The window of opportunity for fetal gene therapy

Molecular Human Reproduction

Volumn 2, Issue 7, 1996, Pages 472-474

  Iwamoto, Harriet S ^a,b  

^a UNIVERSITY OF CINCINNATI   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; FEMALE; FETUS DISEASE; GENE THERAPY; HUMAN; METHODOLOGY; PREGNANCY;

ANIMALS; FEMALE; FETAL DISEASES; GENE THERAPY; HUMANS; PREGNANCY;

EID: 0030178032     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/2.7.472     Document Type: Short Survey

References (38)

1. Altshuler, G. (1974) Immunologic competence of the immature human fetus. Morphologic evidence from intrauterine Cytomegalovirus infection. Obstet. Gynecol., 43, 811-816.
2. Altshuler, G. and McAdams, A.J. (1971) Cytomegalic inclusion disease of a nineteen-week fetus. Am. J. Obstet. Gynecol., 111, 295-298.
3. Billingham, R.E., Brent, L. and Medawar, P.B. (1953) 'Actively acquired tolerance' of foreign cells. Nature, 172, 603-606.
4. Buckley, R.H. (1996) Allergy, immunology, and rheumatology. In Rudolph, A.M., Hoffman, J.I.E. and Rudolph, C.D. (eds.), Rudolph's Pediatrics, 20th edn. Appleton and Lange, Stamford, CT, pp. 431-437.
5. Crombleholme, T.M. and Bianchi, D.W. (1994) In utero hematopoietic stem cell transplantation and gene therapy. Semin. Perinatol., 18, 376-384.
6. D'Alton, M.E. (1994) Prenatal diagnostic procedures. Semin. Perinatol., 18, 140-162.
7. Dosch, H.-M., Hui, M.F. and Doherty, P.J. (1993) Development of normal and abnormal immune functions in humans. In Cooper, E.L. and Nisbet-Brown, E. (eds.), Developmental Immunology. Oxford University Press, Oxford, pp. 452-470.
8. Edwards, R.G., Jauniaux, E., Binns, R.M. et al. (1995) Induced tolerance and chimaerism in human fetuses using coelocentesis: a medical opportunity to avert genetic disease? Hum. Reprod. Update, 1, 419-427.
9. Fahey, K.J. and Morris, B. (1978) Humoral immune responses in fetal sheep. Immunology, 35, 651-661.
10. Flake, A.W., Harrison, M.R., Adzick, N.S. et al. (1986) Transplantation of fetal hematopoietic stem cells in utero: the creation of hematopoietic chimeras. Science, 233, 776-778.
11. Flake, A.W., Harrison, M.R. and Zanjani, E.D. (1991) In utero stem cell transplantation. Exp. Hematol., 19, 1061-1064.
12. Forsthuber, T., Yip, H.C. and Lehmann, P.V. (1996) Induction of TH1 and TH2 immunity in neonatal mice. Science, 271, 1728-1730.
13. 2-macroglobulin, and prealbumin in the human conceptus. J. Clin. Invest., 48, 1433-1446.
14. Guzman, R.J., Lemarchand, P., Crystal, R.G. et al. (1993) Efficient gene transfer into myocardium by direct injection of adenovirus vectors. Circ. Res., 73, 1202-1207.
15. Harrison, M.R., Slotnick, R.N., Crombleholme, T.M. et al. (1989) In utero transplantation of fetal liver haemopoietic stem cells in monkeys. Lancet, ii, 1425-1427.
16. Haynes, B.F. and Denning, S.M. (1994) Lymphopoiesis. In Stamatoyannopoulos, G., Nienhuis, A.W., Majerus, P.W. and Varmus, H. (eds.), The Molecular Basis of Blood Diseases, 2nd edn. W.B.Saunders Co., Philadelphia, pp. 425-462.
17. Hedrick, M.H., Rice, H.E., MacGillivray, T.E. et al. (1994) Hematopoietic chimerism achieved by in utero hematopoietic stem cell injection does not induce donor-specific tolerance for renal allografts in sheep. Transplantation, 58, 110-111.
