Kinetic and spectroscopic evidence for active site inhibition of human aldose reductase

Biochemistry

Volumn 35, Issue 34, 1996, Pages 11196-11202

  Nakano, Takayuki ^a,b   Mark Petrash, J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GPC Biotech Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; RECOMBINANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SORBINIL; ZOPOLRESTAT;

ARTICLE; BINDING SITE; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME BINDING; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; ENZYME ISOLATION; ENZYME SUBSTRATE COMPLEX; FLUOROMETRY; HUMAN; INHIBITION KINETICS; PRIORITY JOURNAL; THERMODYNAMICS;

ALDEHYDE REDUCTASE; BENZOTHIAZOLES; BINDING SITES; ENZYME INHIBITORS; GLYCERALDEHYDE; HUMANS; HYDANTOINS; IMIDAZOLES; IMIDAZOLIDINES; KINETICS; PHTHALAZINES; PROTEIN BINDING; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS; THIAZOLES;

EID: 0029756487     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9608121     Document Type: Article

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