Genetic vaccination against tuberculosis

Springer Seminars in Immunopathology

Volumn 19, Issue 2, 1997, Pages 161-173

  Lowrie, Douglas B ^a   Silva, Celio L ^b   Tascon, Ricardo E ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; MYCOBACTERIUM ANTIGEN;

ADOPTIVE TRANSFER; CYTOTOXIC T LYMPHOCYTE; HUMAN; LYMPHOCYTE CLONE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE; TUBERCULOSIS; TUBERCULOSIS CONTROL; VACCINATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL VACCINES; BCG VACCINE; CHILD; CYTOTOXICITY, IMMUNOLOGIC; HUMANS; INTERFERON TYPE II; LYMPHOKINES; MACACA FASCICULARIS; MACROPHAGES; MICE; MYCOBACTERIUM TUBERCULOSIS; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS; TUBERCULOSIS; VACCINES, DNA;

EID: 0030662575     PISSN: 03444325     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00870266     Document Type: Review

References (113)

1. Abou-Zeid C, Smith I, Grange JM, Ratliff TL, Steele J, Rook GAW (1988) The secreted antigens of Mycobacterium tuberculosis and their relationship to those recognized by the available antibodies. J Gen Microbiol 134 : 531
2. Adams E, Basten A, Rodda S, Britton WJ (1997) Human T-cell clones to the 70-kilodalton heat shock protein of Mycobacterium leprae define mycobacterium-specific epitopes rather than shared epitopes. Infect Immun 65 : 1061
3. Andersen AB (1994) Mycobacterium tuberculosis proteins - structure, function, and immunological relevance. Dan Med Bull 41 : 205
4. Andersen AB, Brennan P (1994) Proteins and antigens of Mycobacterium tuberculosis. In: Bloom BR (ed) Tuberculosis: pathogenesis, protection, and control. American Society for Microbiology, Washington, D.C., pp 307-332
5. Andersen P (1994) Effective vaccination of mice against Mycobacterium tuberculosis infection with a soluble mixture of secreted mycobacterial proteins. Infect Immun 62 : 2536
6. Andersen P (1994) The T cell response to secreted antigens of Mycobacterium tuberculosis. Immunobiology 191 : 537
7. Andersen P, Askgaard D, Ljungqvist L, Bennedsen J, Heron I (1991) Proteins released from Mycobacterium tuberculosis during growth. Infect Immun 59 : 1905
8. Andersen P, Askgaard D, Ljungqvist L, Bentzon MW, Heron I (1991) T-cell proliferative response to antigens secreted by Mycobacterium tuberculosis. Infect Immun 59 : 1558
9. Andersen P, Andersen AB, Sorensen AL, Nagai S (1995) Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice. J Immunol 154 : 3359
10. Anderton SM, Zee R van der, Noordzij A, Eden W van (1994) Differential mycobacterial 65-kDa heat shock protein T cell epitope recognition after adjuvant arthritis-inducing or protective immunization protocols. J Immunol 152 : 3656
11. Babiuk LA, Lewis PJ, Cox G, Drunen Littel-van den Hurk S van, Baca-Estrada M, Tikoo SK (1995) DNA immunization with bovine herpes virus-1 genes. Ann NY Acad Sci 772 : 47
12. Balasubramanian V, Wiegeshaus EH, Smith DW (1994) Mycobacterial infection in guinea pigs. Immunobiology 191 : 395
13. Barnes PF, Mehra V, Rivoire B, Fong SJ, Brennan PJ, Voegtline MS, Minden P, Houghten RA, Bloom BR, Modlin RL (1992) Immunoreactivity of a 10-kDa-antigen of Mycobacterium tuberculosis. J Immunol 148 : 1835
14. Barry MA, Lai WC, Johnston SA (1995) Protection against mycoplasma infection using expression-library immunization. Nature 377 : 632
