Human herpesvirus-8

Current Opinion in Oncology

Volumn 9, Issue 5, 1997, Pages 440-449

  Gillison, Maura L ^a   Ambinder, Richard F ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOFOLLICULAR LYMPH NODE HYPERPLASIA; CARCINOGENESIS; CELL CYCLE; DISEASE ASSOCIATION; HERPES VIRUS; HUMAN; HUMAN HERPESVIRUS 8; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; KAPOSI SARCOMA; LYMPHOMA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; VIRUS GENOME; VIRUS INFECTION;

EID: 0030817697     PISSN: 10408746     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001622-199709050-00008     Document Type: Review

References (115)

1. Giraldo G, Beth P, Coeur PLVC, Dhru DS: Kaposi's sarcoma: A new model in the search for viruses associated with human malignancies. J Natl Cancer Inst 1972, 49:1495-1503.
2. Geraldo G, Beth E, Haguenau F: Herpes-type virus particles in tissue culture of Kaposi's sarcoma from different geographic regions. J Natl Cancer Inst 1972, 49:1509-1513.
3. Jahan N, Razzaque A, Greenspan J, Conant MA, Josephs SF, Nakamura S, Rosenthal LJ: Analysis of human KS biopsies and cloned cell lines for cytomegalovirus, HIV-1, and other selected DNA virus sequences. Aids Res Hum Retroviruses 1989, 5:225-227.
4. Ambinder RF, Newman C, Hayward GS, Biggar R, Melbye M, Kestens L, Marck EV, Piot P, Gigase P, Wright PB, et al.: Lack of association of cytomegalovirus with endemic African Kaposi's sarcoma. J Infect Dis 1987, 156:193-197.
5. Myers BD, Kessler E, Levi J, Pick A, Rosenfeld JB, Tikvah P: Kaposi sarcoma in kidney transplant recipients. Arch Intern Med 1974, 133:307-311.
6. Jacobson LP, Armenian HK: An integrated approach to the epidemiology of Kaposi's sarcoma. Curr Opin Oncol 1995, 7:450-455.
7. Beral V, Peterman TA, Berkelman RL, Jaffe HW: Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection? Lancet 1990, 335:123-128.
8. Friedman-Kein AE, Saltzman BR, Cao Y, Nestor MS, Mirabile M, Li JJ, Peterman TA: Kaposi's sarcoma in HIV-negative homosexual men. Lancet 1990, 335:168-169.
9. Lisitsyn N, Lisitsyn N, Wigler M: Cloning the differences between two complex genomes. Science 1993, 259:946-951.
10. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS: Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994, 266:1865-1869.
11. Moore PS, Chang Y: Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and those without HIV infection. N Engl J Med 1995, 332:1181-1185.
12. Ambroziak JA, Blackbourn DJ, Herndier BH, Glogau RG, Gullett JH, McDonald AR, Lennette ET, Levy JL: Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients. Science 1995, 268:582-583.
13. Huang YQ, Li JJ, Kaplan MH, Poiesz B, Katabira E, Zhang WC, Feiner D, Friedman-Kein AE: Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcoma. Lancet 1995, 345:759-761.
14. Dupin N, Grandadam M, Calvez V, Gorin I, Aubin JT, Havard S, Lamy F, Leibowitch M, Huraux JM, Escande JP, et al.: Herpevirus-like DNA sequences in patients with Mediterranean Kaposi's sarcoma. Lancet 1995, 345:761-762.
15. Chang Y, Ziegler J, Wabinga H, Katangole-Mbidde E, Boshoff C, Schulz T, Whitby D, Maddelena D, Jaffe HW, Weiss RA, et al.: Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Arch Intern Med 1996, 156:202-204.
16. Marchioli CC, Love JL, Abbott LZ, Huang YQ, Remick SC, Surtento-Reodica N, Hutchison RE, Mildvan D, Friedman-Kien AE, Poiesz BJ: Prevalence of human herpesvirus 8 DNA sequences in several patient populations. J Clin Microbiol 1996, 34:2635-2638.
