메뉴 건너뛰기




Volumn 3, Issue 11, 1996, Pages 863-867

Telomerase: Anti-cancer target or just a fascinating enzyme?

Author keywords

[No Author keywords available]

Indexed keywords


EID: 0030292846     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(96)90173-8     Document Type: Review
Times cited : (26)

References (32)
  • 2
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim, N.W., et al., & Shay, J.W. (1994), Specific association of human telomerase activity with immortal cells and cancer. Science 266, 2011-2015.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Shay, J.W.2
  • 5
    • 0028201293 scopus 로고
    • Activation of telomerase in a human tumor
    • de Lange, T. (1994). Activation of telomerase in a human tumor. Proc. Natl. Acad. Sci. USA 91, 2882-2885.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2882-2885
    • De Lange, T.1
  • 6
    • 0029075066 scopus 로고
    • Telomeres, telomerase, and immortality
    • Rhyu, M.S. (1995). Telomeres, telomerase, and immortality. J. Natl. Cancer Inst. 87, 884-894.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 884-894
    • Rhyu, M.S.1
  • 7
    • 0011864960 scopus 로고
    • The telomerase-cancer connection: Will exceptions make a new rule?
    • Ezzel, C. (1995). The telomerase-cancer connection: will exceptions make a new rule? J. NIH Res. 7, 41-45.
    • (1995) J. NIH Res. , vol.7 , pp. 41-45
    • Ezzel, C.1
  • 8
    • 0029895383 scopus 로고    scopus 로고
    • Refining the telomere-telomerase hypothesis of aging and cancer
    • Holt, S.E., Shay, J.W. & Wright, W.E. (1996). Refining the telomere-telomerase hypothesis of aging and cancer. Nature Biotechnol. 14, 836-839.
    • (1996) Nature Biotechnol. , vol.14 , pp. 836-839
    • Holt, S.E.1    Shay, J.W.2    Wright, W.E.3
  • 10
    • 0029156035 scopus 로고
    • Telomere shortening is associated with cell division in vitro and in vivo
    • Allsopp, R.C., et al., & Harley, C.B. (1995). Telomere shortening is associated with cell division in vitro and in vivo. Exp. Cell Res. 220, 194-200.
    • (1995) Exp. Cell Res. , vol.220 , pp. 194-200
    • Allsopp, R.C.1    Harley, C.B.2
  • 11
    • 0025115349 scopus 로고
    • Structure and variability of human chromosome ends
    • de Lange, T., et al., & Varmus, H.E. (1990). Structure and variability of human chromosome ends. Mol. Cell Biol. 10, 518-527
    • (1990) Mol. Cell Biol. , vol.10 , pp. 518-527
    • De Lange, T.1    Varmus, H.E.2
  • 12
    • 0029128798 scopus 로고
    • Telomerase and DNA end replication: No longer a lagging strand problem?
    • Lingner, J., Cooper, J.P. & Cech, T.R. (1995). Telomerase and DNA end replication: no longer a lagging strand problem? Science 269, 1533-1524,
    • (1995) Science , vol.269 , pp. 1533-11524
    • Lingner, J.1    Cooper, J.P.2    Cech, T.R.3
  • 13
    • 0022402513 scopus 로고
    • Identification of a specific telomere transferase activity in Tetrahymena extracts
    • Greider, C.W. & Blackburn, E.H. (1985). Identification of a specific telomere transferase activity in Tetrahymena extracts. Cell 43, 405-413.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 14
    • 0025021235 scopus 로고
    • Functional evidence for an RNA template in telomerase
    • Shippen-Lentz, D. & Blackburn E.H. (1990) Functional evidence for an RNA template in telomerase. Science 247, 546-552.
    • (1990) Science , vol.247 , pp. 546-552
    • Shippen-Lentz, D.1    Blackburn, E.H.2
  • 15
    • 0028990123 scopus 로고
    • Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme
    • Collins, K., Kobayashi, R. & Greider, C.W. (1995). Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme. Cell 81, 677-686.
    • (1995) Cell , vol.81 , pp. 677-686
    • Collins, K.1    Kobayashi, R.2    Greider, C.W.3
  • 16
    • 0029938746 scopus 로고    scopus 로고
    • Structure and function of telomerase
    • Collins, K. (1996). Structure and function of telomerase. Curr. Opin. Cell Biol. 8, 374-380.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 374-380
    • Collins, K.1
  • 17
    • 0029096515 scopus 로고
    • The RNA component of human telomerase
    • Feng, J., et al., & Villeponteau, B. (1995). The RNA component of human telomerase. Science 269, 1236-1239.
    • (1995) Science , vol.269 , pp. 1236-1239
    • Feng, J.1    Villeponteau, B.2
  • 18
    • 0025808098 scopus 로고
    • Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase
    • Morin, G.B. (1991). Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase. Nature 353, 454-456.
