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Volumn 283, Issue 1, 1997, Pages 375-383

The novel calcium sensitizer levosimendan activates the ATP-sensitive K+ channel in rat ventricular cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; GLIBENCLAMIDE; LEVOSIMENDAN; POTASSIUM CHANNEL; PYROPHOSPHATE;

EID: 0030771922     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (180)

References (45)
  • 1
    • 0025977317 scopus 로고
    • Cellular distribution of phosphodiesterase isoforms in rat cardiac tissue
    • BODE, D. C., KANTKR, J. R. AND BRUNTON, L. L.: Cellular distribution of phosphodiesterase isoforms in rat cardiac tissue. Circ. Res. 68: 1070-1079, 1991.
    • (1991) Circ. Res. , vol.68 , pp. 1070-1079
    • Bode, D.C.1    Kantkr, J.R.2    Brunton, L.L.3
  • 5
  • 6
    • 0029097331 scopus 로고
    • Systemic and coronary hemodynamic actions and left ventricular functional effects of levosimendan in conscious dogs
    • HARKIN, C. P., PAGEL, P. S., TESSMER, J. P. AND WARLTIER, D. C.: Systemic and coronary hemodynamic actions and left ventricular functional effects of levosimendan in conscious dogs. J. Cardiovasc. Pharmacol. 26: 179-188, 1995.
    • (1995) J. Cardiovasc. Pharmacol. , vol.26 , pp. 179-188
    • Harkin, C.P.1    Pagel, P.S.2    Tessmer, J.P.3    Warltier, D.C.4
  • 7
    • 0029081730 scopus 로고
    • Activation of ATP-sensitive potassium channels: A novel pharmacological approach to myocardial protection?
    • HEARSE, D. J.: Activation of ATP-sensitive potassium channels: a novel pharmacological approach to myocardial protection? Cardiovasc. Res. 30: 1-17, 1995.
    • (1995) Cardiovasc. Res. , vol.30 , pp. 1-17
    • Hearse, D.J.1
  • 8
    • 85047677215 scopus 로고
    • Do potassium channel openers compete with ATP to activate ATP sensitive potassium channels?
    • HENRY, P., ESCANDE, D.: Do potassium channel openers compete with ATP to activate ATP sensitive potassium channels? Cardiovasc. Res. 28: 754-759, 1994.
    • (1994) Cardiovasc. Res. , vol.28 , pp. 754-759
    • Henry, P.1    Escande, D.2
  • 9
    • 0020645239 scopus 로고
    • Modulation by intracellular ATP and cyclic AMP of the slow inward current in isolated single ventricular cells of the guineapig
    • Lond.
    • IRISAWA, H. AND KOKUBUN, S.: Modulation by intracellular ATP and cyclic AMP of the slow inward current in isolated single ventricular cells of the guineapig. J. Physiol. (Lond.) 338: 321-337, 1983.
    • (1983) J. Physiol. , vol.338 , pp. 321-337
    • Irisawa, H.1    Kokubun, S.2
  • 10
    • 0028287396 scopus 로고
    • Intracellular acidification and ADP enhance nicorandil induction of ATP sensitive potassium channel current in cardiomyocytes
    • JAHANGIR, A., TERZIC, A. AND KURACHI, Y.: Intracellular acidification and ADP enhance nicorandil induction of ATP sensitive potassium channel current in cardiomyocytes. Cardiovasc. Res. 28: 831-835, 1994.
    • (1994) Cardiovasc. Res. , vol.28 , pp. 831-835
    • Jahangir, A.1    Terzic, A.2    Kurachi, Y.3
  • 11
    • 0024325322 scopus 로고
    • Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction
    • JANSE, M. J AND WIT, A. L.: Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction. Physiol. Rev. 69: 1049-1169, 1989.
    • (1989) Physiol. Rev. , vol.69 , pp. 1049-1169
    • Janse, M.J.1    Wit, A.L.2
  • 12
    • 0021892605 scopus 로고
    • Properties of adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells
    • Lond.
    • KAKEI, M., NOMA, A. AND SHIBASAKI, T.: Properties of adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells. J. Physiol. (Lond.) 363: 441-462, 1985.