17. Chuck S, Grant RM, Katongole-Mbidde E, Conant M, Ganem D: Frequent presence of a novel herpesvirus genome in lesions of human immunodeficiency virus-negative Kaposi's sarcoma. J Infect Dis 1996, 173:248-251.
18. Dictor M, Rambech E, Way D, Witte M, Bendsoe N: Human herpesvirus B (Kaposi's sarcoma associated herpesvirus) DNA in Kaposi's sarcoma lesions, AIDS Kaposi's sarcoma cell lines, endothelial Kaposi's sarcoma simulators, and the skin of immunosuppressed patients. Am J Pathol 1996, 148:2009-2016.
19. O'Neill E, Henson TH, Ghorbadi AJ, Land MA, Webber BL, Garcia JV: Herpes virus-like sequences are specifically found in Kaposi's sarcoma lesions. J Clin Pathol 1996, 49:306-308.
20. Su I-J, Hsu I-S, Chang Y-C, Wang I-W: Herpesvirus-like DNA sequences in Kaposi's sarcoma from AIDS and non-AIDS patients in Taiwan. Lancet 1995, 345:722-723.
21. Noel JC, Hermans P, Andre J, Fayt I, Simonart T, Verhest A, Haot J, Burny A: Herpesvirus-like DNA sequences and Kaposi's sarcoma. Relationship with epidemiology, clinical spectrum, and histologic features. Cancer 1996, 77:2132-2136.
22. Noel JC: Kaposi's sarcoma and KSHV. Lancet 1995, 346:1359.
23. Luppi M, Barozzi P, Maiorana A, Collina G, Ferrari MG, Marasca R, Morselli M, Rossi E, Ceccherini-Nelli L, Torelli G: Frequency and distribution of herpesvirus-like DNA sequences (KSHV) in different stages of classic Kaposi's sarcoma and in normal tissues from an Italian population. Int J Cancer 1996, 66:427-431.
24. Staskus KA, Zhong W, Gebhard K, Herndier B, Wang E, Renne R, Beneke J, Pudny J, Anderson DJ, Ganem D, et al.: Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells. J Virol 1997, 71:715-719.
25. Boshoff C, Schulz TF, Kennedy MM, Graham AK, Fisher C, Thomas A, McGee JO, Weiss RA, O'Leary JJ: Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells. Nat Med 1995, 1:1274-1278.
26. Sirianni MC, Uccini S, Angeloni A, Faggioni A, Cottoni F, Ensoli B: Circulating spindle cells: correlation with human herpesvirus-8 (HHV-8) infection and Kaposi's sarcoma. Lancet 1997, 349:255.
27. Uccini S, Sirianni MC, Vicenzi L, Topino S, Stoppacciaro A, Lesnoni La Parola I, Capuano M, Masini C, Cerimele D, Cella M, et al.: Kaposi's sarcoma cells express the macrophage-associated antigen mannose receptor and develop in peripheral blood cultures of Kaposi's sarcoma patients. Am J Pathol 1997, 150:929-938.
28. Browning PJ, Sechler JMG, Kaplan M, Washington RH, Gendelman R, Yarchoan R, Ensoli B, Gallo RC: Identification and culture of Kaposi's sarcoma-like spindle cells from the peripheral blood of human immunodeficiency virus-1 -infected individuals and normal controls. Blood 1994, 84:2711-2720.
29. Whitby D, Howard MR, Tenant-Flowers M, Brink NS, Copas A, Boshoff C, Hatzioannou T, Suggett FEA, Aldam DM, Denton AS, et al.: Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma. Lancet 1995, 346:799-802. This is the first article demonstrating that KSHV infection precedes development of KS.
30. De Milito, A, Catucci M, Venturi G, Romano L, Valensin PE, Zazzi M, Almi P: Human immunodeficiency virus-1 infection, homosexuality, and Kaposi-associated herpes-like DNA in peripheral blood mononuclear cells. Blood 1996, 87:3521-3522.
