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Volumn 15, Issue 13, 1996, Pages 3306-3314

A point mutation in the microtubule binding region of the Ncd motor protein reduces motor velocity

Author keywords

Kinesin; Microtubule binding; Microtubule motor; Mutant; Ncd

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; HYBRID PROTEIN; KINESIN; NUCLEOTIDE; RECOMBINANT PROTEIN;

EID: 0030015952     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00695.x     Document Type: Article
Times cited : (24)

References (36)
  • 1
    • 0021808444 scopus 로고
    • A novel brain ATPase with properties expected for the fast axonal transport motor
    • Brady, S.T. (1985) A novel brain ATPase with properties expected for the fast axonal transport motor Nature, 317, 73-75.
    • (1985) Nature , vol.317 , pp. 73-75
    • Brady, S.T.1
  • 2
    • 0027712714 scopus 로고
    • Expression of microtubule motor proteins in bacteria for characterization in in vitro motility assays
    • Chandra, R. and Endow, S.A. (1993) Expression of microtubule motor proteins in bacteria for characterization in in vitro motility assays. Methods Cell Biol., 39, 115-127.
    • (1993) Methods Cell Biol. , vol.39 , pp. 115-127
    • Chandra, R.1    Endow, S.A.2
  • 3
    • 0027463255 scopus 로고
    • Structural and functional domains of the Drosophila ncd microtubule motor protein
    • Chandra, R., Salmon, E.D., Erickson, H.P., Lockhart, A. and Endow, S.A. (1993) Structural and functional domains of the Drosophila ncd microtubule motor protein. J. Biol. Chem., 268, 9005-9013.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9005-9013
    • Chandra, R.1    Salmon, E.D.2    Erickson, H.P.3    Lockhart, A.4    Endow, S.A.5
  • 5
    • 0025275327 scopus 로고
    • Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin
    • Endow, S.A., Henikoff, S. and Soler-Niedziela, L. (1990) Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin. Nature, 345, 81-83.
    • (1990) Nature , vol.345 , pp. 81-83
    • Endow, S.A.1    Henikoff, S.2    Soler-Niedziela, L.3
  • 6
    • 0028231705 scopus 로고
    • Mutants of the Drosophila ncd microtubule motor protein cause centrosomal and spindle pole defects in mitosis
    • Endow, S.A., Chandra, R., Komma, D.J., Yamamoto, A.H. and Salmon, E.D. (1994a) Mutants of the Drosophila ncd microtubule motor protein cause centrosomal and spindle pole defects in mitosis. J. Cell Sci., 107, 859-867.
    • (1994) J. Cell Sci. , vol.107 , pp. 859-867
    • Endow, S.A.1    Chandra, R.2    Komma, D.J.3    Yamamoto, A.H.4    Salmon, E.D.5
  • 7
    • 0028245510 scopus 로고
    • Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends
    • Endow, S.A., Kang, S.J., Satterwhite, L.L., Rose, M.D., Skeen, V.P. and Salmon, E.D. (1994b) Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends. EMBO J., 13, 2708-2713.
    • (1994) EMBO J. , vol.13 , pp. 2708-2713
    • Endow, S.A.1    Kang, S.J.2    Satterwhite, L.L.3    Rose, M.D.4    Skeen, V.P.5    Salmon, E.D.6
  • 8
    • 0028985886 scopus 로고
    • Pathway of processive ATP hydrolysis by kinesin
    • Gilbert, S.P., Webb, M.R., Brune, M. and Johnson, K.A. (1995) Pathway of processive ATP hydrolysis by kinesin. Nature, 373, 671-676.
    • (1995) Nature , vol.373 , pp. 671-676
    • Gilbert, S.P.1    Webb, M.R.2    Brune, M.3    Johnson, K.A.4
  • 9
    • 0024448151 scopus 로고
    • Calculation of protein extinction coefficients from amino acid sequence data
    • Gill, S.C. and von Hippel, P.H. (1989) Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem., 182, 319-329.
