Novel and potent BK channel openers: CGS 7181 and its analogs

Drug Development Research

Volumn 41, Issue 1, 1997, Pages 10-21

  Hu, Shiling ^a   Fink, Cynthia A ^a   Kim, Helen S ^a   Lappe, Rodney W ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Ca2+ activated K+ channel; CGS 7181; CGS 7184; CGS 7590; CGS 7725; Inside out single channel recording; Patch clamp technique; Whole cell recording

Indexed keywords

1 (5 CHLORO 2 HYDROXYPHENYL) 5 TRIFLUOROMETHYL 2 BENZIMIDAZOLONE; 2 HYDROXY 1 [[(4 METHYLPHENYL)AMINO]OXO] 6 TRIFLUOROMETHYL 1H INDOLE 3 CARBOXYLIC ACID ETHYL ESTER; CGS 7181; NIFEDIPINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; TETRYLAMMONIUM; UNCLASSIFIED DRUG;

ARTICLE; BLADDER; CHANNEL GATING; CORONARY ARTERY; DOG; DOSE RESPONSE; IN VITRO STUDY; PATCH CLAMP; SMOOTH MUSCLE FIBER; SWINE;

EID: 0030704668     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199705)41:1<10::AID-DDR2>3.0.CO;2-V     Document Type: Article

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