31. Moore PS, Kingsley LA, Holmberg SD, Spira T, Gupta P, Hoover DR, Parry JP, Conley LJ, Jaffe HW, Chang Y: Kaposi's sarcoma-associated herpesvirus infection prior to onset of Kaposi's sarcoma. AIDS 1996, 10:175-180.
32. Brambilla L, Boneschi V, Berti E, Corbellino M, Parravicini C: HHV8 cell-associated viraemia and clinical presentation of Mediterranean Kaposi's sarcoma. Lancet 1996, 347:1338.
33. Lennette ET, Blackbourn DJ, Levy JA: Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients. Lancet 1996, 348:858-861.
34. Gao SJ, Kingsley L, Li M, Zheng W, Parravicini C, Ziegler J, Newton R, Rinaldo CR, Saah A, Phair J, et al.: KSHV antibodies among Americans, Italians, and Ugandans with and without Kaposi's sarcoma. Nat Med 1996, 2:925-928.
35. Kedes DH, Operskalski E, Busch M, Kohn R, Flood J, Ganem D: The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission. Nat Med 1996, 2:918-924.
36. Kedes DH, Ganem D, Ameli N, Bacchetti P, Greenblatt R: The prevalence of serum antibody to human herpesvirus 8 (Kaposi sarcoma-associated herpesvirus) among HIV-seropositive and high-risk HIV-seronegative women. JAMA 1997, 277:478-481.
37. Miller G, Rigsby MO, Heston L, Grogan E, Sun R, Metroka C, Levy JA, Gao S-J, Chang Y, Moore P: Antibodies to butyrate-inducible antigens of Kaposi's sarcoma-associated herpesvirus in patients with HIV-1 infection. N Engl J Med 1996, 334:1292-1297.
38. Simpson GR, Schulz TF, Whitby D, Cook PM, Boshoff C, Rainbow L, Howard MR, Gao S-J, Bohenzky RA, Simmonds P, et al.: Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet 1996, 348:1133-1138.
39. Lin S-F, Sun R, Heston L, Gradoville L, Shedd D, Haglund K, Rigsby M, Miller G: Identification, expression, and immunogenicity of Kaposi's sarcoma-associated herpesvirus-encoded small viral capsid antigen. J Virol 1997, 71:3069-3076.
40. Gao SJ, Kingsley L, Hoover DR, Spira TJ, Rinaldo CR, Saah A, Phair J, Detels R, Parry P, Chang Y, et al.: Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma. N Engl J Med 1996, 335:233-241.
41. Andre S, Schatz O, Bogner JR, Zeichhardt H, Stoffler-Meilicke M, Jahn H-U, Ullrich R, Sonntag A-K, Kehm R, Haas J: Detection of antibodies against viral capsid proteins of human herpesvirus 8 in AIDS-associated Kaposi's sarcoma. J Mol Med 1997, 75:145-152.
42. Monini P, De Lellis L, Fabris M, Rigolin F, Cassai E: Kaposi's sarcoma-associated herpesvirus DNA sequences in prostate tissue and human semen. N Engl J Med 1996, 334:1168-1172.
43. Corbellino M, Bestetti G, Galli M, Parravicini C: Absence of HHV-8 in prostate and semen. N Engl J Med 1996, 335:1237.
44. Tasaka T, Said JW, Morosetti R, Park D, Verbeek W, Nagai M, Takahara J, Koeffler HP: Is Kaposi's sarcoma-associated herpesvirus ubiquitous to urogenital and prostate tissues? Blood 1997, 89:1686-1689.
45. Viviano E, Vitale F, Agello F, Perna AM, Villafrate MR, Bonura F, Arico M, Mazzola G, Romano N: Human herpesvirus type 8 DNA sequences in biological samples of HIV-positive and negative individuals in Sicily. AIDS 1997, 11:607-612.
