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Volumn 10, Issue 2, 1997, Pages 49-62

Immunological Gene Therapy Approaches for Malignant Melanoma

Author keywords

Cancer; T lymphocytes; Tumor antigens; Tumor vaccine

Indexed keywords

CD8 ANTIGEN; CYTOKINE; TUMOR ANTIGEN; TUMOR VACCINE;

EID: 0030816345     PISSN: 16605527     EISSN: 16605535     Source Type: Journal    
DOI: 10.1159/000211469     Document Type: Article
Times cited : (7)

References (86)
  • 1
    • 0027595949 scopus 로고
    • The basic science of gene therapy
    • Mulligan RC: The basic science of gene therapy. Science 1993:260: 926-932.
    • (1993) Science , vol.260 , pp. 926-932
    • Mulligan, R.C.1
  • 4
    • 0028899382 scopus 로고
    • The gene as the drug
    • Crystal RG: The gene as the drug. Nat Med 1995;1:15-17.
    • (1995) Nat Med , vol.1 , pp. 15-17
    • Crystal, R.G.1
  • 6
    • 0011816171 scopus 로고    scopus 로고
    • Human gene marker/therapy clinical protocols
    • Recombinant DNA Advisory Committee: Human gene marker/therapy clinical protocols. Hum Gene Thcr 1996:7:567-588.
    • (1996) Hum Gene Thcr , vol.7 , pp. 567-588
  • 7
    • 0029450025 scopus 로고
    • End-of-the-year potpourri - 1995
    • Anderson WF: End-of-the-year potpourri - 1995. Hum Gene Ther 1995:6:1505-1506.
    • (1995) Hum Gene Ther , vol.6 , pp. 1505-1506
    • Anderson, W.F.1
  • 8
    • 0028293089 scopus 로고
    • Targeted therapy for malignant melanoma
    • Han IR, Vile RG: Targeted therapy for malignant melanoma. Curr Opin Oncol 1994:6:221-225.
    • (1994) Curr Opin Oncol , vol.6 , pp. 221-225
    • Han, I.R.1    Vile, R.G.2
  • 9
    • 0028298850 scopus 로고
    • Tumor antigens. A new look for the 1990s
    • Pardoll DM: Tumor antigens. A new look for the 1990s. Nature 1994: 369:357-358.
    • (1994) Nature , vol.369 , pp. 357-358
    • Pardoll, D.M.1
  • 11
    • 33747588713 scopus 로고    scopus 로고
    • Gene therapy approaches for malignant melanoma - Treatment strategics and therapeutic potential of adenovirus-mediated gene transfer
    • (submitted)
    • Bonnekoh B, Bickenbach JR, Roop DR: Gene therapy approaches for malignant melanoma - Treatment strategics and therapeutic potential of adenovirus-mediated gene transfer. Proc Am Acad Physicians (submitted).
    • Proc am Acad Physicians
    • Bonnekoh, B.1    Bickenbach, J.R.2    Roop, D.R.3
  • 14
    • 0002724633 scopus 로고
    • Tumor immunology
    • Paul WE (ed), ed 3. New York, Raven Press
    • Schreiber H: Tumor immunology: in Paul WE (ed): Fundamental Immunology, ed 3. New York, Raven Press. 1993. pp 1143-1178.
    • (1993) Fundamental Immunology , pp. 1143-1178
    • Schreiber, H.1
  • 17
    • 0029864363 scopus 로고    scopus 로고
    • Docs B7-I expression confer antigen-presenting cell capacity to tumors in vivo?
    • Huang AYC, Brude AT, Pardoll DM, Levitsky HI: Docs B7-I expression confer antigen-presenting cell capacity to tumors in vivo? J Exp Med 1996;183:769-776.
    • (1996) J Exp Med , vol.183 , pp. 769-776
    • Huang, A.1    Brude, A.T.2    Pardoll, D.M.3    Levitsky, H.I.4
  • 18
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
    • Huang AYC, Golumbek P, Ahmad-zadeh M, Jaffec E, Pardoll D, Levitsky H: Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science 1994;264:961-965.