15. Billingham MEJ, Carney S, Butler R, Colston MJ (1990) A mycobacterial 65-Kd heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic. J Exp Med 171 : 339
16. Birk OS, Douek DC, Elias D, Takacs K, Dewchand H, Gur SL, Walker MD, Zee R van der, Cohen IR, Altmann DM (1996) A role of Hsp60 in autoimmune diabetes: analysis in a transgenic model. Proc Natl Acad Sci USA 93 : 1032
17. Bloom BR, Fine PEM (1994) The BCG experience: implications for future vaccines against tuberculosis. In: Bloom BR (ed) Tuberculosis: pathogenesis, protection, and control. American Society for Microbiology, Washington, D.C., pp 531-557
18. Boesen H, Jensen BN, Wilcke T, Andersen P (1995) Human T-cell responses to secreted antigen fractions of Mycobacterium tuberculosis. Infect Immun 63 : 1491
19. Boom WH (1996) The role of T-cell subsets in Mycobacterium tuberculosis infection. Infect Agents Dis 5 : 73
20. Cheng SH, Walker KB, Lowrie DB, Mitchison DA, Swamy R, Datta M, Prabhakar R (1993) Monocyte antimycobacterial activity before and after Mycobacterium bovis BCG vaccination in Chingleput, India, and London, United Kingdom. Infect Immun 61 : 4501
21. Cirillo JD, Stover CK, Bloom BR, Jacobs WR, Bariella RG (1995) Bacterial vaccine vectors and Bacillus Calmette-Guerin. Clin Infect Dis 20: 1001
22. Cohen IR, Elias D (1996) Immunity to 60 kDa heat shock protein in autoimmune diabetes. Diabet Nutr Metab 9 : 229
23. Colditz GA, Berkey CS, Mosteller F, Brewer TF, Wilson ME, Burdick K, Fineberg HV (1998) The efficacy of bacillus Calmette-Guerin vaccination of newborns and infants in the prevention of tuberculosis: meta-analyses of the published literature. Pediatrics 96 : 29
24. Cole ST (1996) Why sequence the genome of Mycobacterium tuberculosis. Tuber Lung Dis 77 : 486
25. Collins FM (1991) Antituberculous immunity - new solutions to an old problem. Rev Infect Dis 13 : 940
26. Collins FM (1994) The immune response to mycobacterial infection: development of new vaccines. Vet Microbiol 40 : 95
27. Comstock GW (1994) Field trials of tuberculosis vaccines: How could we have done them better? Controlled Clin Trials 15 : 247
28. Converse PJ, Dannenherg AM, Estep JE, Sugisaki K, Abe Y, Schofield BH, Pitt MLM (1996) Cavitary tuberculosis produced in rabbits by aerosolized virulent tubercle bacilli. Infect Immun 64 : 4776
29. Croft M, Carter L, Swain SL, Dutton RW (1994) Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles. J Exp Med 180 : 1715
30. Dannenberg AM, Sugimoto M (1976) Liquefaction of caseous foci in tuberculosis. Am Rev Respir Dis 113 : 257
31. Davis HL, Michel ML, Mancini M, Schleef M, Whalen RG (1994) Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen. Vaccine 12 : 1503
32. Denagel DC, Pierce SK (1993) Heat shock proteins in immune responses. Crit Rev Immunol 13 : 71
33. de Wit D, Wootton M, Dhillon J, Mitchison DA (1995) The bacterial DNA content of mouse organs in the Cornell model of dormant tuberculosis. Tuber Lung Dis 76 : 555
34. Dolin PJ, Raviglione MC, Kochi A (1994) Global tuberculosis incidence and mortality during 1990-2000. Bull Who 72 : 213
35. Edwards KL, Goodrich JM, Muller D, Pollack A, Ziegler JE, Smith DW (1982) Infection with Mycobacterium avium-intracellulare and the protective effects of bacille Calmelle-Guerin. J Infect Dis 145 : 733