46. Howard MR, Whitby D, Bahadur G, Suggett F, Boshoff C, Tenant-Flowers M, Schulz TF, Kirk S, Matthews S, Weller IVD, et al.: Detection of human herpesvirus 8 DNA in semen from HIV-infected individuals but not healthy semen donors. AIDS 1997, 11:F15-F19.
47. Lin J-C, Lin S-C, Mar E-C, Pellett PE, Stamey FR, Stewart JA, Spira TJ: Is Kaposi's sarcoma-associated herpesvirus detectable in semen of HIV-infected homosexual men? Lancet 1995, 346:1601-1602.
48. Arvanitakis L, Mesri EA, Nador RG, Said JW, Asch AS, Knowles DM, Cesarman E: Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus. Blood 1996, 88:2648-2654.
49. Cesarman E, Moore PS, Rao PH, Inghirami G, Knowles DM, Chang Y: In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences. Blood 1995, 86:2708-2714.
50. Said JW, Chien K, Takeuchi S, Tasaka T, Asou H, Cho SK, De Vos S, Cesarman E, Knowles DM, Koeffler HP: Kaposi's sarcoma-associated herpesvirus (KSHV or HHV8) in primary effusion lymphomas: ultrastructural demonstration of herpesvirus in lymphoma cells. Blood 1996, 87:4937-4943.
51. Renne R, Zhong W, Herndier B, McGrath M, Abbey N, Kedes D, Ganem D: Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat Med 1996, 2:342-346.
52. Mesri EA, Cesarman E, Arvanitakis L, Rafii S, Moore MAS, Posnett DN, Knowles DM, Asch AS: Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells. J Exp Med 1996, 183:2385-2390.
53. Foreman KE, Friborg J, Kong W-P, Woffendin C, Polverini PJ, Nickoloff BJ, Nabel GJ: Propagation of a human herpesvirus from AIDS-associated Kaposi's sarcoma. N Engl J Med 1997, 336:163-171.
54. Renne R, Lagunoff M, Zhong W, Ganem D: The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virions. J Virol 1996, 70:8151-8154.
55. Decker LL, Shankar P, Khan G, Freeman RB, Dezube BJ, Keberman J, Thorley-Lawson DA: The Kaposi sarcoma-associated herpesvirus (KSHV) is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients. J Exp Med 1996, 184:283-288.
56. Moore PS, Gao S-J, Dominguez G, Cesarman E, Lungu O, Knowles DM, Garber R, Pellett PE, McGeoch DJ, Chang Y: Primary characterization of a herpesvirus agent associated with Kaposi's sarcoma. J Virol 1996, 70:549-558.
57. Russo JJ, Bohenzky RA, Chien M-C, Chen J, Yan M, Maddalena D, Parry JP, Peruzzi D, Edelman IS, Chang Y, et al.: Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc Natl Acad Sci U S A 1996, 93:14862-14867. This complete description of the viral genome identifies numerous putative viral gene products whose homologies to known proteins involved in cell cycle regulation and signal transduction will undoubtedly lead to improved understanding of the molecular basis for KS.
58. Kieff E: Epstein-Barr virus and its replication. In Fundamental Virology. Edited by Fields BN, Knipe DM, Howley PM. Philadelphia: Lippincott-Raven; 1996:1109-1163.
59. Zong J-C, Metroka C, Reitz MS, Nicholas J, Hayward GS: Strain variability among Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genomes: evidence that a large cohort of United States AIDS patients may have been infected by a single common isolate. J Virol 1997, 71:2505-2511.
60. Jung JU, Desrosiers RC: Identification and characterization of the herpesvirus saimiri oncoprotein STP-C488. J Virol 1991, 65:6953-6960.
61. Moore PS, Boshoff C, Weiss RA, Chang Y: Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science 1996, 274:1739-1744.
62. Nicholas J, Ruvolo V, Zong J, Ciufo D, Guo H-G, Reitz MS, Hayward GS: A single 13-kilobase divergent locus in the Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genome contains nine open reading frames that are homologous to or related to cellular proteins. J Virol 1997, 71:1963-1974.