    • (1985) J. Physiol. , vol.363 , pp. 441-462
    • Kakei, M.1    Noma, A.2    Shibasaki, T.3
  • 14
    • 0027451993 scopus 로고
    • Cardiotonic actions of selective phosphodifsterase inhibitors in rat isolated ventricular cardiomyocytes
    • KELSO, E. J., MCDERMOTT, B. J. AND SILKE, B.: Cardiotonic actions of selective phosphodifsterase inhibitors in rat isolated ventricular cardiomyocytes. Br. J. Pharmacol. 110: 1387-1394, 1993.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 1387-1394
    • Kelso, E.J.1    Mcdermott, B.J.2    Silke, B.3
  • 15
    • 0027340688 scopus 로고
    • ATP, channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic β-cells
    • Lond.
    • ATP, channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic β-cells. J. Physiol. (Lond.) 463: 349-365, 1993.
    • (1993) J. Physiol. , vol.463 , pp. 349-365
    • Larrson, O.1    Ammala, C.2    Bokvist, K.3    Fredholm, B.4    Rorsman, P.5
  • 16
    • 0029558280 scopus 로고
    • Dose-range study of a new calcium sensitizer, levosimendan, in patients with left ventricular dysfunction
    • LILLEBERG, J., SUNDBKRG, S. AND NIEMINEN, M. S.: Dose-range study of a new calcium sensitizer, levosimendan, in patients with left ventricular dysfunction. J. Cardiovasc. Pharmacol. 26 (Suppl. 1): S63-S69, 1995.
    • (1995) J. Cardiovasc. Pharmacol. , vol.26 , Issue.1 SUPPL.
    • Lilleberg, J.1    Sundbkrg, S.2    Nieminen, M.S.3
  • 17
    • 0025027643 scopus 로고
    • Interrelation between puiacidil and intracellular ATP concentrations on activation of the ATP-sensitive K current in guinea pig ventricular myocytes
    • NAKAYAMA. K., FAX, Z., MARUMO, F. AND HIRAOKA, M.: Interrelation between puiacidil and intracellular ATP concentrations on activation of the ATP-sensitive K current in guinea pig ventricular myocytes. Circ. Res. 67: 1124-1133, 1990.
    • (1990) Circ. Res. , vol.67 , pp. 1124-1133
    • Nakayama, K.1    Fax, Z.2    Marumo, F.3    Hiraoka, M.4
  • 18
    • 0029609859 scopus 로고
    • Will calcium sensitizers play a role in the treatment of heart failure?
    • NIELSEN-KUDSK, J. E. AND ALDERSHVILE, J.: Will calcium sensitizers play a role in the treatment of heart failure? J. Cardiovasc. Pharmacol. 26 (Suppl. 1) S77-S84, 1995.
    • (1995) J. Cardiovasc. Pharmacol. , vol.26 , Issue.1 SUPPL.
    • Nielsen-Kudsk, J.E.1    Aldershvile, J.2
  • 19
    • 0345669398 scopus 로고
    • Modulation of single slow (L-typel) calcium channels by intracellular ATP in vascular smooth muscle cells
    • OHYA, Y. AND SPERELAKIS, N.: Modulation of single slow (L-typel) calcium channels by intracellular ATP in vascular smooth muscle cells. Pflugers. Arch. 414: 257-264, 1989.
    • (1989) Pflugers. Arch. , vol.414 , pp. 257-264
    • Ohya, Y.1    Sperelakis, N.2
  • 20
    • 0026725596 scopus 로고
    • Phosphorylation-independent modulation of L-type calcium channels by magnesium-nucleotide complexes
    • O'ROURKE, B., BACKX, P. H. AND MARBAN, E.: Phosphorylation-independent modulation of L-type calcium channels by magnesium-nucleotide complexes. Science 257: 245-248, 1992.
    • (1992) Science , vol.257 , pp. 245-248
    • O'Rourke, B.1    Backx, P.H.2    Marban, E.3
  • 21
    • 0023723794 scopus 로고
    • Vasodilator and inotropic drugs for the treatment of chronic heart failure: Distinguishing hype from hope
    • PACKER, M.: Vasodilator and inotropic drugs for the treatment of chronic heart failure: distinguishing hype from hope. J. Am. Coll. Cardiol. 12: 1299-1317, 1988.
