Coordinate regulation of G- and C strand length during new telomere synthesis

Molecular Biology of the Cell

Volumn 8, Issue 11, 1997, Pages 2145-2155

  Fan, Xinqing ^a   Price, Carolyn Mary ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APHIDICOLIN; DNA; DNA POLYMERASE; GUANINE; TELOMERASE; THYMINE;

ARTICLE; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVITY; NONHUMAN; POLYMENOPHOREA; PRIORITY JOURNAL; SYNTHESIS; TELOMERE;

CILIOPHORA; EUPLOTES; POLYMENOPHOREA;

EID: 0030807761     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.8.11.2145     Document Type: Article

References (41)

1. Adams, A.K., and Holm, C. (1996). Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae. Mol. Cell. Biol., 16, 4614-4620.
2. Bacchetti, S. (1996). Telomere dynamics and telomerase activity in cell senescence and cancer. Semin. Cell. Dev. Biol, 7, 31-39.
3. Bednenko, Melek, J.M., Greene, E.C., and Shippen, D.E. (1997). Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation. EMBO J, 16, 2507-2518.
4. Byrnes, J. (1984). Structural and functional properties of DNA polymerase delta from rabbit bone marrow. Mol. Cell. Biochem., 62, 13-24.
5. Carson, M.J., and Hartwell, L. (1985). CDC17: an essential gene that prevents telomere elongation in yeast. Cell, 42, 249-257.
6. Cooper, J.P., Nimmo, E.R., Allshire, R.C., and Cech, T.R. (1997). Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature, 385, 744-747.
7. Fan, Q., and Yao, M.-C. (1996). New telomere formation coupled with site specific chromosome breakage in Tetrahymena thermophila. Mol. Cell. Biol. 16, 1267-1274.
8. Preis, J.S., and Jahn, C.J. (1995). DNA rearrangements in Euplotes crassus coincides with discrete periods of DNA replication during the polytene chromosome stage of macronuclear development. Mol. Cell. Biol., 16, 6488-6495.
9. Greider, C.W. (1996) Telomere-length regulation. Annu. Rev. Biochem., 65, 337-65.
10. Greider, C.W., and Blackburn, E.H. (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell, 43, 405-413.
11. Jahn, C. (1991). The nuclear genomes of hypotrichous ciliates: maintaining the maximum and the minimum of information. J. Protozool., 38, 252-258.
12. Keller, W. (1995). No end yet to messenger RNA 3′ processing. Cell, 81, 829-832.
13. Klobutcher, L.A., Swanton, M.T., Donini, P., and Prescott, D.M. (1981). All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3′ terminus. Proc. Natl. Acad. Sci. U.S.A., 78, 3015-3019.
14. Krauskopf, A., and Blackburn, E.H. (1996). Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats. Nature, 383, 354-357.
15. 1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo. Proc. Natl. Acad. Sci. U.S.A., 93, 13760-13765.
16. Lundblad, V., and Szostak, J.W. (1989). A mutant with a defect in telomere elongation leads to senescence in yeast. Cell, 57, 633-643.
17. Marcand, S., Gibson, E., and Shore, D. (1997). A protein-counting mechanism for telomere length regulation in yeast. Science, 275, 986-990.
18. McEachern, M.J., and Blackburn, E.H. (1995) Runaway telomere elongation caused by telomerase RNA gene mutations. Nature, 376, 403-409.
19. Morrow, D.M., Tagle, D.A., Shiloh, Y., Collins, F.S., and Hieter, P. (1995). TEL1, an S. cerevisiae homolog of the human gene mutated in Ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell, 82, 831-840.
20. Nugent, C.I., Hughes, T.R., Lue, N., and Lundblad, V. (1996). CDC13 is a single-stranded telomere binding protein with a dual role in yeast telomere maintenance. Science, 274, 249-252.
21. Olins, D.E., and Olins, A.L. (1994). The replication band of ciliated protozoa. Int. Rev. Cytol., 153, 137-170.
22. Prescott, D.M. (1994) The DNA of ciliated protozoa. Microbiol. Rev., 58, 233-267.
23. Price, C.M. (1990). Telomere structure in Euplotes crassus: characterization of DNA-protein interactions and isolation of a telomere-binding protein. Mol. Cell. Biol., 10, 3421-3431.
24. Price, C.M. (1997). Synthesis of the telomeric C-strand. Biochemistry, In press.
25. Price, C.M., Adams, A.K., and Vermeesch, J.R. (1994). Accumulation of telomerase RNA and telomere protein transcripts during telomere synthesis in Euplotes. J. Euk. Microbiol., 41, 267-275.
26. Reveal, P.M., Henkels, K.M., and Turchi, J.J. (1997). Synthesis of the mammalian telomere lagging strand in vitro. J. Biol. Chem. 272, 11678-11681.
27. Roth, M., and Prescott, D.M. (1985). DNA intermediates and telomere addition during genome reorganization in Euplotes crassus. Cell, 41, 411-417.
28. Schulz, V.P., and Zakian, V.A. (1994). The Saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation. Cell, 76, 145-156.
29. Sheaff, R., Ilsley, D., and Kuchta, R. (1991). Mechanism of DNA polymerase α inhibition by aphidicolin. Biochemistry, 30, 8590-8597.
30. Singer, M.S., and Gottschling D.E. (1994). TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science, 266, 404-409.
31. Skopp, R., Wang, W., and Price, C.M. (1996). rTP: a candidate telomere protein that is associated with DNA replication. Chromosoma, 105, 82-91.
32. Spadari, S., Sala, F., and Pedrali-Noy, G. (1982). Aphidicolin: a specific inhibitor of nuclear DNA replication in eukaryotes. Trends Biochem. Sci., 7, 29-32.
33. van Steensel, B., and de Lange, T. (1997). Control of telomere length by the human telomeric protein TRF1. Nature, 385, 740-743.
34. Vermeesch, J.R., and Price, C.M. (1994). Telomeric DNA sequence and structure following de novo telomere synthesis in Euplotes crassus. Mol. Cell. Biol., 14, 554-566.
35. Vermeesch, J.R., Williams, D., and Price, C.M. (1993). Telomere processing in Euplotes. Nucleic Acids Res., 21, 5366-5371.
36. Virta-Pearlman, V., Morris, D.K., and Lundblad, V. (1996). EST1 has the properties of a single-strand telomere end-binding protein. Genes Dev., 10, 3094-3104.
37. Wellinger, R.J., Ethier, K., Labrecque, P., and Zakian, Z.A. (1996). Evidence for a new step in telomere maintenance. Cell, 85, 423-433.
38. 1-3 tails occur sequentially in late S phase on a yeast linear plasmid. Mol. Cell. Biol., 13, 4057-4065.
39. Williamson, J.R., Raghuraman, M.K., and Cech, T.R. (1989). Monovalent cation-induced structure of telomeric DNA: the G-quartet model. Cell 59, 871-880.
40. Wright, W.W., Brasiskyte, K., Piatyszek, M.A., and Shay, J.W. (1996). Experimental elongation of telomeres extends the lifespan of immortal × normal cell hybrids. EMBO J., 15, 1734-1741.
41. Zakian, V.A. (1995). Telomeres: function, structure and replication. In Telomeres, ed. E.H. Blackburn and C.W. Greider, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 107-138.