메뉴 건너뛰기




Volumn 34, Issue 3, 1997, Pages 230-234

A liquid mixed meal or exogenous glucagon-like peptide 1 (GLP-1) do not alter plasma leptin concentrations in healthy volunteers

Author keywords

C peptide; Glucagon like peptide 1; Leptin; Obesity

Indexed keywords

AMINO ACID; CREATININE; GENE PRODUCT; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HEMOGLOBIN A1C; INSULIN; LEPTIN; SUCROSE;

EID: 0030666310     PISSN: 09405429     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005920050079     Document Type: Article
Times cited : (15)

References (47)
  • 4
    • 0029939065 scopus 로고    scopus 로고
    • Decreased food intake does not completely account for adiposity reduction after ob protein infusion
    • Levin N, Nelson C, Gurney A, Vandlen R, DeSauvage F, Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc Natl Acad Sci USA 93:1726-1730, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1726-1730
    • Levin, N.1    Nelson, C.2    Gurney, A.3    Vandlen, R.4    DeSauvage, F.5
  • 7
    • 85050956429 scopus 로고
    • Induction and reversibility of an obesity syndrome by intracerebroventricular neuropeptide Y administration to normal rats
    • Vettor R, Zarjevski N, Cusin I, Rohner-Jeanrenaud F, Jeanrenaud B, Induction and reversibility of an obesity syndrome by intracerebroventricular neuropeptide Y administration to normal rats. Diabetologia 37:1202-1208, 1994
    • (1994) Diabetologia , vol.37 , pp. 1202-1208
    • Vettor, R.1    Zarjevski, N.2    Cusin, I.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5
  • 8
    • 0028228615 scopus 로고
    • Neuropeptide Y and energy balance one way ahead for the treatment of obesity?
    • Dryden S, Frankish H, Qiong W, Williams G, Neuropeptide Y and energy balance one way ahead for the treatment of obesity? Eur J Clin Invest 24:293-308, 1994
    • (1994) Eur J Clin Invest , vol.24 , pp. 293-308
    • Dryden, S.1    Frankish, H.2    Qiong, W.3    Williams, G.4
  • 9
    • 0030021782 scopus 로고
    • Intracerebroventricular administration of neuropeptide Y to normal rats increases obese gene expression in white adipose tissue
    • Sainsbury A, Cusin I, Doyle P, Rohner- Jeanreaud F, Jeanreaud B, Intracerebroventricular administration of neuropeptide Y to normal rats increases obese gene expression in white adipose tissue. Diabetologia 39:353-356, 1995
    • (1995) Diabetologia , vol.39 , pp. 353-356
    • Sainsbury, A.1    Cusin, I.2    Doyle, P.3    Rohner-Jeanreaud, F.4    Jeanreaud, B.5
  • 11
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin-[9-39]-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting β-ceils
    • Göke R, Fehmann HC, Linn T, Schmidt H, Krause M, Eng J, Göke B, Exendin-4 is a high potency agonist and truncated exendin-[9-39]-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting β-ceils. J Biol Chem 268:19650-19655, 1993
    • (1993) J Biol Chem , vol.268 , pp. 19650-19655
    • Göke, R.1    Fehmann, H.C.2    Linn, T.3    Schmidt, H.4    Krause, M.5    Eng, J.6    Göke, B.7
  • 12
    • 0027425034 scopus 로고
    • Cloning and functional characterization of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) is an antagonist of the receptor
    • Thorens B, Poerret A, Buhler L, Deng SP, Morel P, Widman C, Cloning and functional characterization of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) is an antagonist of the receptor. Diabetes 42:1678-1682, 1993
    • (1993) Diabetes , vol.42 , pp. 1678-1682
    • Thorens, B.1    Poerret, A.2    Buhler, L.3    Deng, S.P.4    Morel, P.5    Widman, C.6
  • 14
    • 9844244941 scopus 로고    scopus 로고
    • Distribution of glucagon-like peptide 1 and other preproglucagon derived peptides in the rat hypothalamus and brain stem
