Murine CXCR-4 is a functional coreceptor for T-cell-tropic and dual- tropic strains of human immunodeficiency virus type 1

Journal of Virology

Volumn 71, Issue 9, 1997, Pages 7097-7100

  Bieniasz, Paul D ^a   Fridell, Robert A ^a   Anthony, Kara ^a   Cullen, Bryan R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; LYMPHOCYTE COUNT; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ISOLATION; SEQUENCE HOMOLOGY; T LYMPHOCYTE; VIRUS STRAIN;

EID: 0030858633     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.9.7097-7100.1997     Document Type: Article

References (28)

1. Alkhatib, G., C. Comhadiere, C. C. Broder, Y. Feng, P. E. Kennedy, P. M. Murphy, and E. A. Berger. 1996. CC CKR5: a RANTES, MIP-lα, MIP-lβ receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272: 1955-1958.
2. Alonso, A., D. Derse, and B. M. Peterlin. 1992. Human chromosome 12 is required for optimal interactions between Tat and TAR of human immunodeficiency virus type 1 in rodent cells. J. Virol. 66:4617-4621.
3. Ashorn, P. A., E. A. Berger, and B. Moss. 1990. Human immunodeficiency virus envelope glycoprotein/CD4-mediated fusion of nonprimate cells with human cells. J. Virol. 64:2149-2156.
4. Atchison, R. E., J. Gosling, F. S. Monteclaro, C. Franci, L. Digilio, I. F. Charo, and M. A. Goldsmith, 1996. Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines. Science 274: 1924-1926.
5. Bieniasz, P. D., R. A. Fridell, I. Aramori, S. S. G. Ferguson, M. G. Caron, and B. R. Cullen. 1997. HIV-1 induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 coreceptor. EMBO J. 16:2599-2609.
6. Blair, W. S., R. A. Fridell, and B. R. Cullen. 1996. Synergistic enhancement of both initiation and elongation by acidic transcription activation domains. EMBO J. 15:1658-1665.
7. Choe, H., M. Farzan, Y. Sun, N. Sullivan, B. Rollins, P. D. Ponath, L. Wu, C. R. Mackay, G. LaRosa, W. Newman, N. Gerard, C. Gerard, and J. Sodroski. 1996. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85:1135-1148.
8. Clapham, P. R., D. Blanc, and R. A. Weiss. 1991. Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by simian immunodeficiency virus. Virology 181:703-715.
9. Cullen, B. R. 1986. Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism. Cell 46:973-982.
10. Deng, H., R. Liu, W. Ellmeier, S. Choe, D. Unutmaz, M. Burkhart, P. Di Marzio, S. Marmon, R. E. Sutton, C. M. Hill, C. B. Davis, S. C. Peiper, T. J. Schall, D. R. Littman, and N. R. Landau. 1996. Identification of a major co-receptor for primary isolates of HIV-1 Nature 381:661-666.
11. Dittmar, M. T., A. McKnight, G. Simmons, P. R. Clapham, and R. A. Weiss. 1997. HIV-1 tropism and coreceptor use. Nature 385:495-496.
12. Doranz, B. J., J. Rucker, Y. Yi, R. J. Smyth, M. Samson, S. C. Peiper, M. Parmentier, R. G. Collman, and R. W. Doms. 1996. A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 85:1149-1158.
13. + cells is mediated by the chemokine receptor CC-CKR-5. Nature 381:667-673.
14. Feng, Y., C. C Broder, P. E. Kennedy, and E. A. Berger. 1996. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein- coupled receptor. Science 272:872-877.
15. Heesen, M., M. A. Berman, J. D. Benson, C. Gerard, and M. E. Dorf. 1996. Cloning of the mouse fusin gene, homologue to a human HIV-1 cofactor. J. Immunol. 157:5455-5460.
16. Loetscher, M., T. Geiser, T. O'Reilly, R. Zwahlen, M. Baggiolini, and B. Moser. 1994. Cloning of a human seven-transmembrane domain receptor LESTR, that is highly expressed in leukocytes. J. Biol. Chem. 269:232-237.
17. Lorès, P., V. Boucher, C. Mackay, M. Pla, H. Von Boehmer, J. Jami, F. Barré-Sinoussi, and J.-C. Weill. 1992. Expression of human CD4 in transgenic mice does not confer sensitivity to human immunodeficiency virus infection. AIDS Res. Hum. Retroviruses 8:2063-2071.
18. Maddon, P. J., A. G. Daigleish, J. S. McDougal, P. R. Clapham, R. A. Weiss, and R. Axel. 1986. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 47:333-348.
19. Madore, S. J., and B. R. Cullen. 1993. Genetic analysis of the cofactor requirement tor human immunodeficiency virus type 1 Tat function. J. Virol. 67:3703-3711.
20. Moore, J. P., A. Trkola, and T. Dragic. Coreceptors for HIV-1 entry. Curr. Opin. Immunol., in press.
21. Nagasawa, T., T. Nakajima, K. Tachibana, IL lizasa, C. C. Bleul, O. Yoshie, K. Matsushima, N. Yoshida, T. A. Springer, and T. Kishimoto. 1996. Molecular cloning and characterization of a murine prc-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc. Natl. Acad. Sci. USA 93:14726-14729.
22. + cells expressing the rat homolog of CXCR-4 (fusin). J. Virol. 71:3259-3262.
23. Reppert, S. M., D. R. Weaver, J. H. Stehle, S. A. Rivkees, S. Grabbe, and R. D. Granstein. 1992. Molecular cloning of a G protein-coupled receptor that is highly expressed in lymphocytes and proliferative areas of developing brain. Mol. Cell. Neurosci. 3:206-214.
24. Rucker, J., M. Samson, B. J. Duranz, F. Libert, J. F. Berson, Y. Yi, R. J. Smyth, R. G. Collman, C. C. Broder, G. Vassart, R. W. Doms, and M. Parmentier. 1996. Regions in β-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity. Cell 87:437-446.
25. Simmons, G., D. Wilkinson, J. D. Reeves, M. T. Dittmar, S. Beddows, J. Weber, G. Carnegie, U. Desselberger, P. W. Gray, R. A. Weiss, and P. R. Clapham. 1996. Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry. J. Virol. 70:8355-8360.
26. Simon, J. H. M., G. A. Schockmel, P. Illei, and W. James. 1994. A rodent cell line permissive for entry and reverse transcription of human immunodeficiency virus type 1 has a pre-integration block to productive infection. J. Gen. Virol. 75:2615-2623.
27. Wong, M.-L., W. W. Xin, and R. S. Duman. 1996. Rat LCR1: cloning and cellular distribution of a putative chemokine receptor in the brain. Mol Psychiatry 1:133-140.
28. Zhang, L., Y. Huang, T. He, Y. Cao, and D. D. Ho. 1996. HIV-1 subtype and second-receptor use. Nature 383:768.