    • (1989) Anal. Biochem. , vol.182 , pp. 319-329
    • Gill, S.C.1    Von Hippel, P.H.2
  • 10
    • 0027466796 scopus 로고
    • Microtubule-associated motility in cytoplasmic extracts of sea urchin eggs
    • Gliksman, N.R. and Salmon, E.D. (1993) Microtubule-associated motility in cytoplasmic extracts of sea urchin eggs. Cell Motil. Cytoskel., 24, 167-178.
    • (1993) Cell Motil. Cytoskel. , vol.24 , pp. 167-178
    • Gliksman, N.R.1    Salmon, E.D.2
  • 11
    • 1542353988 scopus 로고
    • Kinesin ATPase: Rate-limiting ADP release
    • Hackney, D.D. (1988) Kinesin ATPase: rate-limiting ADP release. Proc. Nayl Acad. Sci. USA, 85, 6314-6318.
    • (1988) Proc. Nayl Acad. Sci. USA , vol.85 , pp. 6314-6318
    • Hackney, D.D.1
  • 12
    • 0027053473 scopus 로고
    • The Drosophila claret microtubule motor protein is spindle-associated in meiotic and mitolic cells
    • Hatsumi, M. and Endow, S.A. (1992a) The Drosophila claret microtubule motor protein is spindle-associated in meiotic and mitolic cells. J. Cell Sci., 103, 1013-1020.
    • (1992) J. Cell Sci. , vol.103 , pp. 1013-1020
    • Hatsumi, M.1    Endow, S.A.2
  • 13
    • 0026519303 scopus 로고
    • Mutants of the microtubule motor protein, nonclaret disjunctional, affect spindle structure and chromosome movement in meiosis and mitosis
    • Hatsumi, M. and Endow, S.A. (1992b) Mutants of the microtubule motor protein, nonclaret disjunctional, affect spindle structure and chromosome movement in meiosis and mitosis. J. Cell Sci., 101, 547-559.
    • (1992) J. Cell Sci. , vol.101 , pp. 547-559
    • Hatsumi, M.1    Endow, S.A.2
  • 14
    • 0028363764 scopus 로고
    • Drosophila kinesin minimal motor domain expressed in Escherichia coli: Purification and kinetic characterization
    • Huang, T.-G. and Hackney, D.D. (1994) Drosophila kinesin minimal motor domain expressed in Escherichia coli: purification and kinetic characterization. J. Biol. Chem., 269, 16493-16501.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16493-16501
    • Huang, T.-G.1    Hackney, D.D.2
  • 15
    • 0020322590 scopus 로고
    • Developmental regulation of Drosophila α-tubulin genes
    • Kalfayan, L. and Wensinck, P.C. (1982) Developmental regulation of Drosophila α-tubulin genes. Cell, 29, 91-98.
    • (1982) Cell , vol.29 , pp. 91-98
    • Kalfayan, L.1    Wensinck, P.C.2
  • 16
    • 0026078022 scopus 로고
    • Separation of meiotic and mitotic effects of claret nondisjunctional on chromosome segregation in Drosophila
    • Komma, D.J., Horne, A.S. and Endow, S.A. (1991) Separation of meiotic and mitotic effects of claret nondisjunctional on chromosome segregation in Drosophila. EMBO J., 10, 419-424.
    • (1991) EMBO J. , vol.10 , pp. 419-424
    • Komma, D.J.1    Horne, A.S.2    Endow, S.A.3
  • 17
    • 0040150300 scopus 로고
    • Claret and non-disjunction in Drosophila melanogaster
    • Lewis, E.B. and Gencarella, W. (1952) Claret and non-disjunction in Drosophila melanogaster. Genetics, 37, 600-601.
    • (1952) Genetics , vol.37 , pp. 600-601
    • Lewis, E.B.1    Gencarella, W.2
  • 18
    • 0028040295 scopus 로고
    • Origins of reversed directionality in the ncd molecular motor
    • Lockhart, A. and Cross, R.A. (1994) Origins of reversed directionality in the ncd molecular motor. EMBO J., 13, 751-757.