    • (1988) J. Am. Coll. Cardiol. , vol.12 , pp. 1299-1317
    • Packer, M.1
  • 23
    • 0028826965 scopus 로고
    • Zatebradine, a specific bradycardic agent, alters the hemodynamic and left ventricular mechanical actions of levosimendan, a new myofilament calcium sensitizer, in conscious dogs
    • PAGEL, P. S., HARKIN, C. P., HETTRICK, D. A. AND WARLTIER, D. C.: Zatebradine, a specific bradycardic agent, alters the hemodynamic and left ventricular mechanical actions of levosimendan, a new myofilament calcium sensitizer, in conscious dogs. J. Pharmacol. Exp. Ther. 275: 127-135, 1995.
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 127-135
    • Pagel, P.S.1    Harkin, C.P.2    Hettrick, D.A.3    Warltier, D.C.4
  • 25
    • 0029942933 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases and vascular smooth muscle
    • POLSON, J. B.: Cyclic nucleotide phosphodiesterases and vascular smooth muscle. Annu. Rev. Pharmacol. Toxicol. 36: 403-427, 1996.
    • (1996) Annu. Rev. Pharmacol. Toxicol. , vol.36 , pp. 403-427
    • Polson, J.B.1
  • 26
    • 0025224090 scopus 로고
    • + channel activity and contractile behavior in mammalian ventricle by the potassium channel openers cromakalim and RP49356
    • + channel activity and contractile behavior in mammalian ventricle by the potassium channel openers cromakalim and RP49356. J. Pharmacol. Exp. Ther. 255: 429-435, 1990.
    • (1990) J. Pharmacol. Exp. Ther. , vol.255 , pp. 429-435
    • Ripoll, C.1    Lederer, W.J.2    Nichols, C.G.3
  • 27
    • 0028245011 scopus 로고
    • A quantitative comparison of functional and anti-ischaemic effects of the phosphodiesterase-inhibitors, amrinone, milrinone and levosimendan in rabbit isolated hearts
    • RUMP, A. F. E., ACAR, D. AND KLAUS, W.: A quantitative comparison of functional and anti-ischaemic effects of the phosphodiesterase-inhibitors, amrinone, milrinone and levosimendan in rabbit isolated hearts. Br. J. Pharmacol. 112: 757-762, 1994a.
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 757-762
    • Rump, A.F.E.1    Acar, D.2    Klaus, W.3
  • 28
    • 0028339593 scopus 로고
    • Functional and antiischemic effects of the phosphodiesterase inhibitor levosimendan in isolated rabbit hearts
    • RUMP, A. F. E., ACAR, D., ROSEN, R. AND KLAUS, W.: Functional and antiischemic effects of the phosphodiesterase inhibitor levosimendan in isolated rabbit hearts. Pharmacol. Toxicol. 74: 244-248, 1994b.
    • (1994) Pharmacol. Toxicol. , vol.74 , pp. 244-248
    • Rump, A.F.E.1    Acar, D.2    Rosen, R.3    Klaus, W.4
  • 31
    • 0011728889 scopus 로고
    • Basis of the cardiac resting potential
    • ed. by N. Sperelakis, Chap. 3, Kluwer Academic Publishers, Norwell, MA
    • SPERELAKIS, N.: Basis of the cardiac resting potential. In: Physiology and Pathology of the Heart, 3rd ed., ed. by N. Sperelakis, Chap. 3, pp. 55-76, Kluwer Academic Publishers, Norwell, MA, 1995.
    • (1995) Physiology and Pathology of the Heart, 3rd Ed. , pp. 55-76
    • Sperelakis, N.1
  • 32
    • 0017143158 scopus 로고
    • A metabolic control mechanism for calcium ion influx that may protect the ventricular myocardial cell
    • SPERELAKIS, N. AND SCHNEIDER, J. A.: A metabolic control mechanism for calcium ion influx that may protect the ventricular myocardial cell. Am. J. Cardiol. 37: 1079-1085, 1976.
    • (1976) Am. J. Cardiol. , vol.37 , pp. 1079-1085
    • Sperelakis, N.1    Schneider, J.A.2
  • 33
    • 0027299745 scopus 로고
    • On the crawling of animal cells
    • STOSSEL, T. P.: On the crawling of animal cells. Science 260: 1086-1094, 1993.