63. Nicholas J, Cameron KR, Honess RW: Herpesvirus saimiri encodes homologues of G protein-couple receptors and cyclins. Nature 1992, 355:362-365.
64. Albrecht J-C, Nicholas J, Biller D, Cameron KR, Biesinger B, Newman C, Wittmann S, Craxton MA, Coleman H, Fleckenstein B, et al.: Primary structure of the herpesvirus saimiri genome. J Virol 1992, 66:5047-5058.
65. Sarid R, Sato T, Bohenzky RA, Russo JJ, Chang Y: Kaposi's sarcoma-associated herpesvirus encodes a functional Bcl-2 homologue. Nat Med 1997, 3:293-298.
66. Reed JC: Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance. Curr Opin Oncol 1995, 7:541-546.
67. Cheng EHY, Nicholas J, Bellows D, Hayward GS, Guo HG, Reitz MS, Hardwick JM: A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak. Proc Natl Acad Sci USA 1997, 94:690-694.
68. Sherr CJ: D-type cyclins. Trends Biol Sci 1995, 20:187-190.
69. Sherr CJ: Cancer cell cycles. Science 1996, 274:1672-1677.
70. Elledge SJ: Cell cycle checkpoints: preventing an identity crisis. Science 1996, 274:1664-1671.
71. Li M, Lee H, Yoon D-W, Albrecht J-C, Fleckenstein B, Neipel F, Jung JU: Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin. J Virol 1997, 71:1984-1991.
72. Chang Y, Moore PS, Talbot SJ, Boshoff CH, Zarkowska T, Godden-Kent D, Paterson H, Weiss RA, Mittnacht S: Cyclin encoded by KS herpesvirus. Nature 1996, 382:410.
73. Nevins JR, Vogt PK: Cell transformation by viruses. In Fundamental Virology. Edited by Fields BN, Knipe DM, Howley PM, Philadelphia: Lippincott-Raven; 1996:267-309.
74. Young D, Waitches G, Birchmeier C, Fasano O, Wigler M: Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains. Cell 1986, 45:711-719
75. Julius D, Livelli TL, Jessell TM, Axel R: Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation. Science 1989, 244:1057-1062.
76. Allen LF, Lefkowitz RJ, Caron MG, Cotecchia S: G-protein coupled receptor genes as protooncogenes: Constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity. Proc Natl Acad Sci U S A 1991, 88:11354-11358.
77. Gutkind JS, Novotny EA, Brann MR, Robbins KC: Muscarinic acetylcholine receptor subtypes as agonist dependent oncogenes. Proc Natl Acad Sci U S A 1991, 88:4703-4707.
78. Arvanitakis L, Geras-Raaka E, Varma A, Gershengorn MC, Cesarman E: Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation. Nature 1997, 385:347-350.
79. Cesarman E, Nador RG, Bai F, Bohenzky RA Russo JJ, Moore PS, Chang Y, Knowles DM: Kaposi's sarcoma-associated herpesvirus contains G protein-coupled receptor and cyclin D homologs which are expressed in Kaposi's sarcoma and malignant lymphoma. J Virol 1996, 70:8218-8223.
80. Guo H-G, Browning P, Nichols, Hayward GS, Tschachler E, Jiang Y-W, Sadowska M, Raffeld M, Colombini S, Gallo RC, et al.: Characterization of a chemokine receptor-related gene in human herpesvirus 8 and its expression in Kaposi's sarcoma. Virology 1997, 228:371-378.
81. Nakamura S, Salahuddin SK, Biberfeld P, Ensoli B, Markham PD, Wong-Staal F, Gallo RC: Kaposi's sarcoma cells: long-term culture with factor from retrovirus-infected CD4+ T cells. Science 1988, 242:426-430.
82. Ensoli B, Nakamura S, Salahuddin SZ, Biberfeld P, Larsson L, Beaver B, Wong-Staal L, RCG: AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects. Science 1989, 243:223-226.
