Ca2+ binding to the first epidermal growth factor-like domain of human blood coagulation factor IX promotes enzyme activity and factor VIII light chain binding

Journal of Biological Chemistry

Volumn 271, Issue 41, 1996, Pages 25332-25337

  Lenting, Peter J ^a   Christophe, Olivier D ^a   Maat, Hans Ter ^a   Jasper G Rees, D ^b   Mertens, Koen ^a  

^a CENTRAL LABORATORY   (Netherlands)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; BLOOD CLOTTING FACTOR 9A; CALCIUM; EPIDERMAL GROWTH FACTOR; MAGNESIUM; MONOCLONAL ANTIBODY; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN;

ARTICLE; BINDING AFFINITY; BLOOD CLOTTING; CALCIUM BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE MUTATION; HUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; DOG; GENETIC TRANSFECTION; IMMUNOLOGY; ISOLATION AND PURIFICATION; KIDNEY; KINETICS; MACROMOLECULE; METABOLISM; MOLECULAR GENETICS; SITE DIRECTED MUTAGENESIS; SYNTHESIS;

FELIS CATUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CALCIUM; CELL LINE; DOGS; EPIDERMAL GROWTH FACTOR; FACTOR IX; FACTOR VIII; HUMANS; KIDNEY; KINETICS; MACROMOLECULAR SUBSTANCES; MAGNESIUM; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 0029661981     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.41.25332     Document Type: Article

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