An antagonist for the leukemia inhibitory factor receptor inhibits leukemia inhibitory factor, cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M

Journal of Biological Chemistry

Volumn 272, Issue 43, 1997, Pages 26947-26952

  Vernallis, Ann B ^a   Hudson, Keith R ^a   Heath, John K ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; LEUKEMIA INHIBITORY FACTOR; ONCOSTATIN M;

ANIMAL CELL; ARTICLE; GENE MUTATION; HUMAN; HUMAN CELL; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

CELL DIVISION; CELL LINE; CILIARY NEUROTROPHIC FACTOR; CLONING, MOLECULAR; CYTOKINES; ESCHERICHIA COLI; GROWTH INHIBITORS; HUMANS; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT; LYMPHOKINES; MUTAGENESIS, SITE-DIRECTED; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; ONCOSTATIN M; PEPTIDES; RECEPTORS, CYTOKINE; RECEPTORS, OSM-LIF; RECOMBINANT PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0030856734     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.43.26947     Document Type: Article

References (76)

1. Kishimoto, T., Akira, S., Narazaki, M., and Taga, T. (1995) Blood 86, 1243-1254
2. Baumann, H., Symes, A. J., Comeau, M. R., Morella, K. K., Wang, Y., Friend, D., Ziegler, S. F., Fink, J. S., and Gearing, D. P. (1994) Mol. Cell. Biol. 14, 138-146
3. Baumann, H., Ziegler, S. F., Mosley, B., Morella, K. K., Pajovic, S., and Gearing, D. P. (1993) J. Biol. Chem. 268, 8414-8417
4. Gearing, D. P., Thut, C. J., VandenBos, T., Gimpel, S. D., Delaney, P. B., King, J., Price, V., Cosman, D., and Beckmann, M. P. (1991) EMBO J. 10, 2839-2848
5. Gearing, D. P., VandenBos, T., Beckmann, M. P., Thut, C. J., Comeau, M. R., Mosley, B., and Ziegler, S. F. (1992) CIBA Found. Symp. 167, 245-259
6. Gearing, D. P., Ziegler, S. F., Comeau, M. R., Friend, D., Thoma, B., Cosman, D., Park, L., and Mosley, B. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 1119-1123
7. Pennica, D., Shaw, K. J., Swanson, T. A., Moore, M. W., Shelton, D. L., Zioneheck, K. A., Rosenthal, A., Taga, T., Paoni, N. F., and Wood, W. I. (1995) J. Biol. Chem. 270, 10915-10922
8. Davis, S., Aldrich, T. H., Stahl, N., Pan, L., Taga, T., Kishimoto, T., Ip, N. Y., and Yancopoulos, G. D. (1993) Science 260, 1805-1808
9. Ip, N. Y., McClain, J., Barrezueta, N. X., Aldrich, T. H., Pan, L., Li, Y., Wiegand, S. J., Friedman, B., Davis, S., and Yancopoulos, G. D. (1993) Neuron 10, 89-102
10. Thoma, B., Bird, T. A., Friend, D. J., Gearing, D. P., and Dower, S. K. (1994) J. Biol. Chem. 269, 6215-6222
11. Gearing, D. P., and Bruce, A. G. (1992) New Biol. 4, 61-65
12. Lutticken, C., Wegenka, U. M., Yuan, J., Buschmann, J., Schindler, C., Ziemiecki, A., Harpur, A. G., Wilks, A. F., Yasukawa, K., Taga, T., Kishimoto, T., Barbieri, G., Pellegrini, S., Sendter, M., Heinrich, P. C., and Horn, F. (1994) Science 263, 89-92
13. Stahl, N., Boulton, T. G., Farruggella, T., Ip, N. Y., Davis, S., Witthuhn, B. A., Quelle, F. W., Silvennoinen, O., Barbieri, G., Pellegrini, S., Inle, J. N., and Yancopoulos, G. D. (1994) Science 263, 92-95
14. Boulton, T. G., Stahl, N., and Yancopoulos, G. D. (1994) J. Biol. Chem. 269, 11648-11655
15. Boulton, T. G., Zhong, Z., Wen, Z., Darnell, J. E., Jr., Stahl, N., and Yancopoulos, G. D. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6915-6919
16. Akira, S., Nishio, Y., Inoue, M., Wang, X.-J., Wei, S., Matsusaka, T., Yoshida, K., Sudo, T., Naruto, M., and Kishimoto, T. (1994) Cell 77, 63-71
17. Wegenka, U. M., Lutticken, C., Buschmann, J., Yuan, J., Lottspeich, F., Muller-Esterl, W., Schindler, C., Roeb, E., Heinrich, P. C., and Horn, F. (1994) Mol. Cell. Biol. 14, 3186-3196
