-
1
-
-
0028152333
-
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
-
Marshall CJ. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Genet Dev. 4:1994;82-89.
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 82-89
-
-
Marshall, C.J.1
-
2
-
-
0028926263
-
Parallel signal-processing among mammalian MAPKs
-
Cano E, Mahadevan LC. Parallel signal-processing among mammalian MAPKs. Trends Biochem Sci. 20:1995;117-122.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 117-122
-
-
Cano, E.1
Mahadevan, L.C.2
-
3
-
-
0028170820
-
Small GTP-binding proteins and the regulation of the actin cytoskeleton
-
Hall A. Small GTP-binding proteins and the regulation of the actin cytoskeleton. Ann Rev Cell Biol. 10:1994;31-54.
-
(1994)
Ann Rev Cell Biol
, vol.10
, pp. 31-54
-
-
Hall, A.1
-
4
-
-
0028221043
-
Signaling pathways initiated by receptor protein-tyrosine kinases in Drosophila
-
Perrimon N. Signaling pathways initiated by receptor protein-tyrosine kinases in Drosophila. Curr Opin Cell Biol. 6:1994;260-266.
-
(1994)
Curr Opin Cell Biol
, vol.6
, pp. 260-266
-
-
Perrimon, N.1
-
5
-
-
0029834756
-
The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye
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of outstanding interest. This paper and [6] report the cloning and characterization of the Drosophila JNK hormologue and show that DJNK is encoded by basket. The authors shows that the product of basket behaves biochemically as a JNK and that its activity is boosted in vivo after exposure of live animals to UV irradiation, basket shows maternal contribution and disrupts the initiation of dorsal closure, basket, as hep [7], regulates the expression of puckered - a putative regulator of JNK signal - expressed in the dorsal-most epidermal cells (Martin-Blanco, unpublished data).
-
Riesgo-Escovar JR, Jenni M, Fritz A, Hafen E. The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. of outstanding interest Genes Dev. 10:1996;2759-2768 This paper and [6] report the cloning and characterization of the Drosophila JNK hormologue and show that DJNK is encoded by basket. The authors shows that the product of basket behaves biochemically as a JNK and that its activity is boosted in vivo after exposure of live animals to UV irradiation, basket shows maternal contribution and disrupts the initiation of dorsal closure, basket, as hep [7], regulates the expression of puckered - a putative regulator of JNK signal - expressed in the dorsal-most epidermal cells (Martin-Blanco, unpublished data).
-
(1996)
Genes Dev
, vol.10
, pp. 2759-2768
-
-
Riesgo-Escovar, J.R.1
Jenni, M.2
Fritz, A.3
Hafen, E.4
-
6
-
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0029824847
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A JNK signal-transduction pathway that mediates morphogenesis and an immune-response in Drosophila
-
of outstanding interest. See annotation [5]. Besides the cloning of the DJNK, the authors of this paper report that Basket is a target of the DJNKK Hep and analyze its substrate specificity towards DJun. Apart from the DJNK function in dorsal closure, it also explores the role of this pathway in the insect immune response. It reports a strong correlation between the activation of DJNK by LPS and the expression of the antibacterial peptides cecropin and diptericin.
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Sluss HK, Han ZQ, Barrett T, Davis RJ, Ip YT. A JNK signal-transduction pathway that mediates morphogenesis and an immune-response in Drosophila. of outstanding interest Genes Dev. 10:1996;2745-2758 See annotation [5]. Besides the cloning of the DJNK, the authors of this paper report that Basket is a target of the DJNKK Hep and analyze its substrate specificity towards DJun. Apart from the DJNK function in dorsal closure, it also explores the role of this pathway in the insect immune response. It reports a strong correlation between the activation of DJNK by LPS and the expression of the antibacterial peptides cecropin and diptericin.
-
(1996)
Genes Dev
, vol.10
, pp. 2745-2758
-
-
Sluss, H.K.1
Han, Z.Q.2
Barrett, T.3
Davis, R.J.4
Ip, Y.T.5
-
7
-
-
0028875388
-
Hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement
-
Glise B, Bourbon H, Noselli S. Hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement. Cell. 83:1995;451-461.