    • (1994) Science , vol.264 , pp. 961-965
    • Huang, A.1    Golumbek, P.2    Ahmad-Zadeh, M.3    Jaffec, E.4    Pardoll, D.5    Levitsky, H.6
  • 19
    • 0029927928 scopus 로고    scopus 로고
    • A new foreign policy: MHC class I molecules monitor the outside of the world
    • Rock KL: A new foreign policy: MHC class I molecules monitor the outside of the world. Immunol Today 1996;17:131-137.
    • (1996) Immunol Today , vol.17 , pp. 131-137
    • Rock, K.L.1
  • 21
    • 0002033892 scopus 로고
    • De-Vita VT. Heilman S. Rosenberg SA (eds)Biology Therapy of Cancer, ed 2. Philadelphia, Lippincott
    • Rcstifo NP, Wunderlich JR: Biology of cellular immune responses: in De-Vita VT. Heilman S. Rosenberg SA (eds): Biology Therapy of Cancer, ed 2. Philadelphia, Lippincott, 1995, pp 3-37.
    • (1995) Biology of Cellular Immune Responses , pp. 3-37
    • Rcstifo, N.P.1    Wunderlich, J.R.2
  • 22
    • 0028245977 scopus 로고
    • Recent advances in cutaneous melanoma oncogenesis research
    • Dooley TP: Recent advances in cutaneous melanoma oncogenesis research. Oncol Res 1994:6:1-9.
    • (1994) Oncol Res , vol.6 , pp. 1-9
    • Dooley, T.P.1
  • 23
    • 0029442060 scopus 로고
    • Mutation and cancer: A personal odyssey
    • Knudson AG: Mutation and cancer: A personal odyssey. Adv Cancer Res 1995;67:1-23.
    • (1995) Adv Cancer Res , vol.67 , pp. 1-23
    • Knudson, A.G.1
  • 24
    • 0028959985 scopus 로고
    • Genes involved in melanoma susceptibility and progression
    • Albino AP: Genes involved in melanoma susceptibility and progression. Curr Opin Oncol 1995:7:162-169.
    • (1995) Curr Opin Oncol , vol.7 , pp. 162-169
    • Albino, A.P.1
  • 26
    • 0029125899 scopus 로고
    • A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma
    • Coulie P, Lehmann F, Lethé B, Herman J, Lurquin C, Andrawiss M, Boon T: A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma. Proc Natl Acad Sei USA 1995;192:7976-7980.
    • (1995) Proc Natl Acad Sei USA , vol.192 , pp. 7976-7980
    • Coulie, P.1    Lehmann, F.2    Lethé, B.3    Herman, J.4    Lurquin, C.5    Rawiss, M.6    Boon, T.7
  • 28
    • 0028298224 scopus 로고
    • Cancer antigens: Immune recognition of self and altered self
    • Houghton AN: Cancer antigens: Immune recognition of self and altered self. J Exp Med 1994;180:1-4.
    • (1994) J Exp Med , vol.180 , pp. 1-4
    • Houghton, A.N.1
  • 30
    • 0006230297 scopus 로고
    • Genes coding for tumor antigens recognized by T lymphocytes;
    • DeVita VT, Heilman S. Rosenberg SA (eds), ed 2. Philadelphia. Lippincott
    • Kawakami Y, Robbins PF: Genes coding for tumor antigens recognized by T lymphocytes; in DeVita VT, Heilman S. Rosenberg SA (eds): Biology Therapy of Cancer, ed 2. Philadelphia. Lippincott. 1995. pp 53-64.