18. Holzinger, A., Trapnell, B.C., Weaver, T.E. et al. (1995) Intraamniotic administration of an adenoviral vector for gene transfer to fetal sheep and mouse tissues. Pediatr. Res., 38, 1-7.
19. Kelemen, E. and Janossa, M. (1980) Macrophages are the first differentiated blood cells formed in human embryonic liver. Exp. Hematol., 8, 996-1000.
20. LePage, F. and Schramm, P. (1958) Aspects histologiques du placenta et des membranes dans la maladies des inclusions cytomegaliques. Gynecol. Obstet., 57, 273-279.
21. McCray, P.B., Jr, Armstrong, K., Zabner, J. et al. (1995) Adenoviral-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo. J. Clin. Invest., 95, 2620-2632.
22. Niederhuber, J.E., Shermeta, D., Turcotte, J.G. et al. (1971) Kidney transplantation in the fetal Iamb. Transplantation, 12, 161-166.
23. Nossal, G.J.V. (1957) The immunological response of fetal mice to influenza virus. Aust. J. Exp. Biol., 35, 549-558.
24. Pitt, B.R. and Robbins, P.D. (1996) Retrovirus-mediated gene therapy to fetal lung. Mol. Hum. Reprod., 2, in press.
25. Pitt, B.R., Schwarz, M.A., Pilewski, J.M. et al. (1995) Retrovirus-mediated gene transfer in lungs of living fetal sheep. Gene Therapy, 2, 344-350.
26. Ridge, J.P., Fuchs, E.J. and Matzinger, P. (1996) Neonatal tolerance revisited: turning on newborn T cells with dendritic cells. Science, 271, 1723-1726.
27. Sarzotti, M., Robbins, D.S. and Hoffman, P.M. (1996) Induction of protective CTL responses in newborn mice by a murine retrovirus. Science, 271, 1726-1728.
28. Schinckel, P.G. and Ferguson, K.A. (1953) Skin transplantation in the fetal lamb. Aust. J. Biol. Sci., 6, 533-550.
29. Silverstein, A.M., Uhr, J.W. and Kraner, K.L. (1963) Fetal response to antigenic stimulus II. Antibody production by the fetal lamb. J. Exp. Med., 117, 799-812.
30. Silverstein, A.M., Prendergast, R.A. and Kraner, K.L. (1964) Fetal response to antigenic stimulus IV. Rejection of skin homografts by the fetal lamb. J. Exp. Med., 119, 955-964.
31. Thilaganathan, B., Carroll, S.G., Plachouras, N. et al. (1994) Fetal immunological and haematological changes in intrauterine infection. Br. J. Obstet. Gynaecol., 101, 418-421.
32. Touraine, J.L. (1992) In-utero transplantation of fetal liver stem cells into human fetuses. Hum. Reprod., 7, 44-48.
33. van Furth, R., Henrica, M.D., Schuit, R.E. et al. (1965) The immunological development of the human fetus. J. Exp. Med., 122, 1173-1191.
34. Vincent, M., Baughman, R., Trapnell, B.C. et al. (1995) Adenovirus-mediated gene transfer to the respiratory tract of fetal sheep in utero. Hum. Gene Ther., 6, 1019-1028.
35. West, L.J., Morris, P.J. and Wood, K.J. (1994) Fetal liver haematopoietic cells and tolerance to organ allografts. Lancet, 343, 148-149.
36. Westgren, M. and Ringden, O. (1994) Fetal to fetal transplantation. Acta Obstet. Gynecol. Scand., 73, 371-372.
37. Zanjani, E.D., Pallavicini, M.G., Ascensao, J.L. et al. (1992) Engraftment and long-term expression of human fetal hemapoietic stem cells in sheep following transplantation in utero. J. Clin. Invest., 89, 1178-1188.
38. Zsengeller, Z.K., Wert, S.E., Hull, W.M. et al. (1995) Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice. Hum. Gene Ther., 6, 457-467.