18. Ihle, J. N. (1995) Nature 377, 591-594
19. Ihle, J. N. (1996) Cell 84, 331-334
20. Mosley, B., De Imus, C., Friend, D., Boiani, N., Thoma, B., Park, L. S., and Cosman, D. (1996) J. Biol. Chem. 271, 32635-32643
21. Owczarek, C. M., Layton, M. J., Robb, L. G., Nicola, N. A., and Begley, C. G. (1996) J. Biol. Chem. 271, 5495-5504
22. Taga, T. (1996) J. Neurochem. 67, 1-10
23. DeChiara, T. M., Vejsada, R., Poueymirou, W. T., Acheson, A., Suri, C., Conover, J. C., Friedman, B., McClain, J., Pan, L., Stahl, N., Ip, N. Y., Kato, A., and Yancopoulos, G. D. (1995) Cell 83, 313-322
24. Li, M., Sendtner, M., and Smith, A. (1995) Nature 378, 724-727
25. Ware, C. B., Horowitz, M. C., Renshaw, B. R., Hunt, J. S., Liggitt, D., Koblar, S. A., Gliniak, B. C., McKenna, H. J., Papayannopoulou, T., Thoma, B., Cheng, L., Donovan, P. J., Peschon, J. J., Bartlett, P. F., Willis, C. R., Wright, B. D., Carpenter, M. K., Davison, B. L., and Gearing, D. P. (1995) Development 121, 1283-1299
26. Crichton, M. B., Nichols, J. E., Zhao, Y., Bulun, S. E., and Simpson, E. R. (1996) Mol. Cell. Endocrinol. 118, 215-220
27. Lotz, M., Moats, T., and Villiger, P. M. (1992) J. Clin. Invest. 90, 888-896
28. Brown, M. A., Metcalf, D., and Gough, N. M. (1994) Cytokine 6, 300-309
29. Ulich, T. R., Fann, M.-J., Patterson, P. H., Williams, J. H., Samal, B., Del Castillo, J., Yin, S., Guo, K., and Remick, D. G. (1994) Am. J. Physiol. 267, L442-L446
30. Lecron, J. C., Roblot, P., Chevalier, S., Morel, F., Alderman, E., Gombert, J., and Gascan, H. (1993) Clin. Exp. Immunol. 92, 23-26
31. Omori, N., Evarts, R. P., Omori, M., Hu, Z., Marsden, E. R., and Thorgeirsson, S. S. (1996) Lab. Invest. 75, 15-24
32. Kurek, J. B., Nouri, S., Kannourakis, G., Murphy, M., and Austin, L. (1996) Muscle Nerve 19, 1291-1301
33. Ip, N. Y., Wiegand, S. J., Morse, J., and Rudge, J. S. (1993) Eur. J. Neurosci. 5, 25-33
34. Rudge, J. S., Li, Y., Pasnikowski, E. M., Mattsson, K., Pan, L., Yancopoulos, G. D., Wiegand, S. J., Lindsay, R. M., and Ip, N. Y. (1994) Eur. J. Neurosci. 6, 693-705
35. Sun, Y., Rao, M. S., Zigmond, R. E., and Landis, S. C. (1994) J. Neurobiol. 25, 415-430
36. Sun Y., and Zigmond, R. E. (1996) Eur. J. Neurosci. 8, 2213-2220
37. Sun, Y., and Zigmond, R. E. (1996) J. Neurochem. 67, 1751-1760
38. Davis, S., Aldrich, T. H., Ip, N. Y., Stahl, N., Scherer, S., Farruggella, T., DiStefano, P. S., Curtis, R., Panayotatos, N., Gascan, H., Chevalier, S., and Yancopoulos, G. D. (1993) Science 259, 1736-1739
39. Banner, L. R., and Patterson, P. H. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7109-7113
40. Thompson, S. W. N., Vernallis, A. B., Heath, J. K., and Priestley, J. V. (1997) Eur. J. Neurosci. 9, 1244-1251
41. Zhang, X.-G., Gu, J. J., Lu, Z. Y., Yasukawa, K., Yancopoulos, G. D., Turner, K., Shoyab, M., Taga, T., Kishimoto, T., Bataille, R., and Klein, B. (1994) J. Exp. Med. 179, 1337-1342
42. Hudson, K. R., Vernallis, A. B., and Heath, J. K. (1996) J. Biol. Chem. 271, 11971-11978
43. Layton, M. J., Lock, P., Metcalf, D., and Nicola, N. A. (1994) J. Biol. Chem. 269, 17048-17055
44. Gearing, D. P., Comeau, M. R., Friend, D. J., Gimpel, S. D., Thut, C. J., McGourty, J., Brasher, K. K., King, J. A., Gillis, S., Mosley, B., Ziegler, S. F., and Cosman, D. (1992) Science 255, 1434-1437
45. Robinson, R. C., Grey, L. M., Staunton, D., Vankelecom, H., Vernallis, A. B., Moreau, J.-F., Stuart, D. I., Heath, J. K., and Jones, E. Y. (1994) Cell 77, 1-20
46. DuBridge, R. B., Tang, P., Hsia, H. C., Leong, P. M., Miller, J. H., and Calos, M. P. (1987) Mol. Cell. Biol. 7, 379-387
47. Smith, D. B., and Johnson, K. S. (1988) Gene (Amst.) 67, 31-40