-
(1995)
Cell
, vol.83
, pp. 451-461
-
-
Glise, B.1
Bourbon, H.2
Noselli, S.3
-
8
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0030917227
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The role of RhoA in tissue polarity and frizzled signalling
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of special interest. This paper describes an interesting genetic interaction between the frizzed signal transduction pathway and the small GTPase RhoA in the establishment of planar polarity in epidermal structures. RhoA mutants display dorsal closure phenotypes reminiscent of those of mutants in members of the DJNK pathway.
-
Stutt DI, Weber U, Mlodzik M. The role of RhoA in tissue polarity and frizzled signalling. of special interest Nature. 387:1997;292-295 This paper describes an interesting genetic interaction between the frizzed signal transduction pathway and the small GTPase RhoA in the establishment of planar polarity in epidermal structures. RhoA mutants display dorsal closure phenotypes reminiscent of those of mutants in members of the DJNK pathway.
-
(1997)
Nature
, vol.387
, pp. 292-295
-
-
Stutt, D.I.1
Weber, U.2
Mlodzik, M.3
-
9
-
-
0028947261
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Dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell-shape changes in Drosophila
-
Harden N, Loh NY, Chia W, Lim L. Dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell-shape changes in Drosophila. Development. 121:1995;903-914.
-
(1995)
Development
, vol.121
, pp. 903-914
-
-
Harden, N.1
Loh, N.Y.2
Chia, W.3
Lim, L.4
-
10
-
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0030793160
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Coupling of Jun amino-terminal kinase and Decapentaplegic signaling pathways in Drosophila morphogenesis
-
of outstanding interest. This paper, along with [18,19], shows that dpp expression in the dorsal-most epidermal cells depends on DJNK signalling activity. It also links the small GTPases DCdc42 and DRac1 to this function by analyzing the effects of the overexpression of activated and dominant negative forms of these proteins. It also shows that puckered, a gene expressed in the leading edge, could have some negative effects on the activity of the pathway (Martin-Blanco, unpublished data).
-
Glise B, Noselli S. Coupling of Jun amino-terminal kinase and Decapentaplegic signaling pathways in Drosophila morphogenesis. of outstanding interest Genes Dev. 11:1997;1738-1747 This paper, along with [18,19], shows that dpp expression in the dorsal-most epidermal cells depends on DJNK signalling activity. It also links the small GTPases DCdc42 and DRac1 to this function by analyzing the effects of the overexpression of activated and dominant negative forms of these proteins. It also shows that puckered, a gene expressed in the leading edge, could have some negative effects on the activity of the pathway (Martin-Blanco, unpublished data).
-
(1997)
Genes Dev
, vol.11
, pp. 1738-1747
-
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Glise, B.1
Noselli, S.2
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11
-
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0030940549
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Isolation of mutations in the Drosophila homologues of the human neurofibromatosis 2 and yeast CDC42 genes using a simple and efficient reverse-genetic method
-
Fehon RG, Oren T, Lajeunesse DR, Melby TE, McCartney BM. Isolation of mutations in the Drosophila homologues of the human neurofibromatosis 2 and yeast CDC42 genes using a simple and efficient reverse-genetic method. Genetics. 146:1997;245-252.
-
(1997)
Genetics
, vol.146
, pp. 245-252
-
-
Fehon, R.G.1
Oren, T.2
Lajeunesse, D.R.3
Melby, T.E.4
McCartney, B.M.5
-
12
-
-
0028078824
-
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
-
Manser E, Leung T, Salihuddin H, Zhao Z-S, Lim L. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature. 367:1994;40-46.
-
(1994)
Nature
, vol.367
, pp. 40-46
-
-
Manser, E.1
Leung, T.2
Salihuddin, H.3
Zhao, Z.-S.4
Lim, L.5
-
13
-
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0029963547
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A Drosophila homolog of the Rac-activated and CDC42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures
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of special interest. DPAK, a Drosophila homologue of the serine/threonine kinase p65PAK, is found associated with focal adhesions and Cdc42- and Rac-induced focal complexes. Leading-edge epidermal cells, which express DPAK, undergo transient losses of cytoskeletal structures during dorsal closure.
