Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 14, 1997, Pages 1897-1902

  Rastelli, Giulio ^a   Vianello, Paola ^b   Barlocco, Daniela ^b   Costantino, Luca ^a   Del Corso, Antonella ^c   Mura, Umberto ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b Istituto Chimico Farmaceutico   (Italy)

^c Dipto di Fisiologia e Biochimica   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR;

AFFINITY LABELING; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DRUG DESIGN; ENZYME ACTIVE SITE; ENZYME BINDING; METHODOLOGY; MOLECULAR MODEL; THEORY;

EID: 0030854601     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00321-1     Document Type: Article

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