83. Samaniego F, Markham PD, Gendelman R, Gallo RC, Ensoli B: Inflammatory cytokines induce endothelial cells to produce and release basic fibroblast growth factor and to promote Kaposi's sarcoma-like lesions in nude mice. J Immunol 1997, 158:1887-1894.
84. Miles SA, Rezai AR, Salazar-Gonzalez JF, Vander Meyden M, Stevens RH, Logan DM, Mitsuyasu RT, Taga T, Kishimoto T, Martinez-Maza O: AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6. Proc Natl Acad Sci U S A 1990, 87:4068-4072.
85. Neipel F, Albrecht J-C, Ensser A, Huang Y-Q, Li JJ, Freidman-Kein AE, Fleckenstein B: Human herpesvirus 8 encodes a homolog of interleukin-6. J Virol 1997, 71:839-842.
86. Nicholas J, Ruvolo VR, Burns WH, Sandford G, Wan X, Ciufo D, Hendrickson SB, Guo H-G, Hayward GS, Reitz MS: Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6. Nat Med 1997, 3:287-292.
87. Lachant NA, Sun N, Leong LA, Oseas RS, Price HE: Multicentric angiofollicular lymph node hyperplasia (Castleman's disease) followed by Kaposi's sarcoma in two homosexual males with the acquired immunodeficiency syndrome (AIDS). Am J Clin Pathol 1984, 83:27-33.
88. Chen KTK: Multicentric Castleman's disease and Kaposi's sarcoma. Am J Surg Pathol 1984, 8:287-293.
89. Rywlin AM, Rosen L, Cabello B: Coexistence of Castleman's disease and Kaposi's sarcoma: report of a case and a speculation. Am J Dermatopathol 1983, 5:277-281.
90. Harris N: Hypervascular follicular hyperplasia and Kaposi's sarcoma in patients at risk for AIDS. N Engl J Med 1984, 310:462.
91. Frizzera G, Peterson BA, Bayrd ED, Goldman A: Asystemic lymphoproliferative disorder with morphologic features of Castleman's disease: clinical findings and clinicopathologic correlations in 15 patients. J Clin Oncol 1985, 3:1202-1216.
92. Solier J, Grollet L, Oksenhendler E, Cacoub P, Cazals-Hatem D, Babinet P, d'Agay M-F, Clauvel J-P, Raphael M, Degos L, et al.: Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 1995, 86:1276-1280.
93. Yoshizaki K, Matsuda, T, Nishimoto N, Kuritani T, Taeho L, Aozasa K, Nakahata T, Kawai H, Tagoh H, Komori T, et al.: Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's Disease. Blood 1989, 74:1360-1367.
94. Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW: Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. J Clin Invest 1990, 86:592-599.
95. Weber J, Yang JC, Topalian SL, Parkinson DR, Schwartzentruber DS, Ettinghausen SE, Gunn H, Mixon A, Kim H, Cole D, et al.: Phase I trial of subcutaneous interleukin-6 in patients with advanced malignancies. J Clin Oncol 1993, 11:499-506.
96. Knowles DM, Chamulak GA, Subar M, Burke JS, Dugan M, Wernz J, Slywotzky C, Pelicci P-G, Dalla-Favera B, Raphael B: Lymphoid neoplasia associated with the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 1988, 108:744-753.
97. Ridolfo AL, Saritambrogio S, Mainini F, Vago L, Gervasoni C, Gori A, Parravicini C, D'Arminio Monforte A, Galli M: High frequency of non-Hodgkin's lymphoma in patients with HIV-associated Kaposi's sarcoma. AIDS 1996, 10:181-185.
98. Sifai B, Mike V, Giraldo G, Beth E, Good RA: Association of Kaposi's sarcoma with second primary malignancies. Possible etiopathogenic implications. Cancer 1980, 45:1472-1479.
99. Walts AE, Shintaku IP, Said JW: Diagnosis of malignant lymphoma in effusions from patients with AIDS by gene rearrangement Am J Clin Pathol 1990, 94:170-175.