    • (1995) Biology Therapy of Cancer , pp. 53-64
    • Kawakami, Y.1    Robbins, P.F.2
  • 31
    • 0344653416 scopus 로고
    • Tumoranti-gens recognized by immune cells
    • DeVita VT. Heilman S. Rosenberg SA (eds), ed 2. Philadelphia, Lippincott
    • Storkus WJ, Lotze MT: Tumoranti-gens recognized by immune cells: in DeVita VT. Heilman S. Rosenberg SA (eds): Biology Therapy of Cancer, ed 2. Philadelphia, Lippincott. 1995. pp 64-77.
    • (1995) Biology Therapy of Cancer , pp. 64-77
    • Storkus, W.J.1    Lotze, M.T.2
  • 33
    • 0030048081 scopus 로고    scopus 로고
    • A tyrosinase nona-peptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lympho-cvtes
    • Brichard VG, Herman J, Van Pel A, Wildmann C, Gaugier B, Wölfel T, Boon T, Lethe B: A tyrosinase nona-peptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lympho-cvtes. EurJ Immunol 1996:26:224-230.
    • (1996) Eurj Immunol , vol.26 , pp. 224-230
    • Brichard, V.G.1    Herman, J.2    Van Pel, A.3    Wildmann, C.4    Gaugier, B.5    Wölfel, T.6    Boon, T.7    Lethe, B.8
  • 35
    • 0027165558 scopus 로고
    • The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas
    • Brichard V, Van Pei A, Wölfel T, Wölfel C, De Plaen E, Lethe B. Coulie P. Boon T: The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J Exp Med 1993:178:489-495.
    • (1993) J Exp Med , vol.178 , pp. 489-495
    • Brichard, V.1    Van Pei, A.2    Wölfel, T.3    Wölfel, C.4    De Plaen, E.5    Lethe, B.6    Coulie, P.7    Boon, T.8
  • 38
    • 0027015406 scopus 로고
    • A pilot study of immunization with HLA-A2 matched allogeneic melanoma cells that secrete interleukin-2 in patients with metastatic melanoma
    • Gansbacher B: A pilot study of immunization with HLA-A2 matched allogeneic melanoma cells that secrete interleukin-2 in patients with metastatic melanoma. Hum Gene Ther 1992:3:677-690.
    • (1992) Hum Gene Ther , vol.3 , pp. 677-690
    • Gansbacher, B.1
  • 39
    • 0027304075 scopus 로고
    • Immunization with interleukin-2 transfected melanoma cells. A phase I-II study in patients with metastatic melanoma
    • Osanto S: Immunization with interleukin-2 transfected melanoma cells. A phase I-II study in patients with metastatic melanoma. Hum Gene Ther 1993:4:323-330.
    • (1993) Hum Gene Ther , vol.4 , pp. 323-330
    • Osanto, S.1
  • 40
    • 0037670275 scopus 로고
    • Gene modification of tumors
    • De-Vita VT. Heilman S. Rosenberg SA (eds), ed 2. Philadelphia. Lippincott
    • Jaffee EM, Hurwitz H, Pardoll DM: Gene modification of tumors: in De-Vita VT. Heilman S. Rosenberg SA (eds): Biology Therapy of Cancer, ed 2. Philadelphia. Lippincott, 1995. pp 774-783.
    • (1995) Biology Therapy of Cancer , pp. 774-783
    • Jaffee, E.M.1    Hurwitz, H.2    Pardoll, D.M.3
  • 41
    • 0028898188 scopus 로고
    • Scientific aspects of gene therapy in melanoma
    • Rankin EM: Scientific aspects of gene therapy in melanoma. Curr Opin Oncol 1995;7:192-196.
    • (1995) Curr Opin Oncol , vol.7 , pp. 192-196
    • Rankin, E.M.1
  • 42
    • 0030070340 scopus 로고    scopus 로고
    • Dendritic cells as adjuvants for class 1 major histocompatibility complex-restricted antitumor immunity
    • Young JW, Inaba K: Dendritic cells as adjuvants for class 1 major histocompatibility complex-restricted antitumor immunity. J Exp Med 1996:183:7-11.