    • (1991) Nature , vol.353 , pp. 454-456
    • Morin, G.B.1
  • 19
    • 0029066169 scopus 로고
    • Telomerase activity in normal and malignant hematopoietic cells
    • Broccoli, D., Young, J.W. & de Lange, T. (1995). Telomerase activity in normal and malignant hematopoietic cells. Proc. Natl. Acad. Sci. USA 92, 9082-9086.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9082-9086
    • Broccoli, D.1    Young, J.W.2    De Lange, T.3
  • 20
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • Bryan, T.M., Engelzou, A., Gupta, J., Bachetti, S. & Reddel, R.R. (1995). Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J. 14, 4240-4248.
    • (1995) EMBO J. , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Engelzou, A.2    Gupta, J.3    Bachetti, S.4    Reddel, R.R.5
  • 22
    • 0027266758 scopus 로고
    • An alternative pathway for yeast telomere maintenance rescues est1 senescence
    • Lunblad, V. & Blackburn, E.H. (1993). An alternative pathway for yeast telomere maintenance rescues est1 senescence. Cell 73, 347-360.
    • (1993) Cell , vol.73 , pp. 347-360
    • Lunblad, V.1    Blackburn, E.H.2
  • 23
    • 0026336532 scopus 로고
    • Gerontology as oncology. Research on aging as the key to the understanding of cancer
    • Miller, R.A. (1991). Gerontology as oncology. Research on aging as the key to the understanding of cancer. Cancer 68, 2496-2501.
    • (1991) Cancer , vol.68 , pp. 2496-2501
    • Miller, R.A.1
  • 24
    • 0028875212 scopus 로고
    • Increased telomerase activity in mouse skin premalignant progression
    • Bednarek, A., Budursova, I., Slaga, T.J. & Aldaz, C.M. (1995). Increased telomerase activity in mouse skin premalignant progression. Cancer Res. 55, 4566-4569.
    • (1995) Cancer Res. , vol.55 , pp. 4566-4569
    • Bednarek, A.1    Budursova, I.2    Slaga, T.J.3    Aldaz, C.M.4
  • 25
    • 0029941676 scopus 로고    scopus 로고
    • Telomerase activation in mouse mammary tumors: Lack of detectable telomere shortening and evidence for regulation of telomerase RNA and cell proliferation
    • Broccoli, D., Godley, L.A., Donehower, L.A., Varmus, H.E. & de Lange, T. (1996). Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA and cell proliferation. Mol. Cell Biol. 16, 3765-3772.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 3765-3772
    • Broccoli, D.1    Godley, L.A.2    Donehower, L.A.3    Varmus, H.E.4    De Lange, T.5
  • 26
    • 0030070054 scopus 로고    scopus 로고
    • Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis
    • Blasco, M.A., Rizen, M., Greider, C.W. & Hanahan, D. (1996). Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis. Nature Genet. 12, 200-204.
    • (1996) Nature Genet. , vol.12 , pp. 200-204
    • Blasco, M.A.1    Rizen, M.2    Greider, C.W.3    Hanahan, D.4
  • 27
    • 0029154735 scopus 로고
    • Functional characterization and developmental regulation of mouse telomerase RNA
    • Blasco, M., Funk, W., Villeponteau, B. & Greider, C.W. (1995). Functional characterization and developmental regulation of mouse telomerase RNA. Science 269, 1267-1270.
    • (1995) Science , vol.269 , pp. 1267-1270
    • Blasco, M.1    Funk, W.2    Villeponteau, B.3    Greider, C.W.4
  • 29
    • 0028222581 scopus 로고
    • The effect of nucleoside analogs on telomerase and telomeres in Tetrahymena
    • Strahl, C. & Blackburn, E.H. (1994). The effect of nucleoside analogs on telomerase and telomeres in Tetrahymena. Nucleic Acids Res, 22, 893-900.
    • (1994) Nucleic Acids Res , vol.22 , pp. 893-900
    • Strahl, C.1    Blackburn, E.H.2
  • 30
    • 0029655485 scopus 로고    scopus 로고
    • Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines
    • Strahl, C. & Blackburn, E.H. (1996). Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines. Mol. Cell Biol. 16, 63-65.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 63-65
    • Strahl, C.1    Blackburn, E.H.2
  • 31
    • 0025944831 scopus 로고
    • A conserved secondary structure for telomerase RNA
    • Romero, D.P. & Blackburn, E.H. (1991). A conserved secondary structure for telomerase RNA. Cell, 67, 343-353.
    • (1991) Cell , vol.67 , pp. 343-353
    • Romero, D.P.1    Blackburn, E.H.2
  • 32
    • 0028029818 scopus 로고
    • Architecture of telomerase RNA
    • Bhattacharyya, A. & Blackburn, E.H. (1994). Architecture of telomerase RNA. EMBO J. 13, 5721-5731.
    • (1994) EMBO J. , vol.13 , pp. 5721-5731
    • Bhattacharyya, A.1    Blackburn, E.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.