100. Chadburn A, Cesarman E, Jagirdar J, Subar M, Mir RN, Knowles DM: CD30 (Ki-1) positive anaplastic large cell lymphomas in individuals infected with the human immunodeficiency virus. Cancer 1993, 72:3078-3090.
101. Ansari MQ, Dawson DB, Nador R, Rutherford C, Schneider NR, Latimer MJ, Picker L, Knowles DM, McKenna RW: Primary body cavity-based AIDS-related lymphomas. Am J Clin Pathol 1996, 105:221-229.
102. Knowles DM, Inghirami G, Ubriaco A, Dalla-Favera R: Molecular genetic analysis of three AIDS-associated neoplasms of uncertain lineage demonstrates their B-cell derivation and the possible pathogenetic role of the Epstein-Barr virus. Blood 1989, 73:792-799.
103. Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM: Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med 1995, 332:1186-1191.
104. Gessain A, Briere J, Angelin-Duclos C, Valensi F, Merle Beral H, Davi F, Nicola M-A, Sudaka A, Fouchard N, Gabarre J, et al.: Human herpes virus 8 (Kaposi's sarcoma herpes virus) and malignant lymphoproliferations in France: a molecular study of 250 cases including two AIDS-associated body cavity based lymphomas. Leukemia 1997, 11:266-272.
105. Jaffe ES: Primary body cavity-based AIDS-related lymphomas. Evolution of a new disease entity. Am J Clin Pathol 1996, 105:141-143.
106. Carbone A, Tirelli U, Gloghini A, Pastore C, Vaccher E, Gaidano G: Herpesvirus-like DNA sequences selectively cluster with body cavity-based lymphomas throughout the spectrum of AIDS-related lymphomatous effusions. Eur J Cancer 1996, 32A:555-556.
107. Nador RG, Cesarman E, Chadburn A, Dawson DB, Ansari MQ, Said J, Knowles DM: Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus. Blood 1996, 88:645-656.
108. Cesarman E, Nador RG, Aozasa K, Delsol G, Said JW, Knowles DM: Kaposi's sarcoma-associated herpesvirus in non-AIDS-related lymphomas occurring in body cavities. Am J Pathol 1996, 149:53-57.
109. Nador RG, Cesarman E, Knowles DM: Herpes-like DNA sequences in a body cavity-based lymphoma in an HIV-negative patient N Engl J Med 1995, 333:943.
110. Ensoli B, Barillari G, Salahuddin SZ, Gallo RC, Wong-Staal F: Tat protein of HIV-1 stimulates growth of cells derived Kaposi's sarcoma lesions of AIDS patients. Nature 1990, 345:84-86.
111. Ensoli B, Gendelman R, Markham P, Fiorelli V, Colombini S, Raffeld M, Cafaro A, Chang H-K, Brady JN, Gallo RC: Synergy between basic fibroblast growth factor and HIV-1 tat protein in induction of Kaposi's sarcoma. Nature 1994, 371:674-680.
112. Doutrelepont J-M, De Pauw L, Gruber SA, Dunn DL, Qunibi W, Kinnaert P, Vereerstraeten P, Penn I, Abramowicz D: Renal transplantation exposes patients with previous Kaposi's sarcoma to a high risk of recurrence. Transplantation 1996, 62:463-466.
113. Di Luca D, Dolcetti R, Bigoni B, Carbone A, de Lellis L, Boiocchi M, Cassai E: Letter to the editor. J Infect Dis 1996, 174:669-670.
114. Humphrey RW, O'Brien TR, Newcomb FM, Nishihara H, Ramos GA, Saville MW, Goedert JJ, Straus SE, Yarchaon R: Kaposi's sarcoma (KS)-associated herpesvirus-like DNA sequences in peripheral blood mononuclear cells: association with KS and persistence in patients receiving anti-herpesvirus drugs. Blood 1996, 88:297-301.
115. Centers for Disease Control Task Force on Kaposi's Sarcoma and Opportunistic Infections: Epidemiologic aspects of the current outbreak of Kaposi's sarcoma and opportunistic infections. New Engl J Med 1982, 282:248-252.