    • (1996) J Exp Med , vol.183 , pp. 7-11
    • Young, J.W.1    Inaba, K.2
  • 43
    • 0030048724 scopus 로고    scopus 로고
    • Peptide-pulsed dendritic cells induce antigen-specific. CTL-mediated protective tumor immunity
    • Celluzzi CM, Mayordomo JI, Storkus WJ, Lotze MT, Falo LD Jr: Peptide-pulsed dendritic cells induce antigen-specific. CTL-mediated protective tumor immunity. J Exp Med 1996:183:283-287.
    • (1996) J Exp Med , vol.183 , pp. 283-287
    • Celluzzi, C.M.1    Mayordomo, J.I.2    Storkus, W.J.3    Lotze, M.T.4    Falo, L.D.5
  • 44
    • 0030058647 scopus 로고    scopus 로고
    • Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines
    • Zitvogel L, Mayordomo JI, Tjandra-wan T, DcLeo AB, Clarke MR, Lotze MT, Storkus WJ: Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines. J Exp Med 1996;183:87-97.
    • (1996) J Exp Med , vol.183 , pp. 87-97
    • Zitvogel, L.1    Mayordomo, J.I.2    Tjandra-Wan, T.3    Dcleo, A.B.4    Clarke, M.R.5    Lotze, M.T.6    Storkus, W.J.7
  • 45
    • 0028786092 scopus 로고
    • Dendritic cells generated from peripheral blood transfected with human tyrosinase induce specific T cell activation
    • Alijagic S, Moller P, Artuc M, Jur-govsky K, Czarnetzki BM, Schadcn-dorf D: Dendritic cells generated from peripheral blood transfected with human tyrosinase induce specific T cell activation. Eur J Immunol 1995;25:3100-3107.
    • (1995) Eur J Immunol , vol.25 , pp. 3100-3107
    • Alijagic, S.1    Moller, P.2    Artuc, M.3    Jur-Govsky, K.4    Czarnetzki, B.M.5    Schadcn-Dorf, D.6
  • 46
    • 0028208910 scopus 로고
    • Effective tumor vaccine generated by fusion of hepatoma cells with activated B cells
    • Guo Y, Wu M, Chen H, Wang X, Liu G. Li G, Ma J. Sy M-S: Effective tumor vaccine generated by fusion of hepatoma cells with activated B cells. Science 1994:263:518-520.
    • (1994) Science , vol.263 , pp. 518-520
    • Guo, Y.1    Wu, M.2    Chen, H.3    Wang, X.4    Liu, G.5    Li, G.6    Ma, J.7    Sy, M.-S.8
  • 49
    • 0026472495 scopus 로고
    • Retroviral gene transfer induced constitutive expression of interleukin-2 or interferon-y in irradiated human melanoma cells
    • Gansbacher B, Zier K, Cronin K, Hantzopoulos PA, Bouchard B, Houghton A, Gilboa H, Golde D: Retroviral gene transfer induced constitutive expression of interleukin-2 or interferon-y in irradiated human melanoma cells. Blood 1992: 80:2817-2825.
    • (1992) Blood , vol.80 , pp. 2817-2825
    • Gansbacher, B.1    Zier, K.2    Cronin, K.3    Hantzopoulos, P.A.4    Bouchard, B.5    Houghton, A.6    Gilboa, H.7    Golde, D.8
  • 50
    • 0028826973 scopus 로고
    • Analysis of TCR usage in human tumors: A new tool for assessing tumor-specific immune responses
    • Scnsi M, Parmiani G: Analysis of TCR usage in human tumors: A new tool for assessing tumor-specific immune responses. Immunol Today 1995:16:588-595.
    • (1995) Immunol Today , vol.16 , pp. 588-595
    • Scnsi, M.1    Parmiani, G.2
  • 51
    • 0028932731 scopus 로고
    • The CTL's kiss of death
    • Berke G: The CTL's kiss of death. Cell 1995;81:9-12.
