of hepatitis C virus. Intervirology 1994;37:68-76.
11. Enomoto N, Sakuma I, Asahina Y, et al. Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C 1b infection. N Engl J Med 1996;334:77-81.
12. Alter MJ, Gallagher M, Morris TT, et al. Acute non-A-E hepatitis in the United States and the role of hepatitis G virus infection. N Engl J Med 1997;336:741-6.
13. Alter HJ, Nakatsuji Y, Melpolder J, et al. The incidence of transfusion-associated hepatitis G virus infection and its relation to liver disease. N Engl J Med 1997;336:747-54.
14. Mizokami M, Orito E, Ohba K, et al. Genotypes and quantitation of GB virus C/hepatitis G virus. In: Abstract volume of 4th International Meeting on HCV and Related Viruses. Kyoto, 1997, 240 pp.
15. Alter HJ. The cloning and clinical implications of HGV and HGBV-C. N Engl J Med 1996;334:1536-7.
16. Mayumi M, Miyakawa Y. Hepatitis G virus - a true hepatitis virus or an accidental tourist?. N Engl J Med 1996;336:795-6.