36. Fifis T, Costopoulos C, Radford AJ, Bacic A, Wood PR (1991) Purification and characterization of major antigens from a Mycobacterium bovis culture filtrate. Infect Immun 59 : 800
37. Fine PEM (1995) Bacille Calmelle-Guerin vaccines: a rough guide. Clin Infect Dis 20 : 11
38. Flynn JL, Goldstein MM, Triebold KJ, Koller B, Bloom BR (1992) Major histocompatibility complex class-I-restricted T-cells are required for resistance to Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 89 : 12013
39. Flynn JL, Chan J, Triebold KJ, Dalton DK, Stewart TA, Bloom BR (1993) An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J Exp Med 178 : 2249
40. Gulle H, Fray LM, Gormley EP, Murray A, Moriarty KM (1995) Responses of bovine T cells to fractionated lysate and culture filtrate proteins of Mycobacterium bovis BCG. Vet Immunol Immunopathol 48 : 183
41. Gupta LK, Bhatnagar S, Ram GC, Bansal MP (1995) Role of cytotoxic lymphocytes in immunity against bovine tuberculosis. Med Sci Res 23 : 535
42. Halpern MD, Kurlander RJ, Pisetsky DS (1996) Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha. Cell Immunol 167 : 72
43. Hart PDA, Sutherland I (1977) BCG and vole bacillus vaccines in the prevention of tuberculosis in adolescence and early adult life: final report to the Medical Research Council. Br Med J 2 : 293
44. Haslov K, Andersen AB, Ljungqvist L, Bentzon MW (1990) Comparison of the immunological activity of 5 defined antigens from Mycobacterium tuberculosis in 7 inbred guinea pig strains. Scand J Immunol 31 : 503
45. Haslov K, Andersen A, Nagai S, Gottschau A, Sorensen T, Andersen P (1995) Guinea pig cellular immune responses to proteins secreted by Mycobacterium tuberculosis. Infect Immun 63 : 804
46. Hassett DE, Whitton JL (1996) DNA immunization. Trends Microbiol 4 : 307
47. Havlir DV, Wallis RS, Boom WH, Daniel TM, Chervenak K, Ellner JJ (1991) Human immune response to Mycobacterium tuberculosis antigens. Infect Immun 59 : 665
48. Haynes JR, Fuller DH, Eisenbraun MD, Ford MJ, Pertmer TM (1994) Accell(R) particle-mediated DNA immunization elicits humoral, cytotoxic, and protective immune responses. AIDS Res Hum Retroviruses 10 : S43
49. HernandezPando R, Orozcoe H, Sampieri A, Pavon L, Velasquillo C, Larriva Sand J, Alcocer JM, Madrid MV (1996) Correlation between the kinetics of Th1/Th2 cells and pathology in a murine model of experimental pulmonary tuberculosis. Immunology 89 : 26
50. Horwitz MA, Lee BWE, Dillon BJ, Harth G (1995) Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis. Proc Natl Acad Sci USA 92 : 1530
51. Huygen K, Content J, Denis O, Montgomery DL, Yawman AM, Deck RR, DeWitt CM, Orme IM, Baldwin S, D'Souza C, Drowart A, Lozes E, Vandenbussche P, Van Vooren JP, Liu MA, Ulmer JB (1996) Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. Nature Med 2 : 893
52. Jacobs WR, Tuckman M, Bloom BR (1987) Introduction of foreign DNA into mycobacteria using a shuttle phasmid. Nature 327 : 532
53. Johnston SA, Tang DC (1994) Gene gun transfection of animal cells and genetic immunization. Methods Cell Biol 43 : 353
54. Kamala T, Paramasivan CN, Herbert D, Venkatesan P, Prabhakar R (1996) Immune response and modulation of immune response induced in the guinea-pigs by Mycobacterium avium complex (MAC) and M. fortuitum complex isolates from different sources in the south Indian BCG trial area. Indian J Med Res 103 : 201