    • (1995) Cell , vol.81 , pp. 9-12
    • Berke, G.1
  • 52
    • 0027295140 scopus 로고
    • Interleukin 3 enhances development of tumor-reactive cytotoxic cells by a CD4-depcndcnt mechanism
    • Pulaski BA, McAdam AJ, Hutter EK, Biggar S, Lord EM. Frelinger JG: Interleukin 3 enhances development of tumor-reactive cytotoxic cells by a CD4-depcndcnt mechanism. Cancer Res 1993:53:2112-2117.
    • (1993) Cancer Res , vol.53 , pp. 2112-2117
    • Pulaski, B.A.1    McAdam, A.J.2    Hutter, E.K.3    Biggar, S.4    Lord, E.M.5    Frelinger, J.G.6
  • 55
    • 0028266502 scopus 로고
    • Further studies of the therapeutic effects of murine melanoma-specific monoclonal antibodies
    • Law LW, Vieira WD, Hearing VJ, Gersten DM: Further studies of the therapeutic effects of murine melanoma-specific monoclonal antibodies. Biochim Biophys Acta 1994: 1226:105-109.
    • (1994) Biochim Biophys Acta , vol.1226 , pp. 105-109
    • Law, L.W.1    Vieira, W.D.2    Hearing, V.J.3    Gersten, D.M.4
  • 57
    • 0344653479 scopus 로고
    • Tumor antigens recognized by monoclonal antibodies
    • DeVita VT. Hellntan S, Rosenberg SA (eds), ed 2. Philadelphia, Lippincott
    • Ferrone S, Chu TM, Hellstrom I, Hellstrom KE: Tumor antigens recognized by monoclonal antibodies: in DeVita VT. Hellntan S, Rosenberg SA (eds): Biology Therapy of Cancer, ed 2. Philadelphia, Lippincott, 1995, pp 77-86.
    • (1995) Biology Therapy of Cancer , pp. 77-86
    • Ferrone, S.1    Chu, T.M.2    Hellstrom, I.3    Hellstrom, K.E.4
  • 58
    • 0025279832 scopus 로고
    • Induction of antibody-dependent cellular cytotoxicity in vivo by IFN-a and its antitumor efficacy against established B16 melanoma liver mctastascs when combined with specific anti-B16 monoclonal antibod
    • Eisenthal A, Cameron RB, Rosenberg SA: Induction of antibody-dependent cellular cytotoxicity in vivo by IFN-a and its antitumor efficacy against established B16 melanoma liver mctastascs when combined with specific anti-B16 monoclonal antibody. J Immunol 1990:144: 4463-4471.
    • (1990) J Immuno , vol.144 , pp. 4463-5447
    • Eisenthal, A.1    Cameron, R.B.2    Rosenberg, S.A.3
  • 59
    • 0026813323 scopus 로고
    • The immunotherapy and gene therapy of cancer
    • Rosenberg SA: The immunotherapy and gene therapy of cancer. J Clin Oncol 1992;10:180-199.
    • (1992) J Clin Oncol , vol.10 , pp. 180-199
    • Rosenberg, S.A.1
  • 61
    • 0025147441 scopus 로고
    • Treatment of metastatic melanoma with an autologous tumor-cell vaccine: Clinical and immunologic results in 64 patients
    • Bcrd D, Maguire HC, McCue P, Mastrangclo MJ: Treatment of metastatic melanoma with an autologous tumor-cell vaccine: Clinical and immunologic results in 64 patients. J Clin Oncol 1990:8:1858-1867.
    • (1990) J Clin Oncol , vol.8 , pp. 1858-1867
    • Bcrd, D.1    Maguire, H.C.2    McCue, P.3    Mastrangclo, M.J.4
  • 63
    • 0028001082 scopus 로고
    • Increasing tumor immunogenicity by genetic modification
    • Blankcnstcin T: Increasing tumor immunogenicity by genetic modification. Eur J Cancer 1994;30A: 1182-1187.