    • (1993) Science , vol.260 , pp. 1086-1094
    • Stossel, T.P.1
  • 34
    • 0029038397 scopus 로고
    • Hemodynamic and neurohumoral effects of levosimendan, a new calcium sensitizer, at rest and during exercise in healthy men
    • SUNDBERG, S., LILLEBERG, J., NIEMINEN, M. S. AND LEHTONEN, L.: Hemodynamic and neurohumoral effects of levosimendan, a new calcium sensitizer, at rest and during exercise in healthy men. Am. J. Cardiol. 75: 1061-1066, 1995.
    • (1995) Am. J. Cardiol. , vol.75 , pp. 1061-1066
    • Sundberg, S.1    Lilleberg, J.2    Nieminen, M.S.3    Lehtonen, L.4
  • 36
    • 0028873314 scopus 로고    scopus 로고
    • + channel-opening drugs. Am. J. Physiol. 269 (Cell Physiol. 38: C525-C545, 1995.
    • (1995) Cell Physiol. , vol.38
  • 37
    • 0023266532 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
    • THE CONSENSUS TRIAL STCDY GHOUP: Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N. Engl. J. Med. 316: 1429-1435, 1987.
    • (1987) N. Engl. J. Med. , vol.316 , pp. 1429-1435
  • 38
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • THE SOLVD INVESTIGATORS: Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N. Engl. J. Med. 325: 293-302, 1991.
    • (1991) N. Engl. J. Med. , vol.325 , pp. 293-302
  • 39
    • 0024850353 scopus 로고
    • Apparent competition between ATP and the potassium channel opener RP 49356 on ATP-sensitive K channels of cardiac myocytes
    • THURINGER, D. AND ESCANDE, D.: Apparent competition between ATP and the potassium channel opener RP 49356 on ATP-sensitive K channels of cardiac myocytes. Mol. Pharmacol. 36: 897-902, 1989.
    • (1989) Mol. Pharmacol. , vol.36 , pp. 897-902
    • Thuringer, D.1    Escande, D.2
  • 40
    • 0025848736 scopus 로고
    • + channel in ventricular cell of guinea-pig
    • Lond.
    • + channel in ventricular cell of guinea-pig. J. Physiol. (Lond.) 437: 239-256, 1991.
    • (1991) J. Physiol. , vol.437 , pp. 239-256
    • Tung, R.T.1    Kcrachi, Y.2
  • 42
    • 0342561598 scopus 로고    scopus 로고
    • Cardiac electrophysiological effects of levosimendan, a new calcium sensitizer
    • VIRAG, L., HALA, O., MARTON, A., VARRO, A. AND PAPP, J. G.: Cardiac electrophysiological effects of levosimendan, a new calcium sensitizer. Gen. Pharmacol. 27: 551-556, 1996.
    • (1996) Gen. Pharmacol. , vol.27 , pp. 551-556
    • Virag, L.1    Hala, O.2    Marton, A.3    Varro, A.4    Papp, J.G.5
  • 43
    • 0031066156 scopus 로고    scopus 로고
    • 2+ channel currents by intracellular ATP in smooth muscle cells of rat mesenteric artery
    • 2+ channel currents by intracellular ATP in smooth muscle cells of rat mesenteric artery. Am. J. Physiol. 272 (Heart Circ. Physiol. 41): H814-H819, 1997.
    • Am. J. Physiol. , vol.272
    • Yokoshiki, H.1    Katslbe, Y.2    Sperelakis, N.3
  • 44
    • 15144348259 scopus 로고    scopus 로고
    • 2+ channel currents by intracellular ATP in smooth muscle cells of rat mesenteric artery. Am. J. Physiol. 272 (Heart Circ. Physiol. 41): H814-H819, 1997.
    • (1997) Heart Circ. Physiol. , vol.41
  • 45
    • 0029880144 scopus 로고    scopus 로고
    • Inhibition of L-type calcium current in rat ventricular cells by the tyrosine kinase inhibitor, genistein and its inactive analog, daidzein
    • YOKOSHIKI, H., SUMII, K. AND SPERELAKIS, N.: Inhibition of L-type calcium current in rat ventricular cells by the tyrosine kinase inhibitor, genistein and its inactive analog, daidzein. J. Mol. Cell. Cardiol. 28: 807-814, 1996.
    • (1996) J. Mol. Cell. Cardiol. , vol.28 , pp. 807-814
    • Yokoshiki, H.1    Sumii, K.2    Sperelakis, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.