48. Cordingley, M. G., Callahan, P. L., Sardana, V. V., Garsky, V. M., and Colonno, R. J. (1990) J. Biol. Chem. 265, 9062-9065
49. Long, A. C., Orr, D. C., Cameron, J. M., Dunn, B. M., and Kay, J. (1989) FEBS Lett. 258, 75-78
50. Saggio, I., Paonessa, G., Gloaguen, I., Graziani, R., De Serio, A., and Laufer, R. (1994) Anal. Biochem. 221, 387-391
51. Harlow, E., and Lane, D. (1988) Antibodies: A Laboratory Manual, pp. 522-523, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
52. Mosmann, T. (1983) J. Immunol. Methods 65, 55-63
53. Piquet-Pellorce, C., Grey, L., Mereau, A., and Heath, J. K. (1994) Exp. Cell Res. 213, 340-347
54. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, pp. 16.33-16.34, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
55. Tsukada, T., Fink, J. S., Mandel, G., and Goodman, R. H. (1987) J. Biol. Chem. 262, 8743-8747
56. Johnson, J. A., and Nathanson, N. M. (1994) J. Biol. Chem. 269, 18856-18863
57. Yang, Y.-C., Ciarletta, A. B., Temple, P. A., Chung, M. P., Kovacic, S., Witek-Giannotti, J. S., Leary, A. C., Kriz, R., Donahue, R. E., Wong, G. G., and Clark, S. C. (1986) Cell 47, 3-10
58. Bellido, T., Stahl, N., Farruggella, T. J., Borba, V., Yancopoulos, G. D., and Manolagas, S. C. (1996) J. Clin. Invest. 97, 431-437
59. Rao, M. S., Symes, A., Malik, N., Shoyab, M., Fink, J. S., and Landis, S. C. (1992) Neuroreport 3, 865-868
60. Symes, A., Lewis, S., Corpus, L., Rajan, P., Hyman, S. E., and Fink, J. S. (1994) Mol. Endocrinol. 8, 1750-1763
61. O'Dorisio, M. S., Fleshman, D. J., Qualman, S. J., and O'Dorisio, T. M. (1992) Regul. Pept. 37, 213-226
62. Fuh, G., Cunningham, B. C., Fukunaga, R., Nagata, S., Goeddel, D. V., and Wells, J. A. (1992) Science 256, 1677-1680
63. Tony, H. P., Shen, B. J., Reusch, P., and Sebald, W. (1994) Eur. J. Biochem. 225, 659-665
64. Hercus, T. R., Bagley, C. J., Cambareri, B., Dottore, M., Woodcock, J. M., Vadas, M. A., Shannon, M. F., and Lopez, A. F. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5838-5842
65. Ehlers, M., de Hon, F. D., Bos, H. K., Horsten, U., Kurapkat, G., van De Leur, H. S., Grotzinger, J., Wollmer, A., Brakenhoff, J. P., and Rose-John, S. (1995) J. Biol. Chem. 270, 8158-8163
66. Sporeno, E., Savino, R., Ciapponi, L., Paonessa, G., Cabibbo, A., Lahm, A., Pulkki, K., Sun, R.-X., Toniatti, C., Klein, B., and Ciliberto, G. (1996) Blood 87, 4510-4519
67. Di Marco, A., Gloaguen, I., Graziani, R., Paonessa, G., Saggio, I., Hudson, K. R., and Laufer, R. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 9247-9252
68. de Hon, F. D., Ehlers, M., Rose-John, S., Ebeling, S. B., Bos, H. K., Aarden, L. A., and Brakenhoff, J. P. (1994) J. Exp. Med. 180, 2395-2400
69. Savino, R., Ciapponi, L., Lahm, A., Demartis, A., Cabibbo, A., Toniatti, C., Delmastro, P., Altamura, S., and Ciliberto, G. (1994) EMBO J. 13, 5863-5870
70. Grunewald, S. M., Kunzmann, S., Schnarr, B., Ezernieks, J., Sebald, W., and Duschl, A. (1997) J. Biol. Chem. 272, 1480-1483
71. Stahl, N., Farruggella, T. J., Boulton, T. G., Zhong, Z., Darnell, J. E., Jr., and Yancopoulos, G. D. (1995) Science 267, 1349-1353
72. Oliviero, S., and Cortese, R. (1989) EMBO J. 8, 1145-1151
73. Rajan, P., Symes, A. J., and Fink, J. S. (1996) J. Neurosci. Res. 43, 403-411
74. Neophytou, C., Vernallis, A. B., Smith, A., and Raff, M. C. (1997) Development 124, 2345-2354
75. Aversa, G., Punnonen, J., Cocks, B. G., de Waal Malefyt, R., Vega, F., Jr., Zurawski, S. M., Zurawski, G., and de Vries, J. E. (1993) J. Exp. Med. 178, 2213-2218
76. Zurawski, S. M., Vega, F., Jr., Huyghe, B., and Zurawski, G. (1993) EMBO J. 12, 2663-2670