    • (1994) Eur J Cancer , vol.30A , pp. 1182-1187
    • Blankcnstcin, T.1
  • 64
    • 0029057043 scopus 로고
    • Loss of HLA class I antigens by melanoma cells: Molecular mechanisms, functional significance and clinical relevance
    • Ferrone S, Marineóla FM: Loss of HLA class I antigens by melanoma cells: Molecular mechanisms, functional significance and clinical relevance. Immunol Today 1995:16: 487-494.
    • (1995) Immunol Today , vol.16 , pp. 487-494
    • Ferrone, S.1    Marineóla, F.M.2
  • 66
    • 0028017985 scopus 로고
    • Cancer escape from immune surveillance: How can it be overcome by gene transfer?
    • Bruyns C, Gérard C, Velu T: Cancer escape from immune surveillance: How can it be overcome by gene transfer? Eur J Cancer 1994;30A: 1176-1181.
    • (1994) Eur J Cancer , vol.30A , pp. 1176-1181
    • Bruyns, C.1    Gérard, C.2    Velu, T.3
  • 67
    • 0029080474 scopus 로고
    • Exposing the immunology of naked DNA vaccines
    • Pardoll DM, Beckcrleg AM: Exposing the immunology of naked DNA vaccines. Immunity 1995:3:165-169.
    • (1995) Immunity , vol.3 , pp. 165-169
    • Pardoll, D.M.1    Beckcrleg, A.M.2
  • 68
    • 0028589416 scopus 로고
    • Experimental and clinical studies of cytokine gene-modified tumor cells
    • Tepper RI, Mule JJ: Experimental and clinical studies of cytokine gene-modified tumor cells. Hum Gene Ther 1994:5:153-164.
    • (1994) Hum Gene Ther , vol.5 , pp. 153-164
    • Tepper, R.I.1    Mule, J.J.2
  • 69
    • 0029947360 scopus 로고    scopus 로고
    • IL-2 gene therapy of solid tumors: An approach for the prevention of signal transduction defects in T cells
    • Zier KS, Gansbacher B: IL-2 gene therapy of solid tumors: An approach for the prevention of signal transduction defects in T cells. J Mol Med 1996;74:127-134.
    • (1996) J Mol Med , vol.74 , pp. 127-134
    • Zier, K.S.1    Gansbacher, B.2
  • 70
    • 0028908324 scopus 로고
    • Paracrine cytokine adjuvants in cancer immunotherapy
    • Pardoll DM: Paracrine cytokine adjuvants in cancer immunotherapy. Annu Rev Immunol 1995:13:399-415.
    • (1995) Annu Rev Immunol , vol.13 , pp. 399-415
    • Pardoll, D.M.1
  • 72
    • 0028815475 scopus 로고
    • Generation of therapeutic T-lymphocytes after in vivo tumor transfection with an allogeneic class I major histocompatibility complex gene
    • Wahl WL, Strome SE, Nabel GJ, Plautz GE, Cameron MJ, San H, Fox BA, Shu S, Chang AE: Generation of therapeutic T-lymphocytes after in vivo tumor transfection with an allogeneic class I major histocompatibility complex gene. J Immunother 1995;17:1-11.
    • (1995) J Immunother , vol.17 , pp. 1-11
    • Wahl, W.L.1    Strome, S.E.2    Nabel, G.J.3    Plautz, G.E.4    Cameron, M.J.5    San, H.6    Fox, B.A.7    Shu, S.8    Chang, A.E.9
  • 73
    • 0026317633 scopus 로고
    • Predominance of the metastatic phenotype in somatic cell hybrids of the K-1735 murine melanoma
    • Starosclsky AH, Pathak S, Chema-jovsky Y, Tucker SL, Fidler IJ: Predominance of the metastatic phenotype in somatic cell hybrids of the K-1735 murine melanoma. Cancer Res 1991;51:6292-6298.
