7-oxa[2.2.1]bicycloheptane-2,3-dicarboxylic acid derivates as phosphatase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 19, 1997, Pages 2513-2518

  Enz, Albert ^a   Zenke, Gerhard ^a   Pombo Villar, Esteban ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CANTHARIDIN; ENZYME INHIBITOR; INTERLEUKIN 2; NORCANTHARIDIN; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A;

ARTICLE; DEPHOSPHORYLATION; DRUG ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOMODULATION; LEUKEMIA CELL LINE; LYMPHOCYTE;

EID: 0030825109     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)10005-1     Document Type: Article

References (35)

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30. PP1: Egloff, M.-P., Cohen, P.T.W., Reinemer, P., Barford, D., J. Mol. Biol., 1995, 254, 942; Goldberg, J., Huang, H.-B., Kuon, Y., Greengard, P., Nairn, A.C., Kuriyan, J., Nature, 1995, 376, 745; PP2A: Skidmore, M.O., Sawaya, M.R., Parkin, S., Rupp, B., Hakon, H., Everse, S.J., Walter, G., Protein Sci, 1996, 5, 1198; PP2B: Griffith, J.P., Kim, J.L., Kim, E.E., Sintchak, M.D., Thomson, J.A., Fitzgibbon, M.J., Fleming, M.A., Caron, P.A., Hsiao, K., Navia, M.A., Cell, 1995, 82, 507 Kissinger, C.R., Parge, H.E., Knighton, D.R., Lewis, C.T., Pelletier, L.A., Tempczyk, A., Kalish, V.J., Tucker, K.D., Showalter, R.E., Moomaw, E.W., Gastinel, L.N., Habuka, N., Chen, X., Maldonado, F., Barker, J.E., Bacquet, R., Villafranca, E., Nature, 1995, 375, 641.
31. PP1: Egloff, M.-P., Cohen, P.T.W., Reinemer, P., Barford, D., J. Mol. Biol., 1995, 254, 942; Goldberg, J., Huang, H.-B., Kuon, Y., Greengard, P., Nairn, A.C., Kuriyan, J., Nature, 1995, 376, 745; PP2A: Skidmore, M.O., Sawaya, M.R., Parkin, S., Rupp, B., Hakon, H., Everse, S.J., Walter, G., Protein Sci, 1996, 5, 1198; PP2B: Griffith, J.P., Kim, J.L., Kim, E.E., Sintchak, M.D., Thomson, J.A., Fitzgibbon, M.J., Fleming, M.A., Caron, P.A., Hsiao, K., Navia, M.A., Cell, 1995, 82, 507 Kissinger, C.R., Parge, H.E., Knighton, D.R., Lewis, C.T., Pelletier, L.A., Tempczyk, A., Kalish, V.J., Tucker, K.D., Showalter, R.E., Moomaw, E.W., Gastinel, L.N., Habuka, N., Chen, X., Maldonado, F., Barker, J.E., Bacquet, R., Villafranca, E., Nature, 1995, 375, 641.
32. PP1: Egloff, M.-P., Cohen, P.T.W., Reinemer, P., Barford, D., J. Mol. Biol., 1995, 254, 942; Goldberg, J., Huang, H.-B., Kuon, Y., Greengard, P., Nairn, A.C., Kuriyan, J., Nature, 1995, 376, 745; PP2A: Skidmore, M.O., Sawaya, M.R., Parkin, S., Rupp, B., Hakon, H., Everse, S.J., Walter, G., Protein Sci, 1996, 5, 1198; PP2B: Griffith, J.P., Kim, J.L., Kim, E.E., Sintchak, M.D., Thomson, J.A., Fitzgibbon, M.J., Fleming, M.A., Caron, P.A., Hsiao, K., Navia, M.A., Cell, 1995, 82, 507 Kissinger, C.R., Parge, H.E., Knighton, D.R., Lewis, C.T., Pelletier, L.A., Tempczyk, A., Kalish, V.J., Tucker, K.D., Showalter, R.E., Moomaw, E.W., Gastinel, L.N., Habuka, N., Chen, X., Maldonado, F., Barker, J.E., Bacquet, R., Villafranca, E., Nature, 1995, 375, 641.
33. PP1: Egloff, M.-P., Cohen, P.T.W., Reinemer, P., Barford, D., J. Mol. Biol., 1995, 254, 942; Goldberg, J., Huang, H.-B., Kuon, Y., Greengard, P., Nairn, A.C., Kuriyan, J., Nature, 1995, 376, 745; PP2A: Skidmore, M.O., Sawaya, M.R., Parkin, S., Rupp, B., Hakon, H., Everse, S.J., Walter, G., Protein Sci, 1996, 5, 1198; PP2B: Griffith, J.P., Kim, J.L., Kim, E.E., Sintchak, M.D., Thomson, J.A., Fitzgibbon, M.J., Fleming, M.A., Caron, P.A., Hsiao, K., Navia, M.A., Cell, 1995, 82, 507 Kissinger, C.R., Parge, H.E., Knighton, D.R., Lewis, C.T., Pelletier, L.A., Tempczyk, A., Kalish, V.J., Tucker, K.D., Showalter, R.E., Moomaw, E.W., Gastinel, L.N., Habuka, N., Chen, X., Maldonado, F., Barker, J.E., Bacquet, R., Villafranca, E., Nature, 1995, 375, 641.
34. PP1: Egloff, M.-P., Cohen, P.T.W., Reinemer, P., Barford, D., J. Mol. Biol., 1995, 254, 942; Goldberg, J., Huang, H.-B., Kuon, Y., Greengard, P., Nairn, A.C., Kuriyan, J., Nature, 1995, 376, 745; PP2A: Skidmore, M.O., Sawaya, M.R., Parkin, S., Rupp, B., Hakon, H., Everse, S.J., Walter, G., Protein Sci, 1996, 5, 1198; PP2B: Griffith, J.P., Kim, J.L., Kim, E.E., Sintchak, M.D., Thomson, J.A., Fitzgibbon, M.J., Fleming, M.A., Caron, P.A., Hsiao, K., Navia, M.A., Cell, 1995, 82, 507 Kissinger, C.R., Parge, H.E., Knighton, D.R., Lewis, C.T., Pelletier, L.A., Tempczyk, A., Kalish, V.J., Tucker, K.D., Showalter, R.E., Moomaw, E.W., Gastinel, L.N., Habuka, N., Chen, X., Maldonado, F., Barker, J.E., Bacquet, R., Villafranca, E., Nature, 1995, 375, 641.
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