    • Ørskov C, Tang-Christiansen M, Holst JJ, Larsen PJ, Distribution of glucagon-like peptide 1 and other preproglucagon derived peptides in the rat hypothalamus and brain stem. Diabetes 45 [Suppl 2]:546, 1996
    • (1996) Diabetes , vol.45 , Issue.2 SUPPL. , pp. 546
    • Ørskov, C.1    Tang-Christiansen, M.2    Holst, J.J.3    Larsen, P.J.4
  • 17
    • 0023266561 scopus 로고
    • Identification and localization of glucagon-like peptide-1 and its receptor in rat brain
    • Shimizu I, Hirota M, Ohboshi C, Shima K, Identification and localization of glucagon-like peptide-1 and its receptor in rat brain. Endocrinology 121:1076-1082, 1987
    • (1987) Endocrinology , vol.121 , pp. 1076-1082
    • Shimizu, I.1    Hirota, M.2    Ohboshi, C.3    Shima, K.4
  • 18
    • 0029903111 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide 1
    • Ørskov C, Poulsen SS, Møller M, Holst JJ, Glucagon-like peptide 1 receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide 1. Diabetes 45:832-835, 1996
    • (1996) Diabetes , vol.45 , pp. 832-835
    • Ørskov, C.1    Poulsen, S.S.2    Møller, M.3    Holst, J.J.4
  • 19
    • 0028177577 scopus 로고
    • Glucagon-like-peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man
    • Wettergren A, Petersen H, Ørskov C, Christiansen J, Sheikh SP, Holst JJ, Glucagon-like-peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man. Scand J Gastroenterol 29:501-505, 1994
    • (1994) Scand J Gastroenterol , vol.29 , pp. 501-505
    • Wettergren, A.1    Petersen, H.2    Ørskov, C.3    Christiansen, J.4    Sheikh, S.P.5    Holst, J.J.6
  • 20
    • 0029074964 scopus 로고
    • Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers. Dose-response relationships
    • Ritzel R, Ørskov C, Holst JJ, Nauck MA, Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers. Dose-response relationships. Diabetologia 38:720-725, 1995
    • (1995) Diabetologia , vol.38 , pp. 720-725
    • Ritzel, R.1    Ørskov, C.2    Holst, J.J.3    Nauck, M.A.4
  • 22
    • 0027141309 scopus 로고
    • Presence of glucagon and glucagon-like peptide-I-(7-36)-amide receptors in solubilized membranes from human adipose tissue
    • Mérida E, Delgado E, Molina LM, Villanueva-Peñcarillo MLM, Valverde I, Presence of glucagon and glucagon-like peptide-I-(7-36)-amide receptors in solubilized membranes from human adipose tissue. J Clin Endocrinol Metab 77:1654-1657, 1993
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1654-1657
    • Mérida, E.1    Delgado, E.2    Molina, L.M.3    Villanueva-Peñcarillo, M.L.M.4    Valverde, I.5
  • 23
    • 0028077525 scopus 로고
    • Glucagon-like peptide-I-(7-36)-amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: One of several potential extrapancreatic sites of GLP-1 action
    • Egan JM, Montrose-Rafizadeh C, Wang Y, Bernier M, Roth J, Glucagon-like peptide-I-(7-36)-amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: one of several potential extrapancreatic sites of GLP-1 action. Endocrinology 135:2070-2075, 1994
    • (1994) Endocrinology , vol.135 , pp. 2070-2075
    • Egan, J.M.1    Montrose-Rafizadeh, C.2    Wang, Y.3    Bernier, M.4    Roth, J.5
  • 24
    • 0025808278 scopus 로고
    • Effect of the enteropancreatic hormones gastric inhibitory polypeptide and glucagon-like peptide-1(7-36)amide, on fatty acid synthesis in explants of rat adipose tissue
    • Oben J, Morgan J, Fletcher J, Marks V, Effect of the enteropancreatic hormones gastric inhibitory polypeptide and glucagon-like peptide-1(7-36)amide, on fatty acid synthesis in explants of rat adipose tissue. J Endocrinol 130:267-272, 1991
    • (1991) J Endocrinol , vol.130 , pp. 267-272
    • Oben, J.1    Morgan, J.2    Fletcher, J.3    Marks, V.4
  • 26
    • 0029983180 scopus 로고    scopus 로고
    • Obese gene expression: Reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity
    • Mizuno TM, Bergen H, Funabashi T, Kleopoulos SP, Zhong YG, Bauman WA, Mobbs CV, Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity. Proc Natl Acad Sci USA 93:3434-3438, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3434-3438
    • Mizuno, T.M.1    Bergen, H.2    Funabashi, T.3    Kleopoulos, S.P.4    Zhong, Y.G.5    Bauman, W.A.6    Mobbs, C.V.7
  • 27
    • 0029924714 scopus 로고    scopus 로고
    • Insulin increases plasma leptin concentrations in normal subjects and patients with NIDDM
    • Malmström R, Taskinen M-R, Karonen S-L, Yki-Järvinen H, Insulin increases plasma leptin concentrations in normal subjects and patients with NIDDM. Diabetologia 39:993-996, 1996
    • (1996) Diabetologia , vol.39 , pp. 993-996
    • Malmström, R.1    Taskinen, M.-R.2    Karonen, S.-L.3    Yki-Järvinen, H.4
  • 28
    • 0030055611 scopus 로고    scopus 로고
    • The expression of ob gene is not acutely regulated by insulin and fasting in human abdominal subcutaneous adipose tissue
    • Vidal H, Auboeuf D, De Vos P, Staels B, Riou JP, Auwerx J, Laville M, The expression of ob gene is not acutely regulated by insulin and fasting in human abdominal subcutaneous adipose tissue. J Clin Invest 98:251-255, 1996
    • (1996) J Clin Invest , vol.98 , pp. 251-255
    • Vidal, H.1    Auboeuf, D.2    De Vos, P.3    Staels, B.4    Riou, J.P.5    Auwerx, J.6    Laville, M.7
  • 30
    • 0030068620 scopus 로고    scopus 로고
    • Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: Effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in Type 2 (noninsulin-dependent) diabetic patients
    • Willms B, Werner J, Ørskov C, Holst JJ, Creutzfeldt W, Nauck M, Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in Type 2 (noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab 81:327-332, 1996
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 327-332
    • Willms, B.1    Werner, J.2    Ørskov, C.3    Holst, J.J.4    Creutzfeldt, W.5    Nauck, M.6
  • 31
    • 0029796739 scopus 로고    scopus 로고
    • Comparison of hyperinsulinaemic clamp experiments using venous, 'arterialized' venous or capillary euglycaemia
    • Nauck MA, Blietz RW, Qualmann C, Comparison of hyperinsulinaemic clamp experiments using venous, 'arterialized' venous or capillary euglycaemia. Clin Physiol 16: 589-602, 1996
    • (1996) Clin Physiol , vol.16 , pp. 589-602
    • Nauck, M.A.1    Blietz, R.W.2    Qualmann, C.3
  • 32
    • 0023638829 scopus 로고
    • Glucagon-like peptide 1 7-36: A physiological incretin in man
    • Kreymann B, Ghatei MA, Williams G, Bloom SR, Glucagon-like peptide 1 7-36: a physiological incretin in man. Lancet II: 1300-1304, 1987
    • (1987) Lancet , vol.2 , pp. 1300-1304
    • Kreymann, B.1    Ghatei, M.A.2    Williams, G.3    Bloom, S.R.4
  • 33
    • 0027419106 scopus 로고
    • Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide 1 [7-36 amide] infused at near physiological insulinotropic hormone and glucose concentrations
    • Nauck M, Bartels E, Ørskov C, Ebert R, Creutzfeld W, Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide 1 [7-36 amide] infused at near physiological insulinotropic hormone and glucose concentrations. J Clin Endocrinol Metab 76:912-917, 1993
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 912-917
    • Nauck, M.1    Bartels, E.2    Ørskov, C.3    Ebert, R.4    Creutzfeld, W.5
  • 34
    • 0027391607 scopus 로고
    • Preserved incretin activity of glucagon-like peptide 1 (GLP-1) [7-36 amide] but not of synthetic human gastric inhibitory polypeptide (GIP) in patients with Type 2 diabetes mellitus
    • Nauck MA, Heimesaat MM, Ørskov C, Holst JJ, Ebert R, Creutzfeldt W, Preserved incretin activity of glucagon-like peptide 1 (GLP-1) [7-36 amide] but not of synthetic human gastric inhibitory polypeptide (GIP) in patients with Type 2 diabetes mellitus. J Clin Invest 91:301-307, 1993