    • (1991) Cancer Res , vol.51 , pp. 6292-6298
    • Starosclsky, A.H.1    Pathak, S.2    Chema-Jovsky, Y.3    Tucker, S.L.4    Fidler, I.J.5
  • 74
    • 0028867835 scopus 로고
    • Manipulation of costimulatory signals to enhance antitumor T-cell response
    • Allison JP, Hurwitz AA, Leach DR: Manipulation of costimulatory signals to enhance antitumor T-cell response. CurrOpin Immunol 1995:7: 682-686.
    • (1995) Curropin Immunol , vol.7 , pp. 682-686
    • Allison, J.P.1    Hurwitz, A.A.2    Leach, D.R.3
  • 75
    • 0026592691 scopus 로고
    • Epidemiology and prognostic factors in malignant melanoma
    • Rigel DS: Epidemiology and prognostic factors in malignant melanoma. Ann Plast Surg 1992;28:7-8.
    • (1992) Ann Plast Surg , vol.28 , pp. 7-8
    • Rigel, D.S.1
  • 76
    • 0028592689 scopus 로고
    • An overview of skin cancers - Incidence and causation
    • Marks R: An overview of skin cancers - Incidence and causation. Cancer 1995;75(suppl):607-612.
    • (1995) Cancer , vol.75 , pp. 607-612
    • Marks, R.1
  • 77
    • 0030023023 scopus 로고    scopus 로고
    • The paradoxical association of regression with a poor prognosis in melanoma contrasted with a good prognosis in kcratoacanthoma
    • Prehn RT: The paradoxical association of regression with a poor prognosis in melanoma contrasted with a good prognosis in kcratoacanthoma. Cancer Res 1996:56:937-940.
    • (1996) Cancer Res , vol.56 , pp. 937-940
    • Prehn, R.T.1
  • 78
    • 0028937132 scopus 로고
    • Immunobiology and immunotherapy of melanoma
    • Mukherji B, Chakraborty NG: Immunobiology and immunotherapy of melanoma. Curr Opin Oncol 1995;7:175-184.
    • (1995) Curr Opin Oncol , vol.7 , pp. 175-184
    • Mukherji, B.1    Chakraborty, N.G.2
  • 81
    • 0029872770 scopus 로고    scopus 로고
    • Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene
    • Stingl G: Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene. Hum Gene Ther 1996;7:551-563.
    • (1996) Hum Gene Ther , vol.7 , pp. 551-563
    • Stingl, G.1
  • 82
    • 0029116933 scopus 로고
    • In situ interleukin-4 gene expression in cancer patients treated with genetically modified tumor vaccine
    • Sumiami Y, Elder EM, Lotze MT, Whiteside TL: In situ interleukin-4 gene expression in cancer patients treated with genetically modified tumor vaccine. J Immunother 1995: 17:238-248.
    • (1995) J Immunother , vol.17 , pp. 238-248
    • Sumiami, Y.1    Elder, E.M.2    Lotze, M.T.3    Whiteside, T.L.4
  • 85
    • 0029202841 scopus 로고
    • Immunotherapy and gene therapy of cancer
    • Ettinghausen SE, Rosenberg SA: Immunotherapy and gene therapy of cancer. AdvSurg 1995;28:223-254.
    • (1995) Advsurg , vol.28 , pp. 223-254
    • Ettinghausen, S.E.1    Rosenberg, S.A.2
  • 86
    • 0029868425 scopus 로고    scopus 로고
    • Adoptive immunotherapy of cancer with activated lymph node cells primed in vivo with autologous tumor cells transduced with the GM-CSF gene
    • Chang AE: Adoptive immunotherapy of cancer with activated lymph node cells primed in vivo with autologous tumor cells transduced with the GM-CSF gene. Hum Gene Ther 1996:7:773-792.
    • (1996) Hum Gene Ther , vol.7 , pp. 773-792
    • Chang, A.E.1


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