The postprandial state: Mechanisms of glucose intolerance

Diabetic Medicine

Volumn 14, Issue SUPPL. 3, 1997, Pages

  Dinneen, S F ^a  

^a MAYO CLINIC   (United States)

Author keywords

IGT; Insulin resistance; NIDDM; Postprandial state

Indexed keywords

ARTICLE; CARBOHYDRATE METABOLISM; DIABETES MELLITUS; DIABETOGENESIS; GLUCOSE INTOLERANCE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; POSTPRANDIAL STATE;

EID: 0030793208     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1096-9136(199708)14:3+3.3.co;2-l     Document Type: Article

References (34)

1. McGarry JD. What if Minkowski had been ageusic? An alternative angle on diabetes. Science 1992; 258: 766-770.
2. Roden M, Price TB, Perseghin G, Falk Petersen K, Rothman DL, Cline GW, Shulman GI. Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 1996; 97: 2859-2865.
3. WHO Expert Committee on Diabetes Mellitus. Diabetes Mellitus. Second Report. WHO Technical Report Series 646. Geneva: WHO, 1980: 9-14.
4. Kelley D, Mitrakou A, Marsh H, Schwenk F, Benn J, Sonnenberg G, et al. Skeletal muscle glycolysis, oxidation, and storage of an oral glucose load. J Clin Invest 1988; 81: 1563-1571.
5. Fery F, Balasse EO. Glucose metabolism during the starved-to-fed transition in obese patients with NIDDM. Diabetes 1994; 43: 1418-1425.
6. Firth RG, Bell PM, Marsh HM, Hansen I, Rizza RA. Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. J Clin Invest 1986; 77: 1525-1532.
7. Schirra J, Katschinski M, Weidmann C, Schafer T, Wank U, Arnold R, Goke B. Gastric emptying and release of incretin hormones after glucose ingestion in humans. J Clin Invest 1996; 97: 92-103.
8. Stagner JI, Samols E. The vascular order of islet cellular perfusion in the human pancreas. Diabetes 1992; 41: 93-97.
9. Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose fatty-acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963; i: 785-789.
10. Alzaid AA, Dinneen SF, Turk DJ, Caumo A, Cobelli C, Rizza RA. Assessment of insulin action and glucose effectiveness in diabetic and nondiabetic humans. J Clin Invest 1994; 94: 2341-2348.
11. Basu A, Caumo A, Gelisio A, Alzaid A, Cobelli C, Rizza RA. Impaired 'basal' glucose effectiveness in NIDDM: contribution of defects in glucose disappearance and production measured using an optimized minimal model independent protocol. Diabetes 1997; 46: 421-432.
12. Butler PC, Rizza RA. Contribution to postprandial hyperglycemia and effect on initial splanchnic glucose clearance of hepatic glucose cycling in glucose-intolerant or NIDDM patients. Diabetes 1991; 40: 73-81.
13. Mitrakou A, Kelley D, Mokan M, Veneman T, Pangburn T, Reilly J, Gerich J. Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance. N Engl J Med 1992; 326: 22-29.
14. Frank JW, Saslow SB, Camilleri M, Thomforde GM, Dinneen S, Rizza RA. Mechanism of accelerated gastric emptying of liquids and hyperglycemia in patients with Type 2 diabetes mellitus. Gastroenterology 1995; 109: 755-765.
15. McMahon M, Marsh HM, Rizza RA. Effects of basal insulin supplementation on disposition of mixed meal in obese patients with NIDDM. Diabetes 1989; 38: 291-303.
16. Magnusson I, Rothman DL, Jucker B, Cline GW, Shulman RG, Shulman GI. Liver glycogen turnover in fed and fasted humans. Am J Physiol 1994; 266: E796-E803.
17. Dinneen SF, Alzaid A, Schwenk WF, Rizza RA. Postprandial hepatic glycogenolysis persists in diabetic and non-diabetic humans. Clin Res 1994; 42: 117A.
18. Boden G, Ray TK, Smith RH, Owen OE. Carbohydrate oxidation and storage in obese non-insulin-dependent diabetic patients. Effects of improving glycemic control. Diabetes 1983; 32: 982-987.
19. Wright KS, Beck-Nielsen H, Kolterman OG, Mandarino LJ. Decreased activation of skeletal muscle glycogen synthase by mixed-meal ingestion in NIDDM. Diabetes 1988; 37: 436-440.
20. Eriksson J, Franssila-Kallunki A, Ekstrand A, Saloranta C, Widen E, Schalin C, Groop L. Early metabolic detects in persons at increased risk for non-insulin dependent diabetes mellitus. N Engl J Med 1989; 321: 337-343.
21. O'Rahilly S, Turner RC, Matthews DR. Impaired pulsatile secretion of insulin in relatives of patients with non-insulin dependent diabetes. N Engl J Med 1988; 318: 1225-1230.
22. Vague P, Moulin JP. The defective glucose sensitivity of the B cell in non insulin dependent diabetes. Improvement after twenty hours of normoglycemia. Metabolism 1982; 31: 139-142.
23. Janson J, Soeller WC, Roche PC, Nelson RT, Torchia AJ, Krvetter DK, Butler PC. Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide. Proc Natl Acad Sci USA 1996; 93: 7283-7288.
24. Eriksson J, Franssila-Kallunki A, Ekstrand A, Saloranta C, Widen E, Schalin C, Groop L. Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus. N Engl J Med 1989; 321: 337-343.
25. Henriksen JE, Alford F, Handberg A, Vaag A, Ward CM, Kalfas A, Beck-Nielsen H. Increased glucose effectiveness in normoglycemic but insulin-resistant relatives of patients with non-insulin-dependent diabetes mellitus. A novel compensatory mechanism. J Clin Invest 1994; 94: 1196-1204.
26. Basu A, Alzaid A, Dinneen S, Caumo A, Cobelli C, Rizza RA. Effects of a change in the pattern of insulin delivery on carbohydrate tolerance in diabetic and nondiabetic humans in the presence of insulin resistance. J Clin Invest 1996; 97: 2351-2361.
27. Dinneen SF, Alzaid A, Rizza RA. Failure of glucagon suppression contributes to postprandial hyperglycemia in Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1995; 38: 337-343.
28. Bergman RN, Ider YZ, Bowden CR, Cobelli C. Quantitative estimation of insulin sensitivity. Am J Physiol 1979; 236: E667-E677.
29. Welch S, Gebhart SSP, Bergman RN, Phillips LS. Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects. J Clin Endocrinol Metab 1990; 71: 1508-1518.
30. Bjornsson E, Urbanavicius V, Eliasson B, Attvall S, Smith U. Effects of hyperglycaemia on interdigestive gastrointestinal motility in humans. Scand J Gastroenterol 1994; 29: 1096-1104.
31. Chiasson J-L, Josse RC, Hunt JA, Palmason C, Rodger NW, Ross SA, et al. The efficacy of acarbose in the treatment of patients with non-insulin dependent diabetes mellitus. A multicenter controlled clinical trial. Ann Intern Med 1994; 121: 928-935.
32. Rizza R. The role of splanchnic glucose appearance in determining carbohydrate tolerance. Diabetic Med 1996; 13: S23-S27.
33. Nauck M, Stockmann F, Ebert R, Creutzfeldt W. Reduced incretin effect in Type 2 (non-insulin dependent) diabetes. Diabetologia 1986; 29: 46-52.
34. Byrne MM, Coke B. Human studies with glucagon-like-peptide-1 : potential of the gut hormone for clinical use. Diabetic Med 1996; 13: 854-860.