-
Harden N, Lee J, Loh NY, Ong YM, Tan I, Leung T, Manser E, Lim L. A Drosophila homolog of the Rac-activated and CDC42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures. of special interest Mols Cell Biol. 16:1996;1896-1908 DPAK, a Drosophila homologue of the serine/threonine kinase p65PAK, is found associated with focal adhesions and Cdc42- and Rac-induced focal complexes. Leading-edge epidermal cells, which express DPAK, undergo transient losses of cytoskeletal structures during dorsal closure.
-
(1996)
Mols Cell Biol
, vol.16
, pp. 1896-1908
-
-
Harden, N.1
Lee, J.2
Loh, N.Y.3
Ong, Y.M.4
Tan, I.5
Leung, T.6
Manser, E.7
Lim, L.8
-
14
-
-
12044251332
-
Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function
-
Young PE, Richman AM, Ketchum AS, Kiehart DP. Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function. Genes Dev. 7:1993;29-41.
-
(1993)
Genes Dev
, vol.7
, pp. 29-41
-
-
Young, P.E.1
Richman, A.M.2
Ketchum, A.S.3
Kiehart, D.P.4
-
15
-
-
0027884890
-
Puckered, a gene involved in position-specific cell differentiation in the dorsal epidermis
-
Ring JM, Matinez-Arias A. puckered, a gene involved in position-specific cell differentiation in the dorsal epidermis. Development. 119:1993;251-259.
-
(1993)
Development
, vol.119
, pp. 251-259
-
-
Ring, J.M.1
Matinez-Arias, A.2
-
16
-
-
0000480639
-
Development and patterning of the larval epidermis of Drosophila
-
M. Bate, Martinez-Arias A. Cold Spring Harbor NY: Cold Spring Harbor Laboratory Press
-
Martinez-Arias A. Development and patterning of the larval epidermis of Drosophila. Bate M, Martinez-Arias A. The Development of Drosophila melanogaster. 1993;517-608 Cold Spring Harbor Laboratory Press, Cold Spring Harbor NY.
-
(1993)
The Development of Drosophila Melanogaster
, pp. 517-608
-
-
Martinez-Arias, A.1
-
17
-
-
0008125299
-
Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster I. Zygotic loci on the second chromosome
-
Nüsslein-Volhard C, Wieschaus E, Kluding M. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster I. Zygotic loci on the second chromosome. Rouxs Arch Dev Biol. 193:1984;235-271.
-
(1984)
Rouxs Arch Dev Biol
, vol.193
, pp. 235-271
-
-
Nüsslein-Volhard, C.1
Wieschaus, E.2
Kluding, M.3
-
18
-
-
0030797351
-
Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure
-
of outstanding interest. This paper and [19,20] describe the isolation of mutants for Drosophila DJun. It reports genetic evidence that DJun is a target in the DJNK pathway during dorsal closure and that the expression of dpp in the leading edge is regulated by DJun and DJNK activity. Mutants in tkv, a dpp type I receptor, show elongation of the dorsal-most cells of the epidermis but not in lateral cells, suggesting that dpp acts as a paracrine signal in the lateral epidermis. Furthermore, this paper shows that the gene anterior open, a transcriptional repressor of dpp, is inhibited by DJNK signalling and is required for dorsal closure. Finally, after studying mitotic clones, the authors suggest that Djun is not required for cell fate determination in the developing eye.
-
Riesgo-Escovar JR, Hafen E. Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure. of outstanding interest Genes Dev. 11:1997;1717-1727 This paper and [19,20] describe the isolation of mutants for Drosophila DJun. It reports genetic evidence that DJun is a target in the DJNK pathway during dorsal closure and that the expression of dpp in the leading edge is regulated by DJun and DJNK activity. Mutants in tkv, a dpp type I receptor, show elongation of the dorsal-most cells of the epidermis but not in lateral cells, suggesting that dpp acts as a paracrine signal in the lateral epidermis. Furthermore, this paper shows that the gene anterior open, a transcriptional repressor of dpp, is inhibited by DJNK signalling and is required for dorsal closure. Finally, after studying mitotic clones, the authors suggest that Djun is not required for cell fate determination in the developing eye.
