Initial characterization of autoprocessing and active-center mutants of CMV proteinase

Journal of Protein Chemistry

Volumn 15, Issue 8, 1996, Pages 763-774

  Snyder, S W ^a   Edalji, R P ^a   Lindh, F G ^a   Walter, K A ^a   Solomon, L ^a   Pratt, S ^a   Steffy, K ^a   Holzman, T F ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

calorimetry; CMV; Cytomegalovirus proteinase; mutant; ultracentrifugation

Indexed keywords

PROTEINASE; VIRUS PROTEIN;

ARTICLE; CYTOMEGALOVIRUS; DIFFERENTIAL SCANNING CALORIMETRY; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; CALORIMETRY, DIFFERENTIAL SCANNING; CELL DIVISION; CIRCULAR DICHROISM; CLONING, MOLECULAR; CYTOMEGALOVIRUS; ENZYME STABILITY; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; ULTRACENTRIFUGATION; VIRAL PROTEINS;

CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; ESCHERICHIA COLI; HUMAN HERPESVIRUS 5; MIRIDAE;

EID: 0030458090     PISSN: 02778033     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01887151     Document Type: Article

References (23)

1. Baum, E. Z., Bebernitz, G. A., Hulmes, J. D., Muzithras, V. P., Jones, T. R., and Gluzman, Y. (1993). J. Virol. 67, 497-506.
2. Baum, E. Z., Siegel, M. M., Bebernitz, G. A., Hulmes, J. D., Sridharan, L., Sun, L., Tabei, K., Johnston, S. H., Wildey, M. J., Nygaard, J., Jones, T. R., and Gluzman, Y. (1996a). Biochemistry 36, 5838-5846.
3. Baum, E. Z., Dong, W.-D., Siegel, M. M., Hulmes, J., Bebernitz, G. A., Sridharan, L., Tabei, K., Krishnamurthy, G., Carofiglio, T., Groves, J. T., Bloom, J. D., DiGrandi, M., Bradley, M., Ellestad, G., Seddon, A. P., and Gluzman, Y. (1996b). Biochemistry 36, 5847-5855.
4. Burck, P. J., Berg, D. H., Luk, T. P., Sassmannshausen, L. M., Wakulchik, M., Smith, D. P., Hsiung, H. M., Becker, G. W., Gibson, W., and Villarreal, E. C. (1994). J. Virol. 68, 2937-2946.
5. Chee, M. S., Bankier, A. T., Beck, S., Bohni, R., Brown, C. M., Cerney, R., Horsnell, T., Hutchison III, C. A., Kouzarides, T., Martignetti, J. A., Preddie, E., Satchwell, S. C., Tomlinson, P., Weston, K. M., and Barrell, B. G. (1990). Curr. Top. Microbiol. Immunol. 154, 125-169.
6. Cox, G. A., Wakulchik, M., Sassmannshausen, L. M., Gibson, W., and Villarreal, E. C. (1995). J. Virol. 69, 4524-4528.
7. Darke, P. L., Cole, J. L., Waxman, L., Hall, D. L., Sardana, M. K., and Kuo, L. C. (1996). J. Biol. Chem. 271, 7445-7449.
8. Deléage, G., and Geourjon, C. (1993). CABIOS 9, 197-199.
9. Donovan, J. W. (1984). TIBS 9, 340-344.
10. Fujita, H. (1962). Mathematical Theory of Sedimentation Analysis, Academic Press, New York, pp. 64-122.
11. Fujita, H. (1975). Foundations of Ullracentrifugal Analysis, John Wiley & Sons, New York, pp. 64-81.
12. Hall, M., and Gibson, W. (1996). J. Virol. 70, 5395-5404.
13. Holwerda, B. C, Wittwer, A. J., Duffin, K. L., Smith, C., Toth, M. V., Carr, L. S., Wiegand, R. C, and Bryant, M. L. (1994). J. Biol. Chem. 269, 25911-25919.
14. Holzman, T. F., and Snyder, S. W. (1994). In Modern Analytical Ultracentrifugation: Acquisition and Interpretation of Data for Biological and Synthetic Polymer Systems (Schuster, T. M., and Laue, T. M., eds.), Birkhauser, Boston, pp. 298-314.
15. Jones, T. R., Sun, L., Bebernitz, G. A., Muzithras, V. P., Kim, H.-J., Johnston, S. H., and Baum, E. Z. (1994). J. Virol. 68, 3742-3752.
16. Kunkel, T., Roberts, D., and Zakour, R. (1987). Meth. Emzymol. 54, 367-382.
17. Margosiak, S. A., Vanderpool, D. L., Sisson, W., Pinko, C., and Kan, C.-C. (1996). Biochemistry 35, 5300-5307.
18. McRoric, D. K., and Marque, J. (1995). Bull. Am. Phys. Soc. Abst. D34.42.
19. O'Boyle II, D. R., Wager-Smith, K., Stevens III, J. T., and Weinheimer, S. P. (1995). J. Biol. Chem. 270, 4753-4758.
20. Pinko, C, Margosiak, S. A., Vanderpool, D., and Gutowski, J. C. (1995). J. Biol. Chem. 270, 23634-23640.
21. Stevens, J. T., Mapelli, C, Tsao, J., Hail, M., O'Boyle II, D., Weinheimer, S. P., and Duanni, C. L. (1994). Eur. J. Biochem. 226, 361-367.
22. Welch, A. R., Woods, A. S., McNally, L. M., Cotter, R. J., and Gibson, W. (1991). Proc. Natl. Acad. Sci. USA 88, 10792-10796.
23. Yang, J. T., Wu, C.-S. C., and Martinez, H. M. (1986). Meth. Enzymol. 130, 208-269.