Thrombopoietin is synthesized by bone marrow stromal cells

Blood

Volumn 90, Issue 9, 1997, Pages 3444-3455

  Guerriero, Anastasia ^b   Worford, Lydia ^b   Kent Holland, H ^b   Guo, Gui Rong ^b   Sheehan, Kevin ^b   Waller, Edmund K ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CD38 ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 3; STEM CELL FACTOR; THROMBOPOIETIN;

ADULT; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FETUS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL;

EID: 0030780645     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.9.3444     Document Type: Article

References (43)

1. Moore MA, Owen JT: Stem cell migration in developing myeloid and lymphoid systems. Lancet 8:658, 1967
2. Gordon MY, Clarke D, Atkinson J, Greaves MF: Hemopoietic progenitor cell binding to the stromal microenvironment in vitro. Exp Hematol 18:837, 1990
3. Snodgrass HR, Schmitt RM, Bruyns E: Embryonic stem cells and in vitro hematopoiesis. J Cell Biochem 49:225, 1992
4. Allan TD, Dexter TM: The essential cells of the hematopoietic microenvironment. Exp Hematol 517, 1984
5. Zanjani ED, Pallavicini MG, Ascensao JL, Flake AW, Langlois RG, Reisma M, MacKintosh FR, Stutes D, Harrison MR, Tavassoli M: Engraftment and long-term expansion of human fetal hematopoietic stem cells in sheep following transplantation in utero. J Clin Invest 89:1178, 1992
6. Palacios BA: At day 8-8.5 of mouse development the yolk sac, not the embryo proper, has lymphoid precursor potential in vivo and in vitro. Proc Natl Acad Sci USA 90:6581, 1995
7. Dexter T, Allen TD, Lajtha LG: Conditions controlling the proliferation of hematopoietic cells in vitro. J Cell Physiol 91:335, 1977
8. Verfaillie CM, McCarthy JB, McGlave PB: Differentiation of primitive human multipotent hematopoietic progenitors is accompanied by alterations in their interaction with fibronectin. J Exp Med 174:693, 1991
9. Simmons PJ, Masinovsky B, Longenecker BM, Berenson R, Torok-Storb B, Gallatin WM: Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells. Blood 80:388, 1992
10. Yasumizu C, Toki J, Asou H, Nishino T, Komatsu Y, Ikehara S: Production of hematopoietic stem cell-chemotactic factor by bone marrow stromal cells. Blood 83:964, 1994
11. - bone marrow progenitors during human fetal development. Blood 86:710, 1995
12. Simmons PJ, Torok-Storb B: CD34 expression by stromal precursors in normal human adult bone marrow. Blood 78:2848, 1991
13. Simmons PJ, Torok-Storb B: Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody. Blood 78:55, 1991
14. - fraction of bone marrow. Blood 84:1994
15. Long MW, Robonson JA, Ashcraft EA, Mann KG: Regulation of human bone marrow-derived osteoprogenitor cells by osteogenic growth factors. J Clin Invest 95:881, 1995
16. Terstappen L, Hollander Z, Meiners H, Loken MR: Quantitative comparison of myeloid antigens on five lineages of mature peripheral blood cells. J Leukoc Biol 48:138, 1990
17. Thalmeier K, Meisner P, Reisbach G, Hultner L: Constitutive and modulated cytokine expression in two permanent human bone marrow stromal cell lines. Exp Hematol 24:1, 1996
18. Van Vlasselaer P, Falla N, Snoeck H, Mathieu E: Characterization and purification of osteogenic cells from murine bone marrow by two-color sorting using anti-Sea-1 monoclonal antibody and wheat germ agglutinin. Blood 84:753, 1994
19. Sutherland HJ, Eaves AC, Eaves CJ: Quantitative assays for human hematopoietic progenitor cells, in Bone Marrow Processing and Purging: A Practical Guide. 1991, p 155
