Inhibition of L-type calcium current in rat ventricular cells by the tyrosine kinase inhibitor, genistein and its inactive analog, daidzein

Journal of Molecular and Cellular Cardiology

Volumn 28, Issue 4, 1996, Pages 807-814

  Yokoshiki, Hisashi ^a   Sumii, Kotaro ^a   Sperelakis, Nicholas ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Ca2+ current; Cardiomyocytes; Daidzein inhibition; Genistein inhibition; Newborn rat heart; Tyrosine kinase activity; Whole cell voltage clamp

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; DAIDZEIN; GENISTEIN; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; ENZYME ACTIVITY; HEART MUSCLE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT;

EID: 0029880144     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0075     Document Type: Article

References (35)

1. AKIYAMA T, ISHIDA J, NAKAGAWA S, OGAWARA H, WATANABE S, ITOH N, SHIBUYA M, FUKAMI Y, 1987. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262: 5592-5595.
2. BARNES S, PETERSON TG, 1995. Biochemical targets of the isoflavone genistein in tumor cell lines. PSEBM 208: 103-108.
3. BISHOP JM, 1983. Cellular oncogenes and retroviruses. Ann Rev Biochem 52: 301-354.
4. CATARSI S, DRAPEAU P, 1993. Tyrosine kinase-dependent selection of transmitter responses induced by neuronal contact. Nature 363: 353-355.
5. COLLETT MS, ERIKSON RL, 1978. Protein kinase activity associated with the avian sarcoma virus src gene product. Proc Natl Acad Sci USA 75: 2021-2024.
6. 9-bradykinin or of α-thrombin in rabbit aortic rings. Br J Pharmacol 105: 959-967.
7. DI SALVO J, STEUSLOFF A, SEMENCHUK L, SATOH S, KOLQUIST K, PFITZER G, 1993. Tyrosine kinase inhibitors suppress agonist-induced contraction in smooth muscle. Biochem Biophys Res Commun 190: 968-974.
8. EK B, WESTERMARK B, WASTESON A, HELDIN CH, 1982. Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor. Nature 295: 419-420.
9. FANTL WJ, JOHNSON DE, WILLIAMS LT, 1993. Signalling by receptor tyrosine kinases. Annu Rev Biochem 62: 453-481.
10. HADDAD GE, SPERELAKIS N, BKAILY G, 1995. Regulation of calcium channel by cyclic GMP-dependent protein kinase in chick heart cells. Mol Cell Biochem 148: 84-94.
11. HANKS SK, QUINN AM, HUNTER T, 1988. The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains. Science 241: 42-52.
12. HOLLENBERG MD, 1994. Tyrosine kinase pathways and the regulation of smooth muscle contractility. Trends Pharmacol Sci 15: 108-114.
13. HUNTER T, SEFTON BM, 1980. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc Natl Acad Sci USA 77: 1311-1315.
14. HUNTER T, COOPER JA, 1985. Protein-tyrosine kinases. Ann Rev Biochem 54: 897-930.
15. INOUE R, WANIISHI Y, YAMADA K, ITO Y, 1994. A possible role of tyrosine kinases in the regulation of muscarinic receptor-activated cation channels. Biochem Biophys Res Commun 203: 1392-1397.
16. KUSAKA M, SPERELAKIS N, 1995. Inhibition of L-type calcium current by genistein, a tyrosine kinase inhibitor, in pregnant rat myometrial cells. BBA 1240: 196-200.
17. KUSUGA M, ZICK Y, BLITHE DL, CRETTAZ M, KAHN CR, 1982. Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system. Nature 298: 667-669.
18. LEE PL, JOHNSON DE, COUSENS LS, FRIED VA, WILLIAMS LT, 1989. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science 245: 57-60.
19. MAHER PA, 1991. Tissue-dependent regulation of protein tyrosine kinase activity during embryonic development. J Cell Biol 112: 955-963.
20. MAISONPIERRE PC, GOLDFARB M, YANCOPOULOS GD, GAO G, 1993. Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family. Oncogene 8: 1631-1637.
21. MARGOLIS B, RHEE SG, FELDER S, MERVIC M, LYALL R, LEVITZKI A, ULLRICH A, ZILBERSTEIN A, SCHLESSINGER J, 1989. EGF induces tyrosine phosphorylation of phospholipase C-II: A potential mechanism for EGF receptor signaling. Cell 57: 1101-1107.
22. MINAMI K, FUKUZAWA K, INOUE I, 1994. Regulation of a non-selective cation channel of cultured porcine coronary artery smooth muscle cells by tyrosine kinase. Pflügers Arch 426: 254-257.
23. 2-mediated human platelet responses. Mol Pharmacol 39:475-480.
24. RUTA M, BURGESS W, GIVOL D, EPSTEIN J, NEIGER N, KAPLOW J, CRUMLEY G, DIONNE C, JAYE M, SCHLESSINGER J, 1989. Receptor for acidic fibroblast growth factor is related to the tyrosine kinase encoded by the fms-like gene (FLG). Proc Natl Acad Sci USA 86: 8722-8726.
25. SADOSHIMA J, IZUMO S, 1993. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism. EMBO J 12: 1681-1692.
26. SCHOLAR EM, TOEWS ML, 1994. Inhibition of invasion of murine mammary carcinoma cells by the tyrosine kinase inhibitor genistein. Cancer Lett 87: 159-162.
27. + currents by tyrosine kinase inhibitors genistein and ST 638. Circ Res 76: 310-316.
28. SPERELAKISN, 1986. Regulation of calcium slow channels in myocardial cells by cyclic nucleotides and phosphorylation. In: RJ Solaro ed. Protein Phosphorylation in Heart Muscle. CRC Press, 55-83.
29. SPERELAKIS N, XIONG Z, HADDAD G, MASUDA H, 1994. Regulation of slow calcium channels of myocardial cells and vascular smooth muscle cells by cyclic nucleotides and phosphorylation. Mol Cell Biochem 140: 103-117.
30. SUMII K, SPERELAKIS N, 1995. Cyclic GMP-dependent protein kinase regulation of the L-type calcium current in rat ventricular myocytes. Circ Res 77: 803-812.
31. TRAUTWEIN W, HESCHELER J, 1990. Regulation of cardiac L-type calcium current by phosphorylation and G proteins. Annu Rev Physiol 52: 257-274.
32. WAHLER GM, RUSCH NJ, SPERELAKIS N, 1990. 8-bromocyclic GMP inhibits the calcium channel current in embryonic chick ventricular myocytes. Can J Physiol Pharm 68: 531-534.
33. WIJETUNGE S, AALKJAER C, SCHACHTER M, HUGHES AD, 1992. Tyrosine kinase inhibitors block calcium channel currents in vascular smooth muscle cells. Biochem Biophys Res Commun 189: 1620-1623.
34. YANG S, SAIFEDDINE M, HOLLENBERG MD, 1992. Tyrosine kinase inhibitors and the contractile action of epidermal growth factor-urogastrone and other agonists in gastric smooth muscle. Can J Physiol Pharmacol 70: 85-93.
35. YANG S, SAIFEDDINE M, LANIYONU A, HOLLENBERG MD, 1993. Distinct signal transduction pathways for angiotensin-II in guinea pig gastric smooth muscle: differential blockade by indomethacin and tyrosine kinase inhibitors. J Pharmacol Exp Ther 264: 958-966.