    • (1993) J Clin Invest , vol.91 , pp. 301-307
    • Nauck, M.A.1    Heimesaat, M.M.2    Ørskov, C.3    Holst, J.J.4    Ebert, R.5    Creutzfeldt, W.6
  • 35
    • 0023104848 scopus 로고
    • Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2)
    • Ørskov C, Holst JJ, Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2). Scand J Clin Lab Invest 47:165-174, 1987
    • (1987) Scand J Clin Lab Invest , vol.47 , pp. 165-174
    • Ørskov, C.1    Holst, J.J.2
  • 36
    • 0028281773 scopus 로고
    • Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide 1 in humans
    • Ørskov C, Rabenhøj L, Wettergren A, Kofod H, Holst JJ, Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide 1 in humans. Diabetes 43:535-539, 1994
    • (1994) Diabetes , vol.43 , pp. 535-539
    • Ørskov, C.1    Rabenhøj, L.2    Wettergren, A.3    Kofod, H.4    Holst, J.J.5
  • 38
    • 0030667056 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy volunteers
    • in press
    • Nauck MA, Niedereichholz U, Ettler R, Holst JJ, Ørskov C, Schmiegel WH, Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy volunteers. Am J Physiol (in press), 1997
    • (1997) Am J Physiol
    • Nauck, M.A.1    Niedereichholz, U.2    Ettler, R.3    Holst, J.J.4    Ørskov, C.5    Schmiegel, W.H.6
  • 40
    • 0027227370 scopus 로고
    • Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: Acute post-prandial and 24-h secretion patterns
    • Elliott RM, Morgan LM, Tredger JA, Deacon S, Wright J, Marks V, Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns. J Endocrinol 138:159-166, 1993
    • (1993) J Endocrinol , vol.138 , pp. 159-166
    • Elliott, R.M.1    Morgan, L.M.2    Tredger, J.A.3    Deacon, S.4    Wright, J.5    Marks, V.6
  • 41
    • 0026051554 scopus 로고
    • Cephalic phase insulin release in normal weight males: Verification and reliability
    • Teff K, Mattes RD, Engelman K, Cephalic phase insulin release in normal weight males: verification and reliability. Am J Physiol 261:E430-435, 1991
    • (1991) Am J Physiol , vol.261
    • Teff, K.1    Mattes, R.D.2    Engelman, K.3
  • 43
    • 9844247895 scopus 로고    scopus 로고
    • Adipose tissue leptin production and plasma leptin kinetics in humans
    • Mohamed-Ali V, Klein S, Landt M, Coppack SW, Adipose tissue leptin production and plasma leptin kinetics in humans. Diabetologia 39 [Suppl 1]:A542, 1996
    • (1996) Diabetologia , vol.39 , Issue.1 SUPPL.
    • Mohamed-Ali, V.1    Klein, S.2    Landt, M.3    Coppack, S.W.4
  • 45
    • 0030010364 scopus 로고    scopus 로고
    • The effect of glucagon-like peptide 1 (GLP-1) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones
    • Toft-Nielsen M, Madsbad S, Holst JJ, The effect of glucagon-like peptide 1 (GLP-1) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones. Diabetes 45:552-556, 1996
    • (1996) Diabetes , vol.45 , pp. 552-556
    • Toft-Nielsen, M.1    Madsbad, S.2    Holst, J.J.3
  • 47
    • 0029819643 scopus 로고    scopus 로고
    • Relationship of plasma leptin to plasma insulin in adiposity in normal weight and overweight women: Effects of dietary fat content and sustained weight loss
    • Havel PJ, Kasim-Karakas S, Mueller W, Johnson PR, Gingerich RL, Stern JS, Relationship of plasma leptin to plasma insulin in adiposity in normal weight and overweight women: effects of dietary fat content and sustained weight loss. J Clin Endocrinol Metab 81:4406-4413, 1996
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4406-4413
    • Havel, P.J.1    Kasim-Karakas, S.2    Mueller, W.3    Johnson, P.R.4    Gingerich, R.L.5    Stern, J.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.