-
(1997)
Genes Dev
, vol.11
, pp. 1717-1727
-
-
Riesgo-Escovar, J.R.1
Hafen, E.2
-
19
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0030742943
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Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway in regulating epithelial cell sheet movement
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of outstanding interest. See annotation [18]. The authors of this paper describe that the disruption of the initiation of dorsal closure in Djun mutants involves alterations in the distribution of phosphotyrosine, actin, and myosin. They also report that the ectopic expression of an activated form of Tkv suppresses the dorsal hole phenotype of Djun mutants, suggesting that the dpp signal transduction pathway acts downstream of DJun. They point out that mitotic clones of Djun have no effect on eye development and that Djun mutations in heterozygosity do not suppress the rough-eye phenotype induced by the activation of the ERK pathway.
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Hou XS, Goldstein ES, Perrimon N. Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway in regulating epithelial cell sheet movement. of outstanding interest Genes Dev. 11:1997;1728-1737 See annotation [18]. The authors of this paper describe that the disruption of the initiation of dorsal closure in Djun mutants involves alterations in the distribution of phosphotyrosine, actin, and myosin. They also report that the ectopic expression of an activated form of Tkv suppresses the dorsal hole phenotype of Djun mutants, suggesting that the dpp signal transduction pathway acts downstream of DJun. They point out that mitotic clones of Djun have no effect on eye development and that Djun mutations in heterozygosity do not suppress the rough-eye phenotype induced by the activation of the ERK pathway.
-
(1997)
Genes Dev
, vol.11
, pp. 1728-1737
-
-
Hou, X.S.1
Goldstein, E.S.2
Perrimon, N.3
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20
-
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0030857388
-
Jun in Drosophila development: Redundant and non redundant functions and regulation by two MAPK signal transduction pathways
-
of outstanding interest. See annotation [18]. A description that Djun null mutations and the expression of dominant negative forms of Djun disrupt dorsal closure. Experiments using conditional and sensitized situations suggest a redundant function for Djun in the eye, interacting genetically with the ERK signal transduction pathway.
-
Kockel S, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D. Jun in Drosophila development: redundant and non redundant functions and regulation by two MAPK signal transduction pathways. of outstanding interest Genes Dev. 11:1997;1748-1758 See annotation [18]. A description that Djun null mutations and the expression of dominant negative forms of Djun disrupt dorsal closure. Experiments using conditional and sensitized situations suggest a redundant function for Djun in the eye, interacting genetically with the ERK signal transduction pathway.
-
(1997)
Genes Dev
, vol.11
, pp. 1748-1758
-
-
Kockel, S.1
Zeitlinger, J.2
Staszewski, L.M.3
Mlodzik, M.4
Bohmann, D.5
-
21
-
-
0026723089
-
Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ets domain protein
-
Lai Z-C, Rubin G. Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ets domain protein. Cell. 70:1992;609-620.
-
(1992)
Cell
, vol.70
, pp. 609-620
-
-
Lai, Z.-C.1
Rubin, G.2
-
22
-
-
0027984806
-
The ETS domain protein Pointed-P2 is a target of MAP kinasse in the Sevenless signal transduction pathway
-
Brunner D, Dücker K, Oellers N, Hafen E, Scholz H, Klämbt C. The ETS domain protein Pointed-P2 is a target of MAP kinasse in the Sevenless signal transduction pathway. Nature. 370:1994;386-389.
-
(1994)
Nature
, vol.370
, pp. 386-389
-
-
Brunner, D.1
Dücker, K.2
Oellers, N.3
Hafen, E.4
Scholz, H.5
Klämbt, C.6
-
23
-
-
0028239896
-
The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway
-
O'Neill EM, Rebay I, Tjian R, Rubin GM. The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell. 78:1994;137-147.
-
(1994)
Cell
, vol.78
, pp. 137-147
-
-
O'Neill, E.M.1
Rebay, I.2
Tjian, R.3
Rubin, G.M.4
-
24
-
-
0028132086
-
Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF-β homologs during Drosophila embryogenesis
-
Affolter MD, Nellen D, Nussbaumer U, Basler K. Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF-β homologs during Drosophila embryogenesis. Development. 120:1994;3105-3117.
