Serum leptin and weight reduction in female obesity

European Journal of Endocrinology

Volumn 135, Issue 6, 1996, Pages 659-662

  Geldszus, R ^a   Mayr, B ^a   Horn, R ^a   Geisthovel F ^b   Von Zur Muhlen A ^a   Brabant, G ^a,c  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Inst Gynaecological Endocrinol R   (Germany)

^c Abt Klin Endokrinol Med H   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN;

ARTICLE; CONTROLLED STUDY; DIET; ENERGY EXPENDITURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RADIOIMMUNOASSAY; WEIGHT REDUCTION;

EID: 0030498034     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1350659     Document Type: Article

References (31)

1. Mrosovsky N. Body fat: what is regulated. Physiol Behav 1986;38:407-14
2. Weigle DS. Appetite and the regulation of body composition. FASEB J 1994;8:302-10
3. Barinaga M, "Obese" protein slims mice. Science 1995;269:475-6
4. Fredrich RC, Löllmann B, Hamann A, Napolitano-Rosen A, Kahn BB, et al. Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity. J Clin Invest 1995;96:1658-63
5. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JAM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-32
6. Masuzaki H, Ogawa Y, Isse N, Satoh N, Okazaki T, et al. Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue. Diabetes 1995;44:855-8
7. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, et al. Effects of the obese gene product on body weights regulation on ob/ob mice. Science 1995;269:540-3
8. Halaas JL, Gajiwqala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 1995;269:543-6
9. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. Recombinant mouse ob protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 1995;269:546-9
10. Stephens TW, Basinski M, Bristow PK, Bue-Valleskey JM, Burgett SG, Craft L, et al. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 1995;377: 530-2
11. Weigle D, Bukowski TR, Foster DC, Holderman S, Kramer JM, Lasser G, et al. Recombinant ob protein reduces feeding and body weight in the ob/ob mouse. J Clin Invest 1995;96:2065-70
12. Chen H, Charlat O, TartagliaLA, Woolf EA, Weng X, Ellis SJ, et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996;84:491-5
13. Lee G, Proenca R, Montez, Carroll KM, Darvishzadeh JG, Lee JI, et al. Abnormal splicing of the leptin receptor in diabetic mice. Nature 1996;379:632-5
14. Considine RV, Considene EL, Williams CJ, Nyce MR, Magosin SA, Bauer TL, et al. Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity. J Clin Invest 1995;95:2986-8
15. Lönnquist F, Arner P, Norfors L, Schalling M. Overexpression of the obese (ob) gene in adipose tissue of human obese subjects. Nature Med 1995;1:950-3
16. Hamilton BS, Paglia D,Kwan AYM, Deitel M. Increased obese mRNMA expression in omental fat cells from massively obese humans. Nature Med 1995;1:953-6
17. Considine RV, Sinha MK, Heiman ML, Kriauciunnas A, Stephens TW, Nyce MR. et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996;334:292-5
18. Horn R, Geldszus R, Pötter E, von zur Mühlen A, Brabant G. Radioimmunoassay for the detection of leptin in human serum. Exp Clin Endocrinol Diab 1996. In press
19. Maffei M, Halaas J, Ravussin E, Prately RE, Lee GH, Shang Y, et al. Leptin levels in human and rodents: Measurement of plasma leptin and ob RNA in obese and weight reduced subjects. Nature Med 1995;1:1155-61
20. Schwartz MW, Peskind E, Raskin E, Boyko EJ, Porte D. Cerebrospinal fluid leptin levels: relationship to plasma levels and adiposity in humans. Nature Med 1996;2:589-92
21. Hannan WJ, Wrate RM, Cowen SJ, Freeman CP. Body mass index as an estimate of body fat. Int J Eat Dis 1995;18:91-7
22. Rentsch J, Levens N, Chiesi M. Recominant ob-gene product reduces food intake in fasted mice. Biochem Biohys Res Commun 1995;214:131-6
23. Tataglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R. et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 1995;83:1263-71
24. NIH Technology Assessment Conference Panel. Methods for voluntary weight loss and control. Ann Intern Med 1992;116:942-6
25. Phillips MS, Liu QY, Hammond HA, Dugan V, Hey PJ, Caskey CT, et al. Leptin receptor missense mutation in the fatty zucker rat. Nature Gen 1996;13:18- 9
26. Dagogojack S, Fanelli C, Paramore D, Brothers J, Landt M. Plasma leptin and insulin relationships in obese and nonobese humans. Diabetes 1996;45:695-8
27. Kolaczynski JW, Nyce MR, Considine RV, Boden G, Nolan JJ, Henry R, et al. Acute and chronic effect of insulin on leptin production in humans - studies in vivo and in vitro. Diabetes 1996;45:699-701
28. Maffei M, Stoffel M, Barone M, Moon B, Dammerman M, Ravussin E, et al. Absence of mutations in the human ob gene in obese/ diabetic subjects. Diabetes 1996;45:679-82
29. Houseknecht K, Flier S, Frevert EU, Fredrich RC, Flier JS, Kahn BB. Leptin secretion correlates with adipocte size in genetic and dietary obesity. Diabetes 1996;45 Suppl 2:41A
30. DeVos P, Saladin R, Auwerx J, Staels B. Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J Biol Chem 1995;270:15958-61
31. Cusin I, Sainsbury A, Doyle P, Rohner-Jeanrenaud F, Jeanrenaud B. The ob gene and insulin. A relationship leading to clues in the understanding of obesity. Diabetes 1995;44:1467-70