55. Kaufmann SHE (1990) Heat shock proteins and the immune response. Immunol Today 11 : 129
56. Kaufmann SHE (1993) Immunity to intracellular bacteria. Annu Rev Immunol 11 : 129
57. Kingston AE, Hicks CA, Colston MJ, Billingham MEJ (1996) A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis. Clin Exp Immunol 103 : 77
58. Krieg AM (1996) An innate immune defense mechanism based on the recognition of CpG motifs in microbial DNA. J Lab Clin Med 128 : 128
59. Kumar V, Sercarz E (1996) Genetic vaccination: the advantages of going naked. Nature Med 2 : 857
60. Lagrange PH (1984) Cell-mediated immunity and delayed-type hypersensitivity. In: Kubica GP, Wayne LG (eds) The mycobacteria. A sourcebook. Dekker, New York, pp 681-720
61. Lecoeur H, Lagrange PH, Truffot C, Grosset J (1981) Microbial persistence and tuberculosis hypersensitivity after chemotherapy of the mouse experimental tuberculosis. Ann Immunol 132D : 237
62. Lee BY, Horwitz MA (1995) Identification of macrophage and stress-induced proteins of Mycobacterium tuberculosis. J Clin Invest 96 : 245
63. Lefford MJ, McGregor DD (1974) Immunological memory in tuberculosis. I. Influence of persisting viable organisms. Cell Immunol 14 : 417
64. Lim EM, Rauzier J, Timm J, Torrea G, Murray A, Gicquel B, Portnoi D (1995) Identification of Mycobacterium tuberculosis DNA sequences encoding exported proteins by using phoA gene fusions. J Bacteriol 177 : 59
65. Lowrie DB, Silva CL, Colston MJ, Ragno S, Tascon R (1997) Protection against tuberculosis by a plasmid DNA. Vaccine (in press)
66. Maes HH, Causse JE, Maes RF (1996) Mycobacterial infections: are the observed enigmas and paradoxes explained by immunosuppression and immunodeficiency? Med Hypotheses 46 : 163
67. Mehra V, Gong JH, Iyer D, Lin YG, Boylen CT, Bloom BR, Barnes PF (1996) Immune response to recombinant mycobacterial proteins in patients with tuberculosis infection and disease. J Infect Dis 174 : 431
68. Mendezsamperio P, Gonzalezgarcia L, Pinedafragoso PR, Ramossanchez E (1995) Specificity of T cells in human resistance to Mycobacterium tuberculosis infection. Cell Immunol 162 : 194
69. Monahan IM, Banerjee DK, Jacobs WR, Butcher PD (1996) Gene expression of Mycobacterium bovis BCG during interaction with macrophages. Abstracts of the 3rd International Conference on the Pathogenesis of Mycobacterial Diseases, 27-30 June, Stockholm. Swedish Institute for Infections Disease Control, Stockholm, abstr. no. 43
70. Murray PJ, Young RA (1992) Stress and immunological recognition in host-pathogen interactions. J Bacteriol 174 : 4193
71. Nomoto K, Yoshikai Y (1991) Heat-shock proteins and immunopathology - regulatory role of heat-shock protein-specific T-cells. Springer Semin Immunopathol 13 : 63
72. Oftung F, Mustafa AS, Husson R, Young RA, Godal T (1987) Human T cell clones recognise two abundant Mycobacterium tuberculosis protein antigens expressed in Escherichia coli. J Immunol 138 : 927
73. Onyebujoh PC, Abdulmumini T, Robinson S, Rook GAW, Stanford JL (1995) Immunotherupy with Mycobacterium vaccae as an addition to chemotherapy for the treatment of pulmonary tuberculosis under difficult conditions in Africa. Respir Med 89 : 199
74. Orme IM, Collins FM (1984) Efficacy of Mycobacterium bovis BCG vaccination in mice undergoing prior pulmonary infection with atypical mycobacteria. Infect Immun 44 : 28