-
(1994)
Development
, vol.120
, pp. 3105-3117
-
-
Affolter, M.D.1
Nellen, D.2
Nussbaumer, U.3
Basler, K.4
-
25
-
-
0030054647
-
The tumor suppressor gene, lethal(2)giant larvae (l(2)gl), is required for cell shape change of epithelial cells during Drosophila development
-
ts3 mutant embryos are affected in dorsal closure. This phenotype is accompanied by an arrest of the normal cell shape changes in the lateral epidermis. The paper discusses the putative role of l(2)gl linking small GTPases signalling and cytoskeletal changes.
-
ts3 mutant embryos are affected in dorsal closure. This phenotype is accompanied by an arrest of the normal cell shape changes in the lateral epidermis. The paper discusses the putative role of l(2)gl linking small GTPases signalling and cytoskeletal changes.
-
(1996)
Development
, vol.122
, pp. 2283-2294
-
-
Manfruelli, P.1
Arquier, N.2
Hanratty, W.P.3
Sémériva, M.4
-
26
-
-
0027173445
-
The l(2)gl homologue of Drosophila pseudoobscura supresses tumorigenicity in transgenic Drosophila melanogaster
-
Török I, Hartenstein K, Kalmes A, Schmitt R, Strand D, Mechler BM. The l(2)gl homologue of Drosophila pseudoobscura supresses tumorigenicity in transgenic Drosophila melanogaster. Oncogene. 8:1993;1537-1549.
-
(1993)
Oncogene
, vol.8
, pp. 1537-1549
-
-
Török, I.1
Hartenstein, K.2
Kalmes, A.3
Schmitt, R.4
Strand, D.5
Mechler, B.M.6
-
27
-
-
0028061614
-
The Drosophila lethal(2)giant larvae tumor supressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain
-
Strand D, Jakobs R, Merdes G, Neumann B, Kalmes A, Heid HW, Husmann I, Mechler BM. The Drosophila lethal(2)giant larvae tumor supressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain. J Cell Biol. 127:1994;1361-1373.
-
(1994)
J Cell Biol
, vol.127
, pp. 1361-1373
-
-
Strand, D.1
Jakobs, R.2
Merdes, G.3
Neumann, B.4
Kalmes, A.5
Heid, H.W.6
Husmann, I.7
Mechler, B.M.8
-
28
-
-
0023695794
-
Regulation of Actin microfilament integrity in living nonmuscle cells by the cAMP dependent protein kinase and the myosin light chain kinase
-
Lamb NJD, Fernandez A, Conti MA, Adelstein R, Glass DB, Welch WJ, Feramisco JR. Regulation of Actin microfilament integrity in living nonmuscle cells by the cAMP dependent protein kinase and the myosin light chain kinase. J Cell Biol. 106:1988;1955-1971.
-
(1988)
J Cell Biol
, vol.106
, pp. 1955-1971
-
-
Lamb, N.J.D.1
Fernandez, A.2
Conti, M.A.3
Adelstein, R.4
Glass, D.B.5
Welch, W.J.6
Feramisco, J.R.7
-
29
-
-
0027930236
-
Drosophila Jun mediates Ras-dependent photoreceptor determination
-
Bohmann D, Ellis MC, Staszewski LM, Mlodzik M. Drosophila Jun mediates Ras-dependent photoreceptor determination. Cell. 78:1994;973-986.
-
(1994)
Cell
, vol.78
, pp. 973-986
-
-
Bohmann, D.1
Ellis, M.C.2
Staszewski, L.M.3
Mlodzik, M.4
-
30
-
-
0028784204
-
Jun cooperates with the ETS domain protein Pointed to induce photoreceptor R7 fate in the Drosophila eye
-
Treier M, Bohmann D, Mlodzik M. Jun cooperates with the ETS domain protein Pointed to induce photoreceptor R7 fate in the Drosophila eye. Cell. 83:1995;753-760.