20. Nichol JL, Hornkohl AL, Choi ES, Hokom M, Ponting I, Schuening FW, Hunt P: Enrichment and characterization of peripheral blood-derived megakaryocyte progenitors that mature in short-term liquid culture. Stem Cells 12:494, 1994
21. Chomczynski P, Sacchi N: Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
22. Maniatis T: Molecular Cloning: A Laboratory Manual. Plainview, NY, Cold Spring Harbor Laboratory, 1982, p 122
23. Saiki RK, Gelfand DH, Stoffel S: Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239:487, 1988
24. Saiki RK, Scharf S, Faloona F: Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230:1350, 1985
25. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning. A Laboratory Manual. 1989
26. Masamune Y, Richardson C: Strand displacement during deoxyribonucleic acid synthesis at single strand breaks. J Biol Chem 246:2692, 1971
27. Gronthos S, Simmons PJ: The growth factor requirements of STRO-1-positive human bone marrow stromal precursor under serum-deprived conditions in vitro. Blood 85:929, 1995
28. Waller EK, Olweus J, Lund-Johansen FJ, Huang S, Nguyen M, Guo GR, Terstappen L: The "common stem cell" hypothesis re-evaluated: Fetal bone marrow contains separate populations of hematopoietic and stromal progenitors. Blood 85:2422, 1995
29. Kobayashi M, Laver JH, Kato T, Miyazaki H, Ogawa M: Thrombopoietin supports proliferation of human primitive hematopoietic cells in synergy with Steel factor and/or IL-3. Blood 88:429, 1996
30. Healy L, May G, Gale K, Grosveld F, Greaves M, Enver T: The stem cell antigen CD34 functions as a regulator of hemopoietic cell adhesion, Proc Natl Acad Sci USA 92:12240, 1995
31. Maximow AA: Relation of blood cells to connective tissues and endothelium. Physiol Rev 4:533, 1924
32. Papayannopoulou T, Nakamoto B: Peripheralization of hematopoietic progenitors in primates treated with anti-VLA4 integrin. Proc Natl Acad Sci USA 90:9374, 1993
33. Hsun K, Yuji Y, Kenneth K, Makio O: Thrombopoietin, the ligand for the Mpl receptor, synergizes with Steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice. Blood 87:4544, 1996
34. Sitnicka E, Lin N, Priestley GV, Fox N, Broudy VC, Wolf NS, Kaushansky K: The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells. Blood 87:4998, 1996
35. Kaushansky K, Broudy VC, Grossmann A, Humes J, Lin N, Ren HP, Bailey MC, Papayannopoulou T, Forstrom JW, Sprugel KH: Thrombopoietin expands erythro995id progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive,therapy. J Clin Invest 96:1683, 1995
36. Era T, Takahashi T, Sakai K, Kawamura K, Nukano T: Thrombopoietin enhances proliferation and differentiation of murine yolk sac erythroid progenitors. Blood 89:1207, 1997
37. + subpopulation of rat megakaryocyte progenitor cells exhibits high responsiveness to human thrombopoietin. Exp Hematol 24:1209, 1996
38. McCarty JM, Sprugel KH, Fox Ne, Sabath DE, Kaushansky K: Murine thrombopoietin mRNA levels are modulated by platelet count. Blood 86:3668, 1995
39. Sungaran R, Markovic B, Chong BB: Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization. Blood 89:101, 1997
40. - cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor. Blood 77:2316, 1991
41. Levene RB, Williams NT, Lamaziere J, Rabillino EM: Human megakaryocytes. IV. Growth and characterization of clonable megakaryocyte progenitors in agar. Exp Hematol 15:181, 1987
42. Avraham H, Scadden D, Chi S, Broudy V, Zsebo KM, Groopman JE: Interaction of human bone marrow fibroblasts with megakaryocytes: Role of the c-kit ligand. Blood 80:1679, 1992
43. Miyazaki H: Cloning of thrombopoietin and its therapeutic potential. Cancer Chemother Pharmacol 38:S74, 1996 (suppl)