    • (1994) EMBO J. , vol.13 , pp. 751-757
    • Lockhart, A.1    Cross, R.A.2
  • 19
    • 0029012977 scopus 로고
    • Kinesin and ncd bind through a single head to microtubules and compete for a shared MT binding site
    • Lockhart, A., Crevel, I.M.-T. and Cross, R.A. (1995a) Kinesin and ncd bind through a single head to microtubules and compete for a shared MT binding site. J. Mol. Biol., 249, 763-771.
    • (1995) J. Mol. Biol. , vol.249 , pp. 763-771
    • Lockhart, A.1    Crevel, I.M.-T.2    Cross, R.A.3
  • 20
    • 0029148759 scopus 로고
    • ADP release is the rate-limiting step of the MT activated ATPase of non-claret disjunctional and kinesin
    • Lockhart, A., Cross, R.A. and McKillop, D.F.A. (19956) ADP release is the rate-limiting step of the MT activated ATPase of non-claret disjunctional and kinesin. FEBS Lett., 368, 531-535.
    • (1995) FEBS Lett. , vol.368 , pp. 531-535
    • Lockhart, A.1    Cross, R.A.2    McKillop, D.F.A.3
  • 21
    • 0028865659 scopus 로고
    • Mechanism of microtubule kinesin ATPase
    • Ma, Y.Z. and Taylor, E.W. (1995) Mechanism of microtubule kinesin ATPase. Biochemistry, 34, 13242-13251.
    • (1995) Biochemistry , vol.34 , pp. 13242-13251
    • Ma, Y.Z.1    Taylor, E.W.2
  • 22
    • 0027400495 scopus 로고
    • A functionally specialized a-tubulin is required for oocyte meiosis and cleavage mitosis in Drosophila
    • Matthews, K.A., Rees, D. and Kaufman, T.C. (1993) A functionally specialized a-tubulin is required for oocyte meiosis and cleavage mitosis in Drosophila. Development, 117, 977-991.
    • (1993) Development , vol.117 , pp. 977-991
    • Matthews, K.A.1    Rees, D.2    Kaufman, T.C.3
  • 23
    • 0025608711 scopus 로고
    • The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor
    • McDonald, H.B., Stewart, R.J. and Goldstein, L.S.B. (1990) The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor. Cell, 63, 1159-1165.
    • (1990) Cell , vol.63 , pp. 1159-1165
    • McDonald, H.B.1    Stewart, R.J.2    Goldstein, L.S.B.3
  • 24
    • 0030111466 scopus 로고    scopus 로고
    • Kinesin proteins: A phylum of motors for microtubule-based motility
    • Moore, J.D. and Endow, S.A. (1996) Kinesin proteins: a phylum of motors for microtubule-based motility. BioEssays, 18, 207-219.
    • (1996) BioEssays , vol.18 , pp. 207-219
    • Moore, J.D.1    Endow, S.A.2
  • 25
    • 0027446475 scopus 로고
    • Chemomechanical cycle of kinesin differs from that of myosin
    • Romberg, L. and Vale, R.D. (1993) Chemomechanical cycle of kinesin differs from that of myosin. Nature, 361, 168-170.
    • (1993) Nature , vol.361 , pp. 168-170
    • Romberg, L.1    Vale, R.D.2
  • 27
    • 0028838570 scopus 로고
    • Expression, purification and ATPase and microtubule binding properties of the ncd motor domain
    • Shimizu, T., Sablin, E., Vale, R.D., Fletterick, R., Pechatnikova, E. and Taylor, E.W. (1995) Expression, purification and ATPase and microtubule binding properties of the ncd motor domain. Biochemistry, 34, 13259-13266.