-
(1995)
Cell
, vol.83
, pp. 753-760
-
-
Treier, M.1
Bohmann, D.2
Mlodzik, M.3
-
31
-
-
0029738257
-
Phosphorylation of Drosophila Jun by the MAP kinase rolled regulates photoreceptor differentiation
-
Peverali FA, Isaksson A, Papavassiliou AG, Plastina P, Staszewski LM, Mlodzik M, Bohmann D. Phosphorylation of Drosophila Jun by the MAP kinase rolled regulates photoreceptor differentiation. EMBO J. 15:1996;3943-3950.
-
(1996)
EMBO J
, vol.15
, pp. 3943-3950
-
-
Peverali, F.A.1
Isaksson, A.2
Papavassiliou, A.G.3
Plastina, P.4
Staszewski, L.M.5
Mlodzik, M.6
Bohmann, D.7
-
32
-
-
0028229012
-
The stress-activated protein kinase subfamily of c-Jun kinases
-
Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR. The stress-activated protein kinase subfamily of c-Jun kinases. Nature. 369:1994;156-160.
-
(1994)
Nature
, vol.369
, pp. 156-160
-
-
Kyriakis, J.M.1
Banerjee, P.2
Nikolakaki, E.3
Dai, T.4
Rubie, E.A.5
Ahmad, M.F.6
Avruch, J.7
Woodgett, J.R.8
-
33
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
Dérijard B, Hibi M, Wu I-H, Barrett T, Su B, Deng T, Marin M, Davis RJ. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell. 76:1994;1025-1037.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Dérijard, B.1
Hibi, M.2
Wu, I.-H.3
Barrett, T.4
Su, B.5
Deng, T.6
Marin, M.7
Davis, R.J.8
-
34
-
-
0029947996
-
MEK kinase is involved in tumor necrosis factor α-induced NF-κB activation and degradation of IκB-α
-
Hirano M, Osada S, Aoki T, Hirai S, Hosaka M, Inoue J, Ohno S. MEK kinase is involved in tumor necrosis factor α-induced NF-κB activation and degradation of IκB-α J Biol Chem. 271:1996;13234-13238.
-
(1996)
J Biol Chem
, vol.271
, pp. 13234-13238
-
-
Hirano, M.1
Osada, S.2
Aoki, T.3
Hirai, S.4
Hosaka, M.5
Inoue, J.6
Ohno, S.7
-
35
-
-
0028086441
-
Distinct morphogenetic functions of similar small GTPases: Drosophila DRac1 is involved in axon outgrowth and myoblast fusion
-
Luo L, Liao J, Jan LY, Jan YN. Distinct morphogenetic functions of similar small GTPases: Drosophila DRac1 is involved in axon outgrowth and myoblast fusion. Genes Dev. 8:1994;1787-1802.
-
(1994)
Genes Dev
, vol.8
, pp. 1787-1802
-
-
Luo, L.1
Liao, J.2
Jan, L.Y.3
Jan, Y.N.4
-
36
-
-
0029097186
-
CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium
-
Eaton S, Auvinen P, Luo LQ, Jan YN, Simons K. CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium. J Cell Biol. 131:1995;151-164.
-
(1995)
J Cell Biol
, vol.131
, pp. 151-164
-
-
Eaton, S.1
Auvinen, P.2
Luo, L.Q.3
Jan, Y.N.4
Simons, K.5
-
37
-
-
0030458493
-
Roles for Rac1 and CDC42 in planar polarization and hair outgrowth in the wing of Drosophila
-
of special interest. By interfering with normal function by overexpression of dominant negative products, the authors of this paper describe the role of DRac1 in the organization of junctional actin and the microtubule network associated with the junctional region in wing cells. They also describe the requirement for Cdc42 activity for localized actin polymerization during hair formation.
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Eaton S, Wept R, Simons K. Roles for Rac1 and CDC42 in planar polarization and hair outgrowth in the wing of Drosophila. of special interest J Cell Biol. 135:1996;1277-1289 By interfering with normal function by overexpression of dominant negative products, the authors of this paper describe the role of DRac1 in the organization of junctional actin and the microtubule network associated with the junctional region in wing cells. They also describe the requirement for Cdc42 activity for localized actin polymerization during hair formation.
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(1996)
J Cell Biol
, vol.135
, pp. 1277-1289
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Eaton, S.1
Wept, R.2
Simons, K.3
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