Glucose production and gluconeogenesis are negatively related to body weight in mechanically ventilated, very low birth weight neonates

Pediatric Research

Volumn 41, Issue 1, 1997, Pages 132-138

  Keshen, Tamir ^a   Miller, Ronna ^a   Jahoor, Farook ^a   Jaksic, Tom ^a   Reeds, Peter J ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

ARTICLE; ARTIFICIAL VENTILATION; BODY WEIGHT; CLINICAL ARTICLE; GLUCOGENESIS; GLUCONEOGENESIS; HUMAN; NEWBORN; PRIORITY JOURNAL; STATISTICAL ANALYSIS; VERY LOW BIRTH WEIGHT;

EID: 0031032537     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199701000-00021     Document Type: Article

References (25)

1. Bier DM, Leake D, Haymond MW, Arnold KJ, Gruenke LD, Soerling MA, Kipnis DM 1977 Measurement of the "true" glucose production rates in infancy and childhood with 6,6-di-deuteroglucose. Diabetes 26:1016-1023
2. 2]glucose tracers. J Clin Endocrinol Metab 50:456-460
3. Bougneres PF, Karl IE, Hillman LS, Bier DM 1982 Lipid transport in the human newborn: palmitate and glycerol turnover and the contribution of glycerol to hepatic glucose output. J Clin Invest 70:262-270
4. 2]alanine in the human neonate. Am J Physiol 240:E615-E621
5. Cowett RM, Oh W, Schwartz R 1983 Persistent glucose production during glucose infusion in the neonate. J Clin Invest 71:467-471
6. Cowett RM, Anderson GE, Maguire CA, Oh W 1988 Ontogeny of glucose homeostasis in low-birth-weight infants. J Pediatr 112:462-465
7. Hertz DE, Karn CA, Liu YM, Liechty EA, Denne SC 1993 Intravenous glucose suppresses glucose production but not proteolysis in extremely premature infants. J Clin Invest 92:1752-1758
8. Yunis KA, Oh W, Kalhan S, Cowett RM 1992 Glucose kinetics following administration of an intravenous fat emulsion to low birth-weight neonates. Am J Physiol 263:E844-E849
9. Fjeld CR, Cole SF, Bier DM 1992 Energy expenditure, lipolysis and glucose production in preterm infants treated with theophylline. Pediatr Res 32:693-698
10. Previs SF, Fernandez CA, Yang D, Soloviev MV, David F, Brunengraber H 1995 Limitations of the mass isotopomer distribution analysis of glucose to study gluconeogenesis. Substrate cycling between glycerol and triose phosphates in liver. J Biol Chem 270:19806-19015
11. Landau BR, Fernandez CA, Previs SF, Ekberg K, Chandramouli V, Wahren J, Kalhan SC, Brunengraber H 1995 A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in humans. Am J Physiol 269: E18-E26
12. Neese RA, Schwartz JM, Faix D, Turner S, Letscher A, Vu D, Hellerstein MK 1995 Gluconeogenesis and intrahepatic triose phosphate flux in response to fasting or substrate loads. J Biol Chem 270:14452-14466
13. 13C]glucose. Am J Physiol 245: E476-E482
14. Kalderon B, Gopher A, Lapidot A 1986 Metabolic pathways leading to liver glycogen repletion in vivo, studied by GC-MS and NMR. FEBS Lett 204:29-32
15. 13C]glucose in rats. J Biol Chem 264:12994-13004
16. 13C-NMR study. Proc Natl Acad Sci USA 86:4690-4694
17. Miller R, Jahoor F, Reeds PJ, Heird WC, Jaksic T 1995 A new stable isotope technique to assess human neonatal amino acid synthesis. J Pediatr Surg 30:1321-1329
18. Jahoor F, Burrin DG, Reeds PJ, Frazer M 1994 Measurement of plasma protein synthesis rate in the infant pig: an investigation of alternative tracer approaches. Am J Physiol 267:R221-R227
19. Reeds PJ, Hachey DL, Patterson BW, Motil KJ, Klein PD 1992 VLDL apolipoprotein B-100, a potential indicator of the isotopic labeling of the hepatic protein synthetic precursor pool in humans: studies with multiple stable isotopically labeled amino acids. J Nutr 122:457-467
20. Berthold HK, Reeds PJ, Klein PD. 1995 Isotopic evidence for the differential regulation of arginine and proline synthesis in man. Metabolism 44:466-473
21. 13C. J Clin Endocrinol Metab 43:704-707
22. Cowett RM, Wolfe RR 1991 Glucose and lactate kinetics in the neonate. J Dev Physiol 16:341-347
23. Bougneres P-F, Rocchiccioli F, Nurjhan N, Zeller J 1995 Stable isotope determination of plasma lactate conversion into glucose in fasting infants. Am J Physiol 268:E652-E659
24. Des Rosiers C, Di Donato L, Comte B, Laplante A, Marcoux C, David F, Fernandez CA, Brunengraber H 1995 Isotopomer analysis of citric acid cycle and gluconeogenesis in rat liver. Reversibility of isocitrate dehydrogenase and involvement of ATP-citrate lyase in gluconeogenesis. J Biol Chem 270:10027-10036
25. 13C-mass isotopomer distribution analysis of intermediates. J Biol Chem 270:10037-10042