    • (1995) Biochemistry , vol.34 , pp. 13259-13266
    • Shimizu, T.1    Sablin, E.2    Vale, R.D.3    Fletterick, R.4    Pechatnikova, E.5    Taylor, E.W.6
  • 28
    • 0028826175 scopus 로고
    • The Neurospora organelle motor: A distant relative of conventional kinesin with unconventional properties
    • Steinberg, G. and Schliwa, M (1995) The Neurospora organelle motor: a distant relative of conventional kinesin with unconventional properties. Mol. Biol. Cell, 6, 1605-1618.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 1605-1618
    • Steinberg, G.1    Schliwa, M.2
  • 29
    • 0000366609 scopus 로고
    • The claret mutant type of Drosophila simulans: A study of chromosome elimination and of cell-lineage
    • Sturtevant, A.H. (1929) The claret mutant type of Drosophila simulans: a study of chromosome elimination and of cell-lineage. Z. Wiss. Zool., 135, 323-356.
    • (1929) Z. Wiss. Zool. , vol.135 , pp. 323-356
    • Sturtevant, A.H.1
  • 30
    • 0022294771 scopus 로고
    • Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro
    • Vale, R.D., Schnapp, B.J., Mitchison. T., Steuer, E., Reese, T.S. and Sheetz, M.P. (1985a) Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell, 43, 623-632.
    • (1985) Cell , vol.43 , pp. 623-632
    • Vale, R.D.1    Schnapp, B.J.2    Mitchison, T.3    Steuer, E.4    Reese, T.S.5    Sheetz, M.P.6
  • 31
    • 0022385727 scopus 로고
    • Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility
    • Vale, R.D., Reese, T.S. and Sheetz, M.P. (1985b) Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell 42, 39-50.
    • (1985) Cell , vol.42 , pp. 39-50
    • Vale, R.D.1    Reese, T.S.2    Sheetz, M.P.3
  • 32
    • 0029053823 scopus 로고
    • Chromosomes take the lead in spindle assembly
    • Vernos, I. and Karsenti, E. (1995) Chromosomes take the lead in spindle assembly. Trends Cell Biol., 5, 297-301.
    • (1995) Trends Cell Biol. , vol.5 , pp. 297-301
    • Vernos, I.1    Karsenti, E.2
  • 33
    • 0024094432 scopus 로고
    • Dynamic instability of individual microtubules analysed by video light microscopy: Rate constants and transition frequencies
    • Walker, R.A., O'Brien, E.T., Pryer, N.K., Soboeiro, M.F., Voter, W.A., Erickson, H.P. and Salmon, E.D. (1988) Dynamic instability of individual microtubules analysed by video light microscopy: rate constants and transition frequencies. J. Cell Biol., 107, 1437-1448.
    • (1988) J. Cell Biol. , vol.107 , pp. 1437-1448
    • Walker, R.A.1    O'Brien, E.T.2    Pryer, N.K.3    Soboeiro, M.F.4    Voter, W.A.5    Erickson, H.P.6    Salmon, E.D.7
  • 34
    • 0025186134 scopus 로고
    • The Drosophila claret segregation protein is a minus-end directed motor molecule
    • Walker, R.A., Salmon, E.D. and Endow, S.A. (1990) The Drosophila claret segregation protein is a minus-end directed motor molecule. Nature, 347, 780-782.
    • (1990) Nature , vol.347 , pp. 780-782
    • Walker, R.A.1    Salmon, E.D.2    Endow, S.A.3
  • 35
    • 0020009818 scopus 로고
    • Preparation of tubulin from brain
    • Williams, R.C., Jr and Lee, J.C. (1982) Preparation of tubulin from brain. Methods Enzymol., 85, 376-385.
    • (1982) Methods Enzymol. , vol.85 , pp. 376-385
    • Williams Jr., R.C.1    Lee, J.C.2
  • 36
    • 0024550571 scopus 로고
    • A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses
    • Yang, J.T., Laymon, R.A. and Goldstein, L.S.B. (1989) A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. Cell, 56, 879-889.
    • (1989) Cell , vol.56 , pp. 879-889
    • Yang, J.T.1    Laymon, R.A.2    Goldstein, L.S.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.