75. Orme IM, Andersen P, Boom WH (1993) T-cell response to Mycobacterium tuberculosis. J Infect Dis 167 : 1481
76. Pal PG, Horwitz MA (1992) Immunization with extracellular proteins of Mycobacterium tuberculosis induces cell-mediated immune responses and substantial protective immunity in a guinea pig model of pulmonary tuberculosis. Infect Immun 60 : 4781
77. Palmer CE, Long MW (1966) Effects of infection with atypical mycobacteria on BCG vaccination and tuberculosis. Am Rev Respir Dis 94 : 553
78. Prakken ABJ, Eden W van, Rijkers GT, Kuis W, Toebes EA, DeGraeff Meeder ER, Zee R van der, Zegers BJM (1996) Autoreactivity to human heat-shock protein 60 predicts disease remission in oligoarticular juvenile rheumatoid arthritis. Arthritis Rheum 39 : 1826
79. Ragno S, Colston MJ, Lowrie DB, Winrow VR, Blake DR, Tascon R (1997) Immunization with naked DNA encoding mycobacterial hsp65 protects rats from adjuvant arthritis. Arthritis Rheum (in press)
80. Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, Swain SL, Spiegelberg HL, Carson DA (1996) Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci USA 93 : 5141
81. Reiner NE (1994) Altered cell signaling and mononuclear phagocyte deactivation during intracellular infection. Immunol Today 15 : 374
82. Robertson JS (1996) The potential of DNA vaccines. J Biotech Healthcare 3 : 239
83. Rodrigues LC, Diwan VK, Wheeler JG (1993) Protective effect of BCG against tuberculosis meningitis and miliary tuberculosis: a meta-analysts. Int J Epidemiol 22 : 1154
84. Rook GAW, Hernandez Pando R (1994) T cell helper types and endocrines in the regulation of tissue-damaging mechanisms in tuberculosis. Immunobiology 191 : 478
85. + T cells in chronic infections - an immunoendocrinological hypothesis not exclusive to HIV. Immunol Today 14 : 568
86. Russell WR, Pollock JM, Butcher PD, Hewinson RG (1996) The detection of M. bovis antigens expressed inside macrophages. Proceedings of the 2nd International Conference on Mycobacterium bovis: Tuberculosis in wildlife and domestic animals: 1996 Otago conference. University of Otago Press, Dunedin, pp 135-138
87. Sander B, Skansen Saphir U, Damm O, Hakansson L, Andersson J, Andersson U (1995) Sequential production of Th1 and Th2 cytokines in response to live bacillus Calmette-Guerin. Immunology 86 : 512
88. + T cells. Annu Rev Immunol 12 : 635
89. Siegrist CA, Lambert PH (1996) DNA vaccines: what can we expect? Infect Agents Dis 5 : 55
90. Silva CL, Lowrie DB (1994) A single mycobacterial protein (hsp65) expressed by a transgenic antigen-presenting cell vaccinates mice against tuberculosis. Immunology 82 : 244
91. Silva CL, Silva MF, Pietro RCLR, Lowrie DB (1994) Protection against tuberculosis by passive transfer with T-cell clones recognizing mycobacterial heat-shock protein 65. Immunology 83 : 341
92. Silva CL, Pietro RLR, Januario A, Bonato VLD, Lima VMF, DaSilva MF, Lowrie DB (1995) Protection against tuberculosis by bone marrow cells expressing mycobacterial hsp65. Immunology 86 : 519
93. Silva CL, Silva MF, Pietro RCLR, Lowrie DB (1996) Characterization of T cells that confer a high degree of protective immunity against tuberculosis in mice after vaccination with tumor cells expressing mycobacterial hsp65. Infect Immun 64 : 2400
94. Smith PG (1994) BCG vaccination. In: Davies PDO (ed) Clinical tuberculosis. Chapman and Hall, London, pp 297-310
95. Sorensen AL, Nagai S, Houen G, Andersen P, Andersen AB (1995) Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect Immun 63 : 1710
96. Springett VH, Sutherland I (1990) BCG vaccination of school children in England and Wales. Thorax 45 : 83
97. Stanford JL, Rook GAW (1983) Environmental mycobacteria and immunization with BCG. In: Easmon CSF, Jeljaszewicz J (eds) Medical microbiology, vol 2; Immunization against bacterial disease. Academic Press, London, pp 43-69
98. Stanford JL, Stanford CA (1994) Immunotherapy of tuberculosis with Mycobacterium vaccae NCTC 11659. Immunobiology 191 : 555
99. Tantimavanich S, Nagai S, Nomaguchi H, Kinomoto M, Ohara N, Yamada T (1993) Immunological properties of ribosomal proteins from Mycobacterium bovis BCG. Infect Immun 61 : 4005
100. Tascon RE, Colston MJ, Ragno S, Stavropoulos E, Gregory D, Lowrie DB (1996) Vaccination against tuberculosis by DNA injection. Nature Med 2 : 888
101. Tsukaguchi K, Balaji KN, Boom WH (1995) CD4(+) α β T cell and γ δ T cell responses to Mycobacterium tuberculosis - Similarities and differences in Ag recognition, cytotoxic effector function, and cytokine production. J Immunol 154 : 1786
102. Van Eden W, Anderton SM, Zee R van der, Prakken ABJ, Rijkers GT (1995) Specific immunity as a critical factor in the control of autoimmune arthritis: the example of hsp60 as an ancillary and protective autoantigen. Scand J Rheumatol 101 : 141
103. Walsh GP, Tan EV, delaCruz EC, Abalos RM, Villahermosa LG, Young LJ, Cellona RV, Nazareno JB, Horwitz MA (1996) The Philippine cynomolgus monkey (Macaca fascicularis) provides a new non-human primate model of tuberculosis that resembles human disease. Nature Med 2 : 430
104. Wiegeshaus EH, Harding G, McMurray D, Grover AA, Smith DW (1971) A cooperative evaluation of lest systems used to assay tuberculosis vaccines. Bull WHO 45 : 543
105. Wiker HG, Nagai S, Harboe M, Ljungqvist L (1992) A family of cross-reacting proteins secreted by Mycobacterium tuberculosis. Scand J Immunol 36 : 307
106. Wolffe JA, Ludtke JJ, Acsadi G, Williams P, Jani A (1992) Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle. Hum Mol Genet 1 : 363
107. Yamamura M, Wang XH, Ohmen JD, Uyemura K, Rea TH, Bloom BR, Modlin RL (1992) Cytokine patterns of immunologically mediated tissue damage. J Immunol 149 : 1470
108. Youmans AS, Youmans GP (1965) Immunogenic activity of a ribosomal fraction obtained from Mycobacterium tuberculosis. J Bacteriol 89 : 1291
109. Young DB, Kaufmann SHE, Hermans PWM, Thole JER (1992) Mycobacterial protein antigens. - A compilation. Mol Microbiol 6 : 133
110. Young RA (1990) Stress proteins and immunology. Annu Rev Immunol 8 : 401
111. Young RA, Elliott TJ (1989) Stress proteins, infection, and immune surveillance. Cell 59 : 5
112. Yuan Y, Crane DD, Barry CE (1996) Stationary phase-associated protein expression in Mycobacterium tuberculosis: function of the mycobacterial α-crystallin homolog. J Bacteriol 178 : 4484
113. Zhu X, Venkataprasad N, Thangaraj H, Vordermeier HM (1996) Nucleic acid vaccination for protection against M. tuberculosis. Abstracts of the 3rd International Conference on the Pathogenesis of Mycobacterial Infections. 27-30 June, Stockholm. Swedish Institute for Infections Disease Control, Stockholm, abstr. no. 25